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VL 08lecture2008
VL 08lecture2008

...  Recognizes antigens (molecular signatures) specific for each pathogen  Effective against both intra- and extracellular pathogens  Two main components: Humoral immunity - Relies on Antibodies produced by B-lymphocytes - Fights pathogens outside of cells ...
BIOL 256 SI, Molly 4/13/16 Exam 4 Review Distinguish among
BIOL 256 SI, Molly 4/13/16 Exam 4 Review Distinguish among

... 1.) Distinguish among macrophages, neutrophils, mast cells, eosinophils, and natural killer cells. Macrophages – chief phagocytic cells/ wander through body in search of debris/ Kupffer cells Neutrophils – phagocytize microbes Mast cells – bind bacteria and ingest them Eosinophil – weak phagocytic a ...
Cytokine - Chemotaxis Group
Cytokine - Chemotaxis Group

... IL-1 from site of injury to thalamus – regulation of temperature IL-6 from site of injury to liver – acut phase reaction Erythropoetin from kidney to bone marrow – RBC differentiation ...
The Immune System and Disease
The Immune System and Disease

... bacteria. • Oil and sweat glands in the skin produce an acidic environment that kills many bacteria. • Pathogens can also enter your body through your mouth and nose, where mucus and traps them and cilia push pathogens away from your lungs. • Stomach acid and digestive enzymes destroy many pathogens ...
Cytokine - Chemotaxis Group
Cytokine - Chemotaxis Group

... IL-1 from site of injury to thalamus – regulation of temperature IL-6 from site of injury to liver – acut phase reaction Erythropoetin from kidney to bone marrow – RBC differentiation ...
Immunity and How Vaccines Work
Immunity and How Vaccines Work

... Specific Memory and Adaptive Response Specific Memory and Adaptive Response ...
Generation of ligands for the T cell receptor
Generation of ligands for the T cell receptor

... Cells that have experienced specific antigen previously but need to be triggered to differentiate again to become effector cells ...
Immun System/PART 2 The immune adaptive defense system
Immun System/PART 2 The immune adaptive defense system

... together with antibodies, and can bring PMNs to the region (via chemotaxis). The presence of PMNs may be further detrimental to the bacteria. In the classical description of inflammation an area is presented which appears macroscopically red, swollen, hot and painful, and with possible loss of funct ...
Document
Document

... other enzymes or chemicals. Virus-infected cells, for instance, secrete interferon, a chemical that rouses natural killer cells. ...
The Immune System
The Immune System

... between “self” molecules and “non-self” molecules. ...
To the Admissions Committee
To the Admissions Committee

... (V region) that was generated by V(D)J rearrangement (see Figure 1). By definition a cell expressing IgM on its surface (sIgM+) is a B lymphocyte. After stimulation by antigen in secondary lymphoid organs, B cells develop into antibody-secreting cells. T cells express only T cell receptor (TCR). Onl ...
The Body`s Lines of Defense
The Body`s Lines of Defense

...  A second line / third line of defence acts if the invader enters the body.  Leukocytes are white blood cells that may engulf invading microbes or produce antibodies.  Leukocytes that take part in phagocytosis are part of the bodies second line of defense and are non-specific.  Leukocytes that p ...
Methodic_students_3
Methodic_students_3

1. dia
1. dia

10 autoimmun
10 autoimmun

... Activation of APCs, which overcomes regulatory mechanisms and results in excessive T cell activation ...
IMMUNOTHERAPY
IMMUNOTHERAPY

Adaptive immunity
Adaptive immunity

... of all lymphocytes in the circulation. B. Monocytic lineage cells Mononuclear cells that differentiate from myeloid precursors are known as monocytes in the circulation or macrophages once they leave the circulation and enter the tissues. Monocytes are large mononuclear cells and account for approxi ...
Nociceptin mediated microvascular inflammation during sepsis
Nociceptin mediated microvascular inflammation during sepsis

Immune System:
Immune System:

... tears, saliva, nasal secretions and sweat that lyses cells. c. histamine prostaglandins, complements and leukotriens that promote inflammation by attracting leukocytes and stimulating phagocytes. d. the other chemical mediator is pyrogens released by neurophils and monocytes that stimulate fever pro ...
RFC_CP_Decouverte_immunologie_CIML
RFC_CP_Decouverte_immunologie_CIML

Immune Deficiency
Immune Deficiency

PowerPoint
PowerPoint

... Leukocidins Lyse phagocytes: Membrane attack complex ...
Immune System
Immune System

... Mucous membranes Secretions ...
IMMUNOLOGY The course includes laboratory exercises focused
IMMUNOLOGY The course includes laboratory exercises focused

Chimeric Immune System
Chimeric Immune System

...  T cells and B cells: white blood cells, more specific forms of protection ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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