Gene Section EIF3C (eukaryotic translation initiation factor 3, subunit C)
... and was overexpressed in meningiomas that had lost merlin expression. EIF3c overexpression can also transform NIH/3T3 fibroblasts, indicated by decreased doubling times, increased clonogenicity, increased viability, facilitated S-phase entry, attenuated apoptosis, formation of transformed foci, and ...
... and was overexpressed in meningiomas that had lost merlin expression. EIF3c overexpression can also transform NIH/3T3 fibroblasts, indicated by decreased doubling times, increased clonogenicity, increased viability, facilitated S-phase entry, attenuated apoptosis, formation of transformed foci, and ...
Introduction: plant cell wall proteins
... the plasma membrane and then processed for release to the cell wall and/or as extracellular secretions. The expression of AGP genes is then considered along with the localization patterns of various AGPs; these data highlight the involvement of AGPs in plant development. Whereas AGPs are likely to h ...
... the plasma membrane and then processed for release to the cell wall and/or as extracellular secretions. The expression of AGP genes is then considered along with the localization patterns of various AGPs; these data highlight the involvement of AGPs in plant development. Whereas AGPs are likely to h ...
Answers to End-of-Chapter Questions – Brooker et al ARIS site
... c. organize the inner nuclear membrane. d. all of the above. e. a and c only. Answer: e. The proteins in the nucleus provide two important organizational functions: organization of the inner nuclear membrane and organization of the chromosomes in their chromosomal territory. 6. The cytoskeleton is ...
... c. organize the inner nuclear membrane. d. all of the above. e. a and c only. Answer: e. The proteins in the nucleus provide two important organizational functions: organization of the inner nuclear membrane and organization of the chromosomes in their chromosomal territory. 6. The cytoskeleton is ...
Organic chemistry
... • Provide long term energy to an organism • Provides structure of cell membranes (phospholipids) • Insulation • Saturated vs. Unsaturated ...
... • Provide long term energy to an organism • Provides structure of cell membranes (phospholipids) • Insulation • Saturated vs. Unsaturated ...
Gene Section YPEL3 (yippee-like 3 (Drosophila)) Atlas of Genetics and Cytogenetics
... detected in 9 commercial and 30 patient ovarian tumors. In Cp70 ovarian cells, hypermethylation of a CpG island immediately upstream of the YPEL3 promoter is suggested to be the basis for the observed down-regulation (Kelley et al., 2010). ...
... detected in 9 commercial and 30 patient ovarian tumors. In Cp70 ovarian cells, hypermethylation of a CpG island immediately upstream of the YPEL3 promoter is suggested to be the basis for the observed down-regulation (Kelley et al., 2010). ...
Cell Structure and Function
... phosphorylation of a protein that triggers the cell’s response • Protein phosphatases (PP) remove the phosphate from the kinases and the final protein so they can all be reused ...
... phosphorylation of a protein that triggers the cell’s response • Protein phosphatases (PP) remove the phosphate from the kinases and the final protein so they can all be reused ...
Info-PubMed
... An InteractionBox is indicated in the leftmost position in the box as Interaction. In an InteractionBox, two figures are followed by the names of the two gene/protein which co-occur in the same sentences. The first figure is the number of sentences in Medline which are judged to express direct inter ...
... An InteractionBox is indicated in the leftmost position in the box as Interaction. In an InteractionBox, two figures are followed by the names of the two gene/protein which co-occur in the same sentences. The first figure is the number of sentences in Medline which are judged to express direct inter ...
Biology 102 Lecture 12: From DNA to Proteins
... Introns must be removed and exons joined together Called RNA splicing ...
... Introns must be removed and exons joined together Called RNA splicing ...
Methods for Control of Microbial Growth
... Heat-Based Microbial Control Processes • Incineration/ baking achieve sterility • Autoclaving: sterilization with live steam and pressure, very widely used • Pasteurization: flash heat treatment (63°C - 66°C for 30 minutes) that reduces the bio-burden of food materials (kills Salmonella and Listeri ...
... Heat-Based Microbial Control Processes • Incineration/ baking achieve sterility • Autoclaving: sterilization with live steam and pressure, very widely used • Pasteurization: flash heat treatment (63°C - 66°C for 30 minutes) that reduces the bio-burden of food materials (kills Salmonella and Listeri ...
AP Protein Synthesis Quiz
... of more than one polypeptide chain. c. many genes code for RNA molecules that have no enzymatic activity. d. A and B only e. A, B, and C 2. Which of the following represents a similarity between RNA and DNA? a. Both are double-stranded. b. the presence of uracil c. the presence of an OH group on the ...
... of more than one polypeptide chain. c. many genes code for RNA molecules that have no enzymatic activity. d. A and B only e. A, B, and C 2. Which of the following represents a similarity between RNA and DNA? a. Both are double-stranded. b. the presence of uracil c. the presence of an OH group on the ...
Introduction to biological databases
... 3D structure prediction Structure still available for a limited number of proteins Effort to predict protein structures based on sequences similarities Still not very accurate! ...
... 3D structure prediction Structure still available for a limited number of proteins Effort to predict protein structures based on sequences similarities Still not very accurate! ...
survey of biochemistry - School of Chemistry and Biochemistry
... Suppose you have a protein mixture and you need to determine the protein concentration. You cannot use Beer’s Law. Because you would not know the extinction coefficient for the protein mixture at 280 nm ...
... Suppose you have a protein mixture and you need to determine the protein concentration. You cannot use Beer’s Law. Because you would not know the extinction coefficient for the protein mixture at 280 nm ...
The Disease(text in English)
... The cause In general, mutations in CDKL5 are considered the cause of the disease if the are present in the child but not in the healthy parents. Therefore, these mutations arise “de novo” at the moment of the conception. The diagnosis The initial diagnosis is a clinical one or, with other words, bas ...
... The cause In general, mutations in CDKL5 are considered the cause of the disease if the are present in the child but not in the healthy parents. Therefore, these mutations arise “de novo” at the moment of the conception. The diagnosis The initial diagnosis is a clinical one or, with other words, bas ...
Protein Interactions in an Organism Compose the Interactome
... Relationship between Genotype and Phenotype ...
... Relationship between Genotype and Phenotype ...
Proteins
... THREE fatty acids. (Fig 5-10 pg 65). When created, it is called triacylglycerol, or triglyceride. Phospholipids are formed from TWO fatty acids and a glycerol. They are usually the skeleton of a cell membrane ...
... THREE fatty acids. (Fig 5-10 pg 65). When created, it is called triacylglycerol, or triglyceride. Phospholipids are formed from TWO fatty acids and a glycerol. They are usually the skeleton of a cell membrane ...
Translation
... •The control in the DNA transcription process is very tight. •Cells are able to "turn on" or "turn off" genes when their products are not required in cell metabolism or control. • Regulation of gene expression is now only being to be fully understood and is a major area of research today. ...
... •The control in the DNA transcription process is very tight. •Cells are able to "turn on" or "turn off" genes when their products are not required in cell metabolism or control. • Regulation of gene expression is now only being to be fully understood and is a major area of research today. ...
MS Word file
... Transfer-messenger RNA binds to A site of ribosome and acts as template. Alanine is initially added, then 10 amino acids encoded by tmRNA These serve as tag for rapid degradation of protein Termination codon is contained on tmRNA and termination ...
... Transfer-messenger RNA binds to A site of ribosome and acts as template. Alanine is initially added, then 10 amino acids encoded by tmRNA These serve as tag for rapid degradation of protein Termination codon is contained on tmRNA and termination ...
a version - SEA
... patch tests were suggestive of Taptic lysogens; however, stable lysogens were not formed as host cells were consistently lysed over time. The role of gp38 in the Taptic life cycle remains to be explored. In other experiments, the computational prediction that Butters gp31 is a transmembrane protein ...
... patch tests were suggestive of Taptic lysogens; however, stable lysogens were not formed as host cells were consistently lysed over time. The role of gp38 in the Taptic life cycle remains to be explored. In other experiments, the computational prediction that Butters gp31 is a transmembrane protein ...
Proteins – where do they come from?
... • The mRNA is either read by another ribosome or it is recycled so its nucleotides can be used again. • The ribosome large and small subunit falls apart from each other ...
... • The mRNA is either read by another ribosome or it is recycled so its nucleotides can be used again. • The ribosome large and small subunit falls apart from each other ...
書面報告
... Bioinformatics played a decisive role in the most prominent scientific achievements during recent years, the sequencing of the human genome. ...
... Bioinformatics played a decisive role in the most prominent scientific achievements during recent years, the sequencing of the human genome. ...
osmolarity regulates gene expression in intervertebral disc cells
... within the top 2% of highest average intensity values (n=174), a significant number related to extracellular matrix (21, 28%) and cytoskeleton proteins (12, 16%). Many of these proteins were recognized as important products of fibrochondrocyte biosynthesis, including types I, III and VI collagen, de ...
... within the top 2% of highest average intensity values (n=174), a significant number related to extracellular matrix (21, 28%) and cytoskeleton proteins (12, 16%). Many of these proteins were recognized as important products of fibrochondrocyte biosynthesis, including types I, III and VI collagen, de ...
Disentangling factors of gene expression regulation in human
... Additionally, in higher eukaryotes the same gene can potentially lead to a number of different transcripts through alternative splicing. We have recently demonstrated that in human tissues most genes express only one transcript to significantly higher levels than ...
... Additionally, in higher eukaryotes the same gene can potentially lead to a number of different transcripts through alternative splicing. We have recently demonstrated that in human tissues most genes express only one transcript to significantly higher levels than ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.