end of semester main examination - UR-CST
... c. transfer methyl groups. d. transfer groups to and from amino acids. e. are involved in carboxylation or decarboxylation reactions. ii. Outline the role of Metal ion cofactors in the enzyme catalyzed reactions. (5 marks) iii. List the four general ways in which enzymes are controlled. (4 marks) iv ...
... c. transfer methyl groups. d. transfer groups to and from amino acids. e. are involved in carboxylation or decarboxylation reactions. ii. Outline the role of Metal ion cofactors in the enzyme catalyzed reactions. (5 marks) iii. List the four general ways in which enzymes are controlled. (4 marks) iv ...
Coma - ENLS Protocols
... and exposure to nonpharmacologic neurotoxic compounds. Treatment is guided by the underlying etiology. Where appropriate, specific antagonists/antidotes should be administered. For example: Opioid overdose: naloxone Acetaminophen overdose: N-acetylcysteine In selected cases, such as acute live ...
... and exposure to nonpharmacologic neurotoxic compounds. Treatment is guided by the underlying etiology. Where appropriate, specific antagonists/antidotes should be administered. For example: Opioid overdose: naloxone Acetaminophen overdose: N-acetylcysteine In selected cases, such as acute live ...
metabolic adaptations to six-month caloric restriction
... pigment that accumulates with age in non-dividing cells such as neurons and muscle 42. Isoprostanes are prostaglandin-like products of arachidonic acid peroxidation that have been putatively shown to be associated with oxidative stress 43. However, most attention has been paid to the effects of ROS ...
... pigment that accumulates with age in non-dividing cells such as neurons and muscle 42. Isoprostanes are prostaglandin-like products of arachidonic acid peroxidation that have been putatively shown to be associated with oxidative stress 43. However, most attention has been paid to the effects of ROS ...
Exploring Chemistry Using SMT - Theoretical Biochemistry Group
... problem. The problem can be rephrased for chemical reaction systems in the following way: finding a set of compatible molecules that react according to a reaction mechanism which was translated from an abstract mathematical prototype model. Of course the solution of this inverse problem is usually n ...
... problem. The problem can be rephrased for chemical reaction systems in the following way: finding a set of compatible molecules that react according to a reaction mechanism which was translated from an abstract mathematical prototype model. Of course the solution of this inverse problem is usually n ...
Dinazyme C/S
... Involves movement of electrons from one molecule to another. In biological systems we usually see the removal of hydrogen from the substrate. Enzymes in this class are called dehydrogenases. Ex., alcohol dehydrogen-ase catalyzes reactions of the type R-CH2OH + A → R-CHO + H2A, where A is an acceptor ...
... Involves movement of electrons from one molecule to another. In biological systems we usually see the removal of hydrogen from the substrate. Enzymes in this class are called dehydrogenases. Ex., alcohol dehydrogen-ase catalyzes reactions of the type R-CH2OH + A → R-CHO + H2A, where A is an acceptor ...
Protein damage on Cu2+
... MCO reactions during IMAC: Presence of hydroxyl radicals – An MCO reaction which includes the Fenton Reaction gives rise to oxidizing species such as OH radical in the reaction between the metal and the peroxide. – The presence of OH radicals indicates that a Fenton reaction (or some other radical g ...
... MCO reactions during IMAC: Presence of hydroxyl radicals – An MCO reaction which includes the Fenton Reaction gives rise to oxidizing species such as OH radical in the reaction between the metal and the peroxide. – The presence of OH radicals indicates that a Fenton reaction (or some other radical g ...
NAD + , NADP +
... absorption of niacin is much reduced, and whose caloric needs are often met with distilled spirits that are virtually devoid of vitamins, including niacin. ...
... absorption of niacin is much reduced, and whose caloric needs are often met with distilled spirits that are virtually devoid of vitamins, including niacin. ...
1 Comp. Funct. Genom. Copyright © (2002) John Wiley & Sons, Ltd.
... genes and proteins based on shared biology. It will also aid the interpretation of large datasets created by functional genomics projects [6]. The majority of eukaryotic genome projects already use the GO annotation system, and GO annotations are being incorporated into SWISSPROT and GeneDB (see sec ...
... genes and proteins based on shared biology. It will also aid the interpretation of large datasets created by functional genomics projects [6]. The majority of eukaryotic genome projects already use the GO annotation system, and GO annotations are being incorporated into SWISSPROT and GeneDB (see sec ...
Metabolic fuels: regulating fluxes to select mix
... evidence is summarized in Fig.3. Subsequent morphometric analyses of locomotory muscles in dogs and goats have characterized differences in the spatial arrangement of mitochondria and capillaries between the two species (Vock et al., 1996a; Vock et al., 1996b). They reveal that maximal rates of cir ...
... evidence is summarized in Fig.3. Subsequent morphometric analyses of locomotory muscles in dogs and goats have characterized differences in the spatial arrangement of mitochondria and capillaries between the two species (Vock et al., 1996a; Vock et al., 1996b). They reveal that maximal rates of cir ...
Powerpoint template for scientific poster
... cells has led to a revived interest in the useful biological activity, highly complex structure and intriguing biosynthetic mechanisms of these compounds for further application purposes. ...
... cells has led to a revived interest in the useful biological activity, highly complex structure and intriguing biosynthetic mechanisms of these compounds for further application purposes. ...
LABORATORY MANUAL ON BIOLOGICAL CHEMISTRY
... Biological chemistry is a fundamental medical discipline. A competence in biochemical processes, which take place on different levels of organization – cellular, organ, tissues and in a whole body – is necessary to medical students for understanding of metabolic processes and turnover of substances ...
... Biological chemistry is a fundamental medical discipline. A competence in biochemical processes, which take place on different levels of organization – cellular, organ, tissues and in a whole body – is necessary to medical students for understanding of metabolic processes and turnover of substances ...
AMINO ACID BIOSYNTHESIS
... TRANSAMINATED TO PHENYLPYRUVATE, SHOWING STRUCTURES EXPLAIN WHY CHILDREN WITH A TETRAHYDROBIOPTERIN DEFICIENCY EXCRETE LARGE AMOUNTS OF PHE WHY DO PEOPLE WITH PKU HAVE BLOND HAIR, ...
... TRANSAMINATED TO PHENYLPYRUVATE, SHOWING STRUCTURES EXPLAIN WHY CHILDREN WITH A TETRAHYDROBIOPTERIN DEFICIENCY EXCRETE LARGE AMOUNTS OF PHE WHY DO PEOPLE WITH PKU HAVE BLOND HAIR, ...
Energetics at the Molecular Level Energetics: Scientific Foundations of Obesity and Other Health Aspects Douglas R Moellering, Ph.D.
... through glycolysis is inhibited at PFK when the cell contains ample stores of ATP and oxidizable substrates. Additionally, PFK is activated by AMP and ADP because they indicate low levels of ATP in the cell. F2,6BP is the major activator, though, because it reciprocally inhibits fructose 1,6 bisphos ...
... through glycolysis is inhibited at PFK when the cell contains ample stores of ATP and oxidizable substrates. Additionally, PFK is activated by AMP and ADP because they indicate low levels of ATP in the cell. F2,6BP is the major activator, though, because it reciprocally inhibits fructose 1,6 bisphos ...
A Study of the Effects of Exercise on the Urinary Metabolome
... From the smell and colour of urine as a tool for disease diagnosis [1] to the elusive promise of an “exercise pill” as a preventative measure of disease [2,3], could this be the future of health prescription? How could exercise, with its multi-factorial and multi-organ health benefits [2,4–7], be su ...
... From the smell and colour of urine as a tool for disease diagnosis [1] to the elusive promise of an “exercise pill” as a preventative measure of disease [2,3], could this be the future of health prescription? How could exercise, with its multi-factorial and multi-organ health benefits [2,4–7], be su ...
Theoretical Approaches to the Evolutionary Optimization of Glycolysis
... stated that the target of its design optimization was the maximization of flux and the minimization of transition time. If the same principle can be applied here, then the flux to be maximized is the flux of ATP production and the minimization of the response time to achieve its steady state. Howeve ...
... stated that the target of its design optimization was the maximization of flux and the minimization of transition time. If the same principle can be applied here, then the flux to be maximized is the flux of ATP production and the minimization of the response time to achieve its steady state. Howeve ...
Transcriptome profiling identifies candidate genes associated with
... Common bean (Phaseolus vulgaris ) and black gram (Vigna mungo ) accumulate γ-glutamylS -methylcysteine and γ-glutamyl-methionine in seed, respectively. Transcripts were profiled by 454 pyrosequencing data at a similar developmental stage coinciding with the beginning of the accumulation of these met ...
... Common bean (Phaseolus vulgaris ) and black gram (Vigna mungo ) accumulate γ-glutamylS -methylcysteine and γ-glutamyl-methionine in seed, respectively. Transcripts were profiled by 454 pyrosequencing data at a similar developmental stage coinciding with the beginning of the accumulation of these met ...
Protocol S1.
... media, Lrp (a transcription factor that is highly expressed in minimal media) had no inferred targets. Most of the known Lrp targets had a weak, incorrect correlation to LexA (Figure S6a inset), but these correlations were correctly eliminated by CLR. Only when the arrays from minimal media were com ...
... media, Lrp (a transcription factor that is highly expressed in minimal media) had no inferred targets. Most of the known Lrp targets had a weak, incorrect correlation to LexA (Figure S6a inset), but these correlations were correctly eliminated by CLR. Only when the arrays from minimal media were com ...
Metabolic and physicochemical ch. in inflamm... 85KB 06.09.2016
... 39Co, the pain in mamma became worse. Objectively: a dense formation with unclear edges is felt in the sick breast; its sizes are 5×5 cm, is sharply painful during palpation. There are no sites of softening and fluctuation. Redness of the skin, dilation of subcutaneous venous vessels in the site of ...
... 39Co, the pain in mamma became worse. Objectively: a dense formation with unclear edges is felt in the sick breast; its sizes are 5×5 cm, is sharply painful during palpation. There are no sites of softening and fluctuation. Redness of the skin, dilation of subcutaneous venous vessels in the site of ...
Dusty Carroll Lesson Plan 4
... formation of dimers, then dimerization of the dimers to form the tetramer. (7) Each domain has a hydrophobic core, consistent with the notion that the monomers formed individually before joining. Some of the domains then interact with each other through polar networks on their exterior surfaces. The ...
... formation of dimers, then dimerization of the dimers to form the tetramer. (7) Each domain has a hydrophobic core, consistent with the notion that the monomers formed individually before joining. Some of the domains then interact with each other through polar networks on their exterior surfaces. The ...
Metabolic network modelling
Metabolic network reconstruction and simulation allows for an in-depth insight into the molecular mechanisms of a particular organism. In particular, these models correlate the genome with molecular physiology. A reconstruction breaks down metabolic pathways (such as glycolysis and the Citric acid cycle) into their respective reactions and enzymes, and analyzes them within the perspective of the entire network. In simplified terms, a reconstruction collects all of the relevant metabolic information of an organism and compiles it in a mathematical model. Validation and analysis of reconstructions can allow identification of key features of metabolism such as growth yield, resource distribution, network robustness, and gene essentiality. This knowledge can then be applied to create novel biotechnology.In general, the process to build a reconstruction is as follows: Draft a reconstruction Refine the model Convert model into a mathematical/computational representation Evaluate and debug model through experimentation↑