KIDNEY DAMAGE IN AUTOIMMUNE DISEASES
... Summary: Renal involvement in autoimmunity has many facets. Glomerular, tubular and vascular structures are targeted and damaged as a consequence of autoimmune processes. Immunologically mediated kidney diseases represent the third most common cause of end-stage renal failure (after diabetic and hyp ...
... Summary: Renal involvement in autoimmunity has many facets. Glomerular, tubular and vascular structures are targeted and damaged as a consequence of autoimmune processes. Immunologically mediated kidney diseases represent the third most common cause of end-stage renal failure (after diabetic and hyp ...
Immunoinformatics - UWI St. Augustine
... Molecular modeling facility at Bioinformatics centre, University of Pune Serum Institute of India ...
... Molecular modeling facility at Bioinformatics centre, University of Pune Serum Institute of India ...
Activation of cytokines corroborate with development of
... antibodies and (ii) a cellular immune response, where CD8+ T cells with cytotoxic and macrophages are activated. CD4+ lymphocytes participate in both responses by antigen recognition and their subsequent differentiation into effector T helper type 1 (Th1) or Th2 subsets. Th1 cells facilitate the cyt ...
... antibodies and (ii) a cellular immune response, where CD8+ T cells with cytotoxic and macrophages are activated. CD4+ lymphocytes participate in both responses by antigen recognition and their subsequent differentiation into effector T helper type 1 (Th1) or Th2 subsets. Th1 cells facilitate the cyt ...
Temporal patterns in immunity, infection load and disease
... (R. cascadae), we did not examine survival statistically. We logtransformed infection load (q-PCR) data and compared log genome equivalents amongst time-points within each species with a one-way ANOVA. We examined differences in infection load between the two species with two sample t-tests for each ...
... (R. cascadae), we did not examine survival statistically. We logtransformed infection load (q-PCR) data and compared log genome equivalents amongst time-points within each species with a one-way ANOVA. We examined differences in infection load between the two species with two sample t-tests for each ...
BIOL 105 QZ 6 QA NS SS ES LS 130510.3
... The primary cells of the lymphoid system which are vital to the body's ability to resist or overcome infection and disease. A. Macrophages B. Erythrocytes C. Leukocytes D. Lymphocytes ...
... The primary cells of the lymphoid system which are vital to the body's ability to resist or overcome infection and disease. A. Macrophages B. Erythrocytes C. Leukocytes D. Lymphocytes ...
Optimizing Hidden Markov models using Genetic Algorithms and
... HMM parameters. In this paper, the performance of two global optimization techniques is compared with Baum Welch algorithm which is one of the traditional techniques that are used to estimate HMM parameters. These techniques are Genetic Algorithms and Clonal Selection Algorithm which is inspired fro ...
... HMM parameters. In this paper, the performance of two global optimization techniques is compared with Baum Welch algorithm which is one of the traditional techniques that are used to estimate HMM parameters. These techniques are Genetic Algorithms and Clonal Selection Algorithm which is inspired fro ...
Pollen-Induced Oxidative Stress Influences Both Innate and
... maturation, and consequently induce adaptive immune responses. Recently, it has been shown that pollen grains and their allergenic extracts have a potent pro-oxidant activity, which induces profound oxidative stress in the lung or conjunctiva within minutes after exposure (3–5). Inhibition of this i ...
... maturation, and consequently induce adaptive immune responses. Recently, it has been shown that pollen grains and their allergenic extracts have a potent pro-oxidant activity, which induces profound oxidative stress in the lung or conjunctiva within minutes after exposure (3–5). Inhibition of this i ...
lecture-4-radioimmunassay
... • Despite these drawbacks, RIA has become a major tool in the clinical laboratory where it is used to assay • plasma levels of: – most of our hormones; – digitoxin or digoxin in patients receiving these drugs; ...
... • Despite these drawbacks, RIA has become a major tool in the clinical laboratory where it is used to assay • plasma levels of: – most of our hormones; – digitoxin or digoxin in patients receiving these drugs; ...
probiotics – identification and ways of action
... spontaneous and chemically induced colitis by down-regulating inflammatory cytokines or inducing regulatory mechanisms in a strain-specific manner. In animal models of allergen sensitization and murine models of asthma and allergic rhinitis, orally administered probiotics can strain-dependently decr ...
... spontaneous and chemically induced colitis by down-regulating inflammatory cytokines or inducing regulatory mechanisms in a strain-specific manner. In animal models of allergen sensitization and murine models of asthma and allergic rhinitis, orally administered probiotics can strain-dependently decr ...
Modulation of interferon gamma response
... cytokines such as IL-1β, IL-6, TNF-α, IFN-γ [15], as well as anti-inflammatory components, such as IL-1ra, sIL1RII and sCD14 [16,17]. Immune interferon or macrophage activating factor, IFN-γ is the only Type II interferon, which has antiviral, immunoregulatory and antitumour properties [18]. In the ...
... cytokines such as IL-1β, IL-6, TNF-α, IFN-γ [15], as well as anti-inflammatory components, such as IL-1ra, sIL1RII and sCD14 [16,17]. Immune interferon or macrophage activating factor, IFN-γ is the only Type II interferon, which has antiviral, immunoregulatory and antitumour properties [18]. In the ...
Pinto, A. K., A. M. Jamieson, D. H. Raulet, and A. B. Hill. 2007. The role of NKG2D signaling in inhibition of cytotoxic T-lymphocyte lysis by the Murine cytomegalovirus immunoevasin m152/gp40. J. Viro 81:12564-12571 .
... was described by using in vitro CTL lines. To confirm that NKG2D expression was maintained upon culture, we generated short-term polyclonal CTL lines specific for four epitopes and assessed their NKG2D expression. Figure 1C shows that the majority of cells in these lines continued to express NKG2D. ...
... was described by using in vitro CTL lines. To confirm that NKG2D expression was maintained upon culture, we generated short-term polyclonal CTL lines specific for four epitopes and assessed their NKG2D expression. Figure 1C shows that the majority of cells in these lines continued to express NKG2D. ...
New Approaches for Transplant Patients
... • Be The Match helps transplant centers identify unrelated stem cells (donor or umbilical blood) for their patients in need of a transplant • Survival following an unrelated transplant is similar to a transplant using a family member as a donor • Be The Match has many programs to help you and your f ...
... • Be The Match helps transplant centers identify unrelated stem cells (donor or umbilical blood) for their patients in need of a transplant • Survival following an unrelated transplant is similar to a transplant using a family member as a donor • Be The Match has many programs to help you and your f ...
Tumors as Organs
... expand, they also produce factors that activate myofibroblasts and recruit carcinoma-associated fibroblasts. These mesenchymal cell types, as well as adipocytes, are responsible for many of the tumor-associated changes in the extracellular matrix (ECM). (B) Recruitment of cells of the innate and ada ...
... expand, they also produce factors that activate myofibroblasts and recruit carcinoma-associated fibroblasts. These mesenchymal cell types, as well as adipocytes, are responsible for many of the tumor-associated changes in the extracellular matrix (ECM). (B) Recruitment of cells of the innate and ada ...
B cells from African American lupus patients exhibit an
... Systemic lupus erythematosus (SLE) is a complex systemic disease that can affect multiple organs. Both innate and adaptive immune cells are involved in driving the disease (1). In particular, B cells and autoantibody production are believed to participate in the pathogenesis of SLE. Indeed, SLE is c ...
... Systemic lupus erythematosus (SLE) is a complex systemic disease that can affect multiple organs. Both innate and adaptive immune cells are involved in driving the disease (1). In particular, B cells and autoantibody production are believed to participate in the pathogenesis of SLE. Indeed, SLE is c ...
Non-small-cell lung cancers: a heterogeneous set of diseases
... identified genes that cause synthetic lethality with common oncogenic events, such as KRAS-activating mutations or p53 inactivation, leading to potential new treatment targets, such as TANK-binding kinase 1 (TBK1)32. Similarly, the application of mass spectro metry to metabolomic, proteomic and pho ...
... identified genes that cause synthetic lethality with common oncogenic events, such as KRAS-activating mutations or p53 inactivation, leading to potential new treatment targets, such as TANK-binding kinase 1 (TBK1)32. Similarly, the application of mass spectro metry to metabolomic, proteomic and pho ...
TLR2 and TLR4 expression on CD14++ and CD14+ monocyte
... or altered expression of cytokines and pattern-recognition receptors on monocytes may contribute to the development of the autoimmune type of diabetes mellitus (AD). Aims. We aimed to analyze the counts and proportions of the two main subtypes of monocyte cells, CD14++ and CD14+, and to look for pot ...
... or altered expression of cytokines and pattern-recognition receptors on monocytes may contribute to the development of the autoimmune type of diabetes mellitus (AD). Aims. We aimed to analyze the counts and proportions of the two main subtypes of monocyte cells, CD14++ and CD14+, and to look for pot ...
A Pattern Matching Algorithm for Codon Optimization and CpG Motif
... induction of immune responses to the antigens encoded by the vectors. While certain CpG motifs are immuno-stimulatory (CpG-S), enhancing immune responses when the host is vaccinated, others CpG motifs in a different nucleotide context are immuno-inhibitory or -neutralizing (CpG-N) abrogating antigen ...
... induction of immune responses to the antigens encoded by the vectors. While certain CpG motifs are immuno-stimulatory (CpG-S), enhancing immune responses when the host is vaccinated, others CpG motifs in a different nucleotide context are immuno-inhibitory or -neutralizing (CpG-N) abrogating antigen ...
Bovine mammary gland
... the elevation in phagocytic cells, lymphocytes, immunoglobulins and Lf These changes occur too slowly and their antibacterial action is compromised by other normal events of involution. Treatment of glands at or near drying off with colchicine, endotoxin or the combination of the two compounds resul ...
... the elevation in phagocytic cells, lymphocytes, immunoglobulins and Lf These changes occur too slowly and their antibacterial action is compromised by other normal events of involution. Treatment of glands at or near drying off with colchicine, endotoxin or the combination of the two compounds resul ...
Psoriasis and Stress–Psoriasis Aspect of Psychoneuroendocrinology
... neuroendocrine response to systemic and local stress. 3.2 HPA axis-CRH (homeostatic balance) CRH, synthesized in the PVN of the hypothalamus, represents the main driving force controlling HPA axis activation, the major hormone system responsible to maintain homeostatic balance in response to stressf ...
... neuroendocrine response to systemic and local stress. 3.2 HPA axis-CRH (homeostatic balance) CRH, synthesized in the PVN of the hypothalamus, represents the main driving force controlling HPA axis activation, the major hormone system responsible to maintain homeostatic balance in response to stressf ...
Review Article Mechanisms of action of CD20 antibodies
... mAb, approved by the FDA in 1998, was rituximab (RTX) and since then it has been widely used to treat more than one million patients thus far. The success of RTX has led to a general interest in the mechanism of action of CD20 mAbs. CD20 mAbs can induce tumor killing via various mechanisms, such as ...
... mAb, approved by the FDA in 1998, was rituximab (RTX) and since then it has been widely used to treat more than one million patients thus far. The success of RTX has led to a general interest in the mechanism of action of CD20 mAbs. CD20 mAbs can induce tumor killing via various mechanisms, such as ...
VacA`s Induction of VacA-Containing Vacuoles (VCVs) and Their
... was associated with an almost complete absence of metaplasia in the stomach of H. pylori-infected individuals [11]. To become active, the protoxin is processed at the amino- and carboxyl-terminals, yielding a mature 88-kDa cytotoxin, which is then secreted via a type Va secretion system [7,12]. As V ...
... was associated with an almost complete absence of metaplasia in the stomach of H. pylori-infected individuals [11]. To become active, the protoxin is processed at the amino- and carboxyl-terminals, yielding a mature 88-kDa cytotoxin, which is then secreted via a type Va secretion system [7,12]. As V ...