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the kinship theory of genomic imprinting - Fischer Lab
... gene expression X. Then the kinship theory predicts that the evolutionarily stable strategy (ESS) at the locus will be either ‘symmetric’ or ‘asymmetric’ (21). A symmetric ESS occurs when maternally derived and paternally derived alleles favor the same total level of gene expression. At such an ESS, ...
... gene expression X. Then the kinship theory predicts that the evolutionarily stable strategy (ESS) at the locus will be either ‘symmetric’ or ‘asymmetric’ (21). A symmetric ESS occurs when maternally derived and paternally derived alleles favor the same total level of gene expression. At such an ESS, ...
Article Why There Are No Essential Genes on
... are differences between functions coded for by mobile genes and those in the “core” genome and that these differences can be seen between plasmids and chromosomes. In particular, it has been suggested that essential genes, such as those involved in the formation of structural proteins or in basic me ...
... are differences between functions coded for by mobile genes and those in the “core” genome and that these differences can be seen between plasmids and chromosomes. In particular, it has been suggested that essential genes, such as those involved in the formation of structural proteins or in basic me ...
Tabby pattern genetics – a whole new breed of cat
... domestic cats, Felis silvestris or Felis lybica, are both striped) and that (ii) ticked and blotched alleles were derived after cat domestication in different parts of the world. Placed in context of the present study, the Ti A and Tab alleles represent derivative variants at their respective loci, ...
... domestic cats, Felis silvestris or Felis lybica, are both striped) and that (ii) ticked and blotched alleles were derived after cat domestication in different parts of the world. Placed in context of the present study, the Ti A and Tab alleles represent derivative variants at their respective loci, ...
The Gene Ontology
... • Language used in biological research is not well controlled – This is hampered further by the wide variations in terminology that may be common usage at any given time, which inhibit effective searching by both computers and people. Adopted from http://www.geneontology.org/ ...
... • Language used in biological research is not well controlled – This is hampered further by the wide variations in terminology that may be common usage at any given time, which inhibit effective searching by both computers and people. Adopted from http://www.geneontology.org/ ...
SHY2/IAA3 regulates root development
... Seedlings for the gravitropic angle experiment were grown under different fluence rates of red light on vertically oriented plates as described previously (Reed et al., 1998). After 5 days growth, images were taken with a CCD camera, and angles between the growing direction of hypocotyls and the opp ...
... Seedlings for the gravitropic angle experiment were grown under different fluence rates of red light on vertically oriented plates as described previously (Reed et al., 1998). After 5 days growth, images were taken with a CCD camera, and angles between the growing direction of hypocotyls and the opp ...
Mutations of genes in synthesis of the
... Statistical analysis of segregation ratios of viviparous and non-viviparous plants demonstrated that the segregation of viviparous and non-viviparous plants is in line with the expected 2:1 ratio (Table S2). Furthermore, in T2 progeny (seeds in the ear) obtained from the viviparous plants, the mutan ...
... Statistical analysis of segregation ratios of viviparous and non-viviparous plants demonstrated that the segregation of viviparous and non-viviparous plants is in line with the expected 2:1 ratio (Table S2). Furthermore, in T2 progeny (seeds in the ear) obtained from the viviparous plants, the mutan ...
Diploidy and the selective advantage for sexual reproduction in
... organisms to survive in a co-evolutionary “genetic arms race” with quickly reproducing parasites. This theory derives its name from a character named the Red Queen in Lewis Carroll’s In the Looking Glass, who states, “It takes all the running you can do to stay in one place” (Hamilton et al. 1990). ...
... organisms to survive in a co-evolutionary “genetic arms race” with quickly reproducing parasites. This theory derives its name from a character named the Red Queen in Lewis Carroll’s In the Looking Glass, who states, “It takes all the running you can do to stay in one place” (Hamilton et al. 1990). ...
Quantitative genetics
... • Would we expect the allele to become more common where it is presently rare? • Use tools developed to model answers to such questions: Godfrey H. Hardy, a mathematician, and Wilhelm Weinberg, a physician, independently proposed a simple algebraic equation for analyzing alleles in populations. – Un ...
... • Would we expect the allele to become more common where it is presently rare? • Use tools developed to model answers to such questions: Godfrey H. Hardy, a mathematician, and Wilhelm Weinberg, a physician, independently proposed a simple algebraic equation for analyzing alleles in populations. – Un ...
A Century of Hardy–Weinberg Equilibrium
... consequently preferred what he called the sib method, whereby the segregation ratio in sibs of propositi is measured, weighting each sibship by the number of affected individuals. He also developed a method for the case where ascertainment was incomplete. In developing these methods, Weinberg was dr ...
... consequently preferred what he called the sib method, whereby the segregation ratio in sibs of propositi is measured, weighting each sibship by the number of affected individuals. He also developed a method for the case where ascertainment was incomplete. In developing these methods, Weinberg was dr ...
A Century of Hardy–Weinberg Equilibrium
... consequently preferred what he called the sib method, whereby the segregation ratio in sibs of propositi is measured, weighting each sibship by the number of affected individuals. He also developed a method for the case where ascertainment was incomplete. In developing these methods, Weinberg was dr ...
... consequently preferred what he called the sib method, whereby the segregation ratio in sibs of propositi is measured, weighting each sibship by the number of affected individuals. He also developed a method for the case where ascertainment was incomplete. In developing these methods, Weinberg was dr ...
South Asian people with diabetes referred for MODY testing have a
... SA people without mutations had higher BMIs than those with confirmed MODY mutations, suggesting that the low MODY detection rate in the SA group is due to a higher prevalence of young-onset, familial diabetes. This likely represents younger-onset type 2 diabetes. The best predictors of MODY in the ...
... SA people without mutations had higher BMIs than those with confirmed MODY mutations, suggesting that the low MODY detection rate in the SA group is due to a higher prevalence of young-onset, familial diabetes. This likely represents younger-onset type 2 diabetes. The best predictors of MODY in the ...
Handout - 6 - CM - Outline Genomic Model for HL7 V2
... This variable describes the relationship between the alleles found at the same locus on different chromosomes. It is not always discerned by the study See answer list The disorder with which this variant is associated. Allow same coding systems as for disease assessed , but this term may more often ...
... This variable describes the relationship between the alleles found at the same locus on different chromosomes. It is not always discerned by the study See answer list The disorder with which this variant is associated. Allow same coding systems as for disease assessed , but this term may more often ...
Tissue Polarity Genes of Drosophila Regulate the Subcellular
... genes are located very close to each other on the second chromosome, and are likely to represent a single complex locus (Gubb and Garcia-Bellido, 1982; Gubb, D., personal communication). In this paper, we will consider pk/sple as a single locus, and abbreviate the locus as pk. The pk I allele used i ...
... genes are located very close to each other on the second chromosome, and are likely to represent a single complex locus (Gubb and Garcia-Bellido, 1982; Gubb, D., personal communication). In this paper, we will consider pk/sple as a single locus, and abbreviate the locus as pk. The pk I allele used i ...
simple patterns of inheritance
... of such crosses showed characteristics of one or the other parent in successive generations. His intellectual foundation in physics and the natural sciences led him to consider that this regularity might be rooted in natural laws that could be expressed mathematically. To uncover these laws, he carr ...
... of such crosses showed characteristics of one or the other parent in successive generations. His intellectual foundation in physics and the natural sciences led him to consider that this regularity might be rooted in natural laws that could be expressed mathematically. To uncover these laws, he carr ...
Genetic Crosses
... Four alleles allows for 16 possible combinations of alleles. (16 box Punnett square) Four combinations of alleles can be determined by using the “foil” method of distribution. YyTt First pair of alleles = YT (dominant ) Outer pair of alleles = Yt (heterozygous) Inner pair of alleles = yT (hete ...
... Four alleles allows for 16 possible combinations of alleles. (16 box Punnett square) Four combinations of alleles can be determined by using the “foil” method of distribution. YyTt First pair of alleles = YT (dominant ) Outer pair of alleles = Yt (heterozygous) Inner pair of alleles = yT (hete ...
The molecular genetics of von Willebrand disease
... von Willebrand disease (VWD) is the most common inherited bleeding disease in humans, resulting in a clinical condition in which excessive mucocutaneous bleeding is the major manifestation. Significant progress has been made in the past decade in defining the molecular genetic basis of this conditio ...
... von Willebrand disease (VWD) is the most common inherited bleeding disease in humans, resulting in a clinical condition in which excessive mucocutaneous bleeding is the major manifestation. Significant progress has been made in the past decade in defining the molecular genetic basis of this conditio ...
Evolution of Immunoglobulin Kappa Chain Variable Region
... Only boostrap probability (BP) . 50% and confidence probability (CP) . 50% are shown above and below each interior branch, respectively. CP is usually higher than BP, but it is not shown for interior branches which are unimportant in our discussion. The BP and CP values that show significant statist ...
... Only boostrap probability (BP) . 50% and confidence probability (CP) . 50% are shown above and below each interior branch, respectively. CP is usually higher than BP, but it is not shown for interior branches which are unimportant in our discussion. The BP and CP values that show significant statist ...
Mixed modelling to characterize genotype-phenotype
... we examine combinations of four SNPs in three lipase genes as an example to test for higherorder interactions between genes of candidate gene pathways that may act synergistically to inuence obesity. Characterizing the association between multiple SNPs and disease outcomes will oer new insight int ...
... we examine combinations of four SNPs in three lipase genes as an example to test for higherorder interactions between genes of candidate gene pathways that may act synergistically to inuence obesity. Characterizing the association between multiple SNPs and disease outcomes will oer new insight int ...
Epistasis
![](https://commons.wikimedia.org/wiki/Special:FilePath/Epistatic_hair.png?width=300)
Epistasis is a phenomenon that consists of the effect of one gene being dependent on the presence of one or more 'modifier genes' (genetic background). Similarly, epistatic mutations have different effects in combination than individually. It was originally a concept from genetics but is now used in biochemistry, population genetics, computational biology and evolutionary biology. It arises due to interactions, either between genes, or within them leading to non-additive effects. Epistasis has a large influence on the shape of evolutionary landscapes which leads to profound consequences for evolution and evolvability of traits.