TEV_v7_BY
... present in the C57BL/6J reference mouse genome are drawn from three distinct classes, namely short interspersed nuclear elements (SINEs), long interspersed nuclear elements (LINEs) and members of the endogenous retrovirus (ERV) superfamily. Despite their high prevalence, the relative contribution of ...
... present in the C57BL/6J reference mouse genome are drawn from three distinct classes, namely short interspersed nuclear elements (SINEs), long interspersed nuclear elements (LINEs) and members of the endogenous retrovirus (ERV) superfamily. Despite their high prevalence, the relative contribution of ...
Sager JJ, Bai Q, Burton EA
... novel and attractive system to study embryogenesis and organogenesis in vertebrates. The main reason is that both extensive genetic studies and detailed embryological analysis are possible using this small tropical fresh water teleost. However, in vitro analysis using cell culture or molecular genet ...
... novel and attractive system to study embryogenesis and organogenesis in vertebrates. The main reason is that both extensive genetic studies and detailed embryological analysis are possible using this small tropical fresh water teleost. However, in vitro analysis using cell culture or molecular genet ...
L18Selection
... We can define (natural) selection as differential reproduction of individuals within a population - an unavoidable consequence of variation in fitness, efficiency of reproduction. Fitness depends on viability, mating success (with sex), fecundity, and longevity. Usually, fitness of an individual ca ...
... We can define (natural) selection as differential reproduction of individuals within a population - an unavoidable consequence of variation in fitness, efficiency of reproduction. Fitness depends on viability, mating success (with sex), fecundity, and longevity. Usually, fitness of an individual ca ...
Evolutionary genetics of partial migration the threshold model of
... threshold characters. Threshold traits, such as migration propensity, maintain high levels of genetic variation, even under persistent and strong directional selection. This is due to the facts 1) that selection intensity decreases as selection proceeds, i.e. as the frequency of the selected type (m ...
... threshold characters. Threshold traits, such as migration propensity, maintain high levels of genetic variation, even under persistent and strong directional selection. This is due to the facts 1) that selection intensity decreases as selection proceeds, i.e. as the frequency of the selected type (m ...
publication
... Informatics database map and the Davis Human/Mouse homology map have been made by identifying human orthologs to mapped mouse genes (8). Detailed characterizations of disease regions are increasingly being done through mouse–human genomic comparisons aimed at identifying novel genes and regulatory e ...
... Informatics database map and the Davis Human/Mouse homology map have been made by identifying human orthologs to mapped mouse genes (8). Detailed characterizations of disease regions are increasingly being done through mouse–human genomic comparisons aimed at identifying novel genes and regulatory e ...
Chapter 11.4 Meosis and Sexual Reproduction
... When stained, they show similar banding patterns Because they have genes controlling the same traits at the same positions ...
... When stained, they show similar banding patterns Because they have genes controlling the same traits at the same positions ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... their own quality of care and compare with other centres to enable implementation of the local quality programe and improvement. The first step towards attainment of minimum standards of care has been encouraged on type and timing of record collection of statistical data for the measurement of outco ...
... their own quality of care and compare with other centres to enable implementation of the local quality programe and improvement. The first step towards attainment of minimum standards of care has been encouraged on type and timing of record collection of statistical data for the measurement of outco ...
PREIMPLANTATION GENETIC DIAGNOSIS
... until they are investigated after obstetric problems or the birth of an affected child. Couples in which one partner carries a dominant mutation will usually be aware of their risk, and might wish to avoid transmitting the disease to their offspring. PGD can be applied to three groups of genetic dis ...
... until they are investigated after obstetric problems or the birth of an affected child. Couples in which one partner carries a dominant mutation will usually be aware of their risk, and might wish to avoid transmitting the disease to their offspring. PGD can be applied to three groups of genetic dis ...
Calculation of allele frequencies of breeding
... frequencies refer to the percentage of certain alleles in that population. When the allele frequencies shift over time, microevolution occurred in that population. Five main reasons why allele frequencies change include natural selection, genetic drift (chance events), nonrandom mating, gene flow, a ...
... frequencies refer to the percentage of certain alleles in that population. When the allele frequencies shift over time, microevolution occurred in that population. Five main reasons why allele frequencies change include natural selection, genetic drift (chance events), nonrandom mating, gene flow, a ...
Phenotypic overlap in the contribution of individual genes to CNV
... gene/phenotype associations, approximately half of which were previously reported and half that were novel candidates. 431 associations were made solely on the basis of model organism phenotype data. Additionally, we observed a striking, statistically significant tendency for individual disease phen ...
... gene/phenotype associations, approximately half of which were previously reported and half that were novel candidates. 431 associations were made solely on the basis of model organism phenotype data. Additionally, we observed a striking, statistically significant tendency for individual disease phen ...
Parent–offspring conflict and the genetics of offspring solicitation
... 1974; Parker & Macnair 1979; Harper 1986; Davis et al. 1999). Once parental attentiveness to offspring signs of need has evolved, however, the coevolution between offspring demand and parental response in sexually reproducing organisms starts to be driven by the unequal genetic interests of parents ...
... 1974; Parker & Macnair 1979; Harper 1986; Davis et al. 1999). Once parental attentiveness to offspring signs of need has evolved, however, the coevolution between offspring demand and parental response in sexually reproducing organisms starts to be driven by the unequal genetic interests of parents ...
Imputation-Based Fine-Mapping Suggests that Most QTL in an
... data from multiple generations of divergently selected and relaxed lines, identified on-going ...
... data from multiple generations of divergently selected and relaxed lines, identified on-going ...
Directional selection can drive the evolution of
... results were sensitive to the starting populations, and no such effect was found (SI Appendix, Figs. S5 and S6). Because this burn-in period adds considerable computational time (a factor of 3), we opted to use the same starting population for all simulations. Random Genetic Drift. After the burn-in ...
... results were sensitive to the starting populations, and no such effect was found (SI Appendix, Figs. S5 and S6). Because this burn-in period adds considerable computational time (a factor of 3), we opted to use the same starting population for all simulations. Random Genetic Drift. After the burn-in ...
A Comparative Gene Map of the Horse (Equus caballus)
... fragments were designed to target specific genes from large paralogous gene families. Several of the isolated PCR products cloned were found to contain multiple fragments of highly homologous sequences, most likely amplified from different syntenic isoforms of paralogous genes (Table 1). For example ...
... fragments were designed to target specific genes from large paralogous gene families. Several of the isolated PCR products cloned were found to contain multiple fragments of highly homologous sequences, most likely amplified from different syntenic isoforms of paralogous genes (Table 1). For example ...
Genetics
... 1. EST-SSR discovery and validation in cowpea and genetic diversity 2. EST-SNP discovery and validation in cowpea and genetic diversity 3. SNP discovery from genotyping by sequencing in cowpea 4. Genetic diversity analysis for world-wide cowpea germplasm 5. Association analysis of low phosphorus eff ...
... 1. EST-SSR discovery and validation in cowpea and genetic diversity 2. EST-SNP discovery and validation in cowpea and genetic diversity 3. SNP discovery from genotyping by sequencing in cowpea 4. Genetic diversity analysis for world-wide cowpea germplasm 5. Association analysis of low phosphorus eff ...
- ResearchOnline@JCU
... of inheritance in at least a subset of serrated polyposis is likely. If not, however, serrated polyposis could be the result of several codominant alleles. We identified a severely affected kindred with serrated polyposis. The proband developed microsatellite instability (MSI)– CRC age 23 years arisi ...
... of inheritance in at least a subset of serrated polyposis is likely. If not, however, serrated polyposis could be the result of several codominant alleles. We identified a severely affected kindred with serrated polyposis. The proband developed microsatellite instability (MSI)– CRC age 23 years arisi ...
Modes of speciation in heterogeneous space
... reflects the primary selection given by the fitness functions f and K. On longer, evolutionary time scales, the population evolves through secondary selection, i.e., by adaptive mutations modifying its mating range wµ [32]. We study this process starting from a spatially uniform initial state with r ...
... reflects the primary selection given by the fitness functions f and K. On longer, evolutionary time scales, the population evolves through secondary selection, i.e., by adaptive mutations modifying its mating range wµ [32]. We study this process starting from a spatially uniform initial state with r ...
E-Halliburton chapter 8
... Between individuals sharing a (relatively recent) ancestor. One of the consequences is an increase in the frequency of homozygotes in the population. Recessive harmful genes will then manifest themselves, such as developmental and morphological effects, and reduced viability and fertility. This redu ...
... Between individuals sharing a (relatively recent) ancestor. One of the consequences is an increase in the frequency of homozygotes in the population. Recessive harmful genes will then manifest themselves, such as developmental and morphological effects, and reduced viability and fertility. This redu ...
Multiple Avirulence Loci and Allele-Specific Effector
... 1981) and barley powdery mildew (Brown and Simpson, 1994; Brown and Jessop, 1995; Brown et al., 1996; Caffier et al., 1996), which reported several examples where avirulence/virulence was genetically controlled by two loci in the fungus. To examine the inheritance of avirulence in the wheat Pm3 patho ...
... 1981) and barley powdery mildew (Brown and Simpson, 1994; Brown and Jessop, 1995; Brown et al., 1996; Caffier et al., 1996), which reported several examples where avirulence/virulence was genetically controlled by two loci in the fungus. To examine the inheritance of avirulence in the wheat Pm3 patho ...
Lab 7. Mendelian Genetics
... of unrelated species—it easy to lose sight of the basics of the process that makes it all possible. Depicting genetic make–up Genes control the characteristics of an organism. Alleles are alternate forms of a gene. For example, there is an allele for blond hair, another for black hair, etc. Only two ...
... of unrelated species—it easy to lose sight of the basics of the process that makes it all possible. Depicting genetic make–up Genes control the characteristics of an organism. Alleles are alternate forms of a gene. For example, there is an allele for blond hair, another for black hair, etc. Only two ...
- Philsci-Archive
... of those causes. Indeed, mutation, migration, multiple modes of selection, and random genetic drift are treated in more or less the same ways, i.e., by modifying and extending the basic mathematical statement of the Hardy-Weinberg Principle. Moreover, the basic tools roughly introduced here can be e ...
... of those causes. Indeed, mutation, migration, multiple modes of selection, and random genetic drift are treated in more or less the same ways, i.e., by modifying and extending the basic mathematical statement of the Hardy-Weinberg Principle. Moreover, the basic tools roughly introduced here can be e ...
Introductory genetics for veterinary students
... Is it reasonable to assume that the Q and q alleles will be alternatively “fixed” in the alternate F0 lines? Hence, that the QTL genotype of all F1 animals is the same? Especially when this is not the case for the SNP or microsatellite markers. This has lead to many erroneous conclusions of impr ...
... Is it reasonable to assume that the Q and q alleles will be alternatively “fixed” in the alternate F0 lines? Hence, that the QTL genotype of all F1 animals is the same? Especially when this is not the case for the SNP or microsatellite markers. This has lead to many erroneous conclusions of impr ...
Reprint
... the population are doing (i.e. it is frequency-dependent) and therefore these models are often allied more closely with phenotypic, continuoustrait game theory than with single locus genetics. As a result, the literature on kin selection is divided. It is not obvious how the findings of single locus ...
... the population are doing (i.e. it is frequency-dependent) and therefore these models are often allied more closely with phenotypic, continuoustrait game theory than with single locus genetics. As a result, the literature on kin selection is divided. It is not obvious how the findings of single locus ...
Woolfe, 2005
... CNEs found in clusters, in front of transdev genes CNEs act at large distances from coding sequence The relative order and positions of CNEs are conserved No vertebrate CNEs were found in invertebrates, even though the genes had clear homologs Many of these results are paralleled by a similar paper ...
... CNEs found in clusters, in front of transdev genes CNEs act at large distances from coding sequence The relative order and positions of CNEs are conserved No vertebrate CNEs were found in invertebrates, even though the genes had clear homologs Many of these results are paralleled by a similar paper ...
Human genetic variation
Human genetic variation is the genetic differences both within and among populations. There may be multiple variants of any given gene in the human population (genes), leading to polymorphism. Many genes are not polymorphic, meaning that only a single allele is present in the population: the gene is then said to be fixed. On average, in terms of DNA sequence all humans are 99.9% similar to any other humans.No two humans are genetically identical. Even monozygotic twins, who develop from one zygote, have infrequent genetic differences due to mutations occurring during development and gene copy-number variation. Differences between individuals, even closely related individuals, are the key to techniques such as genetic fingerprinting. Alleles occur at different frequencies in different human populations, with populations that are more geographically and ancestrally remote tending to differ more.Causes of differences between individuals include the exchange of genes during meiosis and various mutational events. There are at least two reasons why genetic variation exists between populations. Natural selection may confer an adaptive advantage to individuals in a specific environment if an allele provides a competitive advantage. Alleles under selection are likely to occur only in those geographic regions where they confer an advantage. The second main cause of genetic variation is due to the high degree of neutrality of most mutations. Most mutations do not appear to have any selective effect one way or the other on the organism. The main cause is genetic drift, this is the effect of random changes in the gene pool. In humans, founder effect and past small population size (increasing the likelihood of genetic drift) may have had an important influence in neutral differences between populations. The theory that humans recently migrated out of Africa supports this.The study of human genetic variation has both evolutionary significance and medical applications. It can help scientists understand ancient human population migrations as well as how different human groups are biologically related to one another. For medicine, study of human genetic variation may be important because some disease-causing alleles occur more often in people from specific geographic regions. New findings show that each human has on average 60 new mutations compared to their parents.Apart from mutations, many genes that may have aided humans in ancient times plague humans today. For example, it is suspected that genes that allow humans to more efficiently process food are those that make people susceptible to obesity and diabetes today.