Releasable conjugation of polymers to proteins
... permit the selective modification of all solvent exposed amino acid residues of a given sort. There currently exist residue-specific reactions for permanently coupling polymers to at least 10 out of the 20 canonical amino acids found in proteins.7-10 However, in many cases, polymer-modification can ...
... permit the selective modification of all solvent exposed amino acid residues of a given sort. There currently exist residue-specific reactions for permanently coupling polymers to at least 10 out of the 20 canonical amino acids found in proteins.7-10 However, in many cases, polymer-modification can ...
De Robertis 1.pm
... CR domains of the type present in Chordin are found in many other extracellular space proteins. These include the fibrillar procollagens (type I, III and V), amnionless, neuralin-1 and 2, CRIM-1, crossveinless-2 and CTGF. Neuralins contain three cysteine-rich domains and can bind Tsg, which promotes ...
... CR domains of the type present in Chordin are found in many other extracellular space proteins. These include the fibrillar procollagens (type I, III and V), amnionless, neuralin-1 and 2, CRIM-1, crossveinless-2 and CTGF. Neuralins contain three cysteine-rich domains and can bind Tsg, which promotes ...
Literature retrieval
... was greater than 1%, then it was considered common. We chose this somewhat high cutoff percentage because some of the most investigated genes (p53 for example) have a baseline occurrence of 1%. (vi) Common phrase gene names (i.e., those for which each term in the name is a common word, such as ‘nove ...
... was greater than 1%, then it was considered common. We chose this somewhat high cutoff percentage because some of the most investigated genes (p53 for example) have a baseline occurrence of 1%. (vi) Common phrase gene names (i.e., those for which each term in the name is a common word, such as ‘nove ...
Name The Lac Operon Go to the following bozemanscience website
... 6. What happens when lactose is NOT present? What occurs within the operon region as a result? 7. What is the function of the trp Operon? 8. What occurs within the operon when tryptophan is present? 9. What happens when tryptophan is not present? 10. How do the two types of operons exhibit a feedbac ...
... 6. What happens when lactose is NOT present? What occurs within the operon region as a result? 7. What is the function of the trp Operon? 8. What occurs within the operon when tryptophan is present? 9. What happens when tryptophan is not present? 10. How do the two types of operons exhibit a feedbac ...
Mutation - SD43 Teacher Sites
... Harmful mutations, known as negative mutations, can cause a species to become extinct. Most often, however, errors in the base sequence of DNA appear to have no effect on the organism. These types of mutations are called neutral mutations. Positive mutation Millions of people worldwide are infected ...
... Harmful mutations, known as negative mutations, can cause a species to become extinct. Most often, however, errors in the base sequence of DNA appear to have no effect on the organism. These types of mutations are called neutral mutations. Positive mutation Millions of people worldwide are infected ...
Global absolute quantification reveals tight regulation of protein
... ing studies have revealed cellular heterogeneity and stochastic gene expression at the single-cell level, which are overseen in analyses on cell populations. Such single cell variations can be caused by differences in cell-cycle phase, developmental stage, local signaling concentrations, transcripti ...
... ing studies have revealed cellular heterogeneity and stochastic gene expression at the single-cell level, which are overseen in analyses on cell populations. Such single cell variations can be caused by differences in cell-cycle phase, developmental stage, local signaling concentrations, transcripti ...
1754-6834-4-30-S5
... theoretical absorption coefficient calculated from the primary sequence. ClCBH2b was purified using the same chromatography steps as TeCBH1-TrCBM-C, DEAE anion exchange followed by phenyl HIC. In this purification, ClCBH2b is found in the flow through of the DEAE step and is eluted from the phenyl H ...
... theoretical absorption coefficient calculated from the primary sequence. ClCBH2b was purified using the same chromatography steps as TeCBH1-TrCBM-C, DEAE anion exchange followed by phenyl HIC. In this purification, ClCBH2b is found in the flow through of the DEAE step and is eluted from the phenyl H ...
Structures Macromolecular - CNB
... and on the virus-cell interplay at distinct stages, including entry, replication, assembly and maturation. These groups work with various approaches, with special emphasis on X-ray crystallography, advanced electron and X-ray microscopy, and tomography. Cell organelles such as the centrosome, centro ...
... and on the virus-cell interplay at distinct stages, including entry, replication, assembly and maturation. These groups work with various approaches, with special emphasis on X-ray crystallography, advanced electron and X-ray microscopy, and tomography. Cell organelles such as the centrosome, centro ...
Claudins, dietary milk proteins, and intestinal barrier regulation
... of molecules between cells.1 Tight junctions are composed of membrane-spanning proteins, whose components traverse the paracellular space, and scaffolding proteins, which link membrane proteins directly to the actin cytoskeletal network. As shown in Figure 1,2 membrane-spanning proteins, including cl ...
... of molecules between cells.1 Tight junctions are composed of membrane-spanning proteins, whose components traverse the paracellular space, and scaffolding proteins, which link membrane proteins directly to the actin cytoskeletal network. As shown in Figure 1,2 membrane-spanning proteins, including cl ...
Ivy Mead 24 February 2011 Bioinformatics Lab report 3 The analysis
... The analysis for Telomerase Reverse Transcriptase (TERT) has been done at the protein level because the evaluation can provide a more clear distinction between those kind of sequences. Because transcriptase is such an important protein for maintaining DNA quality, it is less likely to change in monu ...
... The analysis for Telomerase Reverse Transcriptase (TERT) has been done at the protein level because the evaluation can provide a more clear distinction between those kind of sequences. Because transcriptase is such an important protein for maintaining DNA quality, it is less likely to change in monu ...
Blast intro slides ppt
... that affects humans – If yeast contain a protein that is related (homologous) to the protein involved in cystic fibrosis – Then yeast can be used as a model organism to study this disease • Study of the protein in yeast will tell us about the function of the protein in humans David Form - August 15, ...
... that affects humans – If yeast contain a protein that is related (homologous) to the protein involved in cystic fibrosis – Then yeast can be used as a model organism to study this disease • Study of the protein in yeast will tell us about the function of the protein in humans David Form - August 15, ...
BLAST intro slides ppt
... that affects humans – If yeast contain a protein that is related (homologous) to the protein involved in cystic fibrosis – Then yeast can be used as a model organism to study this disease • Study of the protein in yeast will tell us about the function of the protein in humans David Form - July 2014 ...
... that affects humans – If yeast contain a protein that is related (homologous) to the protein involved in cystic fibrosis – Then yeast can be used as a model organism to study this disease • Study of the protein in yeast will tell us about the function of the protein in humans David Form - July 2014 ...
Lecture 6
... DNA/RNA Electrophoresis Double stranded DNA or RNA are molecules that repel themselves. They will all form rod-like structures. So now we can separate our nucleic acids on the basis of size. We can visualize with a fluorescent dye (usually ethidium bromide) and compare to a standard to get a relati ...
... DNA/RNA Electrophoresis Double stranded DNA or RNA are molecules that repel themselves. They will all form rod-like structures. So now we can separate our nucleic acids on the basis of size. We can visualize with a fluorescent dye (usually ethidium bromide) and compare to a standard to get a relati ...
Ancient Ciphers: Minireview Translation in
... repeats surrounding both the 16S and 23S rRNA genes. In bacteria, these repeats form helical structures within the primary transcript that are recognized and cleaved by the duplex-specific endonuclease, RNaseIII. Although RNaseIII is not an essential activity in E. coli, the alternate routes for pre ...
... repeats surrounding both the 16S and 23S rRNA genes. In bacteria, these repeats form helical structures within the primary transcript that are recognized and cleaved by the duplex-specific endonuclease, RNaseIII. Although RNaseIII is not an essential activity in E. coli, the alternate routes for pre ...
Chem*3560 Lecture 10: Cyclins, cyclin kinases and cell division
... the nuclear envelope and condensation of chromosomes, which are initially in the form of replicate pairs. A series of dramatic and very visible events results in the division of the chromosome pairs , followed by orderly segregation carried out by the mitotic apparatus, so that the daughter nuclei e ...
... the nuclear envelope and condensation of chromosomes, which are initially in the form of replicate pairs. A series of dramatic and very visible events results in the division of the chromosome pairs , followed by orderly segregation carried out by the mitotic apparatus, so that the daughter nuclei e ...
Jake Wang - Critical Review of the Rosetta Algorithm
... for i+1..j-1. In fact, the optimal structure on i+1..j-1 and its score s(i+1, j-1) are independent of anything else that is built on top of it. Thus for the first scenario, S(i, j) = S(i+1, j-1) +1 since i and j can base pair. The same recursive methods apply for the other cases. In case 2, S(i,j) = ...
... for i+1..j-1. In fact, the optimal structure on i+1..j-1 and its score s(i+1, j-1) are independent of anything else that is built on top of it. Thus for the first scenario, S(i, j) = S(i+1, j-1) +1 since i and j can base pair. The same recursive methods apply for the other cases. In case 2, S(i,j) = ...
Introduction to Lab Ex. 17: Fermentation of Carbohydrates F
... The ability to ferment specific sugars is dependant on the ability of the bacterium to produce the specific enzymes required for the transport and metabolism of that particular sugar. Thus fermentation of various sugars can be used to characterize bacteria. The F-tubes use phenol red in the medium ...
... The ability to ferment specific sugars is dependant on the ability of the bacterium to produce the specific enzymes required for the transport and metabolism of that particular sugar. Thus fermentation of various sugars can be used to characterize bacteria. The F-tubes use phenol red in the medium ...
Xanthomonas campestris
... abundance in REK (61%), when compared to the control, were related to cellular metabolism (citrate cycle, glycolysis/gluconeogenesis, oxidative phosphorylation, other carbohydrate metabolism, and pentose phosphate pathway) (Supporting Information Fig. 2A). Moreover, a large number of proteins were a ...
... abundance in REK (61%), when compared to the control, were related to cellular metabolism (citrate cycle, glycolysis/gluconeogenesis, oxidative phosphorylation, other carbohydrate metabolism, and pentose phosphate pathway) (Supporting Information Fig. 2A). Moreover, a large number of proteins were a ...
Monte Carlo Simulations of HIV Capsid Protein
... offers an evaluation for the convergence of the sampling. Although the seven MC simulations were performed under different volumes, the proportion for each type of domain contacts should ideally be identical across the simulations. Indeed, the percentages (in the parentheses of Table 1) for each indiv ...
... offers an evaluation for the convergence of the sampling. Although the seven MC simulations were performed under different volumes, the proportion for each type of domain contacts should ideally be identical across the simulations. Indeed, the percentages (in the parentheses of Table 1) for each indiv ...
BIOL 504: Molecular Evolution
... 5) RNA editing: posttranslational modification can alter protein product or gene expression 6) Gene sharing ...
... 5) RNA editing: posttranslational modification can alter protein product or gene expression 6) Gene sharing ...
Genome Annotation: From Sequence to Biology
... this prediction--pardon my short sightedness. Also, has a standardized format emerged in regard to the genome files?” ...
... this prediction--pardon my short sightedness. Also, has a standardized format emerged in regard to the genome files?” ...
Do Legume Storage Proteins Play a Role in
... were responsible for at least part of the detrimental effects seen with resistant seeds (Macedo et al., 1993). This finding prompted us to investigate why vicilins isolated from TVu 2027 seeds conferred resistance to infestation by C. maculatus. We found that neither the C. maculatus-resistant seeds ...
... were responsible for at least part of the detrimental effects seen with resistant seeds (Macedo et al., 1993). This finding prompted us to investigate why vicilins isolated from TVu 2027 seeds conferred resistance to infestation by C. maculatus. We found that neither the C. maculatus-resistant seeds ...
Package `pgca`
... Author Gabriela Cohen-Freue
Maintainer Gabriela Cohen-Freue
Description Protein Group Code Algorithm (PGCA) is a computationally
inexpensive algorithm to merge protein summaries from multiple
experimental quantitative proteomics data. The algorithm
connects ...
... Author Gabriela Cohen-Freue
Molecular Mechanism of Shoot Determinacy and Flowering in
... acid signal transduction pathway (Peng et al., 1997; Silverstone et al., 1998). These two proteins and EMF1 also display homopolymeric stretches of serine residues. In addition, a region of the EMF1 protein between amino acids 901 and 1034 displays similarity (identities: 23%, positives: 37%) with t ...
... acid signal transduction pathway (Peng et al., 1997; Silverstone et al., 1998). These two proteins and EMF1 also display homopolymeric stretches of serine residues. In addition, a region of the EMF1 protein between amino acids 901 and 1034 displays similarity (identities: 23%, positives: 37%) with t ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.