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Non specific response to disease - Science Website
Non specific response to disease - Science Website

... Step 1 - When the pathogen enters, our body realises it is foreign because it has markers on its outer membrane. These markers are Antigens. (Our own cells have these but our body recognises that they are our own and not a threat) Step 2 - Antibodies in our blood attach to the foreign antigens and t ...
viruses - Alergia e Imunopatologia
viruses - Alergia e Imunopatologia

... Search for dsRNA/DNA activated proteins ...
Vaccinations teacher answer sheet 2 - e-Bug
Vaccinations teacher answer sheet 2 - e-Bug

... 8. Explain why vaccines are preventative in protecting against infection. Vaccines show the antigen for a particular infection to the immune system so that specific antibodies can be produced without the disease developing in the individual. If an individual contacts the disease naturally a vaccine ...
4 4 2nd line of defense and specific defenses
4 4 2nd line of defense and specific defenses

Ch6-Immune Desease
Ch6-Immune Desease

... • CYTOKINES are PROTEINS produced by MANY cells, but usually LYMPHOCYTES and MACROPHAGES, numerous roles in acute and chronic inflammation, AND immunity ...
Non-specific defense mechanisms
Non-specific defense mechanisms

... – used to attack bigger invaders “worms” ...
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Altered Immune Responses - rivier.instructure.com.
Altered Immune Responses - rivier.instructure.com.

... Cell- mediated Immunity • Cytokines – Immune response involves complex interactions of T-cells, B-cells, monocytes, and neutrophils - depends on Cytokines – Acts as messenger between the cell types – Instruct cells to alter their proliferation, differentiation, secretion, or activity – 60 different ...
An insatiable curiosity, combined with meticulous
An insatiable curiosity, combined with meticulous

... Mercedes Rincon, Ph.D., so good at what she does. Her laboratory investigations pinpoint the cellular activity that plays a role in immune system response, and have led to the identification of potential therapy targets for such diseases as flu infection, asthma, rheumatoid arthritis and breast canc ...
Nrsg 407 Disorders of the Immune System
Nrsg 407 Disorders of the Immune System

... • Allergy: exaggerated but otherwise normal immune response to foreign antigen regardless of the type of hypersensitivity reaction • Allergen: any substance (antigen) causing an allergic reaction • Atopy: allergy due to Type I • Most allergies are atopic ...
PRESS RELEASE 2011-10-03 The 2011 Nobel Prize in Physiology or Medicine
PRESS RELEASE 2011-10-03 The 2011 Nobel Prize in Physiology or Medicine

Exam #4
Exam #4

... Where do B cells come from? What is the role of B cells in humoral immunity (memory and plasma); what activates the process? Understand the difference between T-dependent and T-independent antigens, and how the former represents organization between cellular-mediated and humoral immunity. Explain wh ...
Immune system
Immune system

The Guardian at the Gate - Quintessential Health Care
The Guardian at the Gate - Quintessential Health Care

... • The lymph flows from the interstitial fluid through lymphatic vessels up to either the thoracic duct or right lymph duct, which terminate in the subclavian veins, where lymph is mixed into the blood. (The right lymph duct drains the right sides of the thorax, neck, and head, whereas the thoracic d ...
Lymphatic System Guided Notes
Lymphatic System Guided Notes

... Which cell has a similar function to NK cells? How are these two cells different? ...
Adaptive immunity Adaptive Immunity
Adaptive immunity Adaptive Immunity

... Clark & Cupper, JID 2005: „Immature dendritic cells are polarized by the binding of type 1, type 2, or regulatory PAMP and differentiate into mature dendritic that induce the formation of Th1, Th2, or T regulatory T cells, DCs decide on typecells of immune response respectively. In general, viral-as ...
Immunology --- prevention and treatment of infectious diseases
Immunology --- prevention and treatment of infectious diseases

... Human gut microbiota • The human body carries 100 trillion (1014) microorganisms in its intestines, 10 times more than the total number of human cells. • Beneficial roles of gut microbiota include: digestion, provide essential nutrients such as vitamin B and K, metabolize bile acids and xenobiotics ...
Clues
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... 1. The ___ pulp of the spleen is composed of nodules which contain large numbers of lymphocytes. 2. Endocytosis and destruction of particles by macrophages, etc. 3. Chemical released by antigen presenting cells or helper-T cells that activate and stimulate cell division & growth in B-cells & other T ...
Disease Unit Review
Disease Unit Review

4_28_15-PBS-Day 8 - Kenwood Academy High School
4_28_15-PBS-Day 8 - Kenwood Academy High School

Case 2: Necrotizing Fasciitis
Case 2: Necrotizing Fasciitis

... Necrotizing fasciitis (NF) is a severe soft tissue infection that can be caused by several bacteria, the best known being "flesh eating" Streptococcus pyogenes. Several other bacteria cause NF, including Gram positive Staphylococcus aureus and other Streptococcus spp. and Gram negative Klebsiella pn ...
Immune System Review
Immune System Review

... 1. the innate cellular and chemical defenses provide the body’s second line of defense 2. Phagocytes a. Phagocytes (macrophages, neutrophils, etc) engulf and destroy pathogens that breach epithelial barriers. This process is facilitated when opsonins (antibodies or complement to which the phagocyte’ ...
Leaky gut, leaky brain: the role of zonulin
Leaky gut, leaky brain: the role of zonulin

... • The BBB includes endothelial cells and TJs. • Astrocytes located beneath endothelial cells prevent entry of unwanted molecules across the ...
Benlysta(belimumab)
Benlysta(belimumab)

... • is a systemic autoimmune disease (or autoimmune connective tissue disease) that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage. It is a Type III hypersensitivity reaction ca ...
skin and immune system
skin and immune system

... by marking them for destruction and elimination •Functions by being able to recognize proteins on the surface of cells ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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