IMMUNOMODULATORY ACTIVITY OF ALCOHOLIC EXTRACT OF HABENARIA INTERMEDIA IN MICE Research Article
... In view of the pivotal role played by the macrophages in coordinating the processing and presentation of antigen to β-cells. Phagocytic index [Table 4] were (P<0.05) significantly increased as compared to control and Cyclophosphamide group. Hence, increased clearance rate of carbon particles from ci ...
... In view of the pivotal role played by the macrophages in coordinating the processing and presentation of antigen to β-cells. Phagocytic index [Table 4] were (P<0.05) significantly increased as compared to control and Cyclophosphamide group. Hence, increased clearance rate of carbon particles from ci ...
Adjuvant Autologous Tumour Cell
... different but yet unknown antigens compared to benign renal cells and the fact that RCC in general demonstrates a reduced expression of HLA molecules (Gansbacher et al., 1990; Boon et al., 1994). Principally, a tumour cell lysate vaccine stimulates antigen-presenting cells including dendritic cells. ...
... different but yet unknown antigens compared to benign renal cells and the fact that RCC in general demonstrates a reduced expression of HLA molecules (Gansbacher et al., 1990; Boon et al., 1994). Principally, a tumour cell lysate vaccine stimulates antigen-presenting cells including dendritic cells. ...
Lymphodepletion followed by donor lymphocyte
... lymphopenia on CD8⫹ T-cell homeostatic expansion. NK cells did not increase at any time point (data not shown). T-cell proliferation, as measured by expression of the Ki67 marker (a nuclear protein associated with proliferation), increased significantly in recipients 14 days after DLI (10.3% ⫾ 2.8%) ...
... lymphopenia on CD8⫹ T-cell homeostatic expansion. NK cells did not increase at any time point (data not shown). T-cell proliferation, as measured by expression of the Ki67 marker (a nuclear protein associated with proliferation), increased significantly in recipients 14 days after DLI (10.3% ⫾ 2.8%) ...
Basophils: new players in the cytokine network
... Like all other blood leukocytes, basophils and mast cells, derive from the common hematopoietic pluripotent stem cell in the bone marrow. They complete their maturation in the bone marrow before entering the bloodstream, conversely to mast cells that leave this site at a precursor stage to different ...
... Like all other blood leukocytes, basophils and mast cells, derive from the common hematopoietic pluripotent stem cell in the bone marrow. They complete their maturation in the bone marrow before entering the bloodstream, conversely to mast cells that leave this site at a precursor stage to different ...
Structural, functional and molecular analysis of the effects of aging in
... immune system [1,2]. The colon is also host to a broad variety of microorganisms that not only are responsible for the fermentation of undigested nutrients and the synthesis of essential vitamins, but also play a crucial role in the establishment of a proper immune system in postnatal life [1]. Rece ...
... immune system [1,2]. The colon is also host to a broad variety of microorganisms that not only are responsible for the fermentation of undigested nutrients and the synthesis of essential vitamins, but also play a crucial role in the establishment of a proper immune system in postnatal life [1]. Rece ...
Asthma and pulmonary arterial hypertension: pathogenesis? PERSPECTIVE
... attributable to NFAT activation: asthma and PAH (fig. 2). 2) Replacement therapy with VIP reverses both phenotypes. 3) The therapeutic effect of VIP in VIP-/- mice duplicates that of the VIVIT peptide [49], a selective calcineurin/NFAT pathway inhibitor. 4) These findings suggest that lack of the VI ...
... attributable to NFAT activation: asthma and PAH (fig. 2). 2) Replacement therapy with VIP reverses both phenotypes. 3) The therapeutic effect of VIP in VIP-/- mice duplicates that of the VIVIT peptide [49], a selective calcineurin/NFAT pathway inhibitor. 4) These findings suggest that lack of the VI ...
Methylation - The Hoffman Centre for Integrative Medicine
... cells respond by healing themselves and thus restoring their optimal function. When cells function optimally, then tissues function properly. When tissues function optimally, then organs and ...
... cells respond by healing themselves and thus restoring their optimal function. When cells function optimally, then tissues function properly. When tissues function optimally, then organs and ...
Natural regulatory T cells in infectious disease - Direct-MS
... response to them often results in tissue damage. This tissue damage might be more intense were it not for many regulatory mechanisms that contain the ‘zeal’ of both innate and adaptive effector responses. The once-disfavored idea that suppressor cells with antigen specificity form part of the regula ...
... response to them often results in tissue damage. This tissue damage might be more intense were it not for many regulatory mechanisms that contain the ‘zeal’ of both innate and adaptive effector responses. The once-disfavored idea that suppressor cells with antigen specificity form part of the regula ...
Aloe Vera and the Human Immune System
... immuneslstemin a majorway. The mostobviousof theseis allergles.On the faceof it the last thing which the immunesystemmight appearto needin suchcasesis stimulatio4 becausethe trouble appearsto arisefrom an over-stimulatedconditionof the immune ...
... immuneslstemin a majorway. The mostobviousof theseis allergles.On the faceof it the last thing which the immunesystemmight appearto needin suchcasesis stimulatio4 becausethe trouble appearsto arisefrom an over-stimulatedconditionof the immune ...
4/5/99
... controlling the viral set point. The mechanism of viral inhibition by these cells is likely mediated through CTL, which are able to lyse infected cells before progeny virions are produced (Yang, Kalams et al. 1996). In the acutely treated patients, we have now detected strong HIV-1 specific T helpe ...
... controlling the viral set point. The mechanism of viral inhibition by these cells is likely mediated through CTL, which are able to lyse infected cells before progeny virions are produced (Yang, Kalams et al. 1996). In the acutely treated patients, we have now detected strong HIV-1 specific T helpe ...
HIV persistence in the testis?
... Predicted to protect immunogenic spermatids from immune responses and inflammation ...
... Predicted to protect immunogenic spermatids from immune responses and inflammation ...
Vitamin D and tuberculosis
... this effect, the researchers1 conducted a cohort study among 78 patients with confirmed pulmonary TB (positive sputum test and TB symptoms). Kaplan-Meier survival analysis for the total treatment-time follow-up period showed that patients with the VDR FokI FF genotype had significantly faster conversio ...
... this effect, the researchers1 conducted a cohort study among 78 patients with confirmed pulmonary TB (positive sputum test and TB symptoms). Kaplan-Meier survival analysis for the total treatment-time follow-up period showed that patients with the VDR FokI FF genotype had significantly faster conversio ...
Diabetes mellitus An Inborn Error of Metabolism ?
... • Heterozygous mutations of the transcription factor HNF1 (HNF1 homeobox B) gene have been associated with a form of MODY5, which is characterized by dominantly inherited diabetes mellitus with renal cysts • This has been described in one child with PNDM and some small renal cysts whilst the other ...
... • Heterozygous mutations of the transcription factor HNF1 (HNF1 homeobox B) gene have been associated with a form of MODY5, which is characterized by dominantly inherited diabetes mellitus with renal cysts • This has been described in one child with PNDM and some small renal cysts whilst the other ...
Antiviral Protection Cell Cross-Presentation, CTL Responses, and
... DC, inducing expression of costimulatory molecules and cytokines, which together with MHC-Ag complexes induce cognate T cells to differentiate into Ag-specific CTL and Th cells (8–11). DC recognize pathogen-associated molecular patterns (PAMPs) and many adjuvants using receptors of the innate immune ...
... DC, inducing expression of costimulatory molecules and cytokines, which together with MHC-Ag complexes induce cognate T cells to differentiate into Ag-specific CTL and Th cells (8–11). DC recognize pathogen-associated molecular patterns (PAMPs) and many adjuvants using receptors of the innate immune ...
The Effects of Atrazine on Tail Regeneration in
... Over the past decade the issue of declining amphibian populations has been in the forefront of both scientific and popular literature. Amphibians are important environmental indicators because they have thin moist skin, which is used as a respiratory surface, and because they lay their eggs in the w ...
... Over the past decade the issue of declining amphibian populations has been in the forefront of both scientific and popular literature. Amphibians are important environmental indicators because they have thin moist skin, which is used as a respiratory surface, and because they lay their eggs in the w ...
Predictive value of inflammatory Cytokines in preeclampsia
... cell adhesion on the endothelium with resultant vascular damage. It is also stated that proinflammatory cytokines associated with the genesis of PE (i.e., tumor necrosis factor-α and interleukin-1) enhanced IL-6 mRNA levels and increased secreted IL-6 levels in first trimester leukocyte free decidua ...
... cell adhesion on the endothelium with resultant vascular damage. It is also stated that proinflammatory cytokines associated with the genesis of PE (i.e., tumor necrosis factor-α and interleukin-1) enhanced IL-6 mRNA levels and increased secreted IL-6 levels in first trimester leukocyte free decidua ...
Antiviral applications of Toll-like receptor agonists
... ferrets and possibly involving cytokine release triggered by imiquimod,36 although later studies with more potent non-emetic agents would appear to call this hypothesis into question (see the 8-Hydroxyadenine derivatives section below). Other compounds from the imidazoquinoline series include resiqu ...
... ferrets and possibly involving cytokine release triggered by imiquimod,36 although later studies with more potent non-emetic agents would appear to call this hypothesis into question (see the 8-Hydroxyadenine derivatives section below). Other compounds from the imidazoquinoline series include resiqu ...
In vivo antigen challenge in celiac disease identifies a - Direct-MS
... ‘stepwise’ analysis, with screening of peptides followed by synthesis of further peptides, which produced an increasingly deFig. 1 Amino-acid sequence of A-gliadin A-gliadin 57-73 Q65E is the dominant epitope (bold); sequences identified as bioactive in other studies are underlined. tailed descripti ...
... ‘stepwise’ analysis, with screening of peptides followed by synthesis of further peptides, which produced an increasingly deFig. 1 Amino-acid sequence of A-gliadin A-gliadin 57-73 Q65E is the dominant epitope (bold); sequences identified as bioactive in other studies are underlined. tailed descripti ...
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES
... lysozymes and other secreted substances; cell-mediated responses involve a wide number of cell types, including phagocytes (neutrophils, monocytes/macrophages, and dendritic cells), natural killer cells (NK cells), basophils, mast cells and eosinophils. In the adaptive or specific immune system, hum ...
... lysozymes and other secreted substances; cell-mediated responses involve a wide number of cell types, including phagocytes (neutrophils, monocytes/macrophages, and dendritic cells), natural killer cells (NK cells), basophils, mast cells and eosinophils. In the adaptive or specific immune system, hum ...
World J Gastroenterol
... As a critical element of cellular activity, iron plays a pivotal role in the fight for survival between mammalian hosts and their pathogens, each displaying a wide range of mechanisms for controlling iron acquisition and utilization. Micro-organisms have developed a large number of strategies to acq ...
... As a critical element of cellular activity, iron plays a pivotal role in the fight for survival between mammalian hosts and their pathogens, each displaying a wide range of mechanisms for controlling iron acquisition and utilization. Micro-organisms have developed a large number of strategies to acq ...
Nonspecific Defenses
... were ready to fight off any invaders that managed to get through the outer defenses. Like a medieval castle, the immune system has a series of defenses. In fact, it has three lines of defense. Only pathogens that are able to get through all three lines of defense can harm the body. ...
... were ready to fight off any invaders that managed to get through the outer defenses. Like a medieval castle, the immune system has a series of defenses. In fact, it has three lines of defense. Only pathogens that are able to get through all three lines of defense can harm the body. ...
The immune system is responsible for vigilance against these
... The immune system is responsible for vigilance against these chronic virus, fungi, yeast, and parasitic infections, as well as neoplasms and aging. Bone marrow extracts have been used clinically in a variety of ways involving some of these conditions. They have been used orally and as injectables; b ...
... The immune system is responsible for vigilance against these chronic virus, fungi, yeast, and parasitic infections, as well as neoplasms and aging. Bone marrow extracts have been used clinically in a variety of ways involving some of these conditions. They have been used orally and as injectables; b ...
Candida
... alarmins produced by vaginal epithelial cells in response to Candida. Based on the putative role for the Th17 response in mucosal candidiasis as well as S100 alarmin induction, this study aimed to determine whether the Th17 pathway plays a role in the S100 alarmin-mediated acute inflammation during ...
... alarmins produced by vaginal epithelial cells in response to Candida. Based on the putative role for the Th17 response in mucosal candidiasis as well as S100 alarmin induction, this study aimed to determine whether the Th17 pathway plays a role in the S100 alarmin-mediated acute inflammation during ...