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Notes for a course in Behavioral Genetics and Evolution
Notes for a course in Behavioral Genetics and Evolution

... See the reading assignment for definitions of mean, variance, standard deviation, z-score, scatter plot, and correlation. Correlation is perhaps the most important statistical concept for the first half of this course, and we will need to focus on certain features of correlations that are not emphas ...
PopCycle Tutorial
PopCycle Tutorial

... An introduction to population genetics in the upper left corner of the window, with eggs and sperm floating and swimming around in it. The darker gametes carry allele A; the lighter ones carry allele a. The allele frequencies in the default gene pool are 0.5 for A and 0.5 for a. We want to simulate ...
GeneticsProtocol Lab student hand out
GeneticsProtocol Lab student hand out

... alleles of a human gene, and can therefore be inherited from one generation to the next. Human geneticists illustrate the inheritance of a gene within a family by using a pedigree chart. On such a chart, males are symbolized by a square (□) and females are symbolized by a circle (○). People who are ...
Review: To bud until death: The genetics of ageing in the yeast
Review: To bud until death: The genetics of ageing in the yeast

... death of the organism, has often been dismissed on evolutionary grounds. The primary argument is that there is no selection for genes which act during a period of life which most organisms in a natural population never reach because of predation or deleterious environmental conditions. In fact, *Add ...
Statistical analysis of DNA microarray data
Statistical analysis of DNA microarray data

... Which genes to use for normalization  Housekeeping genes  Genes involved in essential activities of cell maintenance and survival, but not in cell function and proliferation  These genes will be similarly expressed in all samples.  Difficult to identify – need to be confirmed  Affymetrix GeneC ...
Hox genes and the regulation of movement in Drosophila
Hox genes and the regulation of movement in Drosophila

... female cells to form circuitry that generates malespecific courtship behavior (Demir and Dickson, 2005). Here we provide evidence for a more generalized form of genetic control that assigns equivalent cells at different levels in the anterior–posterior axis to form the different networks that underli ...
Genetic determinants of sports participation and daily physical activity
Genetic determinants of sports participation and daily physical activity

... linkage) indicating signi®cant linkage between a marker locus and a locus causing the phenotype. The mode of inheritance has to be known to perform this type of model-based analysis on family data. The sib-pair linkage method, based on the principle of Haseman and Elston,8 is a non-parametric method ...
Section 14-1 - Cloudfront.net
Section 14-1 - Cloudfront.net

... • Turn in Extra Credit work from Friday • Quiz – Rescheduled to Monday( Section 14.1) • Homework: • Worksheet # 1 • Study for the Quiz ...
Data Availability and NASC tools
Data Availability and NASC tools

... • It shows experiments where genes chosen are highly variable, over all the experiments in the database. • Shows if genes are correlated in any way. • It also allows you to pick slides that are different from the general trend. • This tool plots a scatter plot of the two genes you select over all ex ...
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Document

... X-Linked Traits: Gene on X chromosome is carrying trait. • Recessive – Only males are affected – Passed from unaffected mothers to sons – Affected fathers will only transmit to heterozygous, unaffected daughters ...
4_Mendelian Genetics
4_Mendelian Genetics

... X-Linked Traits: Gene on X chromosome is carrying trait. • Recessive – Only males are affected – Passed from unaffected mothers to sons – Affected fathers will only transmit to heterozygous, unaffected daughters ...
Elucidating the Role of Gonadal Hormones in Sexually
Elucidating the Role of Gonadal Hormones in Sexually

... In the liver, metabolism of steroid hormones and drugs has been shown to be sexually differentiated, mainly due to gonadal hormones causing differences in GH. Studies have indicated that sex differences in hepatic steroid metabolism may support a pregnant state when the liver is exposed to high cont ...
New Gene for Bacterial Blight Resistance in Rice Located
New Gene for Bacterial Blight Resistance in Rice Located

... Pi-ta2 (2). These results suggest that there is at least one multiple gene family for disease resistance in the centromeric region of chromosome 12. Pi-ta encodes the NBS-LRR type protein (1). The present study also located two closely linked NBS sequences to the centromeric region of chromosome 12. ...
DCW11, Down-Regulated Gene 11 in CW-Type
DCW11, Down-Regulated Gene 11 in CW-Type

... identified in total 32 hapless mutants, which displayed distorted genotype segregation. Twenty-nine of them were deficient in steps later than pollen germination rather than pollen development. SETH1 and SETH2 are genes encoding glycosylphosphatidylinositol-anchoring proteins, and essential for main ...
Trachemys scripta elegans Red-Eared Turtle ( Fc)
Trachemys scripta elegans Red-Eared Turtle ( Fc)

... which the secretory tail is not encoded by a separate exon but rather by the sequence immediately downstream of the CH2 exon (21). Because Igs play important roles in the adaptive immune system of all jawed vertebrates (1, 2), they have been extensively studied in various groups of animals, includin ...
The 2R hypothesis and the human genome sequence
The 2R hypothesis and the human genome sequence

... Hox clusters in the vertebrate genome (Kappen et al., 1989), but only one in the invertebrate chordate amphioxus (Garcia-Fernandez and Holland, 1994). Phylogenetic analysis of the clusters showed that they duplicated early in vertebrate history. It seems certain that these clusters duplicated en blo ...
Molecular Genetics of Alcohol-Related Brain Damage
Molecular Genetics of Alcohol-Related Brain Damage

... role of these two genes in the pathophysiology of alcoholrelated thiamine deficiency but further studies need to be carried out. The WKS may be a very complex, multifactorial disorder where the interaction of multiple genes and environment play an important role in the pathogenesis (Fig. 2). However ...
Supplementary Methods 1. Generation and post
Supplementary Methods 1. Generation and post

... parameter values. We therefore find the optimal model by enumeration over these finite possibilities. We first loop over the n possible model breakpoints (including the possibility that the chromosome has only a single level), and for each potential breakpoint find the ‘basal’ level or levels that ...
coexpression database for animal species by
coexpression database for animal species by

... Funcoup (11) databases. A limited number of databases are now focusing on coexpression information as the main content, such as GeneFriends (12), GeneMANIA (13) and STARNET2 (14). Gene coexpression has a long range to search, even for weak functional associations. Thousands of genes are meaningfully ...
No Boundaries: Genomes, Organisms, and
No Boundaries: Genomes, Organisms, and

... from those of the environment, yet a central tenet of quantitative genetics is that gene expression is a consequence of the internal and external environments in which they are expressed. Lewontin (2000) emphasized this relationship by asserting there is no necessary demarcation between organisms an ...
Recurrent patterns of DNA copy number alterations in tumors reflect
Recurrent patterns of DNA copy number alterations in tumors reflect

... and more specifically that recurrent profiles at the level of PCA correlate with measured glycolytic phenotypes (FDGavidity in the tumor) as well as with increased proliferation. This primary PCA signature is also associated with p53 mutations, and hence may point towards a preponderance towards gen ...
chapter 15 the nervous system
chapter 15 the nervous system

... 24. A stroke leaves a person unable to speak, what part of the brain has probably been affected? 25. After a brain operation to remove a tumor, a person is no longer able to distinguish between sweet and sour tastes. What part of the brain has been affected? 26. Multiple sclerosis is a disease that ...
Autism Spectrum Disorder (ASD)
Autism Spectrum Disorder (ASD)

... Second, that no matter what life throws at you, you can keep your sense of humour and laugh your way through it. Every visit with her I came away happier than I arrived, and buoyed up. She had that special quality. Third, you can have a deep relationship without words, even without concepts, just by ...
What is a gene, post-ENCODE? History and updated definition
What is a gene, post-ENCODE? History and updated definition

... The concept of the “gene” has evolved and become more complex since it was first proposed (see timeline in Fig. 1, accompanying poster). There are various definitions of the term, although common initial descriptions include the ability to determine a particular characteristic of an organism and the ...
4. The cell’s supply of ADP, P , and NAD
4. The cell’s supply of ADP, P , and NAD

... NADH, both of these processes shut down when there is no available NAD+. 5. If the Krebs cycle does not require oxygen, why does cellular respiration stop after glycolysis when no oxygen is present? When no oxygen is present, oxidative phosphorylation cannot occur. As a result, the NADH produced in ...
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Biology and consumer behaviour

Consumer behaviour is the study of the motivations surrounding a purchase of a product or service. It has been linked to the field of psychology, sociology and economics in attempts to analyse when, why, where and how people purchase in the way that they do. However, little literature has considered the link between our consumption behaviour and the basics of our being, our biology. Segmentation by biological driven demographics such as sex and age are already popular and pervasive in marketing. As more knowledge and research is known, targeting based on a consumers biology is of growing interest and use to marketers.As human machines being made up of cells controlled by our brain to influence aspects of our behaviour, there must be some influence of biology on our consumer behaviour and how we purchase as well. The nature versus nurture debate is at the core of how much biology influences these buying decisions, because it argues the extent to which biological factors influence what we do, and how much is reflected through environmental factors. Neuromarketing is of interest to marketers in measuring the reaction of stimulus to marketing. Even though we know there is a reaction, the question of why we consume the way we do still lingers, but it is a step in the right direction. Biology helps to understand consumer behaviour as it influences consumption and aids in the measurement of it.Lawson and Wooliscroft (2004) drew the link between human nature and the marketing concept, not explicitly biology, where they considered the contrasting views of Hobbes and Rousseau on mankind. Hobbes believed man had a self-serving nature whereas Rousseau was more forgiving towards the nature of man, suggesting them to be noble and dignified. Hobbes saw the need for a governing intermediary to control this selfish nature which provided a basis for the exchange theory, and also links to Mcgregor’s Theory of X and Y, relevant to management literature. He also considered cooperation and competition, relevant to game theory as an explanation of man’s motives and can be used for understanding the exercising of power in marketing channels. Pinker outlines why the nature debate has been suppressed by the nurture debate in his book The Blank Slate.
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