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Animal Nutrition and Feeds
Animal Nutrition and Feeds

... body processes which transforms food into body tissues and energy. ...
University of Birmingham Armadillo
University of Birmingham Armadillo

... about how a subset of these proteins function. The structure of ARM-repeats allows proteins containing them to be functionally very versatile. Are the ARMrepeat proteins in ‘little creatures’ as multifunctional as their better-studied relatives? The time is now right to start analysing ARM-repeat pr ...
ORGANIC ACID DISORDERS This disorder is caused by a
ORGANIC ACID DISORDERS This disorder is caused by a

... measured by Tandem Mass Spectrometry method. Treatment: Aggressively treat acute acidosis. Avoid fasting, eat frequently and restrict protein intake. Intravenous glucose can be used when child is vomiting or has a fever. Monitor urinary ketones for metabolic crisis. Incidence: Very rare- < 50 cases ...
Identifying proteins required for chromatin organization using a GFP
Identifying proteins required for chromatin organization using a GFP

... to inappropriate progression through the cell cycle. Such progression can cause prolific cell division allowing cells to bypass cellular checkpoints and divide uncontrollably. Gene expression can be affected by a number of factors such as chromatin organization. When the chromatin organization is di ...
Bioinformatics Resources and Tools on the Web: A Primer
Bioinformatics Resources and Tools on the Web: A Primer

... • Similarity: The gene looks like a specific known gene – Procrustes,… ...
enzymes
enzymes

... • Natural organic catalysts made of protein that lower the activation energy so a reaction can occur fast enough for cell to survive ...
Protein kinases
Protein kinases

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F1000 - CBGP
F1000 - CBGP

... M. oryzae is a very important plant pathogen and is responsible for large amounts of rice and wheat culture destruction every year that is associated with major economical losses. Although a large number of factors have been previously shown to be implicated in this filamentous fungal virulence, thi ...
Teaching old NCATs new tricks: using non
Teaching old NCATs new tricks: using non

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OrthologAnalysis
OrthologAnalysis

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Proteins and Enzymes
Proteins and Enzymes

... http://www.elmhurst.edu/~chm/vchembook/584proteinsyn.html ...
Secretion of Beta-Lactamase Requires the Carboxyl End of the Protein.
Secretion of Beta-Lactamase Requires the Carboxyl End of the Protein.

... the transport of these proteins into or across membranes (Milstein et al., 1972; Blobel and Dobberstein, ...
Polar location and functional domains of the Agrobacterium
Polar location and functional domains of the Agrobacterium

... VirD4 was not dependent on T-DNA processing, the formation of the transport apparatus and the presence of other Vir proteins. VirD4 is an integral membrane protein with one periplasmic domain. The large cytoplasmic region contains a nucleotide-binding domain. To investigate the role of these domains ...
A REVIEW OF MICROBIAL PROTEIN PRODUCTION: PROSPECTS
A REVIEW OF MICROBIAL PROTEIN PRODUCTION: PROSPECTS

... source of protein for human food as it gives promising fate as an alternative source of protein. The use of microorganisms in the cultivation of this protein have many advantages over the conventional protein including, their short doubling time, easy cultivation, utilization of many cheap/widely av ...
De novo assembled expressed gene catalog of a
De novo assembled expressed gene catalog of a

... Supplemental Table S4. List of 43 transcript-derived contigs homologous to 33 of the 52 “Core xylem genes” identified by Ko et al.[1] in Arabidopsis and their relative xylem to leaf FPKM ratio. In most cases, the expression profiles of these genes were highly positively correlated with that of EgCes ...
Globin Gene Exercise
Globin Gene Exercise

... two introns are removed, the three exons join into one continuous coding sequence, in one reading frame. (The reading frame appears to have switched when looking at the Map of β-Globin Gene©, but simply because the number of nucleotides in each of the two introns is not a multiple of three.) Can int ...
Mapping functional regions of the segment
Mapping functional regions of the segment

... subfamily of proteins that have very similar zinc fingers and which recognize identical or very closely related GC-rich sequences. So far, three other members have been identified: Krox-24 (also known as Egr-1, Zif268, NGFI-A and TIS8 (8-12)), EGR-3 (13) and NGFI-C (14). Although these proteins are ...
Proportion of animal protein Consumption
Proportion of animal protein Consumption

... Some of the animal-derived dietary proteins are much more positive in their δ13C values than those from plant sources. ...
Proteinstruktur und
Proteinstruktur und

... phosphoethanolamine bridge with Man (this occurs only on membrane associated proteins) • The two most common forms are O- and N- linked ...
Lookup a Gene of Interest: PROTEOME
Lookup a Gene of Interest: PROTEOME

... Note: You may optionally save your results as a list, export them in tabdelimited format, load them in the Pathfinder visualization tool, or load them in the Ontology Search tool by clicking the desired link. You may also use the search within results pull-down menu to identify detailed information ...
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specs

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Test for protein expression on IPTG induction
Test for protein expression on IPTG induction

... a future data) to see if a new protein of the predicted size is produced on IPTG induction. At least one group should also repeat this experiment with the parent BL21(DE3) E. coli strain as a control. The starting point to test for IPTG induction should be a well-oxygenated fairly fresh culture. The ...
Lecture 5
Lecture 5

... 5) Ribosome binding occur in Shine-Delgarno-like sequence motif in the 5’-UT of mRNA. 6) Not coupled to transcription and trnaslational units can occur as stable ribonucleoprotein complexes. ...
New high-throughput NMR
New high-throughput NMR

... three of them [1,2].‘If we get the same phenotype with all three methods, we can be sure it is not an artefact,’ explains Atugen’s CSO Klaus Giese.And in more recent months,Atugen have also employed those three knockdown tools to discover novel targets, namely in the PI3 kinase pathway. ...
Document
Document

... involved into formation of the whole organism body. •Motor proteins. These proteins can convert chemical energy into mechanical energy. actin and myosin are responsible for muscular motion. •Receptors These proteins are responsible for signal detection and translation into other type of signal. •Sig ...
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Protein moonlighting



Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.
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