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Journal of Plant Physiology
Journal of Plant Physiology

... was also observed following overexpression of tobacco Tsi1 (Shin et al., 2002), Arabidopsis TDR1 (Gutterson and Reuber, 2004), and hot pepper CaPF1 (Yi et al., 2004; Tang et al., 2005). Overexpression of various ERF genes, including Tsi1 and OPBP1 of tobacco (Park et al., 2001; Guo et al., 2004), Ca ...
Slides on chromosomal changes
Slides on chromosomal changes

... isolation between species. 2) A number of crop plants have undergone such changes and chromosome manipulation may be important in agriculture (breeding). 3) A number of such changes are responsible for human genetic diseases. 4) They may disrupt gene function directly if a break occurs in a gene. 5) ...
Phenotypic overlap in the contribution of individual genes to CNV
Phenotypic overlap in the contribution of individual genes to CNV

... A phenogram of a CNV represents the network of genes and related phenotypes that have been associated with the genes in a particular CNV interval. All phenotype matches above a threshold, calculated based on the phenotype IC of the closest match (Resnik, 1995), are used to form a phenogram. For exam ...
Identification of alternative spliced mRNA variants related to(1).
Identification of alternative spliced mRNA variants related to(1).

... and their tissue distribution in BASD A total of 4322 reference sequences were screened and 3490(81%) reference sequences were predicted as alternative spliced ,producing 26,812 splicing variants.  On average six splicing variants were observed for each reference sequences.  87% variants contained ...
A Yale geneticist and a Chinese lab are creating the Amazon.com of
A Yale geneticist and a Chinese lab are creating the Amazon.com of

... Research Center. The first buildTransposons are common in plants and insects, ing, with about 25,000 square feet and scientists have used a similar technology to create mutants in insect species. But before Xu, no of mouse space, went up in just six months, Xu says, one had been able to find a trans ...
here - Genetics
here - Genetics

... o r more base-pair positions, and since any of four different base-pairs may occupy any one position, the number of possible mutant alleles is very large. It is important that each mutant allele of a particular locus be given a unique designation; e.g., by the use of serial numbers as suffixes. Use ...
TimeClust: a clustering tool for gene expression time series
TimeClust: a clustering tool for gene expression time series

... containing about 42000 clones. Moreover, in [1] each clone has been associated to a specific phase of the cell cycle on the basis of the temporal location of the peak of expression. Two subsets of clones identified by Whitfiled et al. was selected and data are distributed as an example with TimeClus ...
McVean_CGAT_Mar2013
McVean_CGAT_Mar2013

... Mende in Sierra Leone (MSL) Esan in Nigeria (ESN) ...
Selecting differentially expressed genes for colon tumor classification
Selecting differentially expressed genes for colon tumor classification

... the SVM significantly outperformed all other investigated methods. Therefore the SVM technique can be regarded as a very promising supervised learning tool dealing with microarray gene expression data. Choosing a proper learning and classification method is a final and very important element in the ...
Fc RIIIB Gene Duplication: Evidence for Presence and Expression of
Fc RIIIB Gene Duplication: Evidence for Presence and Expression of

... digested with SfaNI, which recognizes a 58-GATGC-38 sequence present only in the SH-FcgRIIIB–derived fragment.10 Figure 3 shows the results of this digestion. Lane 1 shows SfaNI treatment of a fragment amplified from a plasmid containing SH-FcgRIIIb–encoding cDNA, resulting in a single band of 137 b ...
Candidate interactions EDITORIAL
Candidate interactions EDITORIAL

... Power issues and publication bias toward significant interactions explain why gene–environment interactions appear much more often in the discussion section of papers than with actual facts. However, evidence in this field is increasing [12] and recent papers in the European Respiratory Journal have ...
DNA methylation profile in human CD4+ T cells identifies
DNA methylation profile in human CD4+ T cells identifies

... center of methylation peaks and the transcription start sites of methylated genes that are expressed compared to non-expressed genes. The center of methylation peaks was on average 449bp further upstream from the transcription start site in expressed genes as compared to non-expressed genes (-1342±2 ...
Other Blood Groups
Other Blood Groups

... 25 antigens that define the Kell blood group.  The Kell protein is a polypeptide chain of 732 amino acids in length that becomes glycosylated at five different sites. It makes a single pass through the RBC membrane. ...
Secondary Science assessments
Secondary Science assessments

... Name: __________________________________________ Per: _____ Date: _________  ...
Duplication and Inherited Susceptibility of Chromosome 15q11
Duplication and Inherited Susceptibility of Chromosome 15q11

... often regarded as gifted at solving jigsaw puzzles. It is possible, therefore, that there is a biological and genetic basis for the commonalities between these disorders. This remains to be demonstrated, but it is an area of great interest to those groups that study the genetics and psychopathology ...
Antibiotic Resistance: How and So What?
Antibiotic Resistance: How and So What?

... • Bacteria become resistant through mutations or by getting genes from other bacteria. • We should only use antibiotics when we really need to. • Overuse in agriculture and at home encourages appearance of resistant bugs. ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... The specimens were cultured on MacConkey agar (Himedia-India) and incubated at 37℃ for 24 hours under aerobic conditions in order to differentiate the lactose fermented bacteriafrom the non-lactose fermented bacteria. Well isolated colonies were selected and cultured on Eosin methylene blue agar (Hi ...
B/B a/a - kcpe-kcse
B/B a/a - kcpe-kcse

... Sickle cell anemia may be the result of a genetic mutation that happened in malariaprone regions like Africa thousands of years ago. People with sickle cell trait may have been more likely to survive malaria epidemics and because they survived when others did not, this allowed the trait to be passe ...
Mitochondrial DNA Mutations and Disease
Mitochondrial DNA Mutations and Disease

... through the electron transport chain and finally given to oxygen, creating a protongradient, which drives ATP synthesis. Most patients with mitochondrial disorders have molecular defects affecting the mitochondrial OXPHOS system, consisting of ~ 87 protein subunits, forming five multi-protein comple ...
Lecture 7 - Pitt CPATH Project
Lecture 7 - Pitt CPATH Project

... • Assumption: there are recognizable signals in the DNA sequence that the cell uses; it should be possible to detect these algorithmically • Many programs designed to detect these signals • These programs do work to a certain extent, the information they provide is better than nothing; high error ra ...
14-2 Human Chromosomes
14-2 Human Chromosomes

... On The X & Y Chromosome X – Contains > 100 Genes Y – Contains Only A Few Genes Foothill High School Science Department ...
University of Groningen Methionine
University of Groningen Methionine

... were added into RNA-free screw-cap tubes containing 0.5 g glass beads, 50 ml 10 % SDS, 500 ml phenol/chloroform: isoamylalcohol, macaloid layer (150–175 ml, not exact as it is highly viscous). To break the cells the screw-cap tubes were placed in a bead beater and two 1 min pulses were applied with ...
Depth-stratified functional and taxonomic niche
Depth-stratified functional and taxonomic niche

... 2008), and commonly constitutes a large fraction of total psbA genes in marine microbial metagenomes (Sharon et al., 2007). Beyond elevating cyanophage fitness, these viral psbA gene copies alter the evolutionary trajectory of globally distributed cyanobacterial photosystems as the viral versions ev ...
Notes
Notes

... • The problem we have dealt with so far only have dealt with 2 alleles ­ the dominant allele and the recessive allele. The dominant allele controlled the trait. • Multiple Alleles ­ when more than 2 different alleles exist for a trait. Ex) the fruit fly Drosophilz ­ many different eye colors are pos ...
Genetic Engineering and Biotechnology
Genetic Engineering and Biotechnology

... “foreign” piece of DNA has single-stranded ends identical in base sequence to the sticky ends on the original DNA.  The “foreign” DNA has ends with this particular base sequence because it was cut from a larger molecule by the same restriction enzyme used to cut the original DNA. 4. The complementa ...
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Minimal genome

The concept of minimal genome assumes that genomes can be reduced to a bare minimum, given that they contain many non-essential genes of limited or situational importance to the organism. Therefore, if a collection of all the essential genes were put together, a minimum genome could be created artificially in a stable environment. By adding more genes, the creation of an organism of desired properties is possible. The concept of minimal genome arose from the observations that many genes do not appear to be necessary for survival. In order to create a new organism a scientist must determine the minimal set of genes required for metabolism and replication. This can be achieved by experimental and computational analysis of the biochemical pathways needed to carry out basic metabolism and reproduction. A good model for a minimal genome is Mycoplasma genitalium, the organism with the smallest known genome. Most genes that are used by this organism are usually considered essential for survival; based on this concept a minimal set of 256 genes has been proposed.
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