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The Human Immune System
The Human Immune System

... displays the antigen for a T-cell T-cell learns pathogen and hunts out infected cells Once found, T-cells destroy infected cells (thru a process known as apoptosis) ...
Yukon Immunization Manual: Section 14
Yukon Immunization Manual: Section 14

...  Phagocytosis  Molecular Response  Inflammatory Response ...
Immunomodulation and Cancer
Immunomodulation and Cancer

... 3. Lymphomagenesis model • B cell lymphomas occur at different steps of B-cell development and represent their malignant counterpart • Lymphomas arise from errors occurring at hyper-mutable stages of B cell development – Genetic hallmark is chromosomal translocations resulting from aberrant rearran ...
Poliomyelitis
Poliomyelitis

... Dual Tropism Thought to be the Cause of Poliomyelitis from Poliovirus • Reflects the distribution of the poliovirus receptor CD155 on cells lymphoid cells as well as the epithelial cells in the gut and on neurons in the ...
12 Chapter 38 Rodent - University of Northern Colorado
12 Chapter 38 Rodent - University of Northern Colorado

... Blood (acute) ...
Sepsis-induced Innate and Adaptive Immune
Sepsis-induced Innate and Adaptive Immune

... are the first cellular responders to invading organisms and are therefore vital to host defense. Cell types including monocytes (and their mature form, tissue macrophages), dendritic cells, and neutrophils recognize pathogens through constitutively expressed receptors including toll-like receptors ( ...
ppt - med.muni
ppt - med.muni

... Damage by complement and proinflammatory mediators ...
The Adaptive Immune Response: T lymphocytes
The Adaptive Immune Response: T lymphocytes

... Many cell types express class I molecules for the presentation of intracellular antigens. These MHC molecules may then stimulate a cytotoxic T cell immune response, eventually destroying the cell and the pathogen within. This is especially important when it comes to the most common class of intracel ...
24. The Body`s Defenses
24. The Body`s Defenses

... • Activated helper T cells promote the immune response, particularly secretion of stimulatory proteins – Make helper T cells grow and divide, producing memory cells and additional helper T cells – Help activate B cells, stimulating humoral ...
Autoimmunity - Egyptian Society of Pediatric Allergy and Immunology
Autoimmunity - Egyptian Society of Pediatric Allergy and Immunology

... family bind to ligand-specific (high affinity) Trk receptors. In addition, all neurotrophins bind to the common pan-neurotrophin (low affinity) receptor p75NTR. The high affinity receptors mediate trophic effects, whereas the low affinity receptor may be involved in induction of apoptosis. 2-Neurotr ...
CARBOHYDRATES
CARBOHYDRATES

... Functions: Build cell membranes, form our chromosomes, act as enzymes which cause chemical reactions to occur in cells Composed of the following elements: C, H, O, ...
Cytokines and Chemokines
Cytokines and Chemokines

... a diverse group of soluble proteins and peptides which act as humoral regulators at nano- to- picomolar concentrations • Cytokines modulate the functional activities of individual cells and tissues both under normal and pathologic conditions • Interleukins - produced exclusively by leukocytes • Lymp ...
SKIN BIOLOGY - Ministry of Public Health
SKIN BIOLOGY - Ministry of Public Health

... • The sentitizing substance (hapten), combines with a protein in the skin to form the allergen • The Langerhans cells in the stratum germinativum interacts with the allergen and migrates to the lymphoid gland • It then “teaches” the T cells about the ...
LECTURE 1 INTRODUCTION TO IMMUNOLOGY I Definition of
LECTURE 1 INTRODUCTION TO IMMUNOLOGY I Definition of

... Endothelial cells forming the sinusoids ...
Phagocytic Cells - Cathedral High School
Phagocytic Cells - Cathedral High School

... – Give the skin a pH between 3 and 5, which is acidic enough to prevent colonization of many microbes – Also include proteins such as lysozyme, an enzyme that digests the cell walls of many bacteria Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings ...
1b) ch 2 Aging Theories - Cal State LA
1b) ch 2 Aging Theories - Cal State LA

... To selectively destroy foreign proteins, the immune system must recognize the structures of all of the many proteins present in the body and suppress its tendency to form Abs against these body proteins ...
Ch. 39 Plant Responses to Internal and External Signals notes
Ch. 39 Plant Responses to Internal and External Signals notes

...  Distasteful or toxic compounds  Canavanine (replaces arginine when ingested)  Attraction of parasitoid wasps 4 Recruitment of parasitoid wasps that lay their eggs within caterpillars ...
Blood and the circulatory system
Blood and the circulatory system

... Function #3- Facilitating immune responses by recognizing microbes or abnormal cells and killing them directly or by antibodies. ...
Chapter 43 - FacStaff Home Page for CBU
Chapter 43 - FacStaff Home Page for CBU

... Insects defend themselves by mechanisms similar to those of vertebrates. Hemocytes of insects ingest bacteria and damaged cells. Invertebrates have a simple defense system. Their system is nonspecific. Invertebrates in general do not have immunological memory. Earthworms have immunological memory. E ...
Draft FACT Immune Effector Cell Interim Standards 1 FACT IMMUNE
Draft FACT Immune Effector Cell Interim Standards 1 FACT IMMUNE

... Cellular therapy product: Somatic cell-based product (e.g., mobilized HPC, mononuclear cells, cord blood cells, mesenchymal stromal cells, T cells) that is procured from a donor and intended for processing and administration. Cytokine release syndrome: A reaction from the release of cytokines from c ...
NOTE: The provided figures may be useful and beneficial
NOTE: The provided figures may be useful and beneficial

... a. A receptor binding to a ligand b. An enzyme binding to a substrate c. An antibody/T-cell receptor binding to an antigen. 5. Use Figure 43.9 to describe the function of MHC molecules on both types of T cells. 6. Use Figure 43.11 to compare & contrast alternative mRNA splicing and immune cell recep ...
No Slide Title
No Slide Title

... PRESENTING CELL BY ENDOCYTOSIS • DIGEST IN PHAGOLYSOSOME • FRAGMENTS COMBINE WITH PREFORMED MHC CLASS II • DISPLAYED ON PLASMA MEMBRANE • RECOGNIZED BY CD4 + CELLS ...
tolerance
tolerance

... An interaction of these B cells with Fasligand-bearing cells results in their death via apoptosis. ...
FREE Sample Here
FREE Sample Here

... follicles of secondary lymphoid tissues? (Select all that apply.) a. They are bone marrow derived hematopoietic cells. b. They provide a stable depository of intact antigens able to bind to B-cell receptors. c. They have a large surface area as a result of forming dendrites. d. They internalize immu ...
Group A
Group A

... and viruses • There are two types of lymphocytes: T cells and B cells – T cells - attack foreign cells directly – B cells give rise to plasma cells, which produce antibodies ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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