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Lecture 27
Lecture 27

... Gln is an amino donor for many biosynthetic products and also a storage compound for excess ammonia. Mammalian glutamine synthetase is activated by ketoglutarate. Bacterial glutamine synthetase has more complicated ...
Biocatalysis - School of Chemical Sciences
Biocatalysis - School of Chemical Sciences

... conditions, are also very attractive in commercial applications. The characteristics of limited operating regions, substrate or product inhibition, and reactions in aqueous solutions have often been considered as the most serious drawbacks of biocatalysts. Many of these drawbacks, however, turn out ...
How does Information get out of the Nucleus
How does Information get out of the Nucleus

... For each kind of tRNA, there is a specific enzyme which binds to it and to the amino acid that goes on it, and bonds them together. These synthetase enzymes control what amino acid each codon will stand for; they determine the genetic code. It's important to note that the groups where the tRNA and a ...
Protein foods - Deans Community High School
Protein foods - Deans Community High School

... Our bodies need certain amino acids to keep us healthy. We get these amino acids by eating protein in animal and plant foods. We have the same problem with eating protein as we do with eating starch. Protein molecules are too big to get into our blood. This means that our bodies have to break the pr ...
Chapter 8
Chapter 8

... My friend NADH, Let your electrons take the steps down. Slowly, but surely ...
THINK-PAIR
THINK-PAIR

... • Explain how various animals resolve transport of materials. Point out an advantage and disadvantage of each. • Explain how oxygen is transported in the blood. Point out two different changes that can help the easy release of oxygen in the right places. • Describe three evolutionary trends of vert ...
Biol 1406 notes Ch 9 8thed
Biol 1406 notes Ch 9 8thed

... To perform their many tasks, living cells require energy from outside sources. Energy enters most ecosystems as sunlight and leaves as heat. In contrast, the chemical elements essential for life are recyled. Photosynthesis generates oxygen and organic molecules that the mitochondria of eukaryotes (i ...
Proliferation Metabolic Pathway Alterations that Support Cell
Proliferation Metabolic Pathway Alterations that Support Cell

... (Figs. 4 and 5) (Lehninger et al. 1993). Four isoforms of pyruvate kinase are present in mammals, and the M2 isoform (PKM2) is the isoform expressed in both cancer cells and normal proliferating cells (Mazurek 2010). PKM2 is a product of the PK-M gene, which is alternatively spliced by differential ...
Metabolic flux rewiring in mammalian cell cultures
Metabolic flux rewiring in mammalian cell cultures

Genetic encoding of the post-translational modification 2
Genetic encoding of the post-translational modification 2

... The synthesis of Khib was performed from lysine by first preparing a copper complex, which allows for selective acylation of the ε-nitrogen (Scheme 1). This complex was then treated with 2-hydroxyisobutyryl-O-succinimide ester and the copper was removed by a chelating agent to generate the final pro ...
395
395

...  maltose------glucose and glucose malt sugar  must be digested to their smaller units to be absorbed into blood  this is hydrolysis…adding water allows the bonds to break between each unit Polysaccharides  long chains of simple sugars linked together  insoluble, ideal storage molecules, ex. st ...
BME205H1_20171_621493426054BME205
BME205H1_20171_621493426054BME205

TRANSLASI - alanindra
TRANSLASI - alanindra

... • New polypeptides usually fold themselves spontaneously into their active conformation. However, some proteins are helped and guided in the folding process by chaperone proteins • Many proteins have sugars, phosphate groups, fatty acids, and other molecules covalently attached to certain amino acid ...
L20_StvnWAT
L20_StvnWAT

... • BUT liver can do b-oxidation on FA even if there is no need for ATP – In the liver, CoA can be regenerated in a pathway other than the Krebs cycle ...
energy - De Anza College
energy - De Anza College

... o when temp ↑, the shape of the enzyme changes due to unfolding of the protein chains o optimal pH range o most enzymes work best within pH range of 6 – 8 o exceptions are stomach enzymes that function in acidic ranges ...
The Point is to Make ATP!
The Point is to Make ATP!

...  C6H12O6  CO2 = fuel has been oxidized  electrons attracted to more electronegative atoms  in biology, the most electronegative atom? ...
The Point is to Make ATP!
The Point is to Make ATP!

...  C6H12O6  CO2 = fuel has been oxidized  electrons attracted to more electronegative atoms  in biology, the most electronegative atom? ...
Name ________________________________________ Date __________________ Class Period___________________________________
Name ________________________________________ Date __________________ Class Period___________________________________

... 5. Why do oxygen molecules pass freely through a cell membrane, while glucose molecules do not? Topic 3: Osmosis 1. What is the process of osmosis? 2. How is osmosis important to the maintenance of homeostasis in cells? 3. Under what conditions is a cell in osmotic balance? 4. What will happen to a ...
NH 2
NH 2

... methyl group of methionine may be transferred to an acceptor to become intermediates in metabolic pathway ...
DNA, RNA and Protein
DNA, RNA and Protein

... Made of Repeating Monomers Macromolecule Carbohydrates Lipids Proteins ...
Chapter 5 – Quiz #2-A Take Home Quiz
Chapter 5 – Quiz #2-A Take Home Quiz

File
File

... 1. Match the numbered stages with the correct lettered descriptions below 1. transcription ____ 2. replication ____ 3. translation ____ A) stage during which information coded in the base sequence of DNA is read to produce a strand of mRNA B) process during which the genetic code in RNA is used to m ...
Condensation Polymerisation
Condensation Polymerisation

... of glucose molecules. A condensation polymer is a polymer formed by the removal of atoms from adjacent monomer molecules to allow them to join together. Small molecules are produced as well as the polymer molecule and the process is known as condensation polymerisation. Formation of starch from gluc ...
Cellular Respiration
Cellular Respiration

... If oxygen is present, the pyruvate enters the mitochondrial matrix to complete the Krebs Cycle Pyruvate (3-C) is converted to Acetyl CoA (2-C) ...
Visualizing Macromolecules
Visualizing Macromolecules

... ____________________________ . Clearly the number of possible combinations is almost infinite when larger numbers of amino acids are combined to form a polypeptide. 3. What is PRIMARY STRUCTURE? ______________________________________________________________________________ __________________________ ...
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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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