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幻灯片 1
幻灯片 1

... autoimmune hemolytic anemia ...
Congratulations / Félicitations - Canadian Society for Immunology
Congratulations / Félicitations - Canadian Society for Immunology

... conclusively that thymocyte selection is based on an affinity/avidity model. Dr. Ohashi has extended her work on T cell tolerance to evaluate tumor immunity where she has demonstrated that ignorant T cells could be activated against tumors. More recently, she has shown that altering the molecular pr ...
Type III Hypersensitivity
Type III Hypersensitivity

... • Degraded DNA or RNA stimulate B cell to produce antibody ( anti-nuclear Ab ) • Formation and deposition of Ag-Ab complex ...
Activated B Cell
Activated B Cell

... dominant autoimmune response is the production of an array of autoantibodies to self antigens including nuclear components (DNA, RNA, histones) as well as autoantibodies to cell membrane determinants on hematopoietic cells including (RBC, platelets and leukocytes). • The autoantibodies induce injury ...
The immune system  Dr. Ali Ebneshahidi © 2016 Ebneshahidi
The immune system Dr. Ali Ebneshahidi © 2016 Ebneshahidi



... inhibitors and the rising interest in bispecific targeting constructs, specific activation of iNKT and Vγ9Vδ2-T cells has more potential than ever before. Multiple studies have shown immunological, biochemical and even clinical responses in patients treated with specific activating ligands, undersco ...
128. immune_team_
128. immune_team_

... • Is a deficiency of an enzyme which is responsible for prevention of ] C1 self-activation [ • because it’ll attack the body’s own cells, and cause inflammation usually in the ] uvula [ which leads to choking till death. • So these patients always have adrenaline in their pockets to prevent the swal ...
Classification
Classification

... elongation of cells & helps promote the growth of fruit…during fall auxin levels decrease causing ripened fruit to fall and plants will lose their leaves  Abscisic Acid – inhibits plant growth during times of stress such as cold temperature or drought  Gibberellins – growth hormones that cause pla ...
Lecture: T Cell Activation and Regulation
Lecture: T Cell Activation and Regulation

Chapter 19 Disorders Associated with the Immune System
Chapter 19 Disorders Associated with the Immune System

... Privileged tissue, such as pig heart valves, is not antigenic and does not stimulate an immune response. A development that promises to transform transplantation medicine is the use of stem cells. These are pluripotent—that is, they can generate cell types such as nerve, blood, or other cells. Stem ...
Chapter 5 Protein Function
Chapter 5 Protein Function

... directed at bacterial infection and extracellular virus in body fluid, also respond to the proteins produces in these organism. Cellular immune system destroys hosts infected by viruses, some parasites, and foreign tissues 與器官移植的排斥有關 ...
11.1 Defence against infectious disease – summary
11.1 Defence against infectious disease – summary

... natural immunity – immunity due to infection / acquisition from mother; artificial immunity – due to inoculation with vaccine / antibodies / vaccination; ...
chapter17
chapter17

Chronic Inflammation
Chronic Inflammation

General Pathology: Acute Inflammation
General Pathology: Acute Inflammation

... rapid destruction (within minutes to hours) of transplantion – Acute  failure of immunosuppression so that antibodies develop in the weeks or months following transplantation – Chronic  immunosuppression can not (yet) be perfect, small amounts of damage accumulate over years and eventually destroy ...
Avoiding Chronic Inflammation
Avoiding Chronic Inflammation

... As the Lactobacillae are non pathogenic it is likely that if they do have a function they will work agonistically to produce an immunosuppressive response but they could theoretically function as an antagonist of IL-10. It is very hard to predict possible functions, if any, based on a small amount o ...
Harnessing the immune system to combat cancer
Harnessing the immune system to combat cancer

ACUTE INFLAMMATORY RESPONSE – EXTRAVASATION AND
ACUTE INFLAMMATORY RESPONSE – EXTRAVASATION AND

lurie prize in biomedical sciences recipients
lurie prize in biomedical sciences recipients

... at Stanford University and a Howard Hughes Medical Institute Investigator. He pioneered the field of optogenetics, which has greatly expanded our understanding of normal behavior as well as of diseases like Parkinson’s, schizophrenia and depression by combining genetic manipulation and optics to act ...
Stem Cell Therapy Reverses Diabetes: Stem Cells
Stem Cell Therapy Reverses Diabetes: Stem Cells

... passes lymphocytes separated from a patient's blood over immobilized cord blood stem cells (CBSC) from healthy donors. After two to three hours in the device the re-educated lymphocytes are returned to the patient. The progress of the patients was checked at 4, 12, 24 and 40 weeks after therapy. ...
Rapid innate control of antigen abrogates adaptive immunity
Rapid innate control of antigen abrogates adaptive immunity

... infection with high viral load whereby a robust CD4+mediated T-cell response could induce widespread immunopathology (Fig. 1). Using lymphocytic choriomeningitis virus (LCMV) infection, Waggoner et al.9 demonstrated the effects of increasing the infecting dose of virus on interplay between NK cells ...
PPT 21
PPT 21

Psychoneuroimmunology
Psychoneuroimmunology

... Resistance: stress induced downregulation of GCR; cortisol cannot restrain pro-inflammatory cytokine production so cytokine production increases (animal/human ...
Dead cell-associated antigens
Dead cell-associated antigens

... Capture of lymph borne viruses and guide them to presentation and activation of B cell ...
The Hallmarks of Cancer - Roswell Park Cancer Institute
The Hallmarks of Cancer - Roswell Park Cancer Institute

... • Tumors disable parts of the immune system by secreting or recruiting cells that secrete immunosuppressive factors (ex. TGF B) ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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