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T cells T cells
T cells T cells

...  TH1 cells cooperate with macrophages and transform them in activated (NO production - destroy intracellular parasites)  Activated macrophages secrete some cytokines (IL-1, TNF, ...) that help to stimulate T cells and stimulate local inflammation, which helps suppress infection  Interaction betwe ...
Lymphatic System and Immunity
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svhs advanced biology - Sonoma Valley High School
svhs advanced biology - Sonoma Valley High School

... Lab Biology students regarding the immune system. Each group will prepare a 12 to 20 slide project regarding a segment of the immune system. All of the files will then be linked together as a single tutorial with all the topics. for use by Lab Biology students. ...
Διαφάνεια 1 - rheumatology.gr
Διαφάνεια 1 - rheumatology.gr

... The (+) charged pocket P4 of the epitope does not react with the (+) charged Arginine, but does with the neutral Citrulline Citrullination of HLA binding peptide 100-fold increase in peptide-MHC affinity CD4+T cell activation in HLA DRB1 ...
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General Pathology of Neoplasia - Wk 1-2

... agents are responsible for causing genetic damage that may lead to malignancy. These include: 1. Chemical compounds such as polycyclic hydrocarbons. 2. Radiation, both ultraviolet and ionising. 3. Oncogenic Viruses (HPV, EBV, HTLV-1, HBV, HCV). Incorporation of the viral genome can cause transcripti ...
Schedule for Lectures of the Summer School “Molecular Interactions
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Using nCounter® RNA:Protein Profiling Technology

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chapter 43 - Course Notes

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Immune Support - Huntington College of Health Sciences
Immune Support - Huntington College of Health Sciences

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Chapter 1 – Introduction to the Immune Response
Chapter 1 – Introduction to the Immune Response

... attacks, it furnishes common molecular structures on its own surface, or on the surface of cells it has infected, or as part of products it synthesizes. These structures are called pathogen-associated molecular patterns (PAMPs). Cell damage or death in the absence of a pathogen gives rise to DAMPs o ...
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... • Marginal zone B cells: reside in marginal zone of spleen where they can respond to particulate antigen in blood (bacteria, etc.); also dependent on BAFF for survival. Also dependent on Notch signaling • B1 B cells: prominent in peritoneal and pleural cavities, present in spleen, absent in lymph no ...
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... • Many Infectious agents and many diseases • Bacteria can Infect any part of the body • Cause disease due to – Growth of the microbe in a tissue – Produce Bacterial factors that are harmful to host – Elicite an inflammatory response that causes damage • but also leads to aquired immunity ...
svhs advanced biology - Sonoma Valley High School
svhs advanced biology - Sonoma Valley High School

... Explain how the circulatory system and its vessels differ from the lymphatic system and its vessels. Describe the role of lymph nodes found in various areas of the body. Explain what metastasis means and how it relates to the lymphatic system. Explain what the tonsils, spleen, thymus gland have in c ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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