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Hox, ParaHox, ProtoHox: facts and guesses
Hox, ParaHox, ProtoHox: facts and guesses

... Intermediate hypotheses can also be advanced, for example, a ProtoHox cluster with three genes (Anterior, Group3 and Posterior). In this case, Cnidarians would have lost PG3 and Xlox, and the increase in complexity at the origin of Bilaterians would have been linked only to the origin of a Central H ...
Multivariate Analysis of Genotype–Phenotype Association
Multivariate Analysis of Genotype–Phenotype Association

... large numbers of measurements, which may not bear biological meaning one by one. For such multivariate phenotypes, studying the pairwise associations between all measurements and all alleles is highly inefficient and prevents insight into the genetic pattern underlying the observed phenotypes. We pre ...
Evidence for Mitotic Crossing-over During the
Evidence for Mitotic Crossing-over During the

... The life-cycle of the cellular slime mould Dictyostelium discoideum has features which have made this organism particularly attractive for studies of cell differentiation (for reviews see Bonner, 1967; Garrod & Ashworth, 1973). The application of genetic methods of analysis to this organism has, how ...
Entering the second century of maize quantitative genetics
Entering the second century of maize quantitative genetics

... Heredity (2014) 112, 30–38; doi:10.1038/hdy.2013.6; published online 6 March 2013 Keywords: maize; nested association mapping; quantitative traits; genome-wide association; heterosis ...
Frequently Asked Questions (FAQs) What is this application related
Frequently Asked Questions (FAQs) What is this application related

... breeding or by genetic engineering using transgenes. A number of CMS systems have been tested in mustard. However, CMS/ restorer systems have been found to be inadequate for large scale hybrid seed production with high purity. CMS systems are either unstable or their restoration to fertility is inad ...
understanding heredity
understanding heredity

... At the outset, let us have a clear notion of one very important point. When heredity is mentioned, the nurseryman will think of his varieties of Rowers, the farmer will think of his seed and crops, the physician will think of his patients with "hereditary" or "constitutional" diseases. The layman, i ...
SNPs for individual identification
SNPs for individual identification

... studies included several small, isolated groups. Therefore, we have re-evaluated our data, as well as other data, after excluding the most isolated populations from consideration, reducing the screening panel from 40 to 31 populations, those most likely to be forensically relevant. A much larger pan ...
INVESTIGATING THE IMPORTANCE OF ANATOMICAL
INVESTIGATING THE IMPORTANCE OF ANATOMICAL

... For both SBP and SAP , similarity may be measured using either SimIC or SimJ . 2.2. Construction of ontologies We constructed three ontologies for computing semantic similarity: one without homology axioms (R), one with valid homology axioms (H ) and one with a random set of homology axioms (H 0 ). ...
G enetics - Lantern Publishing
G enetics - Lantern Publishing

... multiple alleles; lethal alleles. ...
Biomart/ GENOME ALIGNMENT III
Biomart/ GENOME ALIGNMENT III

... evolutionary history of species and in identifying functional regions in genomes. The possibilities for identifying regions under selection are enhanced with the addition of more sequences and this observation has led to numerous ‘focused sequencing’ projects which seek to obtain sequence for a smal ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... Recurrent abortion among Egyptian women was strongly associated with the mutations related to VEGF gene polymorphism. Characteristically, these cases showed high frequencies of VEGF C2578A, G1154A, and C634G mutation. Interestingly, VEGF C2578A, G1154A, and C634G mutation frequencies were relatively ...
Redalyc.Molecular Epidemiology and Evolution of Avian Infectious
Redalyc.Molecular Epidemiology and Evolution of Avian Infectious

... strains that replicate in many non-respiratory epithelial cells, where they may cause pathologies (e.g. kidney, genital tract), while others replicate on enteric surfaces and result in faecal excretion of the virus (Cavanagh, 2007), despite not normally producing clinical disease Collectively, the p ...
Genetic Homologies between Flagellar Antigens of
Genetic Homologies between Flagellar Antigens of

... Two different Salmonella abony Hfr donors were crossed to Escherichia coli strain EH 23 and, as a control, to S . abony strain SH 583, which are arg-mutants of the F- recipient strains used in the previous crosses. In both cases the mutant arg loci lie between his and str. Either his+, arg', or both ...
Genomics Reveal Ancient Forms of Stanniocalcin in Amphioxus and
Genomics Reveal Ancient Forms of Stanniocalcin in Amphioxus and

... Synopsis Stanniocalcin (STC) is present throughout vertebrates, including humans, but a structure for STC has not been identified in animals that evolved before bony fish. The origin of this pleiotropic hormone known to regulate calcium is not clear. In the present study, we have cloned three stanni ...
Mining Multi-Faceted Overviews of Arbitrary Topics in a Text Collection
Mining Multi-Faceted Overviews of Arbitrary Topics in a Text Collection

... • Adopting the six facets, our system started from the facet keywords and estimated facet models based on the entire collection. • Different methods are evaluated based on their final generated gene summaries. • The experiment was done on 19 randomly selected fruit fly genes. • We retrieved 463 sent ...
Comparative Genomics
Comparative Genomics

... We can find important, functional regions of the sequence (codons, promoters, regulatory regions) It can help us locate genes in other species that are missing or not welldefined (also through comparison and alignments). Quality control! ...
From the Department of Zoology, University of
From the Department of Zoology, University of

... component of chromosomes in both animal and plant cells. ...
Bioinformatics
Bioinformatics

... Venter, J. C. (1995). "Wholegenome random sequencing and assembly of Haemophilus influenzae rd." Genome sequence now Science 269: 496-512. accumulate so quickly that, (Picture adapted from TIGR website, in less than a week, a single http://www.tigr.org) laboratory can produce • Integrative Data more ...
the hemophilia gene, click here
the hemophilia gene, click here

... change or a mutation in a gene. The mutation causes the gene to not work properly. Like other genetic health problems, hemophilia can be passed from generation to generation. In about 3 out of 10 cases, however, a boy with hemophilia (or a girl who is a carrier of hemophilia) is born to a family tha ...
Horizontal transfer generates genetic variation in an asexual
Horizontal transfer generates genetic variation in an asexual

... coverage for the 612 type 2 SNPs in LS regions, 25 was the average depth for the 261 type 2 SNPs in the core genome, and 28 was the average depth for the 3031 type 1 SNPs in the whole genome. In sum, the type 2 SNPs in the core genome were dispersed with low depths of coverage in sequence contexts ...
The genetic basis of inherited anomalies of the teeth: Part 1: Clinical
The genetic basis of inherited anomalies of the teeth: Part 1: Clinical

... Clinical Genetics Unit, Department of Medical Genetics, and INSERM U676, AP-HP, Hôpital Robert Debré, Paris, France ...
Opsin genes, cone photopigments, color vision, and color blindness
Opsin genes, cone photopigments, color vision, and color blindness

... that the relative cone sensitivities depend on the relative numbers of the different cone types; namely, that 7% of all cones contain the S-cone pigment and that, of the remaining 93%, those containing the L-cone pigment are 1.5 times more frequent than those containing the M-cone pigment (see Chapt ...
Discovering the Distribution of Palindromic Sequences in the
Discovering the Distribution of Palindromic Sequences in the

... The appropriate .fasta files from GenBank were downloaded: Homo sapiens Chromosome 18, GRCh37.p5 Primary Assembly (region: 48,556,583 to 48,611,412) and Homo sapiens SMAD family member 4 (SMAD4)12 ( accession number NM_005359). The large deletion mutations on the SMAD4 database were converted into a ...
Telomere maintenance without telomerase
Telomere maintenance without telomerase

... Although the majority of yeast cells die in the absence of telomerase, Lundblad and Blackburn (1993) observed that a small subpopulation could escape the lethal consequences of a telomerase defect. The rare survivors recovered from an est1-D strain not only regained the ability to grow but also disp ...
Mutation - FSU Biology
Mutation - FSU Biology

... swamping out small differences in fitness. However, when N is large, even tiny differences in fitness reliably discriminate higher and lower fitness variants. Mutation-accumulation experiments are therefore designed to maximize the impact of drift, either by making N as small as possible, or by equa ...
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History of genetic engineering

Genetic modification caused by human activity has been occurring since around 12,000 BC, when humans first began to domesticate organisms. Genetic engineering as the direct transfer of DNA from one organism to another was first accomplished by Herbert Boyer and Stanley Cohen in 1973. Advances have allowed scientists to manipulate and add genes to a variety of different organism and induce a range of different effects. Since 1976 the technology has been commercialised, with companies producing and selling genetically modified food and medicine.
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