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Practice Guideline: Focused Update
Practice Guideline: Focused Update

... The ACC/AHA practice guidelines address patient populations (and health care providers) residing in North America. As such, drugs that are not currently available in North America are discussed in the text without a specific class of recommendation. For studies performed in large numbers of subjects ...
Loeffler Endocarditis_ Background, Pathophysiology
Loeffler Endocarditis_ Background, Pathophysiology

... myocardial fibrosis. Substantially better survival rates may be seen in less symptomatic patients who have milder forms of the disease. As noted, this rate may reflect underdiagnosis of clinically inapparent disease, as for other types of cardiomyopathy. ...
Cardiovascular Diseases and its dental implications
Cardiovascular Diseases and its dental implications

... – Infective endocarditis (IE) is defined as an infection of the endocardial surface of the heart which may include one or more heart valves. – Its intracardiac effects include severe valvular insufficiency, which may lead to intractable congestive heart failure and myocardial abscesses. – If left u ...
PACES Cardiology notes 1. Aortic valve replacement 2. Mitral valve
PACES Cardiology notes 1. Aortic valve replacement 2. Mitral valve

... Sudden cardiac death Who should receive antibiotic prophylaxis for IE? NICE guidelines in 2008 - No longer recommended for dental procedures, routine GI, GU or minor surgery. - Recommended if surgery or procedure at site with known or suspected infection. - Instead warn patients of symptoms and of i ...
Cardiology Step 3 Review
Cardiology Step 3 Review

... inspiration. Increased R-sided pressure exerted by noncompliant pericardium as heart moved inferiorly by descending diaphragm during inspiration. ...
Infective Endocarditis
Infective Endocarditis

... Subcutaneous Nodules ...
Regurgitant Systolic Murmurs Chatper 15
Regurgitant Systolic Murmurs Chatper 15

... but stops before P2 whereas the murmur of TR persists through and engulfs P2 • Increases with inspiration (Carvallo sign) & does not radiate well to the axillary region ...
Valvular Heart Disease - Home
Valvular Heart Disease - Home

... – Dilating LV with progressive dysfunction  EF (even with mild symptoms). – Timing of surgery is important; needs to be done before significant deterioration of LV function/EF. ...
Pediatric rheumatic:issues on moving to adult care 20mins
Pediatric rheumatic:issues on moving to adult care 20mins

... (Benzathine Injection every 21 days) Until when?...18?...21?..40?...for life? ...
Slide 1
Slide 1

... MVP with mitral regurgitation is no longer considered a high risk valve lesion and prophylaxis is no longer recommended. Although MVP is associated with an increased risk of endocarditis, there are no convincing data that antibiotic prophylaxis is effective in preventing episodes of endocarditis ...
SGD 2: RHD
SGD 2: RHD

... • Typical microorganisms from two separate blood cultures* • Persistently positive blood culture, defined as recovery of a microorganism consistent w/ infective endocarditis from: – Blood cultures drawn >12 hrs apart – All of three, majority of four or more separate blood cultures, with first and la ...
SGD 2: RHD
SGD 2: RHD

... • Typical microorganisms from two separate blood cultures* • Persistently positive blood culture, defined as recovery of a microorganism consistent w/ infective endocarditis from: – Blood cultures drawn >12 hrs apart – All of three, majority of four or more separate blood cultures, with first and la ...
high yield - Wayne State University
high yield - Wayne State University

... PVC falls on middle of T wave, bad b/c ventricle is vulnerable to developing VT Retinal hemorrhages w/ central white spot, suggestive of infectious endocarditis Rapid ventricular filling, heard in CHF/mitral regurg Atrial contraction into stiff LV, heard in AS/HTN/hypertrophic cardiomyopathy Acute b ...
1 Pathophysiology Name Chapter 24: Alterations of Cardiovascular
1 Pathophysiology Name Chapter 24: Alterations of Cardiovascular

... connective tissue within the myocardium and trigger an autoimmune response. ...
Ventricular Septal Defect - Children`s Heart Federation
Ventricular Septal Defect - Children`s Heart Federation

... usually fade away to nothing. After the first year, the child will be monitored infrequently by a cardiologist. ...
Ventricular Septal Defect - Children`s Heart Federation
Ventricular Septal Defect - Children`s Heart Federation

... Most children are completely well, active, and gaining weight a few days after surgery. He or she will have a scar down the middle of the chest, and there may be small scars where drain tubes were used. These fade very rapidly in most children, but they will not go altogether. Smaller scars on the h ...
Aortic Regurgitation - Cormedicalgroup.com
Aortic Regurgitation - Cormedicalgroup.com

... becoming infected (endocarditis). This risk increases during procedures in which bacteria can enter the blood stream and adhere to the valve, which in turn can make the valve become infected. Dental procedures (including a professional dental cleaning) and certain surgical procedures may introduce b ...
Pulmonary Valve Stenosis and Regurgitation
Pulmonary Valve Stenosis and Regurgitation

... get blood past the blockage. Normally the pulmonary valve has three cusps. If these cusps are malformed, the valve may become narrowed (stenotic) or leaky (regurgitant or insufficiency). Pulmonary valve stenosis is much more common than regurgitation. The stenosis and regurgitation or both can be mi ...
Pulmonary Atresia - American Heart Association
Pulmonary Atresia - American Heart Association

... Pulmonary Atresia / Intact Ventricular Septum ...
Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy

... elevated in the endocardium of the lateactivated region, whereas phospholamban is ...
Inflammatory Heart Disease
Inflammatory Heart Disease

... output and all the bad stuff that ensues. It can lead to heart failure or pulmonary complications (so make sure you listen to those lung sounds!). Stenosis increases workload of the chamber behind the valve, and regurgitation causes excess blood volume in chamber behind the valve...got that? Basical ...
Anticoagulants
Anticoagulants

... • The AHA Prevention of Infective Endocarditis Committee recommended that prophylaxis be given only to a high-risk group of patients before dental procedures that involve manipulation of either gingival tissue or the periapical region of the teeth or perforation of oral mucosa ...
Loeffler`s endocarditis - European Heart Journal
Loeffler`s endocarditis - European Heart Journal

... Rest perfusion images demonstrated a global subendocardial perfusion defect ( Panel D—left arrow, and see Supplementary data online, Videos S4 and S5). Delayed enhancement imaging demonstrated global subendocardial uptake of gadolinium (Panels E and F, arrows). CMRI confirmed the presence of a left ...
VALVULAR HEART DISEASE Case Goals and Objectives
VALVULAR HEART DISEASE Case Goals and Objectives

... inciting bacteremia  Acute endocarditis is caused by S. aureus (50-70%)  In the non-IVDU, the aortic valve is involved ...
Cardiovascular Cases 3
Cardiovascular Cases 3

... • Left heart failure ...
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Infective endocarditis



Infective endocarditis is a form of endocarditis. It is an inflammation of the inner tissues of the heart, the endocardium (such as its valves). It is caused by infectious agents, or pathogens, which are usually bacterial but other organisms can also be responsible.The valves of the heart do not receive any dedicated blood supply. As a result, defensive immune system mechanisms (such as white blood cells) cannot directly reach the valves via the bloodstream. If an organism (such as bacteria) attaches to a valve surface and forms a vegetation, the host's immune response is blunted. The lack of blood supply to the valves also has implications for treatment, since drugs also have difficulty reaching the infected area.Normally, blood flows smoothly through these valves. If they have been damaged - from rheumatic fever, for example - the risk of bacterial attachment is increased.
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