Immunology Notes
... lining cellos of the upper and lower respiratory tracts and the gastrointestinal and genitourinary organs perform a scavenger function, clearing the body of insoluble and unneeded debris. Serve as first line of defense against microorganisms, entrapping and killing these foreign invaders ...
... lining cellos of the upper and lower respiratory tracts and the gastrointestinal and genitourinary organs perform a scavenger function, clearing the body of insoluble and unneeded debris. Serve as first line of defense against microorganisms, entrapping and killing these foreign invaders ...
Porgador COBRE seminar 082813 (PDF)
... The matter of the pathogen- and tumor-associated ligands recognized by the NCRs has been a subject of intense research ever since their identification more than a decade ago. Expression patterns recognized by NCRs include pathogen-derived, pathogen-induced and tumor-associated cellular "self" ligand ...
... The matter of the pathogen- and tumor-associated ligands recognized by the NCRs has been a subject of intense research ever since their identification more than a decade ago. Expression patterns recognized by NCRs include pathogen-derived, pathogen-induced and tumor-associated cellular "self" ligand ...
11.2
... Macrophages Develop from monocytes Eat foreign bacteria (phagocytosis) Found all over body ...
... Macrophages Develop from monocytes Eat foreign bacteria (phagocytosis) Found all over body ...
Chapter 17: IR to Infectious Disease
... Chapter 17: IR to Infectious Disease • In BIOL 304, we examined how pathogens can establish an infection in a susceptible host • Re: the 7 components of pathogenicity!! • On the other hand, humans are defended by: ...
... Chapter 17: IR to Infectious Disease • In BIOL 304, we examined how pathogens can establish an infection in a susceptible host • Re: the 7 components of pathogenicity!! • On the other hand, humans are defended by: ...
Time course of immune response
... • Inhibitory signal= – KIR/lectin molecules recognize MHC class I ...
... • Inhibitory signal= – KIR/lectin molecules recognize MHC class I ...
Immune System Summmary
... flow of blood. However, the deadly tetanus bacterium, Clostridium tetani has already entered the wound and has imbedded in the tissues and blood. The immune system can recognize the bacterium as an invader (non-self) because it displays different surface antigens from your own cells. The bacterium m ...
... flow of blood. However, the deadly tetanus bacterium, Clostridium tetani has already entered the wound and has imbedded in the tissues and blood. The immune system can recognize the bacterium as an invader (non-self) because it displays different surface antigens from your own cells. The bacterium m ...
Immune system
... appendix, Peyer patches in the intestine) - filter lymph and capture present antigens MALT (mucous associated lymphoid tissue) diffuse lymphatic tissue, the main role is capture of antigens passing through the mucosal epithelium ...
... appendix, Peyer patches in the intestine) - filter lymph and capture present antigens MALT (mucous associated lymphoid tissue) diffuse lymphatic tissue, the main role is capture of antigens passing through the mucosal epithelium ...
The integrated view
... transforms primary follicle into secondary follicle. Mature B-cells differentiate into plasma cells that migrate to medulla (to be away from Ag stimulating the response) Plasma cells secrete a single type of Ag-specific Ab into efferent fluids. ...
... transforms primary follicle into secondary follicle. Mature B-cells differentiate into plasma cells that migrate to medulla (to be away from Ag stimulating the response) Plasma cells secrete a single type of Ag-specific Ab into efferent fluids. ...
Organs of the Immune System 01/31/06
... Secondary follicle (Germinal center) is site of B cell proliferation, mutation, differentiation Specificity is high >90% of B cells die through apoptosis After Ag stimualtion lymphocyte numbers up by 50X in efferent lymphatic vessel Lympadenopathy ...
... Secondary follicle (Germinal center) is site of B cell proliferation, mutation, differentiation Specificity is high >90% of B cells die through apoptosis After Ag stimualtion lymphocyte numbers up by 50X in efferent lymphatic vessel Lympadenopathy ...
Topic 19 - Roslyn Public Schools
... • 3. Hydrochloric acid – destroys some of the pathogens that enter the digestive system ...
... • 3. Hydrochloric acid – destroys some of the pathogens that enter the digestive system ...
40 -2 THE IMMUNE SYSTEM
... 3. Immune Response – A series of specific defenses designed to attack a particular pathogen. Antigen – A foreign protein ID) that triggers an immune response. Lymphocytes – WBCs in body that recognize and destroy antigens. B Cells & T Cells are produced in bone marrow. B cells mature in Bone marrow ...
... 3. Immune Response – A series of specific defenses designed to attack a particular pathogen. Antigen – A foreign protein ID) that triggers an immune response. Lymphocytes – WBCs in body that recognize and destroy antigens. B Cells & T Cells are produced in bone marrow. B cells mature in Bone marrow ...
Slide 1 - scome911
... – Monocytes /Macrophages – Neutrophils – Mast cells – Eosinophils – Basophils ...
... – Monocytes /Macrophages – Neutrophils – Mast cells – Eosinophils – Basophils ...
Type of Innate immune
... Several types of molecules play vital roles in immune responses. Antibodies are substances which provoke an immune response. Antibodies are not only the surface receptors of B cells that recognize specific antigens, but once the appropriate B cells are activated and differentiate into plasma cells; ...
... Several types of molecules play vital roles in immune responses. Antibodies are substances which provoke an immune response. Antibodies are not only the surface receptors of B cells that recognize specific antigens, but once the appropriate B cells are activated and differentiate into plasma cells; ...
Document
... 4. Collectins recognize a variety of bacteria, yeast, and some viruses. They grab onto them and hook them up together so that they can be easily phagocytized. D. Fever - Infection causes lymphocytes to make interleukin-1 that causes the body’s temperature set point to increase. This causes the live ...
... 4. Collectins recognize a variety of bacteria, yeast, and some viruses. They grab onto them and hook them up together so that they can be easily phagocytized. D. Fever - Infection causes lymphocytes to make interleukin-1 that causes the body’s temperature set point to increase. This causes the live ...
Immunity - Misericordia University
... • Individual targets are selected for attack by the lymphocytes that can bind that target (antigen) • Antigens (Ag) – any large substance not normally found in the body; these illicit an immune response (immunogenic and immuno-reactive) • Haptens are small molecules that can trigger an immune respon ...
... • Individual targets are selected for attack by the lymphocytes that can bind that target (antigen) • Antigens (Ag) – any large substance not normally found in the body; these illicit an immune response (immunogenic and immuno-reactive) • Haptens are small molecules that can trigger an immune respon ...
National Research Program
... Melody is investigating how the immune system clears away cancer cells to identify ways to help improve this process in transplant patients. Her aim is to reduce GVHD and its associated immune-deficiency while promoting the immune system’s clearance of leukaemia. “The white blood cells that kill res ...
... Melody is investigating how the immune system clears away cancer cells to identify ways to help improve this process in transplant patients. Her aim is to reduce GVHD and its associated immune-deficiency while promoting the immune system’s clearance of leukaemia. “The white blood cells that kill res ...
Immune response part 1
... •Digest pathogen – harmless products removed (egested / excreted) or used by phagocyte •Phagocyte also displays antigenic components on external surface of plasma cell ...
... •Digest pathogen – harmless products removed (egested / excreted) or used by phagocyte •Phagocyte also displays antigenic components on external surface of plasma cell ...
Phagocyte
Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.