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Misregulation of pre-mRNA splicing that causes human diseases
Misregulation of pre-mRNA splicing that causes human diseases

... pre-mRNA processing are integrated processes that can be modified by cellular signals. Several diseases are caused by mutations in sequences that regulate pre-mRNA processing. Their molecular characterization indicates that contributions of pre-mRNA splicing defects to human diseases have been under ...
A Chromosome Assay Method for the Detection of
A Chromosome Assay Method for the Detection of

... The tests for het gene location on linkage group VIII gave four positive results and one negative. It should be noted that this negative result and the previous inconsistent result, obtained with the linkage group I tests, have both involved strain RD6-21. It would seem likely that this strain has e ...
Emerging model systems in evo-devo: cavefish and microevolution
Emerging model systems in evo-devo: cavefish and microevolution

... Microevolution is defined as evolutionary changes of relatively small scale that operate within a single species (Dobzhansky 1951). In recent years, evolutionary developmental biologists have made considerable progress in understanding the molecular basis of developmental changes during evolution. In ...
Identification of Genes Mediating Drosophila Follicle Cell Progenitor
Identification of Genes Mediating Drosophila Follicle Cell Progenitor

... We continued our search for genes needed in two doses for normal follicle progenitor differentiation within the positive deletions on the assumption that one or at most two genes were responsible for the dosage effect of the entire deletion. Thus, for each of the positive deletions we obtained small ...
Recombineering Hunchback identifies two conserved domains
Recombineering Hunchback identifies two conserved domains

... containing amino acids 1641-2149 of the Zfh2 protein [pZFH-2c (Lai et al., 1991)], and purified proteins were sent to Alpha Diagnostic International (San Antonia, TX, USA) for injection into rats. Primary antibodies used were: rat Zfh2, 1:400 (this work; M. Lundell, UT San Antonio, USA); mouse Eve 2 ...
Genetics Review Problems
Genetics Review Problems

... P = purple, pp = white. The offspring of a cross between two heterozygous purple-flowering plants (Pp Pp) results in a. all purple-flowered plants. b. purple-flowered plants and white-flowered plants. c. two types of white-flowered plants: PP and Pp. d. all white-flowered plants. e. all pink-flowere ...
in Graminaceous Plants
in Graminaceous Plants

... more efficiently than the binding fraction (Table II). Therefore, we assumed that this fraction contained another NAAT isozyme and named it NAAT-III. In the NA-affinity chromatography step, the specific activity of NAAT-III was increased more efficiently when using NA to elute the protein rather tha ...
Stringent Response in Myxococcus xanthus
Stringent Response in Myxococcus xanthus

... Fruiting body formation Starve for amino acids Accumulation of (p)ppGpp Accumulate (p)ppGpp ??Starve for aa Fruiting bodies Is this a causal relationship? Is there a connection between initiation of fruiting body development and (p)ppGpp accumulation? ...
114KB - NZQA
114KB - NZQA

... Dominance: is the interaction between alleles of one gene. One dominant allele is expressed over a second recessive allele at the same locus. Co-dominance: A allele and the B allele are equal in their dominance and will be expressed equally if they are paired together into the genotype IA IB. Neithe ...
P site - Industrial ISD
P site - Industrial ISD

... pair of complimentary nucleotides with another nucleotide pair is called a base-pair substitution. • Some base-pair substitutions have little or no impact on protein function. • In silent mutations, alterations of nucleotides still indicate the same amino acids because of redundancy in the genetic c ...
Microsoft Word Document
Microsoft Word Document

... Allele- A unique form of a given gene. For example, the wild-type copy of a gene is one allele and a mutant copy of the same gene is also an allele of that gene. Allele is a genetic term used to describe the form of the gene present in the cells. ...
Bio.B.2- Genetics
Bio.B.2- Genetics

... • Produced by self-pollination of F1 plants – Always saw the same results (parental trait reappears) in a specific ratio ...
VegT initiates endoderm formation
VegT initiates endoderm formation

... in each LightCycler run. Undiluted control cDNA=100%, 1:1 cDNA:H2O=50% and 1:10 cDNA:H2O=10% (shown only in Fig. 1). In experiments where multiple embryonic stages were examined, the dilution series was used from cDNA of the uninjected control stage of development predicted to give the highest expre ...
1 Glossary 5` overhang- Restriction enzymes that cleave the DNA
1 Glossary 5` overhang- Restriction enzymes that cleave the DNA

... Allele- A unique form of a given gene. For example, the wild-type copy of a gene is one allele and a mutant copy of the same gene is also an allele of that gene. Allele is a genetic term used to describe the form of the gene present in the cells. ...
Genomic overview of serine proteases
Genomic overview of serine proteases

... ends of each of these clusters did not reveal any sequence similarity to serine proteases. We also mapped the four serine proteases that form a cluster on chromosome 14q11.2–q11.3 and found that all genes are transcribed from telomere to centromere. Genes of this cluster are generally smaller (2.7–3 ...
Punnett Squares and Binomials
Punnett Squares and Binomials

... Motivational questions: 1. Why do we resemble one parent more than they other? 2. Why is there sometimes a mix of looking like both parents? Phase of Inquiry: Punnett squares are diagrams that are used to show the possible ways that genes can combine at fertilization. In a Punnett square, dominant g ...
Constitutional Mismatch Repair Deficiency Syndrome
Constitutional Mismatch Repair Deficiency Syndrome

... A child with constitutional mismatch repair deficiency syndrome can develop more than one type of cancer at a time or more than one cancer during the person’s lifetime. What causes constitutional mismatch repair deficiency syndrome? Constitutional mismatch repair deficiency syndrome is related to ch ...
2.5.1 Variation of Species 2.5.2 Heredity and Gene
2.5.1 Variation of Species 2.5.2 Heredity and Gene

... 2.5.4 DNA Structure, Replication and Profiling Follow-Me – iQuiz ...
The Differential Killing of Genes by Inversions in Prokaryotic Genomes
The Differential Killing of Genes by Inversions in Prokaryotic Genomes

... strand is located on the leading strand, it is assumed that “the gene lies on the leading strand.” In prokaryotic genomes, the leading and lagging roles of DNA strands are predetermined by location of the origin of replication and the terminus of replication. Thus, a gene stays at the same position ...
Answer Key
Answer Key

... 1. Selective breeding. Farmers choose the best animals to breed with each other by looking at the traits that they considered favourable (for example, the fastest or those which produced the most milk). 2. Ways to produce these traits should relate to finding parent animals with the same traits. Stu ...
Proposed alignment of helical interruptions in the two subunits of the
Proposed alignment of helical interruptions in the two subunits of the

... and 8, Ala is substituted for Gly. Either one of these substitutions will not affect the physical parameters of the collagen molecule substantially (Mao, B. and Vogeli, G., unpublished data from computer modelling). It is, however, also possible that the cyz (IV) chain was the ancestral gene with ma ...
Product Fact Sheet
Product Fact Sheet

... Multiple-ChoiceTM First-Strand cDNA Kits are formatted for the rapid and efficient screening of a panel of tissues for gene expression. The cDNA panels provided in these kits are also ideal for the characterization of alternatively spliced mRNA either within a single tissue or across multiple organi ...
preimplantation genetic diagnosis (pgd): application of the
preimplantation genetic diagnosis (pgd): application of the

... embryos both free of the disease and of a compatible Human Leukocyte Antigen (HLA) tissue type with an existing affected child. Stem cells from the resulting baby’s umbilical cord blood could be used in the treatment of the affected sibling, that without stem cell transplant is likely to die. The ma ...
Pedigrees - Holy Trinity Academy
Pedigrees - Holy Trinity Academy

PcGs and Hox genes - Development
PcGs and Hox genes - Development

... characterized, the molecular basis of heritable Hox gene silencing is poorly understood. Silencing appears to involve the acquisition of some kind of mark by Hox genes that are initially repressed. This mark, sometimes referred to as a cellular memory, both confers transcriptional repression and is ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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