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Pengaturan Ekspresi gen 1. Struktur gen prokaryot dan eukaryot
Pengaturan Ekspresi gen 1. Struktur gen prokaryot dan eukaryot

... alone (sometimes referred to as the primary transcript) would contain both coding (exon) and noncoding (intron) sequences. Before it can be translated into protein, the two ends of the RNA are modified, the introns are removed by an enzymatically catalyzed RNA splicing reaction, and the resulting mR ...
Gene Section GAS5 (growth arrest specific 5 (non protein
Gene Section GAS5 (growth arrest specific 5 (non protein

... GAS5 is encoded at 1q25, a locus displaying abnormalities in a number of cancers, e.g. melanoma, prostate, breast, and several types of leukaemia and lymphoma. Gene expression analysis has shown that GAS5 is up-regulated 3.3-fold (the greatest upregulation for any gene in the whole-genome array) by ...
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... Quiz#1 LC710 ...
Literature two-hybrid systems
Literature two-hybrid systems

... • Even 20 to 10 tags might not be statistically significant given the large numbers of comparisons • Often, 10-fold over- or under-expression is taken as threshold ...
One Gene- One Enzyme Theory 2016 EHSS 920KB Feb 17
One Gene- One Enzyme Theory 2016 EHSS 920KB Feb 17

... The genetic code is a set of rules for determining how genetic information in the form of a nucleotide sequence is converted to an amino acid sequence of a protein. Researchers identified four nucleotides in RNA (A, U, G, and C) and 20 amino acids. Mathematically, there could not be a one-toone rela ...
Chapter 17 - Denton ISD
Chapter 17 - Denton ISD

... the RNA from the degradation. RNA is spliced by a ____________ made of snRNA, removing noncoding sections called _______, and leaving exons. Some genes can produce multiple polypeptides depending on what is spliced; this is called ___________________. Exon shuffling during cross-over may also be use ...
Microarray Data Analysis Day 2
Microarray Data Analysis Day 2

PowerPoint プレゼンテーション
PowerPoint プレゼンテーション

... technique in the field of targeted genome engineering, editing and reverse genetics. Its applications span from introducing knockout mutations to endogenous tagging of proteins and targeted excision repair. Owing to this wide range of possible applications, there is a need for fast and user-friendly ...
Transcription
Transcription

... initially synthesized‐‐a cut‐and‐paste job called RNA splicing. The average length of a transcription unit along a eukaryotic DNA  molecule is about 8,000 nucleotides, so the primary RNA transcript is also that long. But it takes only about 1,200 nucleotides to  code for an average‐sized protein of  ...
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Document

... • Utilization of expression profiles for study of biological mechanisms, disease mechanisms • Application of DNA arrays in chromatin immuno precipitation – gene regulation ...
Chapter 16
Chapter 16

... • Toes are short, which make humans great long distance runners • Short toes are great for push off during running (toes are for balance too) • The pinky toes – are not used for running…so it may be possible that people may start being born without them… ...
Quick Lab - mattesmagic
Quick Lab - mattesmagic

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Principles of Genetics, A BRIEF INTRODUCTION
Principles of Genetics, A BRIEF INTRODUCTION

... There is a repair mechanism however not all of the sequences can be repaired. So genes can have: ...
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...  IT and Analysis Tool  Storage and analysis (1000 microarrays for billions of data points) ...
LecCh6Annotation
LecCh6Annotation

... Noncoding RNA (ncRNA) • ncRNA represent 98% of all transcripts in a mammalian cell • ncRNA have not been taken into account in gene counts • cDNA • ORF computational prediction • Comparative genomics looking at ORF ...
GENETICS
GENETICS

... suppressor gene so that it does not work anymore, uncontrolled cell growth could result ...
Checklist unit 18: Regulation of Gene Expression
Checklist unit 18: Regulation of Gene Expression

... organization in developing embryos. In completely developed organisms, the regulation of gene expression can allow an individual to maintain homeostasis and react to changes in the environment. In addition, it is becoming apparent that being able to control the turning on and off of genes may lead t ...
Eukaryotic Gene Expression
Eukaryotic Gene Expression

... • DNA methylation; the addition of methyl groups to DNA • essential for inactivation of the DNA – Inactive genes in a cell are methylated – Epigenetic memory due to methylating enzymes that methylate the new daughter strand the same as the parent strand. • Can be passed on in repro ...
From Gene to Protein
From Gene to Protein

... • Genes have instructions for making proteins, but genes do not make proteins directly • Transcription is the synthesis of RNA under the direction of DNA. DNA provides the template. Get an accurate copy; mRNA • Translation is the actual synthesis of a polypeptide, at the ribosome, under the directio ...
Todd Eckdahl - Davidson College
Todd Eckdahl - Davidson College

... cDNA and hybridization  Reverse transcription of RNA  capture sequence incorporated ...
No Slide Title
No Slide Title

... Transfer RNA (tRNA) leaves the nucleus, binds to the amino acid specified by it’s anticodon and transfers it to the ribisome where it meets up with mRNA to assemble a protein. ...
Hox Genes
Hox Genes

... ...
Control of Gene Express in Prokaryotes
Control of Gene Express in Prokaryotes

... • Regulation of enzyme activityfeedback inhibition • Regulation of gene expression ...
Chapter 10B: Gene Expression
Chapter 10B: Gene Expression

... • when we talk about “genes” we will focus on those that express proteins ( the “end products” for a small percentage of genes are special types of RNA molecules) ...
Institute of Genetics and Molecular and Cellular Biology
Institute of Genetics and Molecular and Cellular Biology

... We are searching for a highly motivated and career-oriented research fellow with a high level of independence a PhD degree in molecular and cellular biology. Candidates must have a solid experience in chromatin biology, systems biology and cancer research. Possessing programming skills and experienc ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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