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Gene Duplication - Semantic Scholar
... duplication is the primary source of new genes in evolution, and duplicate genes form gene families that are abundantly found in almost all genomes. For these reasons, gene duplication has been a main focus of molecular evolutionary study for decades. Recent ye ...
... duplication is the primary source of new genes in evolution, and duplicate genes form gene families that are abundantly found in almost all genomes. For these reasons, gene duplication has been a main focus of molecular evolutionary study for decades. Recent ye ...
me-6 - Genetics
... flanking markers of parental combination represents conversion of the mutant site further from an end of the pairing region; the hybrid-DNA model, on the contrary, predicts that the more frequent class represents conversion of the site nearer an end of the pairing region. In tetrads, a similar relat ...
... flanking markers of parental combination represents conversion of the mutant site further from an end of the pairing region; the hybrid-DNA model, on the contrary, predicts that the more frequent class represents conversion of the site nearer an end of the pairing region. In tetrads, a similar relat ...
PcGs and Hox genes - Development
... that lack the function of these genes. To assay Hox gene silencing in such clones, we monitored the expression of three Hox genes Ubx, Abdominal-B (Abd-B) and caudal (cad) in the imaginal wing disc, where they are normally stably repressed using antisera against their protein products. For each PcG ...
... that lack the function of these genes. To assay Hox gene silencing in such clones, we monitored the expression of three Hox genes Ubx, Abdominal-B (Abd-B) and caudal (cad) in the imaginal wing disc, where they are normally stably repressed using antisera against their protein products. For each PcG ...
Mendel`s Pea Plants
... What’s the Chance of a Coin Landing on Heads? There is always a 50-50 chance that a coin will land on heads. Half the time it will land on heads and half the time it will land on tails. What is the chance of it landing on heads twice in a row? What about three times? These rules of probability, or t ...
... What’s the Chance of a Coin Landing on Heads? There is always a 50-50 chance that a coin will land on heads. Half the time it will land on heads and half the time it will land on tails. What is the chance of it landing on heads twice in a row? What about three times? These rules of probability, or t ...
Association between IGF1R / i16 / TaqI and IGF1 / SnaBI
... usefulness of this polymorphism may be limited by the low B allele frequency and its presence in only Bos indicus cattle. After a decade, as an indirect result of WGS libraries, more than 220 single nucleotide polymorphisms (SNPs) were identified in the Bos taurus IGF1R gene (http://www.ncbi.nlm.nih ...
... usefulness of this polymorphism may be limited by the low B allele frequency and its presence in only Bos indicus cattle. After a decade, as an indirect result of WGS libraries, more than 220 single nucleotide polymorphisms (SNPs) were identified in the Bos taurus IGF1R gene (http://www.ncbi.nlm.nih ...
Case 398 Submitting Author: Hutchison, Robert E, MD Institution
... often considered to be a primary abnormality ...
... often considered to be a primary abnormality ...
Characterization of the snowy cotyledon 1 mutant of Arabidopsis
... They were amplified by PCR and subsequently sequenced. In one of these genes (At1g62750) a point mutation with a G-to-A mutation was detected. This nucleotide exchange caused an amino acid change from glycine to arginine at position 132 (G132R). The gene At1g62750 encodes a predicted chloroplast-loca ...
... They were amplified by PCR and subsequently sequenced. In one of these genes (At1g62750) a point mutation with a G-to-A mutation was detected. This nucleotide exchange caused an amino acid change from glycine to arginine at position 132 (G132R). The gene At1g62750 encodes a predicted chloroplast-loca ...
Networks in leaf development
... expression patterns of these genes clearly indicate that they form an orthologous gene family. The mutant phenotype in each species is not immediately comparable, however, leading to disparate interpretations of the defect. In phan mutants, early leaves have patches of abaxial tissue associated with ...
... expression patterns of these genes clearly indicate that they form an orthologous gene family. The mutant phenotype in each species is not immediately comparable, however, leading to disparate interpretations of the defect. In phan mutants, early leaves have patches of abaxial tissue associated with ...
document
... a rare mutation on a gene called Cbfa1 that disrupts normal bone development. He had seven wives & now about a thousand of his descendants inherited a trait that reduces the clavicles (collarbones). Describe how this is an example of the founder effect. ...
... a rare mutation on a gene called Cbfa1 that disrupts normal bone development. He had seven wives & now about a thousand of his descendants inherited a trait that reduces the clavicles (collarbones). Describe how this is an example of the founder effect. ...
Cardiology Panel List
... R55 Syncope and collapse R94.31 Abnormal electrocardiogram (ECG or EKG) Z86.74 Personal history of sudden cardiac arrest Z82.41 Family history of sudden cardiac death Z84.81 Family history of carrier of genetic disease ...
... R55 Syncope and collapse R94.31 Abnormal electrocardiogram (ECG or EKG) Z86.74 Personal history of sudden cardiac arrest Z82.41 Family history of sudden cardiac death Z84.81 Family history of carrier of genetic disease ...
file
... the situation such that only one locus with two alleles, say A and a, determines the condition of both males and females (see table 1 for a list of symbols). Condition in turn determines viability, and in the case of males it can also have an influence on their sexual appearance. We introduce female ...
... the situation such that only one locus with two alleles, say A and a, determines the condition of both males and females (see table 1 for a list of symbols). Condition in turn determines viability, and in the case of males it can also have an influence on their sexual appearance. We introduce female ...
Biology 164 Laboratory Genetic Mutants of the Prodigiosin
... chemistry. Different alleles for specific genes are expressed by different organisms and can sometimes be interpreted from physical, identifiable characteristics. If mutations are incorporated into the genome of a cell or organism, these will often be apparent through the resulting phenotypic differ ...
... chemistry. Different alleles for specific genes are expressed by different organisms and can sometimes be interpreted from physical, identifiable characteristics. If mutations are incorporated into the genome of a cell or organism, these will often be apparent through the resulting phenotypic differ ...
population
... • We can assume the locus that causes phenylketonuria (PKU) is in Hardy-Weinberg equilibrium given that: – The PKU gene mutation rate is low – Mate selection is random with respect to whether or not an individual is a carrier for the ...
... • We can assume the locus that causes phenylketonuria (PKU) is in Hardy-Weinberg equilibrium given that: – The PKU gene mutation rate is low – Mate selection is random with respect to whether or not an individual is a carrier for the ...
The Advantages of Segregation and the Evolution of Sex
... Third, consider directional selection causing the spread of a favored allele, A, within a population. Although it is nonstandard, I continue to use the fitness regime described by (2) as this makes it easier to recognize parallels between the results with purifying and directional selection. The arg ...
... Third, consider directional selection causing the spread of a favored allele, A, within a population. Although it is nonstandard, I continue to use the fitness regime described by (2) as this makes it easier to recognize parallels between the results with purifying and directional selection. The arg ...
Heterosis, epistasis and linkage disequilibrium in
... participates with Acrueu encedon L. and other acraeids in no less than four distinct, sympatric Mullerian assemblages (Owen, 197 11, each with its attendant Batesian members. These are by no means local phenomena, for at least two of the Mullerian groupings are found throughout East Africa and Pierr ...
... participates with Acrueu encedon L. and other acraeids in no less than four distinct, sympatric Mullerian assemblages (Owen, 197 11, each with its attendant Batesian members. These are by no means local phenomena, for at least two of the Mullerian groupings are found throughout East Africa and Pierr ...
Leukaemia Section del(17p) in myeloïd malignancies Atlas of Genetics and Cytogenetics
... but also eosinophilic and basophilic lineages; such abnormalities can be observed both in the bone marrow and in the peripheral blood; however, in the latter instance, it may be difficult to demonstrate pseudoPelger Huët anomaly, due to frequent neutropenia; these nuclear changes mimick those found ...
... but also eosinophilic and basophilic lineages; such abnormalities can be observed both in the bone marrow and in the peripheral blood; however, in the latter instance, it may be difficult to demonstrate pseudoPelger Huët anomaly, due to frequent neutropenia; these nuclear changes mimick those found ...
Allele mining in the pepper gene pool provided new
... specificities are explained by the occurrence of small allelic series where distinct alleles are represented as a combination of distinct amino acid substitutions. The exact mechanism by which eIF4E mutations control resistance remains to be elucidated, but protein–protein interaction studies have s ...
... specificities are explained by the occurrence of small allelic series where distinct alleles are represented as a combination of distinct amino acid substitutions. The exact mechanism by which eIF4E mutations control resistance remains to be elucidated, but protein–protein interaction studies have s ...
Mutations affecting development of the zebrafish retina
... Drosophila eye, genes involved in the specification of the eye imaginal discs (Halder et al., 1995), progression of the morphogenetic furrow (Haberlein et al., 1993; Ma et al., 1993; Brown et al., 1995) and specification of photoreceptor cell fates (Tomlinson et al., 1988; Baker et al., 1990; review ...
... Drosophila eye, genes involved in the specification of the eye imaginal discs (Halder et al., 1995), progression of the morphogenetic furrow (Haberlein et al., 1993; Ma et al., 1993; Brown et al., 1995) and specification of photoreceptor cell fates (Tomlinson et al., 1988; Baker et al., 1990; review ...
Wheeler Quantitative Genetics
... The sum of all average allelic effect at each locus influencing the trait(s) of interest. (Alleles, not genotypes are passed on to the next generation) Breeding value is a concept associated with parents in a sexually breeding population. It can be measured. Historically, average allelic effects cou ...
... The sum of all average allelic effect at each locus influencing the trait(s) of interest. (Alleles, not genotypes are passed on to the next generation) Breeding value is a concept associated with parents in a sexually breeding population. It can be measured. Historically, average allelic effects cou ...
Letter Neighboring Genes Show
... 2004). Closely located genes show more similar gene expression patterns than randomly chosen gene pairs. The general phenomenon of coexpression of neighboring genes has been reported in several model eukaryotes such as Saccharomyces cerevisiae (Kruglyak and Tang 2000; Fukuoka et al. 2004; Lercher an ...
... 2004). Closely located genes show more similar gene expression patterns than randomly chosen gene pairs. The general phenomenon of coexpression of neighboring genes has been reported in several model eukaryotes such as Saccharomyces cerevisiae (Kruglyak and Tang 2000; Fukuoka et al. 2004; Lercher an ...
Gene interactions in the evolution of genomic imprinting
... reflect this pattern, we assign the same subscripts to those alleles that work best together. We focus on this form of epistasis because it does not contain any dominance effect, and therefore these models are not influenced by selection on dominance modification, discussed above. This model further ...
... reflect this pattern, we assign the same subscripts to those alleles that work best together. We focus on this form of epistasis because it does not contain any dominance effect, and therefore these models are not influenced by selection on dominance modification, discussed above. This model further ...
Epistasis
![](https://commons.wikimedia.org/wiki/Special:FilePath/Epistatic_hair.png?width=300)
Epistasis is a phenomenon that consists of the effect of one gene being dependent on the presence of one or more 'modifier genes' (genetic background). Similarly, epistatic mutations have different effects in combination than individually. It was originally a concept from genetics but is now used in biochemistry, population genetics, computational biology and evolutionary biology. It arises due to interactions, either between genes, or within them leading to non-additive effects. Epistasis has a large influence on the shape of evolutionary landscapes which leads to profound consequences for evolution and evolvability of traits.