letters - Lewis-Sigler Institute | for Integrative Genomics
... trait loci (QTLs) are thought to contribute to the genetics of many traits, and can markedly affect the power of genetic studies to detect QTLs1. Interacting loci have been identified in many organisms1–5. However, the prevalence of interactions6–8, and the nucleotide changes underlying them9,10, ar ...
... trait loci (QTLs) are thought to contribute to the genetics of many traits, and can markedly affect the power of genetic studies to detect QTLs1. Interacting loci have been identified in many organisms1–5. However, the prevalence of interactions6–8, and the nucleotide changes underlying them9,10, ar ...
Comparative Methods for the Analysis of Gene
... likely to contain some signal that is caused by crosshybridization, as RNA from one gene will likely hybridize to similar motifs in multiple different genes on a microarray. Cross-hybridization could affect our methods by artifactually increasing the estimated similarity of geneexpression patterns f ...
... likely to contain some signal that is caused by crosshybridization, as RNA from one gene will likely hybridize to similar motifs in multiple different genes on a microarray. Cross-hybridization could affect our methods by artifactually increasing the estimated similarity of geneexpression patterns f ...
A rapid and specific PCR–ELISA for detecting Salmonella typhi
... more convenient for rapid and reliable detection and quantification of pathogen-specific gene sequences (6,17,18). Thus, in vitro amplification of DNA by PCR has now become a potentially powerful alternative in microbiological diagnostics due to its rapidity and accuracy. A digoxigenin (DIG)-ELISA k ...
... more convenient for rapid and reliable detection and quantification of pathogen-specific gene sequences (6,17,18). Thus, in vitro amplification of DNA by PCR has now become a potentially powerful alternative in microbiological diagnostics due to its rapidity and accuracy. A digoxigenin (DIG)-ELISA k ...
Detection of the Most Common Genetic Causes of
... azoospermia and severe oligozoospermia (Foresta et al., 2000; Ma et al., 2000). In 1976, Tiepolo and Zuffardi provided the first evidence that the long arm of the Y chromosome is required for fertility in men, when they karyotyped 1170 men and found that six azoospermic men were missing most of the ...
... azoospermia and severe oligozoospermia (Foresta et al., 2000; Ma et al., 2000). In 1976, Tiepolo and Zuffardi provided the first evidence that the long arm of the Y chromosome is required for fertility in men, when they karyotyped 1170 men and found that six azoospermic men were missing most of the ...
Molecular ecology and selection in the drought-
... mechanistic complex trait. In terms of genetics, the multiple individual traits that make up drought tolerance are usually inherited quantitatively with very few major genes for drought tolerance mechanisms known, although Blair et al. [7] did find some quantitative trait loci for drought tolerance. ...
... mechanistic complex trait. In terms of genetics, the multiple individual traits that make up drought tolerance are usually inherited quantitatively with very few major genes for drought tolerance mechanisms known, although Blair et al. [7] did find some quantitative trait loci for drought tolerance. ...
Pro-Apoptotic Role of the Human YPEL5 Gene Identified by
... human YPEL3, which was described as a small unstable apoptotic protein in murine myeloid cells [4], has been reported to be involved in growth suppression, causing cellular senescence in human cell lines, and its expression is regulated by the tumor suppressor protein p53, with lower expression in s ...
... human YPEL3, which was described as a small unstable apoptotic protein in murine myeloid cells [4], has been reported to be involved in growth suppression, causing cellular senescence in human cell lines, and its expression is regulated by the tumor suppressor protein p53, with lower expression in s ...
X-chromosome inactivation: molecular mechanism and genetic
... heterozygous populations of cells. In case of X-linked mutations that are detrimental and even lethal, sons may not be affected of the mutant gene they express. Also growth competition between the mosaic populations can result in elimination of cells that express the mutant allele. ...
... heterozygous populations of cells. In case of X-linked mutations that are detrimental and even lethal, sons may not be affected of the mutant gene they express. Also growth competition between the mosaic populations can result in elimination of cells that express the mutant allele. ...
Fulltext PDF - Indian Academy of Sciences
... methylation pattern acquired in response to abiotic or biotic stress is often inherited over one to several subsequent generations. Cytosine methylation marks affect physiological functions of plants via their effect(s) on gene expression levels. They also repress transposable elements that are abun ...
... methylation pattern acquired in response to abiotic or biotic stress is often inherited over one to several subsequent generations. Cytosine methylation marks affect physiological functions of plants via their effect(s) on gene expression levels. They also repress transposable elements that are abun ...
PP - FTHS Wiki
... Use root letter “I” for dominant alleles of equal strength and “i” for recessive ...
... Use root letter “I” for dominant alleles of equal strength and “i” for recessive ...
Mendel`s Experiments
... Mendel’s Results • All of Mendel’s F1 (first generation) plants expressed the same trait for a given character. The contrasting trait seemed to have disappeared. • The contrasting trait reappeared, however, in some of the F2 plants when the F1 plants were allowed to self-pollinate. But, most import ...
... Mendel’s Results • All of Mendel’s F1 (first generation) plants expressed the same trait for a given character. The contrasting trait seemed to have disappeared. • The contrasting trait reappeared, however, in some of the F2 plants when the F1 plants were allowed to self-pollinate. But, most import ...
Taking Heredity to Heart and Head: Cardiovascular Disease Genetics
... • Powerful tool that can identify individuals at increased disease risk who may benefit from targeted personal health promotion efforts and prevention therapies • Reflects shared genetic susceptibilities, shared environment, and common behaviors • Both easily and inexpensively obtained on a routine ...
... • Powerful tool that can identify individuals at increased disease risk who may benefit from targeted personal health promotion efforts and prevention therapies • Reflects shared genetic susceptibilities, shared environment, and common behaviors • Both easily and inexpensively obtained on a routine ...
Dogs for trait mapping activity
... We are a group of scientists trying to find the gene responsible for an orange spot in dogs. Dogs are diploid just like humans, which means that they have two copies (alleles) of each gene. For this exercise, the dominant allele is indicated by “A” and the recessive allele is indicated by “a”. Prete ...
... We are a group of scientists trying to find the gene responsible for an orange spot in dogs. Dogs are diploid just like humans, which means that they have two copies (alleles) of each gene. For this exercise, the dominant allele is indicated by “A” and the recessive allele is indicated by “a”. Prete ...
Hemoglobin
... Types a-thalassemia : If one of the four genes is defective: The individual is termed a silent carrier as no physical manifestations of the disease If two a-globin genes are defective: The individual is designated as having a-thalassemia trait with mild anemia If three a-globin genes are defec ...
... Types a-thalassemia : If one of the four genes is defective: The individual is termed a silent carrier as no physical manifestations of the disease If two a-globin genes are defective: The individual is designated as having a-thalassemia trait with mild anemia If three a-globin genes are defec ...
apbio ch 14 study guide
... heritable units, genes, that retain their separate identities in offspring. o Genes can be sorted and passed on, generation after generation, in undiluted form. ...
... heritable units, genes, that retain their separate identities in offspring. o Genes can be sorted and passed on, generation after generation, in undiluted form. ...
DNA How the Molecule of Heredity Carries, Replicates, and
... •Much of DNA’s sequence-specific information is accessible only when the double helix is unwound. •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. •Human genome is believed to be 250 million nucleotide ...
... •Much of DNA’s sequence-specific information is accessible only when the double helix is unwound. •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. •Human genome is believed to be 250 million nucleotide ...
Early Metazoan Divergence Was About 830 Million Years Ago
... 1996). Another related issue concerns gene duplications in chordate evolution. Many genes in vertebrate genomes may have more than one copy (e.g., enolase, HSP70). In our study we simply chose one rate-constant copy, because our preliminary result has shown that using another gene copy would give a ...
... 1996). Another related issue concerns gene duplications in chordate evolution. Many genes in vertebrate genomes may have more than one copy (e.g., enolase, HSP70). In our study we simply chose one rate-constant copy, because our preliminary result has shown that using another gene copy would give a ...
Predicting Combinations for Alleles in a Zygote Using Punnett
... other from the father) contains genes relating to the same functions of the body. These instructions, however, are often different. Any one of two or more genes that may occur alternatively at a given place on a chromosome is called an allele. In most of the examples we assume that there are two all ...
... other from the father) contains genes relating to the same functions of the body. These instructions, however, are often different. Any one of two or more genes that may occur alternatively at a given place on a chromosome is called an allele. In most of the examples we assume that there are two all ...
Journal of Bacteriology
... incubation of the Sym plasmidless strain RBL1387 in exudate induced neither the Tsr phenotype (Table 1) nor the Hai or Had phenotype (Fig. 1E). Similar results were observed when strain RBL1402, RBL1409, RBL1410, or RBL1412 was used, indicating that the nodD, nodA, nodB, and nodC genes are required ...
... incubation of the Sym plasmidless strain RBL1387 in exudate induced neither the Tsr phenotype (Table 1) nor the Hai or Had phenotype (Fig. 1E). Similar results were observed when strain RBL1402, RBL1409, RBL1410, or RBL1412 was used, indicating that the nodD, nodA, nodB, and nodC genes are required ...
Archaeal Transcription Initiation - IMBB
... jannaschii, two of which are plasmid-encoded (Bult et al., 1996; Grayling et al., 1996). In most cases, the primary sequences of the archaeal histones within one species are more similar to each other than to the sequences of histones in other Archaea, indicating that the original histone gene has u ...
... jannaschii, two of which are plasmid-encoded (Bult et al., 1996; Grayling et al., 1996). In most cases, the primary sequences of the archaeal histones within one species are more similar to each other than to the sequences of histones in other Archaea, indicating that the original histone gene has u ...
Presentation
... • Integrated mixed-methods analysis • Calls for visual analytics tools for visual analytics research-- we are our testbed Oct 8, 2009 ...
... • Integrated mixed-methods analysis • Calls for visual analytics tools for visual analytics research-- we are our testbed Oct 8, 2009 ...
Combination of Reverse Transcription and Multienzyme Restriction
... DNA from viable cells and that from dead cells. In addition to the ethidium monoazide bromide PCR method, reverse-transcription PCR (RT-PCR) can differentiate between viable and dead bacteria because most mRNAs have short half-lives in dead bacteria. Although RT-PCR is time consuming and requires hi ...
... DNA from viable cells and that from dead cells. In addition to the ethidium monoazide bromide PCR method, reverse-transcription PCR (RT-PCR) can differentiate between viable and dead bacteria because most mRNAs have short half-lives in dead bacteria. Although RT-PCR is time consuming and requires hi ...
Molluscan Studies - Oxford Academic
... missing data tended to have ambiguous population assignments. All STRUCTURE figures were produced using DISTRUCT v. 1.1 (Rosenberg, 2004). To describe genetic variation within P. lignaria in more detail, STRUCTURE analysis was run on P. lignaria samples alone. We selected samples with no missing data ...
... missing data tended to have ambiguous population assignments. All STRUCTURE figures were produced using DISTRUCT v. 1.1 (Rosenberg, 2004). To describe genetic variation within P. lignaria in more detail, STRUCTURE analysis was run on P. lignaria samples alone. We selected samples with no missing data ...
FRIZZY PANICLE Drives Supernumerary
... Figure 1. SS phenotypes in bread wheat. A, Schematic representations of a spike (left) and a spikelet (right) from bread wheat N67 and of a theoretical wild-type (WT) spikelet (boxed). B, Schematic illustration of various SS structures: a cluster of spikelets at a rachis node referred to as a MRS, t ...
... Figure 1. SS phenotypes in bread wheat. A, Schematic representations of a spike (left) and a spikelet (right) from bread wheat N67 and of a theoretical wild-type (WT) spikelet (boxed). B, Schematic illustration of various SS structures: a cluster of spikelets at a rachis node referred to as a MRS, t ...