![Probiotics, with special emphasis on their role in the management of](http://s1.studyres.com/store/data/014702652_1-36c8fb06c863ef878b8b578dea5e59d9-300x300.png)
Probiotics, with special emphasis on their role in the management of
... circulating inflammatory cytokines (NF-κB and TGF-β), restoring the imbalance between Th1 and Th2 responses, and an increased expression of heat-shock proteins which are essential for the maintenance of the epithelial barrier function. Through an appropriate pro- and anti-inflammatory response, the ...
... circulating inflammatory cytokines (NF-κB and TGF-β), restoring the imbalance between Th1 and Th2 responses, and an increased expression of heat-shock proteins which are essential for the maintenance of the epithelial barrier function. Through an appropriate pro- and anti-inflammatory response, the ...
The effect of acetaminophen (four grams a day for three consecutive
... the clinical laboratory of Denver Health Medical Center (Denver, CO, USA). Specimens from RCKC were assayed at Dynacare Laboratories or Quest Diagnostics (Seattle, WA, USA). Breath ethanol levels were determined at initial presentation to the treatment center, usually in the evening or early morning ...
... the clinical laboratory of Denver Health Medical Center (Denver, CO, USA). Specimens from RCKC were assayed at Dynacare Laboratories or Quest Diagnostics (Seattle, WA, USA). Breath ethanol levels were determined at initial presentation to the treatment center, usually in the evening or early morning ...
Invisalign® at Willamette Dental Group
... the orthodontist. Aligners are worn 20-22 hours each day and are removed for eating, brushing and flossing. Aligner trays are changed every two weeks through the duration of treatment. Each case is unique so the treatment duration will vary with each specific treatment plan as well as the ability of ...
... the orthodontist. Aligners are worn 20-22 hours each day and are removed for eating, brushing and flossing. Aligner trays are changed every two weeks through the duration of treatment. Each case is unique so the treatment duration will vary with each specific treatment plan as well as the ability of ...
gamunex - Grifols
... Monitoring and Laboratory Tests In some patients, administration of GAMUNEX® results in a transitory rise of passively transferred antibodies which may produce misleading serological findings such as positive direct anti-globulin and anti-HBc results in the absence of viral transmission. Periodic mo ...
... Monitoring and Laboratory Tests In some patients, administration of GAMUNEX® results in a transitory rise of passively transferred antibodies which may produce misleading serological findings such as positive direct anti-globulin and anti-HBc results in the absence of viral transmission. Periodic mo ...
Long-term effects of budesonide on ... clinical asthma severity in inhaled ...
... have similar topical potency to budesonide [12]. Subjects were required to be stable on their maintenance dose of beclomethasone dipropionate for at least 4 wks before randomization and they were also required not to have needed or taken prednisone or cromoglycate within two months of enrolment. Wom ...
... have similar topical potency to budesonide [12]. Subjects were required to be stable on their maintenance dose of beclomethasone dipropionate for at least 4 wks before randomization and they were also required not to have needed or taken prednisone or cromoglycate within two months of enrolment. Wom ...
SABRE Protocol FULL TITLE: Hypertonic Saline in Acute
... Other medications The only other permitted medications are anti-pyretics (paracetamol and/or Ibuprofen). Patients will not be allowed any drug therapy other than anti-pyretics. ...
... Other medications The only other permitted medications are anti-pyretics (paracetamol and/or Ibuprofen). Patients will not be allowed any drug therapy other than anti-pyretics. ...
Specific Immunotherapy—Indications and Mode of Action
... world, the prevalence of self-reported rhinitis symptoms now ranges from 3.2% to 66% (2). It is estimated that up to 24% of the German population suffers from allergic rhinoconjunctivitis, and 5% from allergic asthma (3). The symptoms are classified as either intermittent (present for less than four ...
... world, the prevalence of self-reported rhinitis symptoms now ranges from 3.2% to 66% (2). It is estimated that up to 24% of the German population suffers from allergic rhinoconjunctivitis, and 5% from allergic asthma (3). The symptoms are classified as either intermittent (present for less than four ...
Treatment of acute diarrhoea in adults with dioctahedral
... questionnaire is shown in Figure 1. The patients were informed that a telephone interview would also take place three days after the consultation. In the telephone interview and questionnaire, the intake of medications, time of the last diarrhoea, and the daily frequency of diarrhoea after consultat ...
... questionnaire is shown in Figure 1. The patients were informed that a telephone interview would also take place three days after the consultation. In the telephone interview and questionnaire, the intake of medications, time of the last diarrhoea, and the daily frequency of diarrhoea after consultat ...
ACTIONS final report - EU Clinical Trials Register
... No therapeutic benefit in terms of improvement in quality of life or negative symptoms was detected for citalopram over 12 weeks or at 48 weeks, but secondary analysis suggested modest improvement in the negative symptom domain, avolition/amotivation, at 12 weeks (mean difference -1.3, 95% CI 2.5 to ...
... No therapeutic benefit in terms of improvement in quality of life or negative symptoms was detected for citalopram over 12 weeks or at 48 weeks, but secondary analysis suggested modest improvement in the negative symptom domain, avolition/amotivation, at 12 weeks (mean difference -1.3, 95% CI 2.5 to ...
[Product Monograph Template - Schedule D]
... with appropriate passive immunity.13,14 Immunodeficient women who are pregnant may be at greater risk for infection since placental transfer of the IgG to the fetus may deplete already limited maternal stores.13,15 Therapeutic replacement therapy doses may in fact need to be increased to confer adeq ...
... with appropriate passive immunity.13,14 Immunodeficient women who are pregnant may be at greater risk for infection since placental transfer of the IgG to the fetus may deplete already limited maternal stores.13,15 Therapeutic replacement therapy doses may in fact need to be increased to confer adeq ...
Similar Efficacy with Omalizumab in Chronic - e
... urticaria/chronic spontaneous urticaria (CIU/CSU). Different background therapies were used in the 3 phase III clinical trials in patients with refractory CIU/CSU. What does this article add to our knowledge? Findings from this post hoc analysis indicate similar efficacy with omalizumab 300 mg in pat ...
... urticaria/chronic spontaneous urticaria (CIU/CSU). Different background therapies were used in the 3 phase III clinical trials in patients with refractory CIU/CSU. What does this article add to our knowledge? Findings from this post hoc analysis indicate similar efficacy with omalizumab 300 mg in pat ...
Double-blind, placebo-controlled study of zinc
... particularly examining the relationship between zinc and ADHD. Both animal and human study suggest that involvement of zinc deficiency plays a major role in hyperactivity (Golub et al., 1996). Human zinc deficiency syndrome leads to concentration impairment and jitters (Agget and Harries, 1979), and ...
... particularly examining the relationship between zinc and ADHD. Both animal and human study suggest that involvement of zinc deficiency plays a major role in hyperactivity (Golub et al., 1996). Human zinc deficiency syndrome leads to concentration impairment and jitters (Agget and Harries, 1979), and ...
Biologic agents in psoriasis
... tial dose followed by 1 mg/kg weekly thereafter. Treatment is of a continuous nature. In a phase III, randomized, double-blind, parallel group, placebo-controlled, multicentre, 12-week study,14 weekly subcutaneous efalizumab (1 mg/kg) improved psoriasis. Efalizumab therapy resulted in significant im ...
... tial dose followed by 1 mg/kg weekly thereafter. Treatment is of a continuous nature. In a phase III, randomized, double-blind, parallel group, placebo-controlled, multicentre, 12-week study,14 weekly subcutaneous efalizumab (1 mg/kg) improved psoriasis. Efalizumab therapy resulted in significant im ...
. # 0 &
... until normal function is restored. h may also be given by mouth in a dose of 5 mg daily thirty minutes before breakfast. A similar dose by mouth. given daily or on alremale days, has been employed in the managemem of ...
... until normal function is restored. h may also be given by mouth in a dose of 5 mg daily thirty minutes before breakfast. A similar dose by mouth. given daily or on alremale days, has been employed in the managemem of ...
1 - NICE
... As the Butler and Heron study reported prevalence of wetting at several different time points, we had to choose a specific time point from which to generate a baseline risk. Because the average population across the trials is between 8 and 10 years, we decided to base the baseline risk of becoming d ...
... As the Butler and Heron study reported prevalence of wetting at several different time points, we had to choose a specific time point from which to generate a baseline risk. Because the average population across the trials is between 8 and 10 years, we decided to base the baseline risk of becoming d ...
Orthodontic Treatment Needs in the Western Region of Saudi Arabia
... treatment [1]. In Saudi Arabia, governmental sectors provide free orthodontic treatment for people, which has generated long waiting lists of patients that extend for two to four years. Evaluation of self perceived and actual need for orthodontic treatment as well as other factors affecting these ne ...
... treatment [1]. In Saudi Arabia, governmental sectors provide free orthodontic treatment for people, which has generated long waiting lists of patients that extend for two to four years. Evaluation of self perceived and actual need for orthodontic treatment as well as other factors affecting these ne ...
Respiratory medicines for children: current evidence, unlicensed use and research priorities
... young children (aged 2–5 yrs) with multiple-trigger wheeze, montelukast improved symptoms and achieved a 30% reduction in exacerbations [33]. There are no studies in this age group comparing montelukast with ICS. Montelukast in episodic (viral) wheeze Daily use of montelukast over a 1-yr period redu ...
... young children (aged 2–5 yrs) with multiple-trigger wheeze, montelukast improved symptoms and achieved a 30% reduction in exacerbations [33]. There are no studies in this age group comparing montelukast with ICS. Montelukast in episodic (viral) wheeze Daily use of montelukast over a 1-yr period redu ...
management and Prevention of hereditary Angioedema Attacks
... end point, was more than halved in the Cinryze arm compared with placebo (2 hours vs more than 4 hours; P = .02).16 In an open-label extension part of the trial, the median time to response was 30 minutes among 82 patients who experienced 447 separate attacks.16 Ecallantide (Kalbitor). Ecallantide i ...
... end point, was more than halved in the Cinryze arm compared with placebo (2 hours vs more than 4 hours; P = .02).16 In an open-label extension part of the trial, the median time to response was 30 minutes among 82 patients who experienced 447 separate attacks.16 Ecallantide (Kalbitor). Ecallantide i ...
Orthodontic Treatment Need in Dubai School Adolescents: A Study
... Malocclusion is a common oral disorder which manifests itself during childhood, and the correction of malocclusion vis-à-vis orthodontic treatment is frequently carried out during childhood. With the growing demand for orthodontic treatment, a variety of clinician based indices have been developed t ...
... Malocclusion is a common oral disorder which manifests itself during childhood, and the correction of malocclusion vis-à-vis orthodontic treatment is frequently carried out during childhood. With the growing demand for orthodontic treatment, a variety of clinician based indices have been developed t ...
Adventures in Rhinorrhea
... Oral steroids also possibly beneficial but studies mixed – Seems more useful if nasal polyps present ...
... Oral steroids also possibly beneficial but studies mixed – Seems more useful if nasal polyps present ...
PUrE protocol V01 25 January 2016 (01 25 Jan 2016)
... We will require 1044 (522 in each of RCT1 and RCT2) eligible patients to consent to participate in the study after considering written and spoken information provided by local clinical and research teams. Eligible and consenting participants, who have a CTKUB to confirm the presence and size of ston ...
... We will require 1044 (522 in each of RCT1 and RCT2) eligible patients to consent to participate in the study after considering written and spoken information provided by local clinical and research teams. Eligible and consenting participants, who have a CTKUB to confirm the presence and size of ston ...
The following protocol information is provided solely to describe how... research underlying the published report associated with the following article:
... The information provided may not reflect the complete protocol or any previous amendments or modifications. As described in the Information for Contributors (http://jco.ascopubs.org/site/ifc/protocol.xhtml) only specific elements of the most recent version of the protocol are requested by JCO. The p ...
... The information provided may not reflect the complete protocol or any previous amendments or modifications. As described in the Information for Contributors (http://jco.ascopubs.org/site/ifc/protocol.xhtml) only specific elements of the most recent version of the protocol are requested by JCO. The p ...
Pediatric Gastroenteritis: Is That IV Really Necessary?
... MMWR Recommendations and Reports, November 21, 2003. ...
... MMWR Recommendations and Reports, November 21, 2003. ...
Reporting Of Results In Clinicaltrials.gov And High
... information to reach the prescribing clinician decision-makers and professional organizations creating clinical guidelines, all clinical trial results would be published completely and accurately in the medical literature.8 Unfortunately, however, a growing body of literature has indicated this is r ...
... information to reach the prescribing clinician decision-makers and professional organizations creating clinical guidelines, all clinical trial results would be published completely and accurately in the medical literature.8 Unfortunately, however, a growing body of literature has indicated this is r ...
Prescribing Information
... spasticity/dystonia, muscle mass, body weight, and response to any previous botulinum toxin injections. The frequency of XEOMIN repeat treatments should be determined by clinical response, but should generally be no more frequent than every 12 weeks [see Clinical Studies (14.2)]. 2.4 Blepharospasm T ...
... spasticity/dystonia, muscle mass, body weight, and response to any previous botulinum toxin injections. The frequency of XEOMIN repeat treatments should be determined by clinical response, but should generally be no more frequent than every 12 weeks [see Clinical Studies (14.2)]. 2.4 Blepharospasm T ...
Placebo-controlled study
![](https://commons.wikimedia.org/wiki/Special:FilePath/Cebocap.jpg?width=300)
Placebo-controlled studies are a way of testing a medical therapy in which, in addition to a group of subjects that receives the treatment to be evaluated, a separate control group receives a sham ""placebo"" treatment which is specifically designed to have no real effect. Placebos are most commonly used in blinded trials, where subjects do not know whether they are receiving real or placebo treatment. Often, there is also a further ""natural history"" group that does not receive any treatment at all.The purpose of the placebo group is to account for the placebo effect, that is, effects from treatment that do not depend on the treatment itself. Such factors include knowing one is receiving a treatment, attention from health care professionals, and the expectations of a treatment's effectiveness by those running the research study. Without a placebo group to compare against, it is not possible to know whether the treatment itself had any effect.Patients frequently show improvement even when given a sham or ""fake"" treatment. Such intentionally inert placebo treatments can take many forms, such as a pill containing only sugar, a surgery where nothing efficacious is actually done (just an incision and sometimes some minor touching or handling of the underlying structures), or a medical device (such as an ultrasound machine) that is not actually turned on. Also, due to the body's natural healing ability and statistical effects such as regression to the mean, many patients will get better even when given no treatment at all. Thus, the relevant question when assessing a treatment is not ""does the treatment work?"" but ""does the treatment work better than a placebo treatment, or no treatment at all?"" As one early clinical trial researcher wrote, ""the first object of a therapeutic trial is to discover whether the patients who receive the treatment under investigation are cured more rapidly, more completely or more frequently, than they would have been without it.""p.195 More broadly, the aim of a clinical trial is to determine what treatments, delivered in what circumstances, to which patients, in what conditions, are the most effective.Therefore, the use of placebos is a standard control component of most clinical trials, which attempt to make some sort of quantitative assessment of the efficacy of medicinal drugs or treatments. Such a test or clinical trial is called a placebo-controlled study, and its control is of the negative type. A study whose control is a previously tested treatment, rather than no treatment, is called a positive-control study, because its control is of the positive type.Government regulatory agencies approve new drugs only after tests establish not only that patients respond to them, but also that their effect is greater than that of a placebo (by way of affecting more patients, by affecting responders more strongly, or both). As a result, ""placebo-controlled studies often are designed in such a way that disadvantages the placebo condition"".