Thymus-Therapie in Practice
... humoral systems to combat micro-organisms, parasites and viruses. The ability to do this is particularly important in the removal of cells that have degenerated within the body and become “foreign”. The first cancer cells to develop should be destroyed by the immune response. A sufficient number of ...
... humoral systems to combat micro-organisms, parasites and viruses. The ability to do this is particularly important in the removal of cells that have degenerated within the body and become “foreign”. The first cancer cells to develop should be destroyed by the immune response. A sufficient number of ...
Mice exposed to dim light at night exaggerate inflammatory
... 24 h post-LPS injection. Overall, these data suggest that chronic exposure to even very low levels of light pollution may alter inflammatory responses. These results may have important implications for humans and other urban dwelling species that commonly experience nighttime light exposure. Ó 2013 E ...
... 24 h post-LPS injection. Overall, these data suggest that chronic exposure to even very low levels of light pollution may alter inflammatory responses. These results may have important implications for humans and other urban dwelling species that commonly experience nighttime light exposure. Ó 2013 E ...
Nieuwste middelen
... spleen/lymph node cells with SP2/0 MM cells) Testing of 42 anti-CD38 mAbs in CDC assays only one mAb was capable to induce CDC this antibody was selected for further testing=daratumumab VU University Medical Center Amsterdam The Netherlands ...
... spleen/lymph node cells with SP2/0 MM cells) Testing of 42 anti-CD38 mAbs in CDC assays only one mAb was capable to induce CDC this antibody was selected for further testing=daratumumab VU University Medical Center Amsterdam The Netherlands ...
Here - European Macrophage and Dendritic Cell Society
... democracy and dogma-free scientific research and they have recently joined forces to offer multilingual course programmes under the name “Brussels University Alliance”. It is therefore not that surprising that we have chosen an auditorium on the ULB Solbosch campus as scientific venue for the EMDS m ...
... democracy and dogma-free scientific research and they have recently joined forces to offer multilingual course programmes under the name “Brussels University Alliance”. It is therefore not that surprising that we have chosen an auditorium on the ULB Solbosch campus as scientific venue for the EMDS m ...
Activation of the Inflammatory Response by Fungal
... and adaptive immunity. Their purpose is to protect the body from disease-causing microorganisms, physical stress or tissue damage. The innate immune system is the first to be activated; it facilitates the direct elimination of pathogens as well as initiating the inflammatory response. It also provid ...
... and adaptive immunity. Their purpose is to protect the body from disease-causing microorganisms, physical stress or tissue damage. The innate immune system is the first to be activated; it facilitates the direct elimination of pathogens as well as initiating the inflammatory response. It also provid ...
Influence of sex steroids on inflammation and bone metabolism
... nuclear receptors that up- or down-regulate gene expression by binding to the hormone response elements of target genes. In addition, steroid modulation of transcription factors also serves to regulate patterns of gene expression (10, 121). The latter (nongenomic) effects of sex steroids involve int ...
... nuclear receptors that up- or down-regulate gene expression by binding to the hormone response elements of target genes. In addition, steroid modulation of transcription factors also serves to regulate patterns of gene expression (10, 121). The latter (nongenomic) effects of sex steroids involve int ...
Viruses We Eat
... airways are fair game for infection, even if they are not proliferating. All three viruses are cytolytic, so they leave their host cells dead or dying once they have used them as factories to produce new viruses. The death of infected cells in the respiratory tract and the accompanying inflammation ...
... airways are fair game for infection, even if they are not proliferating. All three viruses are cytolytic, so they leave their host cells dead or dying once they have used them as factories to produce new viruses. The death of infected cells in the respiratory tract and the accompanying inflammation ...
PDF
... therapeutic proteins may also neutralize the biological activity of therapeutic proteins and may result in adverse events not only by inhibiting the efficacy of the therapeutic protein product, but by cross-reacting to an endogenous protein counterpart, if present. Because most of the adverse effect ...
... therapeutic proteins may also neutralize the biological activity of therapeutic proteins and may result in adverse events not only by inhibiting the efficacy of the therapeutic protein product, but by cross-reacting to an endogenous protein counterpart, if present. Because most of the adverse effect ...
The presence of cytotoxic autoantibody to lacrimal gland cells
... these mice develop foci of mononuclear cell infiltration in the lacrimal and salivary glands, which closely resemble the lesions seen in patients with Sjogren's syndrome. We studied the cell-mediated and antibody-mediated immune responses of NZB/W mice to lacrimal gland cells. Lacrimal gland acinar ...
... these mice develop foci of mononuclear cell infiltration in the lacrimal and salivary glands, which closely resemble the lesions seen in patients with Sjogren's syndrome. We studied the cell-mediated and antibody-mediated immune responses of NZB/W mice to lacrimal gland cells. Lacrimal gland acinar ...
DDT objectives (combined)
... Describe the molecules encoded by the major histocompatibility complex and how they contribute to induction of cell-mediated immune responses including the mechanism of antigen processing. Describe the cellular and molecular mechanisms used for activation of T lymphocytes including which receptors, ...
... Describe the molecules encoded by the major histocompatibility complex and how they contribute to induction of cell-mediated immune responses including the mechanism of antigen processing. Describe the cellular and molecular mechanisms used for activation of T lymphocytes including which receptors, ...
Drosophila melanogasteras a model for human intestinal infection
... structure Amenability to reverse genetics owing to availability of whole-genome RNAi libraries, molecular markers and other genetic tools In contrast to mammalian-cell-based drug screenings, Drosophila assays provide the complex cellular composition of a real intestine and opportunity to assess toxi ...
... structure Amenability to reverse genetics owing to availability of whole-genome RNAi libraries, molecular markers and other genetic tools In contrast to mammalian-cell-based drug screenings, Drosophila assays provide the complex cellular composition of a real intestine and opportunity to assess toxi ...
Document
... Although the control of transplantation, autoimmunity, and the other immune responses are the phenotypic consequences of the function of molecules encoded in the Mhc, understanding the Mhc becomes clear if we think of it in molecular and cellular terms. MHC molecules are cell surface receptors that ...
... Although the control of transplantation, autoimmunity, and the other immune responses are the phenotypic consequences of the function of molecules encoded in the Mhc, understanding the Mhc becomes clear if we think of it in molecular and cellular terms. MHC molecules are cell surface receptors that ...
Shizuru et al. Hematopoietic Stem and Progenitor Cells: Clinical and
... and give rise to clonal progeny that continue to differentiate (1). Thus, hematopoietic stem cells (HSC) are multipotent cells that give rise to more HSC and all formed elements in the blood. Progenitor cells are cells that may be multipotent, oligopotent, or unipotent, and they lack significant sel ...
... and give rise to clonal progeny that continue to differentiate (1). Thus, hematopoietic stem cells (HSC) are multipotent cells that give rise to more HSC and all formed elements in the blood. Progenitor cells are cells that may be multipotent, oligopotent, or unipotent, and they lack significant sel ...
Echinacea
... • Molecules such as antibodies (immunoglobulins), which interact directly with antigens • Molecules of the major histocompatibility complex(or MHC), which are expressed on the surface of cells and interact with Tcells as part of the adaptive immune response. ...
... • Molecules such as antibodies (immunoglobulins), which interact directly with antigens • Molecules of the major histocompatibility complex(or MHC), which are expressed on the surface of cells and interact with Tcells as part of the adaptive immune response. ...
Association between Tuberculin Skin Test Reactivity, the Memory
... tuberculin unit TST (RT23; Statens Serum Institute) was placed on the volar aspect of the forearm, and the site was marked with a circle with the use of a felt-tip pen. At 48 h, the transverse diameter of TST induration was determined using the ballpoint pen and ruler method [14]. Administration of ...
... tuberculin unit TST (RT23; Statens Serum Institute) was placed on the volar aspect of the forearm, and the site was marked with a circle with the use of a felt-tip pen. At 48 h, the transverse diameter of TST induration was determined using the ballpoint pen and ruler method [14]. Administration of ...
Immune Response by Chikungunya Virus Triggers an Innate Active
... blood vessels before dissemination to the target tissues/or organs (17). Although the exact route and mechanisms of early infection is poorly defined (18), previous studies from other alphaviruses have indicated the involvement of different immune cell populations in the skin (19–22), and migrating ...
... blood vessels before dissemination to the target tissues/or organs (17). Although the exact route and mechanisms of early infection is poorly defined (18), previous studies from other alphaviruses have indicated the involvement of different immune cell populations in the skin (19–22), and migrating ...
Clinical features and pathobiology of Ebolavirus
... coagulation cascade and production of proinflammatory cytokines by macrophages that leads to shock and multiorgan failure during the terminal phase. ...
... coagulation cascade and production of proinflammatory cytokines by macrophages that leads to shock and multiorgan failure during the terminal phase. ...
Pericytes: brain-immune interface modulators
... secreting chemo-attractant molecules and by modulating immune cell entry into the brain. The majority of published studies on the blood-brain barrier focus on endothelial cells, which are a critical component, but not the only one; other cellular components include astroglia, microglia, and pericyte ...
... secreting chemo-attractant molecules and by modulating immune cell entry into the brain. The majority of published studies on the blood-brain barrier focus on endothelial cells, which are a critical component, but not the only one; other cellular components include astroglia, microglia, and pericyte ...
Olefsky on Ouchi Science
... cytokines which work locally through paracrine mechanisms to cause decreased sensitivity to insulin in nearby adipocytes (6). The macrophages also secrete chemokines that recruit further waves of monocytes into the adipose tissue, creating a feed-forward chronic proinflammatory state. The general out ...
... cytokines which work locally through paracrine mechanisms to cause decreased sensitivity to insulin in nearby adipocytes (6). The macrophages also secrete chemokines that recruit further waves of monocytes into the adipose tissue, creating a feed-forward chronic proinflammatory state. The general out ...
Phagocytes may counteract the “open window” situation during a
... Dale 1988, Brenner et al. 1998). Leukocytosis is generally observed after intense exercise, in which the relationship with stress hormones is more clearly documented. Nevertheless, the profile of release of stress hormones can differ according to the exercise intensity and duration. Thus, during mod ...
... Dale 1988, Brenner et al. 1998). Leukocytosis is generally observed after intense exercise, in which the relationship with stress hormones is more clearly documented. Nevertheless, the profile of release of stress hormones can differ according to the exercise intensity and duration. Thus, during mod ...
Complement in the Brain
... and a local, chronic inflammatory response that leads to attraction and activation of glial cells that, under such activation conditions, can produce neurotoxic substances, including proinflammatory cytokines and oxygen radicals. This process may be exacerbated by a disturbed balance between complem ...
... and a local, chronic inflammatory response that leads to attraction and activation of glial cells that, under such activation conditions, can produce neurotoxic substances, including proinflammatory cytokines and oxygen radicals. This process may be exacerbated by a disturbed balance between complem ...
sistema inmune2
... The body produces many types of lymphocytes: – each fights a different type of antigen – active lymphocyte clones itself to fight specific antigen ...
... The body produces many types of lymphocytes: – each fights a different type of antigen – active lymphocyte clones itself to fight specific antigen ...
Recent progress in vaccines
... outcome, the distinction remains substantial both for vaccine formulation and for establishing correlates/surrogates of protection in clinical trials. In particular, the T cell-based mechanisms mediate protection indirectly, that is, promoting an inflammatory response with recruitment of soluble (an ...
... outcome, the distinction remains substantial both for vaccine formulation and for establishing correlates/surrogates of protection in clinical trials. In particular, the T cell-based mechanisms mediate protection indirectly, that is, promoting an inflammatory response with recruitment of soluble (an ...
When parasitic wasps hijacked viruses
... host quality before oviposition or to feed on the host. This behaviour may have favoured encounters with viruses, which can themselves use the wasps as vectors for horizontal transmission, as is the case for ascoviruses [51,52]. It should be noted that pathogenic virus infection induced during ovipo ...
... host quality before oviposition or to feed on the host. This behaviour may have favoured encounters with viruses, which can themselves use the wasps as vectors for horizontal transmission, as is the case for ascoviruses [51,52]. It should be noted that pathogenic virus infection induced during ovipo ...