Poster
... expensive tissues such as the brain and liver, ultimately causing death in early infancy. Deoxyguanosine kinase (dGK), an enzymatic protein, plays a role in regulation of mtDNA by attaching a phosphate to a sugar/nitrogen-base nucleoside. Once phosphorylated, the assembly of mtDNA proceeds. Mutation ...
... expensive tissues such as the brain and liver, ultimately causing death in early infancy. Deoxyguanosine kinase (dGK), an enzymatic protein, plays a role in regulation of mtDNA by attaching a phosphate to a sugar/nitrogen-base nucleoside. Once phosphorylated, the assembly of mtDNA proceeds. Mutation ...
Sample questions from old exam I BCHS 3304 – Dr. Yeo T
... Sample questions from old exam I BCHS 3304 – Dr. Yeo I. True or False (#1 to 5)? ...
... Sample questions from old exam I BCHS 3304 – Dr. Yeo I. True or False (#1 to 5)? ...
Chapter - I 1 1.1. Introduction to amino acids
... characteristic structure. With the exception of proline, all twenty amino acids have an amino group and a carboxyl group with a functional group covalently bound to the alpha carbon. In the essential amino acids, the functional groups are used to classify the amino acids into polar, non-polar, or ba ...
... characteristic structure. With the exception of proline, all twenty amino acids have an amino group and a carboxyl group with a functional group covalently bound to the alpha carbon. In the essential amino acids, the functional groups are used to classify the amino acids into polar, non-polar, or ba ...
Chapter 27-28 - Bakersfield College
... Hydrolysis of Succinyl CoA - Energy from hydrolysis of succinyl CoA is used to add a phosphate group (Pi) to GDP (guanosine diphosphate). - The hydrolysis of GTP is used to add a Pi to ADP to produce ATP. GTP + ADP → GDP+ ATP ...
... Hydrolysis of Succinyl CoA - Energy from hydrolysis of succinyl CoA is used to add a phosphate group (Pi) to GDP (guanosine diphosphate). - The hydrolysis of GTP is used to add a Pi to ADP to produce ATP. GTP + ADP → GDP+ ATP ...
File - western undergrad. by the students, for the students.
... protein held together via protein-protein interactions. ...
... protein held together via protein-protein interactions. ...
Use of Amino Acid-Nucleotide Base Pair Potentials in Screening
... repair [1]. Since DNA play very important roles in cells, they are molecular targets of many clinically used drugs, such as anticancer drugs and antibiotics [2]. Study on the protein-DNA interactions would be meaningful for drugs design on the nucleic acids. However, the determination of the protein ...
... repair [1]. Since DNA play very important roles in cells, they are molecular targets of many clinically used drugs, such as anticancer drugs and antibiotics [2]. Study on the protein-DNA interactions would be meaningful for drugs design on the nucleic acids. However, the determination of the protein ...
Inquiry into Life Twelfth Edition
... (active) where phosphodiester bonds form – E and A sites partially overlap – Rotation of nucleotide between the E and A sites may play a role in base and sugar specificity ...
... (active) where phosphodiester bonds form – E and A sites partially overlap – Rotation of nucleotide between the E and A sites may play a role in base and sugar specificity ...
Chymotrypsin
... pocket, but lacks a functional oxyanion hole, which stabilizes the transition state. This is yet another example of the critical importance of transition state stabilization as the primary factor explaining the catalytic activity of enzymes. ...
... pocket, but lacks a functional oxyanion hole, which stabilizes the transition state. This is yet another example of the critical importance of transition state stabilization as the primary factor explaining the catalytic activity of enzymes. ...
Case Study #1 Use of bioinformatics in drug development
... •Inhibitors are designed to bind with higher affinity: their affinities often exceed the corresponding substrate affinities by several orders of magnitude! •Agonists are analogous to enzyme substrates: part of the binding energy may be used for signal transduction, inducing a conformation or aggrega ...
... •Inhibitors are designed to bind with higher affinity: their affinities often exceed the corresponding substrate affinities by several orders of magnitude! •Agonists are analogous to enzyme substrates: part of the binding energy may be used for signal transduction, inducing a conformation or aggrega ...
The complete nucleotide sequence of cucumber green mottle
... that of another CGMMV isolate (CGMMV-W) (Meshi et al., 1983b; Saito et al., 1988). The coat protein gene of our CGMMV isolate was also found to be composed of the same number of nucleotides as that found in CGMMV-W (Meshi et al., 1983b). In total, 27 nucleotide substitutions (six in the 186K protein ...
... that of another CGMMV isolate (CGMMV-W) (Meshi et al., 1983b; Saito et al., 1988). The coat protein gene of our CGMMV isolate was also found to be composed of the same number of nucleotides as that found in CGMMV-W (Meshi et al., 1983b). In total, 27 nucleotide substitutions (six in the 186K protein ...
Enzymes speed up metabolic reactions by lowering energy barriers
... polymerase (used in replication of DNA) ...
... polymerase (used in replication of DNA) ...
determining evolutionary relationships using
... protein biology two organisms share, the more time has elapsed between the two organisms' divergence from a common ancestor. We would also expect two organisms that share a high level of protein similarity to have similar anatomical features and be closely linked phylogenetically. Using the process ...
... protein biology two organisms share, the more time has elapsed between the two organisms' divergence from a common ancestor. We would also expect two organisms that share a high level of protein similarity to have similar anatomical features and be closely linked phylogenetically. Using the process ...
Continued..
... Motif can refer to a set of contiguous secondary structure elements that either have a particular functional significance or define a portion of an independently folded domain. The elements with the functional sequence motifs are known as functional motifs. An example is the helix-turn-helix mot ...
... Motif can refer to a set of contiguous secondary structure elements that either have a particular functional significance or define a portion of an independently folded domain. The elements with the functional sequence motifs are known as functional motifs. An example is the helix-turn-helix mot ...
8.4 Transcription
... • Prokaryotic cells: replication, transcription, and translation all occur in the cytoplasm (remember there is no nucleus), at approx the same time • In Eukaryotic cells, where DNA is located inside the nucleus, these processes are separated by location and times. – Replication and transcription occ ...
... • Prokaryotic cells: replication, transcription, and translation all occur in the cytoplasm (remember there is no nucleus), at approx the same time • In Eukaryotic cells, where DNA is located inside the nucleus, these processes are separated by location and times. – Replication and transcription occ ...
Exam #3 2 Problem 1. (25 points) You study ligand binding to two
... (2) binding of O2 to the T state shifts the equilibrium towards the R state: [T] / [R] > [T(O2)] / [R(O2)] , hence L > L’. 2. CO2, H+, and BPG all act as heterotropic allosteric effectors for this process. Which of these four constants (if any) are affected by the presence of these compounds? These ...
... (2) binding of O2 to the T state shifts the equilibrium towards the R state: [T] / [R] > [T(O2)] / [R(O2)] , hence L > L’. 2. CO2, H+, and BPG all act as heterotropic allosteric effectors for this process. Which of these four constants (if any) are affected by the presence of these compounds? These ...
Transamination Governs Nitrogen Isotope Heterogeneity of Amino
... alanine, aspartic acid, and glutamic acid (among others) reflect a similar trophic position as bulk tissues, whereas glycine and phenylalanine provide an accurate determination of the δ15N at the base of the food web,2,7 although reasons for this grouping, as well as the information that can be obtai ...
... alanine, aspartic acid, and glutamic acid (among others) reflect a similar trophic position as bulk tissues, whereas glycine and phenylalanine provide an accurate determination of the δ15N at the base of the food web,2,7 although reasons for this grouping, as well as the information that can be obtai ...
Systemic Response to Injury and Metabolic Support
... Urinary nitrogen approx 2-5g/day Reflects change to using ketone bodies as energy source Brain begins to use ketones as energy source after 2 days, and this becomes the principal energy source by 24 days ...
... Urinary nitrogen approx 2-5g/day Reflects change to using ketone bodies as energy source Brain begins to use ketones as energy source after 2 days, and this becomes the principal energy source by 24 days ...
Utilization of FIA-UV/ED for detection of adenine derivates
... A purine derivative adenine poses many biological functions. Besides the fact that this molecule is one of the building blocks for RNA and DNA, there are many derivates with their specifics attributes. 2-aminopurine is well known as mutagen. 2,6diaminopurine is able to replace purine basis in nuclei ...
... A purine derivative adenine poses many biological functions. Besides the fact that this molecule is one of the building blocks for RNA and DNA, there are many derivates with their specifics attributes. 2-aminopurine is well known as mutagen. 2,6diaminopurine is able to replace purine basis in nuclei ...
secstruct_and_sign_pep_PT
... An amino acid has several structural components: a central carbon atom (Ca), an amino group (NH2), a carboxyl group (COOH), a hydrogen atom (H), a side chain (R). There are 20 amino acids The peptide bond is formed as the cacboxyl group of an aa bind to the amino group of the adjacent aa. The primar ...
... An amino acid has several structural components: a central carbon atom (Ca), an amino group (NH2), a carboxyl group (COOH), a hydrogen atom (H), a side chain (R). There are 20 amino acids The peptide bond is formed as the cacboxyl group of an aa bind to the amino group of the adjacent aa. The primar ...
Biosynthesis
Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.