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EPISTASIS
EPISTASIS

... determined by the alleles G and g. The genes for albinism are a separate set of alleles. These genes are either A or a. Key: G = gray g = black A = color or pigment is present a = color or pigment is absent Because we’re talking about two different genes, the genotype written for an animal would hav ...
Unique X-linked familial FSGS with co
Unique X-linked familial FSGS with co

... * A histological diagnosis of the renal pathology is unavailable for these four affected males as they died prior to the development of renal biopsy as a routine clinical investigation in the regions they were residing. ...
Rice 5 S Ribosomal RNA and Its Binding Protein Genes: Structure
Rice 5 S Ribosomal RNA and Its Binding Protein Genes: Structure

... yeast, Xenopus laevis, and Drosophila. However, there are only a few reported sequences of cytoplasmic ribosomal proteins in plants while many sequences of organellar ribosomal proteins are known (Subramanian et al., 1990). In the case of plant ribosomal 5 S RNAbinding proteins (L5), there are only ...
Maternal effect genes
Maternal effect genes

... Nurse cells surrounding the oocyte in the ovarian follicle provide it with large amounts of mRNAs and proteins, some of which become localised in particular sites. The oocyte produces a local signal, which induces follicle cells at one end to become posterior follicle cells. The posterior follicle c ...
Patterns of Evolution
Patterns of Evolution

Introduction to self-assembly Self
Introduction to self-assembly Self

... to bind GTP, an experiment which has already been performed using an exhaustive covering of the sequence space for 24-nt RNAs (Jiménez et al., 2014). Longer RNAs capable of extending a dsRNA overhang up to their own length have been evolved through directed evolution (see e.g. Attwater et al., 2013 ...
OSIRIS: a tool for retrieving literature about sequence variants
OSIRIS: a tool for retrieving literature about sequence variants

... in-del, etc.), its position in the sequence and the alternative alleles are given. Finally, the list of articles found for each variant, and a list of articles that result from a ‘generic’ search are provided (see the Methods section for details). All data are provided with their corresponding links ...
Calmodulin Mutations Associated With Recurrent Cardiac Arrest in
Calmodulin Mutations Associated With Recurrent Cardiac Arrest in

... and none in CALM2 were called in 8,599 alleles of European ancestry by the Exome Sequencing Project ...
RiboMAX(TM) Large Scale RNA Production Systems
RiboMAX(TM) Large Scale RNA Production Systems

... In vitro transcription reactions are used to synthesize microgram amounts of RNA probes from recombinant DNA templates. Most transcription reactions designed to generate RNA probes are optimized to maximize incorporation of radiolabeled ribonucleotides rather than to produce large amounts of RNA. Ho ...
Gill: Transcription Regulation I
Gill: Transcription Regulation I

... gene in place of gene X, and measure regulatory domain expression. You can then continue to delete or mutate individual enhancers. http://cs273a.stanford.edu [BejeranoFall13/14] ...
Population Genetics Program on West Nile Virus
Population Genetics Program on West Nile Virus

... • The entire sequence of DNA (across all chromosomes) of a particular species. Gene – • A segment of DNA composed of a transcribed region and a regulatory sequence that makes transcription possible. Genetic locus – • Loose term with several interpretations. Often: the specific location of a gene on ...
RNA polymerase I
RNA polymerase I

... genome, these genes are regulated such that they are all turned on or off together. Grouping related genes under a common control mechanism allows bacteria to rapidly adapt to changes in the environment, switching from metabolizing one substrate to another quickly and energetically efficiently. For ...
Slide 1
Slide 1

... Mutations can change the meaning of genes 2. Mutations can result in deletions or insertions that may – alter the reading frame (triplet grouping) of the mRNA, so that nucleotides are grouped into different codons – This leads to significant changes in amino acid sequence downstream of the mutation ...
Review for Heredity Unit
Review for Heredity Unit

... 11. Different forms of a characteristic like blue eyes are _____________________ 12. When more than one allele is dominant as in blood types. ___________________ 13. The area of science that studies heredity is ______________________ ...
Types of Chromosome Mutations
Types of Chromosome Mutations

... Position-effect variegation is exhibited by this w+/w heterozygote. Wild-type allele is no longer wild-type in its expression in some of the eye facets. Any chromosomal change that places a locus next to heterochromatin can result in inactivation of that gene. ...
Link to Powerpoint
Link to Powerpoint

... Question we tackle today • What do we mean by a gene? • Steve Mount (ongenetics.blogspot.com): “A gene is all of the DNA elements required in cis for the properly regulated production of a set of RNAs whose sequences overlap in the genome. ” • Mark Gerstein (2007, Genome Biology): “The gene is a un ...
Document
Document

... RNA polymerase II transcribes protein-encoding genes, or messenger RNAs, which are the RNAs that get translated into proteins. Also, most snRNA (splicing) and microRNAs (RNAi). This is the most studied type, and due to the high level of control required over transcription a range of transcription fa ...
Sequence Analysis of the y-Globin Gene Locus from
Sequence Analysis of the y-Globin Gene Locus from

... American blacks (HPFH-1) is that the sequences juxtaposed to the y-globin genes as a result of the deletion contain an enhancer-like element that serves to maintain a transcriptionally active domain. A small fragment of D N A from the region immediately 3’ to the breakpoint in HPFH-1 has been found ...
Cengage Learning
Cengage Learning

... Useful References for Impacts/Issues The latest references for topics covered in this section can be found at the book companion website. Log in to the book’s e-resources page at www.thomsonedu.com to access InfoTrac articles. ...
GUDMAP Crym analysis
GUDMAP Crym analysis

... transgenic mice to address whether any of the transgenic lines that have been generated would be appropriate to study renal development. The analysis here provides the kidney research community with basic information as to the utility of GENSAT transgenic strains in furthering the study of kidney de ...
Learned Behaviors vs Inherited Traits
Learned Behaviors vs Inherited Traits

... dogs/cat being house trained, beware stay away of predators, not to mess with porcupine, climbing trees, to be aware of environmental issues, hunt for food, way to eat ...
Digital PCR Multiplexing Assay for Gene Copy Number
Digital PCR Multiplexing Assay for Gene Copy Number

... number levels. Copy Number Variation The DNA copy number of a genomic locus is the number of copies of the DNA in that region relative to either a single control sample or a pooled reference population. Copy number variations (CNVs) include loci gains or losses, and have been associated with familia ...
SYSCILIA Newsletter 7 – September 2012
SYSCILIA Newsletter 7 – September 2012

... Dr. James Battey, director of the US National Institute on Deafness and Other Communications Disorders said: "These results could lead to one of the first therapeutic options for treating people with congenital anosmia. They also set the stage for therapeutic approaches to treating diseases that inv ...
Gregor Mendel
Gregor Mendel

... 6.4 Traits, Genes, and Alleles • Alleles can be represented using letters. – A dominant allele is expressed as a phenotype when at least one allele is dominant. – A recessive allele is expressed as a phenotype only when two copies are ...
letters - Lewis-Sigler Institute | for Integrative Genomics
letters - Lewis-Sigler Institute | for Integrative Genomics

... Interactions between polymorphisms at different quantitative trait loci (QTLs) are thought to contribute to the genetics of many traits, and can markedly affect the power of genetic studies to detect QTLs1. Interacting loci have been identified in many organisms1–5. However, the prevalence of intera ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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