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biochemistry - Angelo State University
biochemistry - Angelo State University

... Catalysts are substances that increase the rate of chemical rxs without themselves becoming chemically changed or part of the product. Molecules called enzymes are biological catalysts. The presence of enzymes is the single most important factor determining the rate of chemical rxs in living systems ...
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Abiogenesis



Abiogenesis (Brit.: /ˌeɪbaɪ.ɵˈdʒɛnɨsɪs/ AY-by-oh-JEN-ə-siss U.S. English pronunciation: /ˌeɪˌbaɪoʊˈdʒɛnᵻsɪs/), or biopoiesis, is the natural process of life arising from non-living matter, such as simple organic compounds. It is thought to have occurred on Earth between 3.8 and 4 billion years ago, and is studied through a combination of laboratory experiments and extrapolation from the genetic information of modern organisms in order to make reasonable conjectures about what pre-life chemical reactions may have given rise to a living system.The study of abiogenesis involves three main types of considerations: the geophysical, the chemical, and the biological, with more recent approaches attempting a synthesis of all three. Many approaches investigate how self-replicating molecules, or their components, came into existence. It is generally accepted that current life on Earth descended from an RNA world, although RNA-based life may not have been the first life to have existed. The Miller–Urey experiment and similar experiments demonstrated that most amino acids, basic chemicals of life, can be synthesized from inorganic compounds in conditions intended to be similar to early Earth. Several mechanisms have been investigated, including lightning and radiation. Other approaches (""metabolism first"" hypotheses) focus on understanding how catalysis in chemical systems in the early Earth might have provided the precursor molecules necessary for self-replication. Complex organic molecules have been found in the Solar System and in interstellar space, and these molecules may have provided starting material for the development of life on Earth.According to the panspermia hypothesis, microscopic life—distributed by meteoroids, asteroids and other small Solar System bodies—may exist throughout the Universe. It is speculated that the biochemistry of life may have begun shortly after the Big Bang, 13.8 billion years ago, during a habitable epoch when the age of the universe was only 10–17 million years.Nonetheless, Earth is the only place in the Universe known to harbor life. The age of the Earth is about 4.54 billion years. The earliest undisputed evidence of life on Earth dates at least from 3.5 billion years ago, during the Eoarchean Era after a geological crust started to solidify following the earlier molten Hadean Eon. There are microbial mat fossils found in 3.48 billion-year-old sandstone discovered in Western Australia. Other early physical evidence of a biogenic substance is graphite in 3.7 billion-year-old metasedimentary rocks discovered in southwestern Greenland.
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