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Gene Section S100A2 (S100 calcium binding protein A2)
Gene Section S100A2 (S100 calcium binding protein A2)

... kD), calcium-binding proteins that initiate a number of cellular processes such as cell division, motility, secretion, protein synthesis, and membrane permeability through both calcium dependent and independent mechanism. Greater than twenty five different S100 proteins have so far been identified w ...
A New pROM King for the MitoKATP Dance
A New pROM King for the MitoKATP Dance

... protective effects of IPC that is not directly related to the mitoKATP. Thus, pharmacological manipulation alone has proven to be insufficient in identifying mitoKATP components. In this issue of Circulation Research, Foster et al14 combine a high-throughput proteomic screen with pharmacological and ...
Make:targeting signals
Make:targeting signals

... KCa ~ 14 mM for free calmodulin ...
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... voltages exist across the membranes of excitable cells when they are at rest; these voltages are called resting membrane potentials and they exist because of the unequal distribution of Na+, K+, Cl- and protein on either side of the plasma membrane ...
Localization of Leptin Binding Domain in the Leptin Receptor
Localization of Leptin Binding Domain in the Leptin Receptor

... OB-Rb with the glycan-phosphatidylinositol signal sequence from the human placenta alkaline phosphatase (HPAP-S peptide) as described previously (Lin et al., 1990). The S-D(867–1165) mutant was generated by exchanging the extracellular domain of the S(420–496)to-(500–632) mutant and the D(867–1165) ...
PDF - Walter Lab
PDF - Walter Lab

... Endocytosis functions to recycle plasma membrane components, to regulate cell-surface expression of signalling receptors and to internalize nutrients in all eukaryotic cells. Internalization of proteins, lipids and other cargo can occur by one of several pathways that have different, but often overl ...
More than just synaptic building blocks: scaffolding proteins of the
More than just synaptic building blocks: scaffolding proteins of the

... formation of functional synapses in aspiny cerebellar neurons, perhaps via its ability to bring both receptors and cytoskeletal elements into close proximity (Roussignol et al. 2005). Shank proteins are also responsible for shaping the morphology of dendritic spines via the recruitment of Homer in b ...
Lecture 19 Membranes 2: Membrane Proteins
Lecture 19 Membranes 2: Membrane Proteins

... glycosidic bonds to specific Ser, Thr, and Asn residues) • Carbohydrates include ABO and MN blood group antigen-determining structures. • Extracellular part of protein also receptor for influenza virus binding to cells • C-terminal portion on cytosolic side of membrane, interacts with cytoskeletal p ...
Chapter 13 PowerPoint - Hillsborough Community College
Chapter 13 PowerPoint - Hillsborough Community College

... • Nociceptors—sensitive to pain-causing stimuli (examples: extreme heat or cold, excessive pressure, inflammatory chemicals) ...
Special Senses
Special Senses

... superior nasal concha ...
The Outer Membrane of Gram-negative Bacteria and - Beck-Shop
The Outer Membrane of Gram-negative Bacteria and - Beck-Shop

... very hydrophobic, and forms a helix turn helix structure which spans the membrane twice, with a hydrophilic loop on the side of attachment of F1. There is a conserved acidic residue half-way across the membrane in the C-terminal helix. After dissociation, the membranes are permeable to protons. The ...
Eight bacterial proteins, including UDP-N
Eight bacterial proteins, including UDP-N

... Fig. 2. The imperfect tandem hexapeptide repeat structure of eight bacterial proteins. The hexapeptide arrangement was revealed by locating those IG, LG, and VG dipeptide residues which are followed or preceded by lie, Leu, or Val at an [I,V,LHI,V,L] distance of six residues. Such dipeptides as well ...
Osmolarity and Tonic..
Osmolarity and Tonic..

... said to be isotonic. Haemolysis does not occur until the saline solution is less then 0.5%. The point about this definition of tonicity is that it is qualitative and not quantitative. It does imply that permeant solutes will be ineffective because it is essentially a test against a real membrane. A ...
IOBC Hasselt
IOBC Hasselt

... Store at -20°C ...
Coordinated Regulation of AIB1 Transcriptional Activity by
Coordinated Regulation of AIB1 Transcriptional Activity by

... Per-Arnt-Sim domain, which is known to be involved in protein-protein interaction. Three LXXLL motifs, also known as nuclear receptor boxes (for nuclear receptor binding), are centrally located in all three proteins (7–9). In the C terminus, the SRC proteins contain two activation domains, AD1 and A ...
Function of the ubiquitin–proteosome pathway in auxin response
Function of the ubiquitin–proteosome pathway in auxin response

... cloning and characterization of these auxin-response genes suggest that auxin signaling is mediated through the ubiquitin pathway. Recent molecular data on AXR1 and TIR1 function in Arabidopsis are providing new insight into auxin response. ...
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... Composed of 2 glucosamines attached to fatty acids and phosphates Is embedded in the outer membrane Is the toxic part of LPS (endotoxin) ...
11 - Dr. Jerry Cronin
11 - Dr. Jerry Cronin

... one neuron and dendrites of others • Axosomatic—between axon terminals of one neuron and soma of others • Less common types: – Axoaxonic (axon to axon) – Dendrodendritic (dendrite to dendrite) – Somatodendritic (dendrite to soma) ...
Cell - Glow Blogs
Cell - Glow Blogs

... Draw an animal cell and label the features What extra three structures are found in a plant cell? Can you describe the functions of any of these features ...
PPT 2 Eukaryotic Cell Structure
PPT 2 Eukaryotic Cell Structure

... End Show Copyright Pearson Prentice Hall ...
Animal Cell Electronmicrographs
Animal Cell Electronmicrographs

... Agallia constricta showing showing typical cellular organelles The large central nucleus (N) is surrounded by a dense cytoplasm containing endoplasmic reticulum (ER), ribosomes (R), mitochondria (M), and a golgi apparatus (GA) ...
Action Potentials & Nerve Conduction
Action Potentials & Nerve Conduction

... • In the nervous system, different channel types are responsible for transmitting electrical signals over long and short distances: •A) Graded potentials travel over short distances and are activated by the opening of mechanically or chemically gated channels. •B) Action potentials travel over long ...
THE MAMMALIAN TARGET OF RAPAMYCIN (MTOR) AS A
THE MAMMALIAN TARGET OF RAPAMYCIN (MTOR) AS A

... compounds that selectively inhibited proliferation of PTEN-/- cells. Preliminary characterization of these compounds suggest they partially inhibit mTOR through modulation of an Akt regulated target TSC2. Taken together, these data suggest that persistent activation of Akt confers sensitivity to mTO ...
Animal Cells And Plant Cells
Animal Cells And Plant Cells

... Teaching Phase: How will the teacher present the concept or skill to students? The teacher will use the following link to present the material on plant and animal cells: http://cellsalive.com/cells/cell_model.htm 1. The teacher will open two windows in their internet browser with the above link. In ...
Responses to stimulating multiple inputs
Responses to stimulating multiple inputs

... experiment, you block voltage-gated Na and K channels by applying TTX and TEA, respectively. After blocking V-gated Na and K channels, you still observe the currents shown below. You find that these remaining currents are blocked when the Mg concentration is raised. ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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