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Orientation of the transcription factor binding
Orientation of the transcription factor binding

... Sites (TFBS) based on sequence data. One main difficulty in such computational predictions is the large number of false positives they generate. Here we examine the association of five features with TFBS and show that they differ between true binding sites and similar sequences that are predicted as ...
How to report IG sequence data in clinical Richard Rosenquist Uppsala, Sweden
How to report IG sequence data in clinical Richard Rosenquist Uppsala, Sweden

Autosomal aberrations associated with testicular dysgenesis or
Autosomal aberrations associated with testicular dysgenesis or

... automatic categorization of the GenBank ESTs into a nonredundant set of gene-oriented clusters. Each UniGene cluster contains sequences that represent a single gene, as well as related information such as the tissue types in which the gene expressed [31]. Although the relationship between certain ch ...
NIH Public Access
NIH Public Access

VCP-RMS-Slide-Set
VCP-RMS-Slide-Set

... − Population studies (identification of a variant in normal, healthy control individuals who do not have a significant family history of cancer) ...
PTC Genes and Bitter Taste
PTC Genes and Bitter Taste

...  Complete the pedigree on the back and answer the questions that go along with it. Website Questions: 1. Who was the scientist that discovered the PTC taste variation among people? ...
Parasites, desiderata lists and the paradox of the organism
Parasites, desiderata lists and the paradox of the organism

... Examine the logic of modern natural selection theory in sexual populations and observe that it is all about changes in frequencies of copies of things. In practice these things are genes, in the sense of Mendelian units independently assorting in gene pools, but any self-replicating entity would do ...
Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a
Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a

... Reactive oxygen generation is well characterized in phagocytes where the respiratory burst oxidase (termed nicotinamide adenine dinucleotide phosphate [NADPH]*-oxidase) catalyzes NADPH-dependent reduction of molecular oxygen to generate superoxide and secondarily metabolites including hydrogen perox ...
Marine integrons containing novel integrase genes
Marine integrons containing novel integrase genes

... cassettes in marine polluted sediments, metagenomic DNAs were extracted from sites at Suez and Tokyo Bays. PCR amplicons containing new integrase genes, intI, linked with novel gene cassettes, were recovered and had sizes from 1.8 to 2.5 kb. This approach uncovered, for the first time, the structure ...
as a PDF
as a PDF

CETT CDG handout for clinicians AKT 4-30-10 17-39-08
CETT CDG handout for clinicians AKT 4-30-10 17-39-08

... biochemically, genetic testing is required to determine the type and subtype of CDG. Because of the wide variety and overlap of symptoms seen in affected individuals, it is very difficult to identify which CDG gene may be responsible for the symptoms in any given patient. While single gene testing i ...
(2013). Nothing in genetics makes sense except in light of genomic
(2013). Nothing in genetics makes sense except in light of genomic

... A -coded hormone), then although A gained a reproductive advantage at the expense of A and B, no genomic conflict occurred—only canonical individual-level selection occurred at each interacting locus leading to their mutualistic coevolution. To illustrate genomic conflict, first suppose that A and B ...
Section 11.3 - Trimble County Schools
Section 11.3 - Trimble County Schools

... To determine if the segregation of one pair of alleles affects the segregation of another pair of alleles, Mendel performed a two-factor cross – dihybrid cross (1) ...
Exploring Prostate Proteins and Antibodies
Exploring Prostate Proteins and Antibodies

... Only 21 Prostate Specific Proteins Of all the genes expressed in prostate, 186 genes show various degrees of elevated expression in prostate compared to other tissues. Only 21 genes were found to be prostate specific (enriched), expressed at least five times more in prostate as compared to other tis ...
Chromosomal Microarray Analysis
Chromosomal Microarray Analysis

... benign (i.e. does not cause disease) • Abnormality detected – A gain or loss of chromosomal material known to result in a defined genetic condition has been detected • Results of uncertain significance – A gain or loss of chromosomal material not known to result in a defined genetic condition has be ...
doc
doc

... gametes were more frequent than the other two kinds that were rare. Moreover, the two common gametic combinations were equally frequent as were the two rare kinds. This pattern of inheritance, in which the alleles of different genes tend to not segregate independently during meiosis, is found to occ ...
Mutation Is Random
Mutation Is Random

... should review the distribution of answers and note whether there are questions in which fewer than 60% of students answered correctly. In addition, the instructor may want to highlight a few questions and show the connection between the question and the text from which the question was developed. It ...
Research Project Final Report
Research Project Final Report

... We have identified, among exotic germplasm, lines with extremely stable green colour, one of which has been used to establish a population of recombinant inbred lines, using a commercial bleach-prone line as the second parent. These lines have been used to make a genetic map that will inform future ...
Current Microbiology
Current Microbiology

... lacZKmR cassette, which carries a termination signal within (Fig. 2). Alternatively, it could be argued that solely hoxY and hoxH are transcribed from an independent weak promoter, and Na2S2O4- and methyl viologendependent H2-evolution requires these two hydrogenase structural genes only. In an atte ...
Lec-GenomeAllignment2010
Lec-GenomeAllignment2010

... genes labeled A,B,C,D, and R. R is a multicopy (repetitive) gene, with different copies labeled using numeric subscripts. Each copy of R is assumed to be identical in sequence, so that orthology/paralogy is unknowable from nucleotide substitution (as is often the case with ...
For those mutants where the enhancement bred true, if
For those mutants where the enhancement bred true, if

... +/ +; Df(3R)p13, e, */ TM6B were selected by the presence of the ebony marker, and the absence of the p[w+] marker, and used to create independent stocks. Those mutants which segregated with the X chromosome were discarded. ...
Nucleotide sequence analysis - Bioinformatics Unit
Nucleotide sequence analysis - Bioinformatics Unit

... •Is it contaminated with vector sequences? •Is it an already known gene? •Is  it  related  to  any  other  genes  either  by  having  a  common ancestor? •Is  it  similar  in  function  to  other  genes  via  convergent  evolution? •What  could  the  protein  sequence  be  for  this  nucleotide  fra ...
Medical Coverage Policy Genetic Testing: Hereditary Breast and/or
Medical Coverage Policy Genetic Testing: Hereditary Breast and/or

... cancer among affected women. These mutations may be gene sequence variations or large rearrangements/deletions. Knowledge of mutation status in individuals at risk of a BRCA mutation may impact healthcare decisions to reduce risk. Risk-reducing options include intensive surveillance, chemoprophylaxi ...
Patterns of prokaryotic lateral gene transfers affecting
Patterns of prokaryotic lateral gene transfers affecting

... ’TMDs ≥ 4’ or ‘TMDs 1-3’ refers to the number of TMDs predicted on protein sequences. Transporters typically have at least four TMDs (TMDs ≥ 4). Proteins with one to three TMDs represent putative membrane proteins. d EC numbers were annotated for each entry based on a significant sequence similarity ...
Mutation status of essential thrombocythemia and primary
Mutation status of essential thrombocythemia and primary

... For the majority of patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF), clinical diagnosis can be aided by mutational findings in JAK2, CALR or MPL. The JAK2 V617F mutation is found in about half of the cases and has been included as a major criterion for diagnosis in the W ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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