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Bacteria Binding by DMBT1/SAG/gp-340 Is Confined to
Bacteria Binding by DMBT1/SAG/gp-340 Is Confined to

... the macrophage scavenger receptor (MSR1), the Mac 2-binding protein (Mac-2bp), and MARCO. Both MSR1 and MARCO are known to interact with bacteria (6, 7). In contrast to MARCO (8), the SRCR domain of MSR1 does not seem to be involved in bacteria binding (9, 10). Bacteria binding by MARCO involves an ...
Opposite Polarity of Virus Budding and of Viral Envelope
Opposite Polarity of Virus Budding and of Viral Envelope

... Whereas both FRT and CaCo-2 cells sort similarly influenza hemagglutinin and vesicular stomatitis virus (VSV) G protein, respectively, to apical and basolateral membrane domains, they differ in their handling of two togaviruses, Sindbis and Semliki Forest virus (SFV) . By conventional EM Sindbis vir ...
Synapses lecture 2012 De Camilli final
Synapses lecture 2012 De Camilli final

... neurotransmitters) have slow modulatory actions If axon releases a large amount of neurotransmitter, it will also release neuropeptides that modulate the response of the post-synaptic cell. The neuropeptide prepares the post-synaptic cell to receive a barrage of neurotransmitter. ...
1 Irreversible Enzyme Inhibition Affinity labels for studying enzyme
1 Irreversible Enzyme Inhibition Affinity labels for studying enzyme

... • DFP reacts with the active site serine (Ser-195) of chymotrypsin to form DFP-chymotrypsin • Such organophosphorous inhibitors are used as insecticides or for enzyme research • These inhibitors are toxic because they inhibit acetylcholinesterase (a serine protease that hydrolyzes the neurotransmitt ...
MECHANISMS OF VERTEBRATE SYNAPTOGENESIS
MECHANISMS OF VERTEBRATE SYNAPTOGENESIS

... Signaling pathways involved in regulating vertebrate synaptogenesis. Synaptogenesis is a multistep process involving a myriad of signaling molecules. Prior to synapse formation, secreted molecules such as netrins and semaphorins guide axons to their targets. These axons then encounter priming factor ...
Chloroplasts – Structure and Function
Chloroplasts – Structure and Function

... light energy are situated on the lamellae. At intervals, extra lamellae are inserted to form structures called grana (singular:granum). A chloroplast contains approximately 3000 lamellae -they increase the surface area available for the attachment of extra pigment molecules to trap more light energy ...
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AMPK and mTOR: Antagonist ATP Sensors

... which signal a need to produce more ATP. ...
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... 27.1 ~ Structural, functional, and genetic adaptations contribute to prokaryotic success ...
Proteins
Proteins

... Transcription is the process of making an RNA copy of a gene sequence, called a messenger RNA (mRNA). This occurs in the nucleus of the cell. Translation is the process of translating the sequence of mRNA to a sequence of amino acids that will result in a protein. This occurs in the cytoplasm of the ...
7-3 Movement Through The Membranes
7-3 Movement Through The Membranes

... A liquid mixture of 2 or more substances evenly mixed. • Solvent – The liquid in which the substances are mixed ...
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Folding quality control in the export of proteins by the

... Class I leader peptides required use of Tat pathway Class II leader peptides were pathway agnostic • The state of the protein (folding) determined which pathway was used ...
The Chemical Senses
The Chemical Senses

...  Most patients with a loss of taste actually have a dysfunction of the olfactory system. ...
A commentary on the G2/M transition of the plant cell cycle
A commentary on the G2/M transition of the plant cell cycle

... replication perturbed. Of course any cell afflicted with aphidicolin will stop replicating its DNA, but when the drug is washed ...
Biochemistry I, Spring Term 2003 - Second Exam:
Biochemistry I, Spring Term 2003 - Second Exam:

... 5. Which of the statements regarding enzymes is false? a) Enzymes are usually proteins that function as catalysts. b) Enzymes are usually specific. c) Enzymes may be used many times for a specific reaction. d) The active site of an enzyme remains rigid and does not change shape. 6. The nucleophile t ...
6-10summary
6-10summary

... These channels open or close depending on the presence or absence of an electrical, chemical, or physical stimulus. Some transport proteins do not provide channels but appear to actually translocate the solute-binding site and the solute across the membrane as the transport protein changes shape. ○ ...
Molecular Identification of a SNAP-25
Molecular Identification of a SNAP-25

... modes of membrane attachment, if any, of those proteins remain to be determined. Homologues to mammalian SNAP-25 have been found in a variety of organisms ranging from unicellular organisms to plants, fungi, and higher eukaryotes (40). Disassembly of the fully assembled SNARE complex is performed by ...
Presynaptic Modulation of the Retinogeniculate Synapse
Presynaptic Modulation of the Retinogeniculate Synapse

... Modulatory projections from brainstem nuclei and intrinsic thalamic interneurons play a significant role in modifying sensory information as it is relayed from the thalamus to the cortex. In the lateral geniculate nucleus (LGN), neurotransmitters released from these modulatory inputs can affect the ...
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LDL

... • The peroxisome proliferator-response has gained considerable interest due to its association with metastatic hepatocellular carcinomas in rodents. The mechanism by which peroxisome proliferators cause cancer is not clear - these compounds do not bind directly and damage DNA. ...
Oocyte-Specific Expression of Growth/Differentiation Factor-9
Oocyte-Specific Expression of Growth/Differentiation Factor-9

... proteins, which are capable of inducing de novo cartilage and bone formation and appear to be essential for normal skeletal development during mammalian embryogenesis (13-l 8); and giiai cell-derived neurotrophic factor, which can promote the survival of midbrain dopaminergic neurons (19). The biolo ...
FIGURE LEGENDS FIGURE 16.1 Scanning electron micrograph of a
FIGURE LEGENDS FIGURE 16.1 Scanning electron micrograph of a

... which fails to occur if myosin function is inhibited. Modified from Lin et al. (1996). (B) Linkage of the actin cytoskeleton to a permissive surface is required for forward advance. Actin polymerized at the leading edge of the growth cone (right) is swept toward the rear. If the actin meshwork is no ...
cellular respiration study guide
cellular respiration study guide

... 15. Label the diagram below of the activities occurring on the ECT. ...
91.510_ch8_part1
91.510_ch8_part1

... Physical properties of proteins Many websites are available for the analysis of individual proteins. ExPASy and ISREC are two excellent resources. The accuracy of these programs is variable. Predictions based on primary amino acid sequence (such as molecular weight prediction) are likely to be more ...
Hydrogen peroxide-induced changes in intracellular pH of
Hydrogen peroxide-induced changes in intracellular pH of

... Epidermal bioassay demonstrated that benzylamine, a membrane-permeable weak base, can mimick hydrogen peroxide (H2O2) to induce stomatal closure, and butyric acid, a membrane-permeable weak acid, can partly abolish the H2O2-induced stomatal closure. Confocal pH mapping with the probe 5-(and-6)-carbo ...
A dsRNA Based Screen Identifies Novel Proteins Involved in
A dsRNA Based Screen Identifies Novel Proteins Involved in

... activation due to Hh, and they suggested that it may play a role in the phosphorylation of Ci. In 2005, Collins et al. screened for mutations that were able to suppress or enhance a hypomorphic Hh phenotype in the wing, which was the result of C756-Gal4 driven expression of Smo RNAi. They were able ...
Transcriptional Regulation II
Transcriptional Regulation II

... measure some “average” over a population of cells. • The population of cells is seldom in sync (same state). • The closer a population of cells is to its in vivo state the less homogeneous it is. • The closer a population of cells is to its in vivo state the harder (time, effort, money) it is to mea ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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