General pathology Introduction : Pathology is a Greek word
... C- Immunology: study primary diseases of immune system, as well as the effects of other diseases on the immune system. D- Microbiology: study infectious diseases. E- Genetics : study genetic disorders Studying of pathology can be divided into two main parts: 1- general pathology: this part focus on ...
... C- Immunology: study primary diseases of immune system, as well as the effects of other diseases on the immune system. D- Microbiology: study infectious diseases. E- Genetics : study genetic disorders Studying of pathology can be divided into two main parts: 1- general pathology: this part focus on ...
skin and immune system
... pancreas are destroyed – Multiple sclerosis – antibodies destroy the functions of the neurons in the brain and spinal cord – Lupus – attacks normal connective tissue, leading to inflammation and pain in the joints – some of the autoimmune diseases may be treated with immune suppressing drugs • Howev ...
... pancreas are destroyed – Multiple sclerosis – antibodies destroy the functions of the neurons in the brain and spinal cord – Lupus – attacks normal connective tissue, leading to inflammation and pain in the joints – some of the autoimmune diseases may be treated with immune suppressing drugs • Howev ...
of virus infection
... – C5a: attracts and activates neutrophils and cause mast cell degranulation (histamine and LTB4) – C3 derivatives: opsonization Proinflammatory cytokines production – TNF, IL-1 (from macrophages): increase adhesive properties – Chemokines: attracts leukocytes – TNF, IL-1, IL-6: induce acute phase re ...
... – C5a: attracts and activates neutrophils and cause mast cell degranulation (histamine and LTB4) – C3 derivatives: opsonization Proinflammatory cytokines production – TNF, IL-1 (from macrophages): increase adhesive properties – Chemokines: attracts leukocytes – TNF, IL-1, IL-6: induce acute phase re ...
Why chemokines?
... – TH1 cells: • Transcription factor T-bet directs both TH1 cell differentiation and CD4+ T cell expression of ...
... – TH1 cells: • Transcription factor T-bet directs both TH1 cell differentiation and CD4+ T cell expression of ...
Hyposplenism
... Causes slower and incomplete adaptive immune response against bacteria Low levels of tuftsin, which stimulates phagocytosis by neutrophils, macrophages, and monocytes Decreased neutrophil and macrophage activity Increased NK cell activity Limited capacity of circulating B-cells to differentiate into ...
... Causes slower and incomplete adaptive immune response against bacteria Low levels of tuftsin, which stimulates phagocytosis by neutrophils, macrophages, and monocytes Decreased neutrophil and macrophage activity Increased NK cell activity Limited capacity of circulating B-cells to differentiate into ...
Chapter 43 - The Immune System
... Antigens are substances that prompt a response from a B or T cell Antigen receptor proteins allow B and T cells to bind to antigens ◦ Specific enough to bind to just one part of one molecule from a particular pathogen ◦ Millions of antigen receptors (AR) are produced, but all AR’s are identical on e ...
... Antigens are substances that prompt a response from a B or T cell Antigen receptor proteins allow B and T cells to bind to antigens ◦ Specific enough to bind to just one part of one molecule from a particular pathogen ◦ Millions of antigen receptors (AR) are produced, but all AR’s are identical on e ...
I. Immunity
... B. Lymphatic System: produces white blood cells and antibodies 1. White blood cells: two types-T cells and B cells 2. Antibody—protein that disables antigens 3. B cells—makes antibodies 4. T cells—helps make antibodies, kills infected cells 5. Memory B cells—used if attacked again by same antigen -D ...
... B. Lymphatic System: produces white blood cells and antibodies 1. White blood cells: two types-T cells and B cells 2. Antibody—protein that disables antigens 3. B cells—makes antibodies 4. T cells—helps make antibodies, kills infected cells 5. Memory B cells—used if attacked again by same antigen -D ...
The Immune System
... • They kill infected body cells (present foreign antigens on major histocompatability complex (MHC) or other cells that don’t belong (like tumors) at the cell membrane • Class I MHCs = on almost all body cells except RBCs. • Class II MHCs= made by dendritic cells, macrophages, & B cells. ...
... • They kill infected body cells (present foreign antigens on major histocompatability complex (MHC) or other cells that don’t belong (like tumors) at the cell membrane • Class I MHCs = on almost all body cells except RBCs. • Class II MHCs= made by dendritic cells, macrophages, & B cells. ...
1 - Intoduction to immunology 2015-16
... A microbial community that inhabits the skin and mucosal membranes of mouth, gut and vagina. Symbiotic, non-pathogenic microbes, living in „peaceful” commensalisms. In this ecosystem, the fittest survive and there is a competition over nutrients with pathogenic organisms. (Bacteria, Fungi, Protozoa, ...
... A microbial community that inhabits the skin and mucosal membranes of mouth, gut and vagina. Symbiotic, non-pathogenic microbes, living in „peaceful” commensalisms. In this ecosystem, the fittest survive and there is a competition over nutrients with pathogenic organisms. (Bacteria, Fungi, Protozoa, ...
spring 2000 exam 3
... a. are growth factors that work on all cells b. are growth factors that work on blood-forming cells c. are used by T killer cells to signal to other cells d. both b and c are correct X. Immunotherapies involving monoclonal antibodies can work by a. marking cells to target them for cell death b. carr ...
... a. are growth factors that work on all cells b. are growth factors that work on blood-forming cells c. are used by T killer cells to signal to other cells d. both b and c are correct X. Immunotherapies involving monoclonal antibodies can work by a. marking cells to target them for cell death b. carr ...
Med Sch lecture Immunology Laboratory SB 2012
... • Key is understanding the clinical significance of antibodies for diseases – • We use clinical sensitivity and specificity Clinical sensitivity = % of patients with given disease who have positive antibody Clinical specificity = % of healthy people who don’t have the antibody ...
... • Key is understanding the clinical significance of antibodies for diseases – • We use clinical sensitivity and specificity Clinical sensitivity = % of patients with given disease who have positive antibody Clinical specificity = % of healthy people who don’t have the antibody ...
Implantation and Inflammation
... – Phagocytose foreign invaders – Aid in inflammatory response Phagocytosis: the cellular process of engulfing solid particles by the cell membrane to form an internal phagosome, which is a food vacuole, or pteroid. The phagosome is usually delivered to the lysosome, an organelle involved in the brea ...
... – Phagocytose foreign invaders – Aid in inflammatory response Phagocytosis: the cellular process of engulfing solid particles by the cell membrane to form an internal phagosome, which is a food vacuole, or pteroid. The phagosome is usually delivered to the lysosome, an organelle involved in the brea ...
Immune Regulation in the Male Genital Tract
... y8 T cell concentration was consistently observed in men with sperm autoimmunity or immunological evidence of a genital tract Chlamydia trachomatis infection. /8 T cells are also present in the genital tracts of male mice where they have been shown to prevent pro-inflammatory immune resonses to sper ...
... y8 T cell concentration was consistently observed in men with sperm autoimmunity or immunological evidence of a genital tract Chlamydia trachomatis infection. /8 T cells are also present in the genital tracts of male mice where they have been shown to prevent pro-inflammatory immune resonses to sper ...
Replicative Senescence
... International Association of Biomedical Gerontology 10th Congress Queens College/Cambridge September 2003 ...
... International Association of Biomedical Gerontology 10th Congress Queens College/Cambridge September 2003 ...
Assessing the Impact of Microgravity on the Innate Immune System
... The overall goal of this project is to examine the impact of microgravity on the cellular interactions between animals and beneficial microbes. Space flight causes numerous changes in the growth, physiology and virulence of animal-associated microbes. However, most studies have focused on pathogenic ...
... The overall goal of this project is to examine the impact of microgravity on the cellular interactions between animals and beneficial microbes. Space flight causes numerous changes in the growth, physiology and virulence of animal-associated microbes. However, most studies have focused on pathogenic ...
Psychoneuroimmunology
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.