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Humoral Immunity
Humoral Immunity

... specific immune response. • A group of cells called Antigen presenting cells (APC) activate the acquired immune system. • Macrophages, Dendritic cells and B-cells are ...
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...  macrophages can also serve as APC  tested by Helper T cells ...
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... • They do not require thymus for maturation ...
The Immune System - Harvard Life Science Outreach Program
The Immune System - Harvard Life Science Outreach Program

...  & attached to the cell’s MHC when processed through the cell’s machinery  MHC-antigen complex is placed on the cell ...
Stress and the Immune Response
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... epinephrine, growth hormone, and prolactin ...
19 Physiology of leukocytes
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... are called pathogenic. Inside the body the micro-organism has ideal conditions of food, water and temperature, so flourish. Immunity is the body’s ability to resist infection by a disease-causing organism (pathogen) or to destroy it after invasion. Immunity can be innate or acquired. ...
Respiratory tract
Respiratory tract

... differentiate to plasma cells and synthetise molecules of immunoglobulins - T cells – origin from bone marrow, then touched by thymus leave it to enter circulation - NK cells – different from T and B cells – large non phagocyting granular leucocytes. Killing abnormal ( infected or cancer) host cells ...
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... Immune system is probably evolved to deal with infections, to rid the body of infectious agents, and to prevent reinfection. Pathogens that it cannot get rid of are trouble. ...
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White Blood Cells

... Natural killer cells: Natural killer cells are able to kill cells of the body which are displaying a signal to kill them, as they have been infected by a virus or ...
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... response to certain pathogens. • An antigen is any substance that triggers an immune response. • The immune system carries out immune responses to antigens • Self-tolerance is when a body does not attack its own tissues and chemicals. Lack of self tolerance results in autoimmune diseases. ...
The Lymphatic/Immune System
The Lymphatic/Immune System

... Examples of non-specific= specific resistance (genetic by species resistance to certain diseases) medical and chemical barriers (secretion, skin, mucus, sebum, hydrochloric acid, enzymes), phagocytosis (phagocytes ingest and destroy foreign microorganisms), inflammation (tissue damage brings in medi ...
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... Activation can induce expression. Cell adhesion, migration, antigen specificity, antigen presentation, costimulation, helper function, effector function. Cell surface molecules influenced by activation include cytokine receptors. ...
Biology: Infectious Diseases
Biology: Infectious Diseases

... myelin sheath that protects the nerve fibers. There is some evidence that suggests that a viral infection can trigger this disease. In 1957, scientists discovered that virus-infected cells produce a protein called interferon that helps other cells resist viral infections and block viral replication. ...
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... activates complement system IgA- in exocrine gland secretions IgM- in plasma; activates complement system IgD- found on surfaces of B cells; activates B cells IgE- in exocrine gland secretions; associated with allergic reaction ...
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43.3 Active and Passive immunity Active Immunity Passive Immunity

Immune System A
Immune System A

... encounter antigens they may later attack Are exported to secondary lymphoid tissue where encounters with antigens occur Mature into fully functional antigen-activated cells upon binding with their recognized antigen It is genes, not antigens, that determine which foreign substances our immune system ...
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APSpring14_142Q2Aans..

... Active artificially acquired immunity Passive artificially acquired immunity A&C ...
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immune system - immunology.unideb.hu

... Few pathogens and macrophages Weak response, few lymphocytes Many pathogens and macrophages ...
Immunity
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... Everyone's immune system is different. Some people never seem to get infections, whereas others seem to be sick all the time. As people get older, they usually become immune to more germs as the immune system comes into contact with more and more of them. That's why adults and teens tend to get fewe ...
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The Immune System - Town of Mansfield, CT
The Immune System - Town of Mansfield, CT

... proteins) that cover every single cell in our body. When the special immune cells of the immune system travel in our body, they check if all antigens are “ours”. Some antigens are foreign to our body, which makes the special cells of the immune system proceed to an immune response. ...
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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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