Understanding Autoimmune Disease – a review article for the layman
... which are secreted and circulate in the blood. Surface immunoglobulin is the antigen receptor for B lymphocytes and when it attaches to an antigen the B cell is activated, usually with the help of a TH cell responding to the same antigen. Once the B cell is activated, it undergoes mitotic division t ...
... which are secreted and circulate in the blood. Surface immunoglobulin is the antigen receptor for B lymphocytes and when it attaches to an antigen the B cell is activated, usually with the help of a TH cell responding to the same antigen. Once the B cell is activated, it undergoes mitotic division t ...
Cutaneous Mastocytosis: A Case of Case Report
... and congenital syphilis.8,9 The diagnosis of UP was made in our patient based on the clinical and histopathologic findings. Elevated plasma histamine levels are demonstrated in most children with mastocytosis, especially in those with diffuse CM. Histamine levels may be useful for identifying childr ...
... and congenital syphilis.8,9 The diagnosis of UP was made in our patient based on the clinical and histopathologic findings. Elevated plasma histamine levels are demonstrated in most children with mastocytosis, especially in those with diffuse CM. Histamine levels may be useful for identifying childr ...
Federica Chessa Dr. sc. hum. Dendritic cell function in different renal
... from 300 mOsm/L in the cortex up to 1200 mOsm/L in the inner medulla. A major contribution to the strong osmolarity increase in medulla is given by interstitial sodium. An aspect so far not investigated is whether non-immunologic biophysical factors within the kidney, such as medullary hyperosmolari ...
... from 300 mOsm/L in the cortex up to 1200 mOsm/L in the inner medulla. A major contribution to the strong osmolarity increase in medulla is given by interstitial sodium. An aspect so far not investigated is whether non-immunologic biophysical factors within the kidney, such as medullary hyperosmolari ...
10840-40353-1-SP
... failure, rejection is the first clinical case that should come to mind. Acute renal failure should be diagnosed by emergency physician. Patients with acute renal failure should be hospitalized and nephrologist should be informed quickly. In graft rejections that are not managed very well, the rate o ...
... failure, rejection is the first clinical case that should come to mind. Acute renal failure should be diagnosed by emergency physician. Patients with acute renal failure should be hospitalized and nephrologist should be informed quickly. In graft rejections that are not managed very well, the rate o ...
polycystic kidney
... o probably the most common of all renal fusion anomalies o The anomaly consists of two distinct renal masses lying vertically on either side of the midline and connected at their respective lower poles by a parenchymatous or fibrous isthmus that crosses the midplane of the body . o Fusion of the ren ...
... o probably the most common of all renal fusion anomalies o The anomaly consists of two distinct renal masses lying vertically on either side of the midline and connected at their respective lower poles by a parenchymatous or fibrous isthmus that crosses the midplane of the body . o Fusion of the ren ...
PowerPoint Presentation - Cambridge Clinical Research Facility
... •This multicentre phase 2, randomised, rater blinded trial was of previously untreated patients with early relapsing-remitting multiple sclerosis. Disease activity was confirmed clinically (two or more relapses in the preceding 2 years) and radiologically (one or more enhancing lesions on cranial ma ...
... •This multicentre phase 2, randomised, rater blinded trial was of previously untreated patients with early relapsing-remitting multiple sclerosis. Disease activity was confirmed clinically (two or more relapses in the preceding 2 years) and radiologically (one or more enhancing lesions on cranial ma ...
Outline Approach to the itchy patient Pruritus = the sensation of itch
... • Soap to the axillae, groin, scalp only • Mid potency topical steroid (TAC) ointment to the areas of redness and itch • Severe cases, soak in tub 20 minutes, apply TAC ointment, cover with Saran Wrap and sleep in it ...
... • Soap to the axillae, groin, scalp only • Mid potency topical steroid (TAC) ointment to the areas of redness and itch • Severe cases, soak in tub 20 minutes, apply TAC ointment, cover with Saran Wrap and sleep in it ...
Live Skin Allograft in the Management of Severe Burns
... used successfully in some countries with good results though with very small number of patients reported (20-22). Acceptability has been retarded by cultural beliefs and fear of contacting diseases (23). However, with adequate pre operative counseling we were able to have full acceptance of the proc ...
... used successfully in some countries with good results though with very small number of patients reported (20-22). Acceptability has been retarded by cultural beliefs and fear of contacting diseases (23). However, with adequate pre operative counseling we were able to have full acceptance of the proc ...
Systemic lupus erythematosus and myasthenia gravis
... immune disease with no predilection to involve specific organs, and is characterized by the pres ence of anti‑native DNA and anti‑SM antibodies, which may contribute to the occurrence of sus tained proinflammatory state in the body.1,2 Im mune disorders associated with polyclonal activa tion of ...
... immune disease with no predilection to involve specific organs, and is characterized by the pres ence of anti‑native DNA and anti‑SM antibodies, which may contribute to the occurrence of sus tained proinflammatory state in the body.1,2 Im mune disorders associated with polyclonal activa tion of ...
STUDY OF GLUTAMATE AND ASPARTATE IN BLOOD PLASMA OF
... Introduction. Recently it has been prevailing view that psoriasis is a systemic disorder of multifactorial etiology with genetic and exogenous factors involvement, that results in escalation of functional disorders, metabolic violation and launching of the mechanisms of pathological process formatio ...
... Introduction. Recently it has been prevailing view that psoriasis is a systemic disorder of multifactorial etiology with genetic and exogenous factors involvement, that results in escalation of functional disorders, metabolic violation and launching of the mechanisms of pathological process formatio ...
yahar
... polyarteritis nodosa : anti-HBsAg & HBsAg:HBsAB in the tissues progressive systemic sclerosis : ischemic ulcers mixed connective tissue disorders : presence of anti-Sm antibodies ...
... polyarteritis nodosa : anti-HBsAg & HBsAg:HBsAB in the tissues progressive systemic sclerosis : ischemic ulcers mixed connective tissue disorders : presence of anti-Sm antibodies ...
Massive haemoptysis - e-SAFE
... The small vessel vasculitis leads to skin and joint symptoms in addition to the pulmonary-renal syndrome. Rheumatological autoimmune disease Systemic lupus erythematosus and systemic sclerosis have been associated with the pulmonary-renal syndrome. The vasculitis is caused by immune complex depositi ...
... The small vessel vasculitis leads to skin and joint symptoms in addition to the pulmonary-renal syndrome. Rheumatological autoimmune disease Systemic lupus erythematosus and systemic sclerosis have been associated with the pulmonary-renal syndrome. The vasculitis is caused by immune complex depositi ...
Integumentary System Diseases
... In scleroderma, the tissue gets hard or thick. It can cause swelling or pain in your muscles and joints. Symptoms of scleroderma include calcium deposits in connective tissues, Raynaud’s phenomenon, a narrowing of blood vessels in the hands or feet, swelling of the esophagus, the tube between your t ...
... In scleroderma, the tissue gets hard or thick. It can cause swelling or pain in your muscles and joints. Symptoms of scleroderma include calcium deposits in connective tissues, Raynaud’s phenomenon, a narrowing of blood vessels in the hands or feet, swelling of the esophagus, the tube between your t ...
Systemic Lupus Erythematosus - UC Irvine`s Department of Medicine
... Late 1800s- Sir William Osler initially described the systemic nature and linked rashes to organ involvement 1949- LE cell described by Malcolm Hargraves at Mayo Clinic 1954- ANA described 1971- First set of classification criteria proposed for Lupus 1983- Antiphospholipid antibody syndrom ...
... Late 1800s- Sir William Osler initially described the systemic nature and linked rashes to organ involvement 1949- LE cell described by Malcolm Hargraves at Mayo Clinic 1954- ANA described 1971- First set of classification criteria proposed for Lupus 1983- Antiphospholipid antibody syndrom ...
What is Vitiligo? - Society for Pediatric Dermatology
... Vitiligo (vit-ih-LIE-go) is a condition where individuals develop patches of white or lighter-colored skin. This results from destruction or reduction of melanocytes, the cells that produce pigment in our skin, so that they cannot properly function. The cause of vitiligo is not clearly understood, b ...
... Vitiligo (vit-ih-LIE-go) is a condition where individuals develop patches of white or lighter-colored skin. This results from destruction or reduction of melanocytes, the cells that produce pigment in our skin, so that they cannot properly function. The cause of vitiligo is not clearly understood, b ...
What is Vitiligo? - Society for Pediatric Dermatology
... Vitiligo (vit-ih-LIE-go) is a condition where individuals develop patches of white or lighter-colored skin. This results from destruction or reduction of melanocytes, the cells that produce pigment in our skin, so that they cannot properly function. The cause of vitiligo is not clearly understood, b ...
... Vitiligo (vit-ih-LIE-go) is a condition where individuals develop patches of white or lighter-colored skin. This results from destruction or reduction of melanocytes, the cells that produce pigment in our skin, so that they cannot properly function. The cause of vitiligo is not clearly understood, b ...
superantigens in atopic dermatitis
... Usually, the diaper area is spared, although infants may develop lesions and lichenification at easy to reach crevices: directly below the diaper, extensor surface of the forearm, or back of the hand . If the scalp is involved, it may be very difficult to distinguish AD from seborrheic dermatitis ...
... Usually, the diaper area is spared, although infants may develop lesions and lichenification at easy to reach crevices: directly below the diaper, extensor surface of the forearm, or back of the hand . If the scalp is involved, it may be very difficult to distinguish AD from seborrheic dermatitis ...
Renal revision quiz - Ipswich-Year2-Med-PBL-Gp-2
... Enlarged, cystic kidneys at birth Corticomedullary cysts, shrunken kidneys Large multicystic kidneys, liver cysts, berry aneurysms Cystic degeneration in ESKD Single/multiple cysts in normal-sized kidneys Corticomedullary cysts, shrunken kidneys ...
... Enlarged, cystic kidneys at birth Corticomedullary cysts, shrunken kidneys Large multicystic kidneys, liver cysts, berry aneurysms Cystic degeneration in ESKD Single/multiple cysts in normal-sized kidneys Corticomedullary cysts, shrunken kidneys ...
远球小管
... each human kidney • Renal blood flow肾血 流量 (RBF) – 94% to cortex皮质 – 5% outer medulla髓质 – 1% inner medulla ...
... each human kidney • Renal blood flow肾血 流量 (RBF) – 94% to cortex皮质 – 5% outer medulla髓质 – 1% inner medulla ...
lupus nephritis - Nephro
... • The incidence and prevalence of lupus and LN are influenced by age,gender, ethnicity, geographic region, but across populations, clinically important kidney disease will occur in 40% of patients. • The peak incidence of lupus is age 15 to 45 years, with women to men by 10 : 1. • Among lupus patien ...
... • The incidence and prevalence of lupus and LN are influenced by age,gender, ethnicity, geographic region, but across populations, clinically important kidney disease will occur in 40% of patients. • The peak incidence of lupus is age 15 to 45 years, with women to men by 10 : 1. • Among lupus patien ...
Ventricular Septal Defect ( VSD )
... Control the symptoms of H.F . Prevent the development of pulmonary vascular disease . Surgical closure of defect : Indications : 1. Patient at any age with large defect in whom clinical symptoms , FTT cannot be controlled medically . 2. Supracristal VSD . 3. VSD complicated with AR or subvalvu ...
... Control the symptoms of H.F . Prevent the development of pulmonary vascular disease . Surgical closure of defect : Indications : 1. Patient at any age with large defect in whom clinical symptoms , FTT cannot be controlled medically . 2. Supracristal VSD . 3. VSD complicated with AR or subvalvu ...
how lasers help the skin - Portland Dermatology Clinic
... discomfort is lessened by cooling the skin. Immediate after-effects include temporary swelling and some diffuse redness, but recent advances in technology have decreased the likelihood of bruising. The injured blood vessels are gradually resorbed over the ensuing weeks. Any post-treatment changes in ...
... discomfort is lessened by cooling the skin. Immediate after-effects include temporary swelling and some diffuse redness, but recent advances in technology have decreased the likelihood of bruising. The injured blood vessels are gradually resorbed over the ensuing weeks. Any post-treatment changes in ...
High-frequency ultrasound of skin involvement in
... healthy individuals, these SSc patients displayed large variations between different ultrasound measurements over time in the same individual; during the follow-up, skin thickness decreased and skin echogenicity increased. This study included five different anatomical sites and showed that high-freq ...
... healthy individuals, these SSc patients displayed large variations between different ultrasound measurements over time in the same individual; during the follow-up, skin thickness decreased and skin echogenicity increased. This study included five different anatomical sites and showed that high-freq ...
Hematopoietic stem cell transplantation for autoimmune diseases
... for autoimmune diseases should not be viewed as a cure but rather as changing the natural history of the disease. Investigators should consider this more realistic expectation in justifying mortality endpoints from myeloablative versus non-myeloablative regimens. In fact, similar to syngeneic HSCT i ...
... for autoimmune diseases should not be viewed as a cure but rather as changing the natural history of the disease. Investigators should consider this more realistic expectation in justifying mortality endpoints from myeloablative versus non-myeloablative regimens. In fact, similar to syngeneic HSCT i ...
Systemic scleroderma
Systemic sclerosis or systemic scleroderma is an autoimmune or connective tissue disease. It is characterized by thickening of the skin caused by accumulation of collagen, and by injuries to the smallest arteries. There are two overlapping forms. Limited cutaneous scleroderma is limited to the skin on the face, hands and feet. Diffuse cutaneous scleroderma covers more of the skin, and is at risk of progressing to the visceral organs, including the kidneys, heart, lungs and gastrointestinal tract.Survival is determined by the severity of visceral disease. Prognosis is difficult to predict until the disease differentiates into recognizable subsets. Patients with limited cutaneous scleroderma have a good prognosis, with 10-year survival of 75%, although <10% develop pulmonary arterial hypertension after 10 to 20 years. Patients with diffuse cutaneous scleroderma have a 10-year survival of 55%. Death is most often from pulmonary, heart and kidney involvement, although survival has greatly improved with effective treatment for kidney failure. Immunosuppressive drugs are used, although glucocorticoids have limited application.Annual incidence is 19 per million, and prevalence is 19-75 per 100,000, with a female:male ratio of 3:1, and 8:1 in mid to late childbearing years. Incidence is twice as high among African Americans, and the Choctaw Native Americans in Oklahoma have the highest prevalence in the world (469/100,000). There is some hereditary association, some suggestion of immune reaction (molecular mimicry) to a virus, and some cases caused by toxins.