Text S13.
... Due to the substantial per-codon variability of ribosomal densities, we pooled different codons together to estimate the effect size of each factor concerned. These analyses were first conducted within each gene to avoid estimating translation initiation rates. The median or mean value among all gen ...
... Due to the substantial per-codon variability of ribosomal densities, we pooled different codons together to estimate the effect size of each factor concerned. These analyses were first conducted within each gene to avoid estimating translation initiation rates. The median or mean value among all gen ...
Ribosome profiling reveals post-transcriptional buffering of divergent
... Methods). Count-based tests were applied to identify statistically significant differences using 5% false discovery rate (FDR) and 1.5-fold minimum thresholds in both replicates. Our biological replicates were well correlated for both mRNA and RPF libraries (r > 0.97) (Supplemental Fig. S2). By requ ...
... Methods). Count-based tests were applied to identify statistically significant differences using 5% false discovery rate (FDR) and 1.5-fold minimum thresholds in both replicates. Our biological replicates were well correlated for both mRNA and RPF libraries (r > 0.97) (Supplemental Fig. S2). By requ ...
Applications of Genomics
... human genome, most of which encode proteins or components of proteins. What makes each person unique is a large number of DNA variants distributed throughout the genome. Some people have particular DNA variants that can predispose them to cardiovascular disease or stroke. These variants often requir ...
... human genome, most of which encode proteins or components of proteins. What makes each person unique is a large number of DNA variants distributed throughout the genome. Some people have particular DNA variants that can predispose them to cardiovascular disease or stroke. These variants often requir ...
Extensive tissue-specific transcriptomic plasticity in maize primary
... function of the random and fixed effects for each combination of tissue and treatment. Each normalization factor was calculated by adding the log of the TMM normalization factor (Robinson and Oshlack, 2010) for each sample to the fitted value of a smoother on the log of the mean of the raw counts us ...
... function of the random and fixed effects for each combination of tissue and treatment. Each normalization factor was calculated by adding the log of the TMM normalization factor (Robinson and Oshlack, 2010) for each sample to the fitted value of a smoother on the log of the mean of the raw counts us ...
Environmental reservoirs of antibiotic resistance genes
... • CTX-M-15 is carried throughout a wide range of genetic contexts and plasmids • Contexts were seen in human pathogens, including several novel genetic contexts ...
... • CTX-M-15 is carried throughout a wide range of genetic contexts and plasmids • Contexts were seen in human pathogens, including several novel genetic contexts ...
genetics: the code broken
... ‘regulatory’ genes, which produce proteins that can control the transcription stage and other aspects of protein synthesis. Characteristics can be determined by more than one pair of alleles (‘multiple alleles’) within a gene pair; examples of this include the inheritance of blood groups and Rh anti ...
... ‘regulatory’ genes, which produce proteins that can control the transcription stage and other aspects of protein synthesis. Characteristics can be determined by more than one pair of alleles (‘multiple alleles’) within a gene pair; examples of this include the inheritance of blood groups and Rh anti ...
Cover Page The handle http://hdl.handle.net/41480 holds
... gene expression studies. Microarrays reveal expression profiles for a large number of genes at different time points. A single array or "chip" may contain probes to determine transcript levels for every known gene in the genome of one or more organisms [Wel07]. Alternatively, "tag based" technologie ...
... gene expression studies. Microarrays reveal expression profiles for a large number of genes at different time points. A single array or "chip" may contain probes to determine transcript levels for every known gene in the genome of one or more organisms [Wel07]. Alternatively, "tag based" technologie ...
Gene Section PRUNE (prune exopolyphosphatase) Atlas of Genetics and Cytogenetics
... Prune, a 62 kDa protein, belongs to the DHH family phosphoesterase proteins including RecJ DNA repair exonucleases, pyrophosphatases (PPASEs) and exopolyphospatases (PPX). The DHH super-family can be divided into two main groups on the basis of a Cterminal motif that is very well conserved within ea ...
... Prune, a 62 kDa protein, belongs to the DHH family phosphoesterase proteins including RecJ DNA repair exonucleases, pyrophosphatases (PPASEs) and exopolyphospatases (PPX). The DHH super-family can be divided into two main groups on the basis of a Cterminal motif that is very well conserved within ea ...
A minimal gene set for cellular life derived by comparison of
... except those that are indispensable for cell function, could have been conserved through the 1.5 billion years or more separating H. influenzae and M. genitalium from their last common ancestor, given that the evolution in both lineages has been replete with gene elimination (1–4). Therefore, the or ...
... except those that are indispensable for cell function, could have been conserved through the 1.5 billion years or more separating H. influenzae and M. genitalium from their last common ancestor, given that the evolution in both lineages has been replete with gene elimination (1–4). Therefore, the or ...
Early Ideas of Heredity
... 1866: Mendel published “hereditary factors” passed from parent to offspring 1859: Darwin published Theory of Evolution by Natural Selection ...
... 1866: Mendel published “hereditary factors” passed from parent to offspring 1859: Darwin published Theory of Evolution by Natural Selection ...
Exploring Gene Therapy.indd
... functional copy. It is important that they understand this is not the case. Gene therapy endeavors to add a functional copy of the gene of interest in the hope that its function will counteract the effect of the faulty gene. ...
... functional copy. It is important that they understand this is not the case. Gene therapy endeavors to add a functional copy of the gene of interest in the hope that its function will counteract the effect of the faulty gene. ...
Jody Rosnik - ED591geneticslesson
... there is one dominant gene and one recessive gene in a gene pair, the color will be what the dominant gene says. This is the dominant/recessive relationship. Using the Punnett Square: To illustrate the combining of chromosomes scientists use a model called the Punnett Square. We can see through the ...
... there is one dominant gene and one recessive gene in a gene pair, the color will be what the dominant gene says. This is the dominant/recessive relationship. Using the Punnett Square: To illustrate the combining of chromosomes scientists use a model called the Punnett Square. We can see through the ...
Morgan, Thomas H. The Theory of the Gene. The American
... and sperms, with the problems concerning the subsequent action of these genes in the development of the embryo. What genes stand for can be most easily shown by means of a few familiar illustrations. Mendel’s cross with yellow and green peas (or any similar case in which two characters are contraste ...
... and sperms, with the problems concerning the subsequent action of these genes in the development of the embryo. What genes stand for can be most easily shown by means of a few familiar illustrations. Mendel’s cross with yellow and green peas (or any similar case in which two characters are contraste ...
Chromosomes and Genes - hrsbstaff.ednet.ns.ca
... The remaining pair of human chromosomes consists of the sex chromosomes, X and Y. Females have two X chromosomes, and males have one X and one Y chromosome. In females, one of the X chromosomes in each cell is inactivated and known as a Barr body. This ensures that females, like males, have only one ...
... The remaining pair of human chromosomes consists of the sex chromosomes, X and Y. Females have two X chromosomes, and males have one X and one Y chromosome. In females, one of the X chromosomes in each cell is inactivated and known as a Barr body. This ensures that females, like males, have only one ...
Genotypes to Phenotypes
... 1-3 Be able to explain, interpret, and predict the biochemical mechanisms by which cells express their genotypes to produce phenotypes (BT=5) 1-4 Be able to evaluate and predict the impact of epistatic gene interactions on phenotypes (BT=6) ...
... 1-3 Be able to explain, interpret, and predict the biochemical mechanisms by which cells express their genotypes to produce phenotypes (BT=5) 1-4 Be able to evaluate and predict the impact of epistatic gene interactions on phenotypes (BT=6) ...
Metabolomic and Gene Expression Profiles Exhibit Modular Genetic
... standards were run at the beginning, middle, and end of each day to generate a standard curve, and PMIX standards were run at the beginning and end to allow for retention time calibration (Kovats retention index). Chromatograms were aligned and molecular targets were called with AnalyzerPro (http:// ...
... standards were run at the beginning, middle, and end of each day to generate a standard curve, and PMIX standards were run at the beginning and end to allow for retention time calibration (Kovats retention index). Chromatograms were aligned and molecular targets were called with AnalyzerPro (http:// ...
Genetics Terms You’ve Gotta Know
... Homozygous: two alleles for a gene that are the SAME Heterozygous: two alleles for a gene that are DIFFERENT You get one allele from your mom and one from your dad. If you get the same from your mom and dad, you are homozygous for that trait. If your mom gave you a different allele than your ...
... Homozygous: two alleles for a gene that are the SAME Heterozygous: two alleles for a gene that are DIFFERENT You get one allele from your mom and one from your dad. If you get the same from your mom and dad, you are homozygous for that trait. If your mom gave you a different allele than your ...
Biology 30 - Patricia Schwandt Courses
... (membranes, organelles, nucleic acids). Cells are responsible for producing their own proteins. The blueprint for the protein is contained in the nucleus (DNA) and the protein is manufactured in the ribosome. By linking defective enzymes (protein molecules) to genetic mutations scientists Beadle & T ...
... (membranes, organelles, nucleic acids). Cells are responsible for producing their own proteins. The blueprint for the protein is contained in the nucleus (DNA) and the protein is manufactured in the ribosome. By linking defective enzymes (protein molecules) to genetic mutations scientists Beadle & T ...
Final Mendelian concepts
... • Mendel did not know about chromosomes when he proposed the Law of Independent Assortment. • The pea traits he studied happened to be located on different chromosomes – so they did assort independently. ...
... • Mendel did not know about chromosomes when he proposed the Law of Independent Assortment. • The pea traits he studied happened to be located on different chromosomes – so they did assort independently. ...
Recombinant DNA Activity
... staggered cut of the DNA producing sticky ends or single strands of unpaired nucleotide bases capable of binding with complementary sticky ends. By using restriction enzymes that will cut the DNA on either side of the gene, the desired gene can be clipped out of the DNA strand. 3. Once the desired g ...
... staggered cut of the DNA producing sticky ends or single strands of unpaired nucleotide bases capable of binding with complementary sticky ends. By using restriction enzymes that will cut the DNA on either side of the gene, the desired gene can be clipped out of the DNA strand. 3. Once the desired g ...
Genetics
... genes (homozygous). • Hybrids have mixed genes for the same trait (heterozygous). • Gametes only carry one allele for each trait (they are haploid) ...
... genes (homozygous). • Hybrids have mixed genes for the same trait (heterozygous). • Gametes only carry one allele for each trait (they are haploid) ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.