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Principles of Metabolic Regulation
Principles of Metabolic Regulation

... • The biochemical reactions in the living cell — the metabolism — is organized into metabolic pathways • The pathways have dedicated purposes – Some are dedicated to extraction of energy – Some are dedicated to storage of fuels ...
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... substitutions that alters property 1 (Rumer, 1966). The substitutions exchanging T and G as well as A and C are applied to all three codon bases and are called Rumer’s transformation. If the third base is necessary to define an amino acid, then the symmetrical codon by Rumer’s transformation does not ...
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... FIGURE 17-1: The formation of glutamate from α-ketoglutarate, a TCA cycle intermediate. α-ketoglutarate, which is formed from glucose, constitutes the carbon backbone of glutamate. The amino group derives from another amino acid, which after donation of its amino group becomes a keto acid or an ald ...
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molecular biology
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polyribosomes
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Diversity of Metabolism in Procaryotes
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Amino Acids - Building Blocks of Proteins
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Energetics and Catabolism
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doc BIOL 200 Notes up to Midterm
doc BIOL 200 Notes up to Midterm

... o Pyrimidines: cytosine, thymine (DNA), uracil (RNA), aromatic ring that involves 6 atoms o Phosphodiester linkage links 3’ hydroxyl group to 5’ hydroxyl group: sugar phosphate backbone o Most RNAs have <100 to 10,000 nucleotides o Cellular DNA molecules can be 100,000,000 nucleotides long o 5’ end ...
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MBLG1001 Lecture 9 The Flow of Genetic Information Replication
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... • The larger fragment is the Klenow enzyme. It is very useful as a DNA polymerase. • It requires a primer (needs a 3’OH to add the next nucleotide to). • It is very good a copying DNA. • It can be used to synthesise a labeled strand of DNA for experiments ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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