Statistical methods for detecting signals of natural selection
... of randomly drifting quantitative traits, resulting in a probability distribution over the evolutionary process. I use this distribution to construct statistical tests that can be used to detect signals of natural selection in quantitative traits. The method of this thesis is derived from the first ...
... of randomly drifting quantitative traits, resulting in a probability distribution over the evolutionary process. I use this distribution to construct statistical tests that can be used to detect signals of natural selection in quantitative traits. The method of this thesis is derived from the first ...
The Birth- and- Death Evolution of Multigene Families Revisited
... functions, whereas others deteriorate into pseudogenes or even get deleted from the genome? What ultimately lies at the heart of this question is the desire to understand how multigene families originate and diversify. The birth-and-death model of multigene family evolution provides a framework to a ...
... functions, whereas others deteriorate into pseudogenes or even get deleted from the genome? What ultimately lies at the heart of this question is the desire to understand how multigene families originate and diversify. The birth-and-death model of multigene family evolution provides a framework to a ...
Temporal Transcriptome Changes Induced by
... representing the early cytolytic, latent and late cytolytic stages, respectively. We observed similar gene expression profiles at the three time points in line 63 and RCS-M chickens that are both different from line 72. Pathway analysis using Ingenuity Pathway Analysis (IPA) showed that MDV can broa ...
... representing the early cytolytic, latent and late cytolytic stages, respectively. We observed similar gene expression profiles at the three time points in line 63 and RCS-M chickens that are both different from line 72. Pathway analysis using Ingenuity Pathway Analysis (IPA) showed that MDV can broa ...
Mining Phenotypes and Informative Genes from Gene Expression
... inconsistent signals for the samples in a phenotype, and thus cannot be used to distinguish phenotypes. They are called non-informative genes. If phenotype information is known, the major task is to select the informative genes that manifest the phenotypes of samples. This can be achieved by superv ...
... inconsistent signals for the samples in a phenotype, and thus cannot be used to distinguish phenotypes. They are called non-informative genes. If phenotype information is known, the major task is to select the informative genes that manifest the phenotypes of samples. This can be achieved by superv ...
F 1
... doctor for help. The doctor suspects that the condition might have a genetic basis. She recommends that the child be taken to a specialty clinic where physicians and staff members are trained to diagnose genetic diseases and counsel parents. Ultimately, the child is diagnosed with a rare recessively ...
... doctor for help. The doctor suspects that the condition might have a genetic basis. She recommends that the child be taken to a specialty clinic where physicians and staff members are trained to diagnose genetic diseases and counsel parents. Ultimately, the child is diagnosed with a rare recessively ...
Chapter 1 A Perspective on Human Genetics
... been found on some chromosomes • At present no genes have been discovered • Human Genome Project, along with other methods of study, may lead to identification of genes involved in behavior ...
... been found on some chromosomes • At present no genes have been discovered • Human Genome Project, along with other methods of study, may lead to identification of genes involved in behavior ...
A rough guide to Drosophila mating schemes (light version 2.1) 1
... used that carry gene mutations, chromosomal aberrations or transgenic constructs. These different fly variants are the bread-and-butter of fly research, providing the tools by which genes are manipulated or visualised in action in order to investigate their function. The art of Drosophila genetics i ...
... used that carry gene mutations, chromosomal aberrations or transgenic constructs. These different fly variants are the bread-and-butter of fly research, providing the tools by which genes are manipulated or visualised in action in order to investigate their function. The art of Drosophila genetics i ...
Notes - people.vcu.edu
... Variable vs fixed? Overlapping vs nonoverlapping? Triplet vs who-knows-what? In one remarkable experiment executed by Francis Crick, Leslie Barnet, Sydney Brenner, and RJ WattsTobin, these questions were largely resolved. This is a confusing experiment but a very important one. If you can grasp what ...
... Variable vs fixed? Overlapping vs nonoverlapping? Triplet vs who-knows-what? In one remarkable experiment executed by Francis Crick, Leslie Barnet, Sydney Brenner, and RJ WattsTobin, these questions were largely resolved. This is a confusing experiment but a very important one. If you can grasp what ...
Gold nanoparticle-mediated gene delivery induces immunity genes
... the variance, respectively. Along the first principal component, the samples treated with gold nanoparticle–oligonucleotide complexes were widely separated from the other samples, that is, most of the changes in PBMC gene expression occurred between these two sample groups. The fourth principal comp ...
... the variance, respectively. Along the first principal component, the samples treated with gold nanoparticle–oligonucleotide complexes were widely separated from the other samples, that is, most of the changes in PBMC gene expression occurred between these two sample groups. The fourth principal comp ...
16-2 Evolution as Genetic Change
... For example, a lizard population is normally brown, but has mutations that produce red and black forms. Red lizards are more visible to predators, so they will be less likely to survive and reproduce. Therefore, the allele for red color will become rare. ...
... For example, a lizard population is normally brown, but has mutations that produce red and black forms. Red lizards are more visible to predators, so they will be less likely to survive and reproduce. Therefore, the allele for red color will become rare. ...
Trawling DNA Databases for Partial Matches: What is the FBI Afraid
... DNA evidence is often presented as the "gold standard"for forensic science. But this was not always the case. For years, eminent scientists complained that the estimates of the tiny frequencies of DNA types were unfounded. It took scores of research papers, dozens of judicial opinions, and two commi ...
... DNA evidence is often presented as the "gold standard"for forensic science. But this was not always the case. For years, eminent scientists complained that the estimates of the tiny frequencies of DNA types were unfounded. It took scores of research papers, dozens of judicial opinions, and two commi ...
1 Gene trees and species trees The lines of organismal descent that
... Everything I have described so far applies equally to asexual and sexual population. In both cases each nucleotide position has an underlying tree involving coalescence as one looks backwards through time (and lineage sorting as one looks forward). The fundamental difference between an asexual and a ...
... Everything I have described so far applies equally to asexual and sexual population. In both cases each nucleotide position has an underlying tree involving coalescence as one looks backwards through time (and lineage sorting as one looks forward). The fundamental difference between an asexual and a ...
The genomic substrate for adaptive radiation in African cichlid fish
... from the O. niloticus Ensembl gene predictions. All annotation pipelines used assembled RNAseq data generated from several tissues from each of the sequenced species (See RNAsequencing – Sample source). All annotations were projected onto the species’ genome alignments and only genes with conserved ...
... from the O. niloticus Ensembl gene predictions. All annotation pipelines used assembled RNAseq data generated from several tissues from each of the sequenced species (See RNAsequencing – Sample source). All annotations were projected onto the species’ genome alignments and only genes with conserved ...
Natural selection mapping of the warfarin
... Score statistics (U tests) were used to specifically assess heterozygote deficiency and excess, and also by using the Markov Chain method at default settings. Probabilities associated with coefficients of linkage disequilibrium for all locus pairs and each population were estimated by using Fisher’s ...
... Score statistics (U tests) were used to specifically assess heterozygote deficiency and excess, and also by using the Markov Chain method at default settings. Probabilities associated with coefficients of linkage disequilibrium for all locus pairs and each population were estimated by using Fisher’s ...
Impact of Tandem Repeats on the Scaling of Nucleotide Sequences
... ABSTRACT Techniques such as detrended fluctuation analysis (DFA) and its extensions have been widely used to determine the nature of scaling in nucleotide sequences. In this brief communication we show that tandem repeats which are ubiquitous in nucleotide sequences can prevent reliable estimation o ...
... ABSTRACT Techniques such as detrended fluctuation analysis (DFA) and its extensions have been widely used to determine the nature of scaling in nucleotide sequences. In this brief communication we show that tandem repeats which are ubiquitous in nucleotide sequences can prevent reliable estimation o ...
Replication origin plasticity, Taylor-made: inhibition vs
... Abstract Among his many contributions to the field of chromosome structure and dynamics, J. Herbert Taylor showed that eukaryotic cells have many more potential replication origins than they use, which they can recruit when replication forks are slowed to complete S-phase in a timely fashion. Thirty ...
... Abstract Among his many contributions to the field of chromosome structure and dynamics, J. Herbert Taylor showed that eukaryotic cells have many more potential replication origins than they use, which they can recruit when replication forks are slowed to complete S-phase in a timely fashion. Thirty ...
Directions for Use Taq DNA Polymerase, 500U
... What is the source of AMRESCO’s UNG? The recombinant cod UNG is produced in an ung negative E. coli strain and is designed to replace the native UNG enzyme originating in Atlantic cod (Gadus morhua). What is the stability of recombinant cod UNG? UNG can tolerate multiple freeze-thaw cycles. It may a ...
... What is the source of AMRESCO’s UNG? The recombinant cod UNG is produced in an ung negative E. coli strain and is designed to replace the native UNG enzyme originating in Atlantic cod (Gadus morhua). What is the stability of recombinant cod UNG? UNG can tolerate multiple freeze-thaw cycles. It may a ...
From Gene to Carcinogen: A Rapidly Evolving Field in
... that one can probably distinguish between mutations caused by direct-acting carcinogens and tumors caused by "spontaneous" mutations by noting the frequency of one particular type of mutation, that arising from CpG dinucleotides, in the tumors. This distinction is clearly of the utmost importance si ...
... that one can probably distinguish between mutations caused by direct-acting carcinogens and tumors caused by "spontaneous" mutations by noting the frequency of one particular type of mutation, that arising from CpG dinucleotides, in the tumors. This distinction is clearly of the utmost importance si ...
Document
... present in the gametes. • In a diploid, the pair of factors segregate during gamete formation, and progeny inherit one factor of each pair of factors (one allele) from the mother and one from the father. • Each pair of factors assorts independently, such that new combinations are possible in progeny ...
... present in the gametes. • In a diploid, the pair of factors segregate during gamete formation, and progeny inherit one factor of each pair of factors (one allele) from the mother and one from the father. • Each pair of factors assorts independently, such that new combinations are possible in progeny ...
here
... A number of experimental reports showed that genes from distantly related Tetrapoda organisms were correctly expressed and post-transcriptionally modified in transgenic animals (Capetanaki Y et al.: Proc Natl Acad Sci USA 1989, Jacobs GH et al.: Science 2007) The genes encoding well-known RNA bindin ...
... A number of experimental reports showed that genes from distantly related Tetrapoda organisms were correctly expressed and post-transcriptionally modified in transgenic animals (Capetanaki Y et al.: Proc Natl Acad Sci USA 1989, Jacobs GH et al.: Science 2007) The genes encoding well-known RNA bindin ...
