EFFECT OF ASCORBIC ACID CONCENTRATION ON
... Ascorbic acid effect plant growth and increased activity of apical meristem. This increase in growth may due to include from increase in mitotic division in meristematic zones and cell growth in length due to ascorbic acid influence [Smirnoff et al. 2000]. Obtained results confirmed that ascorbic ac ...
... Ascorbic acid effect plant growth and increased activity of apical meristem. This increase in growth may due to include from increase in mitotic division in meristematic zones and cell growth in length due to ascorbic acid influence [Smirnoff et al. 2000]. Obtained results confirmed that ascorbic ac ...
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... the modulation of dendritic cells (DCs), which are key regulatory players of the adaptive immune response [8]. Our previous work showed that TsSP induce Th2 responses via DCs, whereas the induction of Th1 and Th17 responses by TsSP-primed human DCs is strongly reduced [7, 9]. Beside affecting adapti ...
... the modulation of dendritic cells (DCs), which are key regulatory players of the adaptive immune response [8]. Our previous work showed that TsSP induce Th2 responses via DCs, whereas the induction of Th1 and Th17 responses by TsSP-primed human DCs is strongly reduced [7, 9]. Beside affecting adapti ...
COMMUNICATION Two categories of mammalian galactose
... (glycan 161), but the nonfucosylated form (glycan 101) also binds well to RHL-1. Unfortunately, more branched triand tetra-antennary glycans that have been shown to compete particularly effectively for binding to the asialoglycoprotein receptor (Lee et al., 1983) are not present on the array. Finall ...
... (glycan 161), but the nonfucosylated form (glycan 101) also binds well to RHL-1. Unfortunately, more branched triand tetra-antennary glycans that have been shown to compete particularly effectively for binding to the asialoglycoprotein receptor (Lee et al., 1983) are not present on the array. Finall ...
Bile acids in regulation of inflammation and immunity: friend or foe?
... leading to hepatocyte death. ROS released by neutrophils have been further shown to contribute to liver sinusoidal endothelial cell damage in cholestasis (28). Some BAs, such as lithocholic acid (LCA), which is elevated in cholestasis, are suggested to stimulate neutrophils and thus to increase form ...
... leading to hepatocyte death. ROS released by neutrophils have been further shown to contribute to liver sinusoidal endothelial cell damage in cholestasis (28). Some BAs, such as lithocholic acid (LCA), which is elevated in cholestasis, are suggested to stimulate neutrophils and thus to increase form ...
Human granulocyte-macrophage colony
... myeloid cells and endothelial cells70. External stimuli such as antigens and endotoxins influence increased GM-CSF production. GM-CSF Receptor (GMR) The hGM-CSF is found to have a broad range of effects on several different types of cells, which include monocytes, megakaryocytes, eosinophils, blast ...
... myeloid cells and endothelial cells70. External stimuli such as antigens and endotoxins influence increased GM-CSF production. GM-CSF Receptor (GMR) The hGM-CSF is found to have a broad range of effects on several different types of cells, which include monocytes, megakaryocytes, eosinophils, blast ...
Bacterial short chain fatty acid metabolites modulate the
... Short‐chain fatty acids (SCFAs) impair the killing of Aggregatibacter actinomycetemcomitans in vivo. The exudate collected after 4 (a) or 24 hr (b) of A. actinomycetemcomitans inoculation in the chamber was diluted and plated in brain heart infusion chocolate agar. Bacterial colonies were counted, a ...
... Short‐chain fatty acids (SCFAs) impair the killing of Aggregatibacter actinomycetemcomitans in vivo. The exudate collected after 4 (a) or 24 hr (b) of A. actinomycetemcomitans inoculation in the chamber was diluted and plated in brain heart infusion chocolate agar. Bacterial colonies were counted, a ...
Role of histamine in controlling gastric acid secretion
... Histamine in an amino acid derivative , it formed continually in small amount in gastric mucosa,either in response to acid in the stomach or for other reasons , this amount , acting by itself ,causes little acid secretion , however , whenever Ach , & gastrine stimulate the pariatal cells at the same ...
... Histamine in an amino acid derivative , it formed continually in small amount in gastric mucosa,either in response to acid in the stomach or for other reasons , this amount , acting by itself ,causes little acid secretion , however , whenever Ach , & gastrine stimulate the pariatal cells at the same ...
Review Article - clinicalevidence
... PepG, the main component of the gram-positive bacterial cell wall, is a heteropolymer consisting of a glycan backbone of alternating units of N-acetyl-glucosamine and N-acetylmuramic acid, with short peptides linked to the lactyl groups of the muramic acid moieties (Fig. 1). During gram-positive bac ...
... PepG, the main component of the gram-positive bacterial cell wall, is a heteropolymer consisting of a glycan backbone of alternating units of N-acetyl-glucosamine and N-acetylmuramic acid, with short peptides linked to the lactyl groups of the muramic acid moieties (Fig. 1). During gram-positive bac ...
Antiangiogenic Effect of Ficus deltoidea Jack Standardised Leaf
... Institute (NCI) extracts with IC50 >20 µg mL-1 are not considered cytotoxic [19]. However, the extracts showed higher cytotoxicity towards the colon cancer (HCT 116) and breast cancer (MDA-MB-231) cells. In order to illustrate the antiangiogenic potential of FD in vivo, the extracts were tested on c ...
... Institute (NCI) extracts with IC50 >20 µg mL-1 are not considered cytotoxic [19]. However, the extracts showed higher cytotoxicity towards the colon cancer (HCT 116) and breast cancer (MDA-MB-231) cells. In order to illustrate the antiangiogenic potential of FD in vivo, the extracts were tested on c ...
Membrane receptors in the gastrointestinal tract
... to inositol phospholipid hydrolysis in guinea pig gastric glands (24). Membrane receptors coupled to G proteins possess an extracellular domain with a consensus site for N-linked glycosylation at the amino terminus, seven membrane spanning domains and cytoplasmic regions involved in recognition and ...
... to inositol phospholipid hydrolysis in guinea pig gastric glands (24). Membrane receptors coupled to G proteins possess an extracellular domain with a consensus site for N-linked glycosylation at the amino terminus, seven membrane spanning domains and cytoplasmic regions involved in recognition and ...
Production of macrophage activating factors by the mitogen
... supernatants were collected. Thyoglycolate induced, allogenic, peritoneal macrophages were incubated with or without stimulated cell supernatants. Then, the phagocytic activity against inactivated yeast and peroxidase production were measured. Stimulated cell supernatants increased the phagocytic ac ...
... supernatants were collected. Thyoglycolate induced, allogenic, peritoneal macrophages were incubated with or without stimulated cell supernatants. Then, the phagocytic activity against inactivated yeast and peroxidase production were measured. Stimulated cell supernatants increased the phagocytic ac ...
Neutrophils in tuberculosis
... in liver within 2 hours of systemic challenge with M.avium [12]. There is skin infiltration of neutrophils within 3 hours of BCG infection in rabbits [13]. In case of mice it takes 4 hours for skin infiltration with the same challenge study as that of rabbit [14]. Mechanism of recruitment: In sensit ...
... in liver within 2 hours of systemic challenge with M.avium [12]. There is skin infiltration of neutrophils within 3 hours of BCG infection in rabbits [13]. In case of mice it takes 4 hours for skin infiltration with the same challenge study as that of rabbit [14]. Mechanism of recruitment: In sensit ...
MINI-SERIES ‘‘T-CELL CO-STIMULATORY MOLECULES’’ Edited by M. Belvisi and K.F. Rabe
... cytokines, such as IL-4, -5 and -13, has been demonstrated by a large body of evidence. The important role of the various Th2 cytokines in the development of allergic airway inflammation was further demonstrated by analysis of the pathology of mice overexpressing certain Th2 cytokines, by use of cyt ...
... cytokines, such as IL-4, -5 and -13, has been demonstrated by a large body of evidence. The important role of the various Th2 cytokines in the development of allergic airway inflammation was further demonstrated by analysis of the pathology of mice overexpressing certain Th2 cytokines, by use of cyt ...
Neutrophils diminish T-cell immunity to foster gastric cancer
... tumour cells by releasing antimicrobial and cytotoxic contents that are prestored in their granules. Neutrophils can induce apoptosis in tumour cells and reduce tumour growth when administrated into tumour-bearing animals. Neutrophils are regarded as important effector cells for monoclonal antibody ...
... tumour cells by releasing antimicrobial and cytotoxic contents that are prestored in their granules. Neutrophils can induce apoptosis in tumour cells and reduce tumour growth when administrated into tumour-bearing animals. Neutrophils are regarded as important effector cells for monoclonal antibody ...
Relevance of granulocyte apoptosis to resolution of
... to combat helminthic infection. Increasingly, new roles for eosinophils are being identified and it seems likely that they have a role in combating viral infection as eosinophil cationic protein and eosinophil-derived neurotoxin have been shown to degrade single-stranded RNA viruses. They are said t ...
... to combat helminthic infection. Increasingly, new roles for eosinophils are being identified and it seems likely that they have a role in combating viral infection as eosinophil cationic protein and eosinophil-derived neurotoxin have been shown to degrade single-stranded RNA viruses. They are said t ...
Toll-like receptors as therapeutic targets in cystic fibrosis.
... role in the antiviral response [29,30]. Their major agonists are guanosine- and uridine-rich single-stranded (ss)RNA found in many viruses [31,32]. Microbial DNA featuring unmethylated CpG (uCpG) dinucleotides motifs activate TLR9 [33]. These occur frequently in bacterial but not mammalian DNA. Flag ...
... role in the antiviral response [29,30]. Their major agonists are guanosine- and uridine-rich single-stranded (ss)RNA found in many viruses [31,32]. Microbial DNA featuring unmethylated CpG (uCpG) dinucleotides motifs activate TLR9 [33]. These occur frequently in bacterial but not mammalian DNA. Flag ...
Fc receptors: Cell activators of antibody functions
... with low production of this class of antibodies, in which there is increased susceptibility to microbial infections [4]. Although, IgG antibodies are essential for controlling infections, these molecules do not directly damage the microorganisms they recognize. Today, it is established that leukocyt ...
... with low production of this class of antibodies, in which there is increased susceptibility to microbial infections [4]. Although, IgG antibodies are essential for controlling infections, these molecules do not directly damage the microorganisms they recognize. Today, it is established that leukocyt ...
Murine Effector Cells Crosstalk between Human IgG Isotypes and
... system in patients. Humanization had as a consequence that efficacy studies performed in mouse models, which represent a crucial step in preclinical development, are more difficult to interpret because of gaps in our knowledge of the activation of murine effector cells by human IgG (hIgG) remain. We ...
... system in patients. Humanization had as a consequence that efficacy studies performed in mouse models, which represent a crucial step in preclinical development, are more difficult to interpret because of gaps in our knowledge of the activation of murine effector cells by human IgG (hIgG) remain. We ...
Acute lung injury: how the lung inflammatory response works P.A. Ward
... Products of the acute inflammatory response in lung causing tissue injury are released from recruited PMN and activated lung macrophages [4]. These include toxin oxygen (O2, hydrogen peroxide, etc.) and nitrogen (nitrosyl, peroxynitrite, etc.) products, together with proteases released from these ph ...
... Products of the acute inflammatory response in lung causing tissue injury are released from recruited PMN and activated lung macrophages [4]. These include toxin oxygen (O2, hydrogen peroxide, etc.) and nitrogen (nitrosyl, peroxynitrite, etc.) products, together with proteases released from these ph ...
Wolbachia bacteria in filarial immunity and disease
... of lymphatic endothelia (53) are elevated in lymph from parasitized lymphatics (54). The activation of lymphatic endothelium may be important in controlling the composition and pressure of interstitial fluid and in facilitating lymphocyte trafficking and thus have an important role in inflammatory p ...
... of lymphatic endothelia (53) are elevated in lymph from parasitized lymphatics (54). The activation of lymphatic endothelium may be important in controlling the composition and pressure of interstitial fluid and in facilitating lymphocyte trafficking and thus have an important role in inflammatory p ...
Neutrophils in the innate immune response
... a human pathogen that employs several novel mechanisms to circumvent destruction by neutrophils (reviewed by Voyich et al.195). For example, S. pyogenes produces a 130-kDa serine endopeptidase aptly called C5a peptidase that specifically cleaves the complement chemoattractant C5a to inhibit PMN recr ...
... a human pathogen that employs several novel mechanisms to circumvent destruction by neutrophils (reviewed by Voyich et al.195). For example, S. pyogenes produces a 130-kDa serine endopeptidase aptly called C5a peptidase that specifically cleaves the complement chemoattractant C5a to inhibit PMN recr ...
Expression and transcriptional activity of progesterone receptor A
... one PR isoform, usually PRA, is seen in cancers, suggests that disrupted progesterone signaling may play a role in development or progression of breast cancer. ...
... one PR isoform, usually PRA, is seen in cancers, suggests that disrupted progesterone signaling may play a role in development or progression of breast cancer. ...
Cloning, Expression, and Pharmacological Characterization of a
... tissues likely to contain high concentrations of blood cells, such as bone marrow and lung. In situ hybridization analysis of a wide survey of mouse tissues showed that mouse AXOR35 mRNA is selectively expressed in hippocampus. The identification and localization of this new histamine receptor will ...
... tissues likely to contain high concentrations of blood cells, such as bone marrow and lung. In situ hybridization analysis of a wide survey of mouse tissues showed that mouse AXOR35 mRNA is selectively expressed in hippocampus. The identification and localization of this new histamine receptor will ...
SALVIA Research Article JIJA MATHEW* AND JOHN E. THOPPIL
... genoprotective efficacy of methanol extracts of Salvia farinacea Benth., Salvia microphylla Kunth and Salvia splendens Sellow ex J. A. Schult. ‘Blue Ribbon’ (Lamiaceae) against the methyl parathion-induced toxicity on bone marrow cells and spermatocytes of Swiss albino mice by chromosomal aberration ...
... genoprotective efficacy of methanol extracts of Salvia farinacea Benth., Salvia microphylla Kunth and Salvia splendens Sellow ex J. A. Schult. ‘Blue Ribbon’ (Lamiaceae) against the methyl parathion-induced toxicity on bone marrow cells and spermatocytes of Swiss albino mice by chromosomal aberration ...
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... Leukotrienes (LTs) are biologically active arachidonic acid (AA) derivatives generated by the 5-‐lipoxygenase (5-‐LO) pathway. They are produced by myeloid cells. 5-‐LO converts AA to LTA4 in cooperation with ...
... Leukotrienes (LTs) are biologically active arachidonic acid (AA) derivatives generated by the 5-‐lipoxygenase (5-‐LO) pathway. They are produced by myeloid cells. 5-‐LO converts AA to LTA4 in cooperation with ...