Document
... • polyploidy is common in plants - but not animals • polyploids are more normal in appearance than aneuploids • large-scale chromosomal alterations in humans and other mammals often lead to spontaneous abortions (miscarriages) or cause a variety of developmental disorders – plants tolerate such gene ...
... • polyploidy is common in plants - but not animals • polyploids are more normal in appearance than aneuploids • large-scale chromosomal alterations in humans and other mammals often lead to spontaneous abortions (miscarriages) or cause a variety of developmental disorders – plants tolerate such gene ...
Pp - susanpittinaro
... Mendel was wise & lucky to chose peas • Peas plants are good for genetic research – Relatively simple genetically – most characteristics are controlled by a single gene with each gene having only 2 alleles • One completely dominant over the other ...
... Mendel was wise & lucky to chose peas • Peas plants are good for genetic research – Relatively simple genetically – most characteristics are controlled by a single gene with each gene having only 2 alleles • One completely dominant over the other ...
Activation of Silent Genes by Transposons Tn5 and TnlO
... expressed gene, but the general phenomenon is difficult to interpret, since not all insertions of a given element serve to activate distal genes (SAEDLER et al. 1974). As exemplified by IS2, several factors complicate the situation. Rearrangementswithin the element can generate a promoter activity d ...
... expressed gene, but the general phenomenon is difficult to interpret, since not all insertions of a given element serve to activate distal genes (SAEDLER et al. 1974). As exemplified by IS2, several factors complicate the situation. Rearrangementswithin the element can generate a promoter activity d ...
The MAOA Gene Predicts Credit Card Debt ∗ London School of Economics
... implicated. As a result, scientists typically start with “candidate” genes that are known to influence related behaviors or processes in the body. For social behavior, this means focusing on genes that affect brain development, neurotransmitter synthesis and reception, hormone regulation, and trans ...
... implicated. As a result, scientists typically start with “candidate” genes that are known to influence related behaviors or processes in the body. For social behavior, this means focusing on genes that affect brain development, neurotransmitter synthesis and reception, hormone regulation, and trans ...
Developing a Gene Therapy for Motor Neuron Disease
... In untreated cells, SOD1 protein is made as shown on the right along the blue pathway: The SOD1 gene is copied into a messenger RNA which contains the instruction to make SOD1 protein. The SOD1 mRNA is exported to the cytoplasm and translated into SOD1 protein which is toxic in SOD1 MND. What happen ...
... In untreated cells, SOD1 protein is made as shown on the right along the blue pathway: The SOD1 gene is copied into a messenger RNA which contains the instruction to make SOD1 protein. The SOD1 mRNA is exported to the cytoplasm and translated into SOD1 protein which is toxic in SOD1 MND. What happen ...
Guidelines for interpretation of 16S rRNA gene sequence
... sequence homogeneity in different strains of that species becomes very important in determining whether 16S rRNA gene sequencing is able to identify the bacterium to the species level. More importantly, medically important bacterial species with similar 16S rRNA gene sequences were also identified ( ...
... sequence homogeneity in different strains of that species becomes very important in determining whether 16S rRNA gene sequencing is able to identify the bacterium to the species level. More importantly, medically important bacterial species with similar 16S rRNA gene sequences were also identified ( ...
Review Article
... the importance of certain individual virulence factors in pathogenicity, this work identified a pleiotropically negative avirulent phenotype, designated Vir-, where a single Tn5 insertion prevented the expression of multiple virulence factors, including PTX, ACT, FHA and HLT. Weiss et al. (1983) sug ...
... the importance of certain individual virulence factors in pathogenicity, this work identified a pleiotropically negative avirulent phenotype, designated Vir-, where a single Tn5 insertion prevented the expression of multiple virulence factors, including PTX, ACT, FHA and HLT. Weiss et al. (1983) sug ...
What Are Lethal Whites?
... Lethal Whites can only result from a merle to merle breeding, but not every puppy in the litter is a homozygous (MM) white. Statistics indicate that approximately 25% of the litter will be homozygous pups. The pups may show signs of deafness, blindness or a combination of the two, however it should ...
... Lethal Whites can only result from a merle to merle breeding, but not every puppy in the litter is a homozygous (MM) white. Statistics indicate that approximately 25% of the litter will be homozygous pups. The pups may show signs of deafness, blindness or a combination of the two, however it should ...
Molecular evidence for the existence of additional members of the
... convalescent phases) and from four healthy controls working in the same workplace were collected. Mononuclear cells purified from 2.5 ml blood using Histopaque (Sigma-Aldrich) were centrifuged in a microcentrifuge and the pellet was processed as described above. Vessel wall tissue was obtained from ...
... convalescent phases) and from four healthy controls working in the same workplace were collected. Mononuclear cells purified from 2.5 ml blood using Histopaque (Sigma-Aldrich) were centrifuged in a microcentrifuge and the pellet was processed as described above. Vessel wall tissue was obtained from ...
The chromatin remodelling factor Brg1 interacts with catenin to
... mediates transcriptional activation by virtue of potent transactivation domains present in the C-terminus of b-catenin (van de Wetering et al., 1997; Hecht et al., 1999). In the absence of nuclear b-catenin, Tcf factors occupy target gene promoters in a complex with p300/ CBP, CtBP and members of th ...
... mediates transcriptional activation by virtue of potent transactivation domains present in the C-terminus of b-catenin (van de Wetering et al., 1997; Hecht et al., 1999). In the absence of nuclear b-catenin, Tcf factors occupy target gene promoters in a complex with p300/ CBP, CtBP and members of th ...
Computational Biology
... Last lecture (mouse:man) we saw that many more genomic elements are conserved between related species than only the genes. Therefore, genome rearrangement studies that are based on genome-wide analysis of gene orders rather than individual genes, may provide a more general picture on evolution. In f ...
... Last lecture (mouse:man) we saw that many more genomic elements are conserved between related species than only the genes. Therefore, genome rearrangement studies that are based on genome-wide analysis of gene orders rather than individual genes, may provide a more general picture on evolution. In f ...
The science of replacing mitochondrial DNA and
... of mitochondrial genomes does not follow the regimented pattern of nuclear genomes, so a In our work using fruit flies, we ask how the mother that is healthy but carries some genomes compete with each other. You're putting mitochondrial disease mutations might pass on a into one arena competitors th ...
... of mitochondrial genomes does not follow the regimented pattern of nuclear genomes, so a In our work using fruit flies, we ask how the mother that is healthy but carries some genomes compete with each other. You're putting mitochondrial disease mutations might pass on a into one arena competitors th ...
Risks from GMOs due to Horizontal Gene Transfer
... et al., 2004), whereas the simplified conditions in laboratory studies probably lack many of the appropriate biotic and abiotic signals that facilitate HGT in nature (Mel and Mekalanos, 1996; Nielsen and van Elsas, 2001). For example, the presence of algae stimulates the release of bacterial plasmid ...
... et al., 2004), whereas the simplified conditions in laboratory studies probably lack many of the appropriate biotic and abiotic signals that facilitate HGT in nature (Mel and Mekalanos, 1996; Nielsen and van Elsas, 2001). For example, the presence of algae stimulates the release of bacterial plasmid ...
Perturbations ofDrosophila aActinin Cause Muscle Paralysis
... protease calpain release both a-actinin and actin intact . This result may imply that at least one additional protein facilitates binding ofactin to a-actinin, and raises questions as to how directly a-actinin participates in cross-link formation . To evaluate in vivo a-actinin functions and relate ...
... protease calpain release both a-actinin and actin intact . This result may imply that at least one additional protein facilitates binding ofactin to a-actinin, and raises questions as to how directly a-actinin participates in cross-link formation . To evaluate in vivo a-actinin functions and relate ...
MSH2
... insertion/deletion loops. • The loss of MMR, in this case via loss of MSH2, causes an accumulation of mutations. • An accumulation of mutations leads to tumorigenesis. • Cells dividing more rapidly, such as epithelial cells, will most likely develop cancer first. • Since colon epithelial cells divid ...
... insertion/deletion loops. • The loss of MMR, in this case via loss of MSH2, causes an accumulation of mutations. • An accumulation of mutations leads to tumorigenesis. • Cells dividing more rapidly, such as epithelial cells, will most likely develop cancer first. • Since colon epithelial cells divid ...
Association of MMP-3 (-1612 5A/6A) polymorphism with knee
... address this issue, we analyzed the influence of MMP-3 -1612 5A/6A polymorphism on the risk of knee OA in the Thai population. In this case–control study, our findings demonstrated that the percentage of the MMP-3 -1612 5A/ 6A polymorphism allele and the distribution of genotypes were not significan ...
... address this issue, we analyzed the influence of MMP-3 -1612 5A/6A polymorphism on the risk of knee OA in the Thai population. In this case–control study, our findings demonstrated that the percentage of the MMP-3 -1612 5A/ 6A polymorphism allele and the distribution of genotypes were not significan ...
pdf
... and the nucleotide sequence responsible for each terminal restriction fragment (T-RF) was determined by 16S rRNA gene cloning and sequencing [18]. Two major populations, one assigned to the genus Thauera, and another related to the genera Ralstonia and Limnobacter, were associated with 4-chlorobenzo ...
... and the nucleotide sequence responsible for each terminal restriction fragment (T-RF) was determined by 16S rRNA gene cloning and sequencing [18]. Two major populations, one assigned to the genus Thauera, and another related to the genera Ralstonia and Limnobacter, were associated with 4-chlorobenzo ...
Quantitative expression of cholera toxin mRNA in Vibrio cholerae
... respectively. The differences between arrangements C and A are: (i) the presence of two copies of the complete CTX in arrangement C, and (ii) the position of RS1 downstream of CTXW in arrangement C compared with upstream in arrangement A. The data support the suggestion that the position of RS1 may ...
... respectively. The differences between arrangements C and A are: (i) the presence of two copies of the complete CTX in arrangement C, and (ii) the position of RS1 downstream of CTXW in arrangement C compared with upstream in arrangement A. The data support the suggestion that the position of RS1 may ...
Article A Molecular Evolutionary Reference for the Human Variome
... each possible residue state at a given position in a species (species 1 in fig. 1), where the multispecies alignment is modified to replace the residue at the focal position with a missing data symbol (see Materials and Methods). Then, we compute multiple PP values by progressively pruning evolution ...
... each possible residue state at a given position in a species (species 1 in fig. 1), where the multispecies alignment is modified to replace the residue at the focal position with a missing data symbol (see Materials and Methods). Then, we compute multiple PP values by progressively pruning evolution ...
Arabidopsis transcriptional regulation by light stress via hydrogen
... all the high light responsive genes are controlled in the same manner as APX2. Early Light Inducible Protein (ELIP) was first identified as a protein that was transiently induced in the very early stages of the greening process in etiolated pea seedlings (a 24 000-Mr precursor protein (Meyer & Klopp ...
... all the high light responsive genes are controlled in the same manner as APX2. Early Light Inducible Protein (ELIP) was first identified as a protein that was transiently induced in the very early stages of the greening process in etiolated pea seedlings (a 24 000-Mr precursor protein (Meyer & Klopp ...
Virp1 Is a Host Protein with a Major Role in Potato - IMBB
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
GENES AND SPECIATION
... existence? These questions are some of the most enduring in biology and remain controversial today. Under many commonly accepted species definitions, speciation can be viewed as the process by which two identical populations diverge genetically to the point at which their subsequent merger would not ...
... existence? These questions are some of the most enduring in biology and remain controversial today. Under many commonly accepted species definitions, speciation can be viewed as the process by which two identical populations diverge genetically to the point at which their subsequent merger would not ...
Familial Breast/Ovarian Cancer service description
... are provided in the form of a written interpretive report based on whether or not a mutation has been identified and on the type of mutation found. Interpretation of results is based on current best practice guidelines for molecular genetics testing. Confirmation of the presence of a pathogenic muta ...
... are provided in the form of a written interpretive report based on whether or not a mutation has been identified and on the type of mutation found. Interpretation of results is based on current best practice guidelines for molecular genetics testing. Confirmation of the presence of a pathogenic muta ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.