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B Supplementary Figure 2
B Supplementary Figure 2

... of another flowering gene FLC, while the role of FLC is to repress flowering. (MiHye Lim et al 2004, Scott D. Michaels and Richard M. Amasino 1999). Actin (ACT2) is used as the internal control, so each tissue’s transcription level was normalized against actin. WT untreated group was set to 1.0 for ...
Mouse Models of Cancer - Institute for Cancer Genetics
Mouse Models of Cancer - Institute for Cancer Genetics

... Can control time and place of expression Tighter than tet-induced systems ...
ppt
ppt

... • RE often cleave staggered sites, leaving overhanging single-stranded regions (5’-PO4: 3’-OH) • DNA ligase seals ends (5’-PO4: 3’-OH) ...
Sordaria Meiosis and Crossing Over Lab Name Objective: To
Sordaria Meiosis and Crossing Over Lab Name Objective: To

... tetrad consisting of the two parental sister chromatids. It is during this stage that genes or chromosomal fragments will swap places. The newly recombined tetrads are then pulled apart during meiosis I to yield two diploid daughter cells each containing a recombined chromosome. Finally, the diploid ...
Biology 30 Patterns and Probabilities
Biology 30 Patterns and Probabilities

... Suppose you are studying two genes and crossing over occurs between them then the alleles will end up on separate chromosomes and will therefore migrate into different gametes. Crossing over is more likely to occur between genes that are farther apart on a chromosome than between genes that are clos ...
Alternative Splicing: How to Get More than One Protein from a Gene
Alternative Splicing: How to Get More than One Protein from a Gene

... demonstrate how eukaryotic cells may use one DNA sequence to code for multiple proteins. Eukaryotic cells might use the same gene or DNA sequence differently depending on where the gene is located. A brain cell might make a protein from the same gene differently than an eye cell by splicing the mRNA ...
translation ppt
translation ppt

... Elongation continues. The polypeptide chain continues to grow. ...
Slide 1
Slide 1

... • Bootstrap Aggregating (Bagged) Logic Regression is a new technique that may be useful in analyzing SNP associations. • Bagged Logic Regression identified “Worst-Least” CFS SNP genes consistent with exhaustive search by Goertzel, et al (2006). • “Interesting” SNPs did not show statistically signifi ...
Comparative Analysis
Comparative Analysis

... hits. BLAST uses a heuristic algorithm which seeks local as opposed to global alignments and is therefore able to detect relationships among sequences which share only isolated regions of similarity (Altschul et al., 1990). ...
Methods S2.
Methods S2.

... exons and seven introns. Polymorphisms in this gene may alter glycosylase function and an individual’s ability to repair damaged DNA, possibly resulting in genetic instability that can foster carcinogenesis [9]. Among many polymorphisms identified in the hOGG1 gene, much interest has been focused on ...
Network Reconstruction Slides
Network Reconstruction Slides

... • Genetic Gene overexpression and purification, gene deletions. ...
Inheritance
Inheritance

... Dickens Moment (Dominant and recessive genes) One day in the ag room, the two brothers Dominant and Recessive Gene walked in. They were arguing with each other as usual. Recessive was upset with Dominant because he is the one that is always noticed. Recessive is tired of living in Dominant’s shadow ...
probability laws
probability laws

... MENDEL’S LAWS 1. Alternative versions of genes (alleles) account for variations in inherited characters. 2. For each character, an organism inherits two alleles, one from each parent. 3. If the 2 alleles differ, then one, the dominant allele is fully expressed in the organism’s appearance; the rece ...
Unit 1 Notes #8 Other Mechanisms of Evolution - Mr. Lesiuk
Unit 1 Notes #8 Other Mechanisms of Evolution - Mr. Lesiuk

... and 750 blue marbles. A handful of 30 or so marbles may or may not perfectly conform to the 3:1 ratio in the bucket. In fact, the smaller the sample, the less representative the sample will be of the normal distribution. Example: A handful of 12 marbles maybe 10 red : 2 blue, or another sample of 12 ...
Gene Section MYST3 (MYST histone acetyltransferase (monocytic leukemia) 3
Gene Section MYST3 (MYST histone acetyltransferase (monocytic leukemia) 3

... 2004 amino acids; 225 kDa; composed from N-term of: a NEMM domain (N-term region of ENOK, MOZ or MORF) including a H15 (linker H1 and H5 like) nuclear localization domain, 2 PHD (plant homeodomain, also known as LAP (leukemia ...
Genetics of Viruses and Bacteria
Genetics of Viruses and Bacteria

... Conjugation • Direct transfer of genetic material (usually plasmid DNA) from two bacterial cells that are temporarily joined by a sex pili. • Plasmid genes are not required for survival, but they tend to code for genes that increase fitness (ex. antibiotic resistance) video ...
Print this article - Annals of Gastroenterology
Print this article - Annals of Gastroenterology

Vocabulary Review
Vocabulary Review

... A genotype having one dominant and one recessive allele HETEROZYGOUS ...
Ribosome Profiling Provides Evidence that Large Please share
Ribosome Profiling Provides Evidence that Large Please share

... excludes a small group of 7 genes that have non-conserved long ORFs but have been annotated as putative protein-coding genes based on homology to other proteins (see Methods). ...
Deletion of GLI3 supports the homology of the human Greig
Deletion of GLI3 supports the homology of the human Greig

... Xtl + mice prevents the formation of a functional protein product from one allele. Therefore, a reduction in gene dosage for GLI3 is the likely cause for the malformations seen in both, the mouse Xt mutant and the human GCPS syndrome, confirming the homology of these syndromes. As the integration si ...
Patterns of Gene Inheritance
Patterns of Gene Inheritance

...  Certain traits follow the rules of simple Mendelian inheritance (i.e., dominant-recessive type of inheritance), but other inheritance patterns exist for many traits Multiple Alleles: more than two alleles control a particular trait For example: blood type  Blood types: A, B, AB, and O are phenoty ...
Background Autism spectrum disorder (ASD) is a
Background Autism spectrum disorder (ASD) is a

... consistently shown that they may play a role in ASD [15–18]. Nevertheless, the impact of de novo mutations is not as relevant as the one brought by inheritance: it was estimated that 49% of the genetic architecture of ASD is related to common inherited variants, 3% by de novo mutations and 3% by rar ...
DNA/RNA
DNA/RNA

... – Attached to Endoplasmic Reticulum (Rough ER) ...
Novel Genetic Strategies for Cystinosis
Novel Genetic Strategies for Cystinosis

... genome editing by creation of double-stranded breaks in DNA and subsequent repair by endogenous DNA repair machinery. Repair can occur via either non-homologous end joining (NHEJ), which involves error-prone repair without a template, or homology-directed repair (HDR), in which a donor template with ...
Document
Document

... All the genes contained by the individuals of population constitute the gene pool To understand the genetics of evolution, we study the gene pool of a population rather than the genotypes of its individual members Quantitative measures of the gene pool ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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