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Nonsensemediated decay of glutathione peroxidase 1 mRNA in the
Nonsensemediated decay of glutathione peroxidase 1 mRNA in the

... site, i.e. 105 bp downstream of the codons (Figure 1; data not shown for TGA), and the cellular site of NMD remained cytoplasmic (data not shown). Therefore, GPx1 mRNA is not an exception to the rule for termination codon position within intron-containing genes, which states that nonsense codons loc ...
Team Application Activity #3: Statistical Analysis of Microbial
Team Application Activity #3: Statistical Analysis of Microbial

... evolutionarily, the more closely related their DNA sequences will be. This underlying assumption does have some flaws that need to be kept in mind. As you have already learned, horizontal gene transfer between species can make two species look more (or less) related than they truly are. Also, not al ...
Hemoglobin
Hemoglobin

... RBCs of heterozygotes contain both HB S (a2bs2 ) & HB A (a2b2 ) ...
Patterns of Inheritance Understanding the Chromosome A History of
Patterns of Inheritance Understanding the Chromosome A History of

... 3. Traits are segregated from each other during meiosis. - Mendel’s Law of Segregation: two alleles of a gene segregate or separate from one another during meiosis. - Each gamete produced receives only one allele. - When the sperm fertilizes the egg, the offspring receives one allele from its mother ...
MEDICAL BIOLOGY
MEDICAL BIOLOGY

... gametes". Cytological basis of the laws. Analysing crossing, its practical importance. Lethal genes. Deviation from the expected segregation. Di- and polyhybrid crossing: law of independent combining of characters, its cytologic meaning. Dominant and recessive types of inheritance of the normal and ...
Host-pathogen interactions in drosophila: new tricks from an old friend
Host-pathogen interactions in drosophila: new tricks from an old friend

... NATURE IMMUNOLOGY VOLUME 7 NUMBER 9 SEPTEMBER 2006 ...
Supplementary Figure Legends (doc 52K)
Supplementary Figure Legends (doc 52K)

... profiles of bacterial PCR products from separated (a) [13C]-phenanthrene fractions aligned to equivalent [12C]-phenanthrene fractions, (b) [13C]naphthalene fractions aligned to equivalent [12C]-naphthalene fractions, and (c) [13C]-hexadecane fractions aligned to equivalent [12C]hexadecane fractions, ...
Drug Development Slides - Genomics, Bioinformatics & Medicine
Drug Development Slides - Genomics, Bioinformatics & Medicine

Chapter 5
Chapter 5

Document
Document

... the regulation of gene expression and observed differences between individuals in a a population • 3.25 THS can create a visual representation to illustrate how changes in a DNA nucelotide sequence can result in a change in the polypeptide produced. ...
Insertion (sufB) in the anticodon loop or base substitution (sufC) in
Insertion (sufB) in the anticodon loop or base substitution (sufC) in

... been shown to occur in both eubacteria and eukaryotes (1). Shifts • To whom correspondence should be addressed ...
Etude Annotation
Etude Annotation

... As  you  mouse  over  the  Frames  window,  the  lower  left  box  will  display  in  real-­‐time  the  base   pair  coordinate  of  your  cursor.   My  screen  isn’t  quite  big  enough  to  comfortably  display  both  the  frame   ...
Identification of One BOCR Mutation and Five NF1 Mutations in Male
Identification of One BOCR Mutation and Five NF1 Mutations in Male

... San Diego, CA, USA) was performed to generate paired-end reads (90 bp at each end). The sequenced reads were aligned to the human genome reference (UCSC hg19) using Burrows-Wheeler Alignment (BWA) software [25]. Duplicate read removal, format conversion, and indexing were performed with Picard. The ...
A B - Drug Metabolism and Disposition
A B - Drug Metabolism and Disposition

(COX2) gene in giant panda, Ailuropoda melanoleuca
(COX2) gene in giant panda, Ailuropoda melanoleuca

... has a unique bamboo-based diet; however, this low-energy intake has been sufficient to maintain the metabolic processes of this species since the fourth ice age. As mitochondria are the main sites for energy metabolism in animals, the protein-coding genes involved in mitochondrial respiratory chains ...
Network properties of human disease genes with pleiotropic effects
Network properties of human disease genes with pleiotropic effects

... inter-modular hubs with the former being highly co-expressed with their interactors contrary to the latter. Essential genes were predominantly nuclear proteins with transcriptional regulation activities while phenodiv genes were cytoplasmic proteins involved in signal transduction. Conclusion: The p ...
Linkage Introduction
Linkage Introduction

... When loci are physically located close to one another on a chromosome, there is a deviation from this relationship. This deviation is summarized by the recombination fraction. The recombination fraction is often denoted by θ where ...
slides
slides

... Endogenous retroviruses Microsatellite repeats ...
Article Old but Not (So) Degenerated—Slow
Article Old but Not (So) Degenerated—Slow

... (group 1:34.8–35.4 Mb; group 2:36.7–40.1 Mb; group 3:40.9– 52.4 Mb), these groups differ significantly in dS (analysis of variance, F = 32.63, P = 0.0006), with a significant difference between group 1 and group 2 (P = 0.006, Tukey’s post-hoc test) and between group 1 and group 3 (P = 0.0005). Altho ...
Package `LDheatmap`
Package `LDheatmap`

... The input object gdat can be a data frame of genotype objects (a data structure from the genetics package), a snp.matrix object (a data structure from the chopsticks package), or any square matrix with values between 0 and 1 inclusive. LD computation is much faster for snp.matrix objects than for ge ...
Slides
Slides

... §Caused by radiation, ROS, DNA damaging agents, or as result of replication errors §Repaired by two mechanisms: non-homologous end joining (NHEJ) and homologous recombination §NHEJ is error prone because there is no requirement for sequence homology §Recombination will be explained next ...
Promoter Analysis of the Mouse Sterol Regulatory Element
Promoter Analysis of the Mouse Sterol Regulatory Element

... The SRE containing promoters analyzed to date in sterol-regulated genes contain NF-Y or Sp1 sites adjacent to SREs, and these cofactors were shown to be indispensable for sterol regulation (32, 34 –37). The initial deletion study suggests that the components of the SRE complex are crucial for both b ...
alleles and punnett square notesBLANK
alleles and punnett square notesBLANK

in Graminaceous Plants
in Graminaceous Plants

... more efficiently than the binding fraction (Table II). Therefore, we assumed that this fraction contained another NAAT isozyme and named it NAAT-III. In the NA-affinity chromatography step, the specific activity of NAAT-III was increased more efficiently when using NA to elute the protein rather tha ...
Genetics Review Problems
Genetics Review Problems

... P = purple, pp = white. The offspring of a cross between two heterozygous purple-flowering plants (Pp Pp) results in a. all purple-flowered plants. b. purple-flowered plants and white-flowered plants. c. two types of white-flowered plants: PP and Pp. d. all white-flowered plants. e. all pink-flowere ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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