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Solid Tumour Section Angiomatoid fibrous histiocytoma (AFH) Atlas of Genetics and Cytogenetics
Solid Tumour Section Angiomatoid fibrous histiocytoma (AFH) Atlas of Genetics and Cytogenetics

... step in the transformation process, but the overall gene expression patterns are likely to vary considerably between AFH and CCS, in keeping with their clinopathologic differences. EWS/ATF1 functions as a potent constitutive activator of several cAMP-inducible promoters when assayed by transfection ...
DNA from the beginning: Part 2
DNA from the beginning: Part 2

... 6. Animation: What happened to the sea urchin eggs that had the triple set of chromosomes (polyploidy)? 6. Gene’s Question: Why is polyploidy possible and common in plants? ...
Text S1, DOCX file, 0.03 MB
Text S1, DOCX file, 0.03 MB

Chapter 11 Genetics
Chapter 11 Genetics

... H. Refers to an individual’s observable traits I. Refers to the particular genes an individual carries 9. _____ recessive allele J. When the effect of an allele on a trait masks that of 10. _____ homozygous any recessive allele paired with it K. When both alleles of a pair are identical 11. _____ P, ...
Dragon Genetics
Dragon Genetics

... To test whether baby dragons with wings and baby dragons without wings will be equally likely to have big horns, you will carry out a simulation of the simultaneous inheritance of the genes for wings and horns. Since the father is homozygous (wwhh), you know that all of the father's sperm will be wh ...
detection and pathogenetic role of mmr missense mutations
detection and pathogenetic role of mmr missense mutations

... germline mutations in one of the corresponding MMR genes, mostly MLH1 (50%) or MSH2 (39%). MMR is a multi-enzymatic system which contributes to genomic stability maintenance, by correcting mismatched base pairs or slippages in repeated sequences generated during DNA replication. Approximately 30% of ...
1418 K - Iranian Journal of Basic Medical Sciences
1418 K - Iranian Journal of Basic Medical Sciences

Leukaemia Section t(2 14)(p13-16 32)
Leukaemia Section t(2 14)(p13-16 32)

... myeloid leukemias in mice and lymphoid malignancies in humans; the conserved N-terminus of BCL11A. deregulated expression of BCL11A may play a major role in the pathogenesis; gains and amplifications of the region of chromosome 2p13-16 have been reported in B-cell malignancies, REL, a NF-kappaB gene ...
The ocean as regional enabler A Pacific Northwest success
The ocean as regional enabler A Pacific Northwest success

... • Limited knowledge about composition of microbial communities; • High complexity and temporal changes of microbial metabolism; • Paucity of genomic sequence information for environmental microbes. ...
Study Guide for Exam 3
Study Guide for Exam 3

... 8. Explain where the different types of RNA are found: mRNA, rRNA, and tRNA 9. Be able to accurately use the codon table to predict the amino acid sequence of a protein. 10. Explain how mutations affect protein synthesis. 11. Recognize examples of silent mutations. 12. Recognize examples of insertio ...
AP Chapter 14 Lecture - TJ
AP Chapter 14 Lecture - TJ

... CHAPTER 14 MENDEL & THE GENE IDEA 14.1 Mendel used the scientific approach to identify two laws of inheritance ...
Population Genetics - cK-12
Population Genetics - cK-12

... Darwin knew that heritable variations are needed for evolution to occur. However, he knew nothing about Mendel’s laws of genetics. Mendel’s laws were rediscovered in the early 1900s. Only then could scientists fully understand the process of evolution. We now know that variations of traits are herit ...
BIOLOGY - Learner
BIOLOGY - Learner

... molecular and morphological characters, molecular data provides several advantages. First, molecular data offers a large and essentially limitless set of characters. Each nucleotide position, in theory, can be considered a character and assumed independent. The DNA of any given organism has millions ...
RNAi: nature abhors a double-strand György Hutvágner and Phillip
RNAi: nature abhors a double-strand György Hutvágner and Phillip

... Dicer, development, and small temporal RNAs Mutations in some genes required for RNAi and in orthologs of these genes have dramatic developmental defects, especially in the germline or in proliferative tissues, suggesting a link between the RNAi pathway and development [39–46]. Mutations in the worm ...
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... M. weeds that are very similar to the crop plants can be controlled; Possible harmful effects: N. some gene transfers are regarded as potentially harmful to organism (especially animals); O. release of genetically engineered organisms in the environment; P. can spread and compete with the naturally ...
Sequencing the World of Possibilities for Energy & Environment
Sequencing the World of Possibilities for Energy & Environment

...  We have main archives (Genbank), and currated databases (Refseq, SwissProt), and protein classification database (COG, Pfam).  This is the tip of the iceberg.  They help predict the function, or the network of functions.  Systems that integrate the information from several databases, visualize ...
Chapter 7 Molecular Genetics: From DNA to Proteins
Chapter 7 Molecular Genetics: From DNA to Proteins

... The double helix shape of DNA, together with Chargaff’s rules, led to a better understanding of DNA. DNA, as a nucleic acid, is made from nucleotide monomers, and the DNA double helix consists of two polynucleotide chains. Each nucleotide consists of a sugar (deoxyribose), a phosphate group, and a ni ...
Gene Section EIF3A (eukaryotic translation initiation factor 3, subunit A)
Gene Section EIF3A (eukaryotic translation initiation factor 3, subunit A)

... chemotherapy, suggesting that lung cancer patients with higher eIF3a expression level respond better to platinum-based chemotherapy (Yin et al., unpublished findings). Oncogenesis eIF3a was over-expressed in all types of human lung cancer. Furthermore, it is ubiquitously highly expressed in prolifer ...
Guidelines for Genetic Nomenclature and Community Governance
Guidelines for Genetic Nomenclature and Community Governance

... 4. Different genes with the same phenotype, which bear the same three-letter symbol, will be distinguished by a number following the three letters (e.g., dmi1 versus dmi2). 5. Different alleles of the same gene will be distinguished by different numbers following the symbol, locus number, and a hyph ...
Subtle Accents
Subtle Accents

... Apply the law of probability to determine patterns of inheritance with a punnett square Understand the difference between complete and incomplete dominance ...
Dr Paul Jaschke
Dr Paul Jaschke

... but one feature that has puzzled and intrigued scientists over the years is the fact that many of its genes are overlapped with each other. This creates a genome with highly compressed information analogous to what happens when music gets compressed into an MP3 file. Several years ago the genome of ...
Mouse Models of Cancer - Institute for Cancer Genetics
Mouse Models of Cancer - Institute for Cancer Genetics

... Can control time and place of expression Tighter than tet-induced systems ...
ppt
ppt

... • RE often cleave staggered sites, leaving overhanging single-stranded regions (5’-PO4: 3’-OH) • DNA ligase seals ends (5’-PO4: 3’-OH) ...
Sordaria Meiosis and Crossing Over Lab Name Objective: To
Sordaria Meiosis and Crossing Over Lab Name Objective: To

... tetrad consisting of the two parental sister chromatids. It is during this stage that genes or chromosomal fragments will swap places. The newly recombined tetrads are then pulled apart during meiosis I to yield two diploid daughter cells each containing a recombined chromosome. Finally, the diploid ...
Biology 30 Patterns and Probabilities
Biology 30 Patterns and Probabilities

... Suppose you are studying two genes and crossing over occurs between them then the alleles will end up on separate chromosomes and will therefore migrate into different gametes. Crossing over is more likely to occur between genes that are farther apart on a chromosome than between genes that are clos ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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