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Le Mercier I et al, 2013
Le Mercier I et al, 2013

Mapping a Dynamic Innate Immunity Protein Interaction Network
Mapping a Dynamic Innate Immunity Protein Interaction Network

Staphylococcus aureus infection induces protein A–mediated
Staphylococcus aureus infection induces protein A–mediated

... and surface-bound virulence factor that is present on most clinical isolates and has been shown to disrupt the humoral immune response in mice (Falugi et al., 2013). SpA contains four or five immunoglobulin-binding domains capable of binding both the Fc of IgG antibodies (preventing opsonophagocytos ...
Two models of multiple sclerosis: Experimental allergic
Two models of multiple sclerosis: Experimental allergic

... Theiler’s virus is a picornavirus, recently classified involvement of a fourth locus, determining the differamong the subgroup of cardioviruses (Pevear et al., ential susceptibility of the SWR and C57BL/6 strains, 1987), and a natural pathogen for mice (Theiler, 1937). whose chromosomal location is ...
MAJOR CAUSES OF STRESS
MAJOR CAUSES OF STRESS

... of mistakes. • Stress is one of the first contributing factors lead into the rest causing the effect. • In order to maintain safety in aviation, stress must be managed to avoid an accident. • This is where all of human factor studies and hard work can come into play. • Depending on what particular j ...
Improvement of adoptive T-cell therapy for Cancer
Improvement of adoptive T-cell therapy for Cancer

... The human immune system is a complex system, which can be divided into innate and adaptive immunity. The innate immune system comprises physical and chemical barriers that contain epithelial surfaces, phagocytic cells and blood proteins (complement system and cytokines). It also includes innate leuk ...
Optimizing Intracellular Flow Cytometry
Optimizing Intracellular Flow Cytometry

[PDF]
[PDF]

... Taken together, close relationships were found between the number of RANKL-positive cells and the degree of macrophages and T, B lymphocytes infiltration respectively, suggesting that these leukocytes may be the three most likely sources of RANKL in the periapical bone resorption. However, as a limi ...
Immune Response to Self Nuclear Autoantigen Determines the Fate
Immune Response to Self Nuclear Autoantigen Determines the Fate

... which are a prototype model of human SLE, the pathway of peripheral tolerance to eliminate self-reactive lymphocytes is impaired due to the deficient Fas/Fas ligand system (8). The importance of peripheral tolerance has already been demonstrated using Tg mice in which the extrathymic organs express ...
The Endocrine System - Life Science Academy
The Endocrine System - Life Science Academy

... Located in the brain, the hypothalamus is responsible for certain metabolic processes and activities of the Autonomic Nervous System, such as temperature, hunger, thirst, fatigue, etc. It links the Endocrine System with the Nervous System by using the pituitary gland. ...
The importance of the type I interferon system in autoimmunity
The importance of the type I interferon system in autoimmunity

... increased apoptosis and reduced clearance of apoptotic cells in lupus (16). Recent studies have shown that neutrophils undergoing so called NETosis also have the capacity to provide intererferogenic autoantigens (17), demonstrating that several pathways can lead to pDC activation. In 2003 several re ...
The Role of Nrf2 in Cellular Innate Immune Response to
The Role of Nrf2 in Cellular Innate Immune Response to

... Nuclear factor erythroid derived 2-related factor-2 (Nrf2) is a master transcription regulator of antioxidant and cytoprotective proteins that mediate cellular defense against oxidative and inflammatory stresses. Disruption of cellular stress response by Nrf2 deficiency causes enhanced susceptibilit ...
IgG2 subclass isotype antibody and intrauterine
IgG2 subclass isotype antibody and intrauterine

... Humans have a range of mechanisms for combating infections. The breakdown of the innate immunity barrier by pathogens is followed by confrontation by the adaptive immune system. An adaptive immune response can be classified into humoral and cell-mediated. Humoral immunity involves the detection of s ...
lec 9-17
lec 9-17

... What’s the difference between T cell with MHC I vs. MHC II? MHC I is on all cells of the body. Its function is to present INTRAcellular Ag; common in virus-infected cells. The virus is degraded to particles, which are then is attached to MHC I (a protein made by RER in that cell). It then gets deliv ...
Full-Text PDF
Full-Text PDF

ANATOMY AND PHYSIOLOGY OF THE AUTONOMIC NERVOUS
ANATOMY AND PHYSIOLOGY OF THE AUTONOMIC NERVOUS

... systems have opposing actions in some situations (e.g. control of heart rate, GIT smooth muscle) but not in others (e.g. salivary glands, ciliary muscles). ...
unit plan stage 6 biology
unit plan stage 6 biology

... rocesses such as decay and nitrogen fixation from the atmosphere. Some bacteria are responsible for infectious diseases in plants and animals. Cardiovascular disease-Disease of the heart or circulatory system. Cholesterol- deposits in arteries and faulty heart valves are examples of cardiovascular d ...
Template to create a scientific poster
Template to create a scientific poster

... • It has been noted that “the propensity of MHC II molecules to present themselves as peptides suggests that pII/MHC II complexes are associated with a specific function”, but that “the cause of preferential presentation of allelic MHC II determinants remains puzzling given that gene allelism has no ...
Immune Complex Deposits as a Characteristic Feature of
Immune Complex Deposits as a Characteristic Feature of

... of cases), rheumatoid arthritis (60% of cases). The presence of autoantibodies to fibrillarin in patients' blood is a suitable diagnostic marker for the early stages of autoimmune diseases development (Tormey et al., 2001). In addition, a recent case-control study reported that severely affected scl ...
Jeopardy
Jeopardy

... IgG antibodies inactivate microbes by blocking their attachment to host cells in the binding process known as a. neutralization. b. agglutination. c. antibody-dependent cell-mediated cytotoxicity. d. opsonization. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. ...
[NOTE: if using this form [bracketed] text is guidance
[NOTE: if using this form [bracketed] text is guidance

Chapter 13
Chapter 13

... • ATP converted to cAMP • cAMP promotes a series of reactions leading to cellular changes ...
Major Endocrine Glands - Reading Community Schools
Major Endocrine Glands - Reading Community Schools

... • ATP converted to cAMP • cAMP promotes a series of reactions leading to cellular changes ...
Integrator Networks: Illuminating the Black Box Linking Genotype
Integrator Networks: Illuminating the Black Box Linking Genotype

Did That Brownie Do Its Job? Stress, Eating, and the
Did That Brownie Do Its Job? Stress, Eating, and the

... cascade of hormonal secretions via the HPA axis. This begins with the release of corticotropin-releasing hormone (CRH) from the hypothalamus, which stimulates the release of adrenocorticotropic hormone (ACTH) from the anterior pituitary gland. ACTH then circulates through the bloodstream to the adre ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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