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- Journal of Allergy and Clinical Immunology
- Journal of Allergy and Clinical Immunology

... environmental antigens and danger signals (ligands for TLR and other systems of pattern-recognition receptors). They are present in large numbers in the skin and mucosal sites, where pathogen encounter is most likely, and they actively sample exogenous proteins by means of phagocytosis or endocytosi ...
From parasitism to mutualism
From parasitism to mutualism

Parasites and Parasitism (CAMB 549)
Parasites and Parasitism (CAMB 549)

... chemotherapy represents the major strategy for treating and controlling helminth infections. However, lack of drug options and emergence of parasite drug resistance are huge problems, and new drugs are urgently needed. We will explore current anthelmintic drug targets, and prospects for development ...
Celiac Disease, Inflammation and Oxidative Damage: A
Celiac Disease, Inflammation and Oxidative Damage: A

Abstract Browser  - The Journal of Neuroscience
Abstract Browser - The Journal of Neuroscience

10102 chief round keroro [
10102 chief round keroro [

Chapter 2 Antigen
Chapter 2 Antigen

... II. Common antigen and cross reaction 1. Common antigen Different antigens which possess the same or similar epitopes are called common antigen. 2. Mechanism of cross reaction ----Existence of common Ag determinant ...
Progress in the fight against Inflammatory Diseases and Cancer
Progress in the fight against Inflammatory Diseases and Cancer

File
File

... Soma: The cell body with a nucleus and other structures for cellular life. Axon: a long slender tube covered in myelin that carries information from the cell body to the terminal buttons. Terminal Buttons: Structures which produce chemicals called neurotransmitters when excited by the actions potent ...
Renal-CPC-17-y-old
Renal-CPC-17-y-old

... Genetic deficiency in components of the innate immune system, such as complement component 1q (C1q), C4, serum amyloid protein, natural IgM or complement receptor 2 (CR2) leads to increased susceptibility to systemic lupus erythematosus (SLE). Two general hypotheses have been proposed to explain th ...
- Australasian Society for Immunology
- Australasian Society for Immunology

Document
Document

... unconscious and comatose. During deep sleep, all metabolic functions are significantly reduced; during TEM sleep, muscular activities ar inhibited while cerebral activity is similar to that seen in awake individuals. Sleep disorders result in abnormal reaction times, mood swings and behaviors. Awake ...
Evaluating methods to quantify anthropogenic stressors on wild
Evaluating methods to quantify anthropogenic stressors on wild

... techniques have been developed to measure anthropogenic stressors; all have the ultimate goal of determining if a population can coexist with a particular human activity. For example, considerable effort has focused on developing Geographic Information Systems (GIS) that map both human impacts (e.g. ...
Inflammatory Bowel Diseases Intestinal Failure and
Inflammatory Bowel Diseases Intestinal Failure and

... Basic Mechanisms of IBD • National and international collaborations for sample acquisition, analysis of genetic loci across diverse populations, and research on well-characterized patients followed on a longitudinal basis to define genotype-phenotype correlation • Rapid, quantitative, high-throughpu ...
CURRICULUM VITAE - University of Oxford
CURRICULUM VITAE - University of Oxford

... The work of the group is directly informed by clinical observation from patients we see in clinic, and is then translated back to the patients. This is illustrated, for example, by the ILC2 work above, which is being explored through a clinical trial. We aim to understand disease by studying samples ...
Innate immune responses in hepatitis B virus (HBV
Innate immune responses in hepatitis B virus (HBV

... Natural killer cells (NK cells) are the main effector population involved in innate immune responses to viral infections. They exert antiviral activity through direct cytotoxic effect or through the production of immunoregulatory cytokines (IFN-γ, TNF-α, TGF-β, IL-10, etc). They are identified by fl ...
Document
Document

... that antigen is displayed by MHC molecules – Antigen receptors of T cells have dual specificities: 1. for peptide antigen (responsible for specificity of immune response) and 2. for MHC molecules (responsible for MHC restriction) – During maturation in the thymus, T cells whose antigen receptors see ...
Module 1 - BluWiki
Module 1 - BluWiki

...  Well, mucus! It is a viscous fluid secreted by the mucosal cells - so microorganisms get stuck in it  For example, we have the “ciliated epithelium” on the lower respiratory tract, which catches bacteria which is then propelled to the surface by the sweeping action of cilia  What are some exampl ...
Nighttime 4-Phase Fat Burner
Nighttime 4-Phase Fat Burner

Durand and Barlow Chapter 2: An Integrative Approach to
Durand and Barlow Chapter 2: An Integrative Approach to

... – To e-licit or e-voke motion – Action tendency different from affect and mood – Intimately tied with several forms of psychopathology • Components of Emotion – Behavior, physiology, and cognition – Example of fear ...
23. Parasympathetic nervous system
23. Parasympathetic nervous system

... Visceral sensory and autonomic neurons participate in visceral reflex arcs • Many are spinal reflexes such as defecation and micturition reflexes • Some only involve peripheral neurons: spinal cord not involved (not shown)* *e.g. “enteric” nervous system: 3 neuron reflex arcs entirely within the wa ...
Insights Into the Epidemiology of Sexually Transmitted Diseases
Insights Into the Epidemiology of Sexually Transmitted Diseases

... necessary to modulate the extent of collateral tissue damage downregulate T cell-mediated clearance of the parasite. These immune mechanisms may also be at work during syphilis and account for the cyclical nature of syphilis epidemiology.7 Syphilis cycles with a decadenal frequency, likely in part d ...
The testis in immune privilege
The testis in immune privilege

... and together with the Sertoli cells secrete the components of the basal membrane, which encloses the contents of the seminiferous epithelium. The columnar Sertoli cells extend from the basal lamina toward the lumen of the tubules and constitute the main structural element of the seminiferous epithel ...
Gene, environment, microbiome and mucosal immune tolerance in
Gene, environment, microbiome and mucosal immune tolerance in

... of components of the immune system, including immunoglobulins, complement and cells that include neutrophils, macrophages, dendritic cells and T and B cells [15, 18–23]. Intermixed with the mucosal epithelial cells are cells that produce mucus (e.g. goblet cells), cells with endocrine function (e.g. ...
Evasion of innate immunity by parasitic protozoa
Evasion of innate immunity by parasitic protozoa

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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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