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Functional Genomics Screening with Invitrogen™ LentiArray
Functional Genomics Screening with Invitrogen™ LentiArray

... describe the library design concepts, the assay development, initial screening results and validation of specific identified hits. The gRNAs are designed to primarily 5’ coding exons of a target gene using our CRISPR design tool to maximize knock-out efficiency and minimize off-target effects. Each ...
IBO 2005 Theory Paper - International Biology Olympiad
IBO 2005 Theory Paper - International Biology Olympiad

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Underwriting Glossary - centurionagencyltd.com
Underwriting Glossary - centurionagencyltd.com

... BENIGN: not cancerous; a tumor that does not spread and is limited in growth. BIOPSY: process of viewing living tissue. A sample of tissue is removed from an organ and then prepared for viewing under the microscope. BLADDER: see Urinary Bladder. BLOOD PRESSURE: a measure of how well blood circulates ...
Cell Structure - The Physics Teacher.ie
Cell Structure - The Physics Teacher.ie

... 1. Identify the parts of a plant cell as seen under light microscope 2. Identify the parts of an animal cell as seen under light microscope 3. Give the function of each of the following parts: Cell wall, cell membrane, nucleus, cytoplasm, vacuole and chloroplast 4. Identify the ultra structure and g ...
The Metabolic Activities of Escherichia coli during the
The Metabolic Activities of Escherichia coli during the

... response of the infected cells showed that 9 % gave the lytic response, it may be asked why no synthesis of protein or nucleic acid was detected in the first 45 min. (the normal latent period for A ) when the infected cells were incubated in the amino-acid medium. It is in fact possible that all the ...
Blood Vessels, Day 2
Blood Vessels, Day 2

... • Local factors change pattern of blood flow w/in capillary beds • Response to chemical changes in interstitial fluids ...
Unit 3: Dynamic Equilibrium: The Human Animal
Unit 3: Dynamic Equilibrium: The Human Animal

... people in certain parts of Asia. One day, a doctor in Indonesia noticed some chickens staggering around, a symptom often seen in people with beriberi. It turned out that the chickens had been eating white rice—the same kind of rice that was being eaten by human beriberi sufferers. White rice has had ...
Circulatory System
Circulatory System

... Veins return blood to the heart once it has passed through the capillary system Except for the pulmonary vein, all veins carry deoxygenated blood The walls of veins contain connective tissue and smooth muscle but are not as thick because they do not have the same applied pressure as the arteries Lar ...
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Control of Blood Glucose

... Acinar cells – exocrine cells that produce digestive enzymes that are secreted into the duodenum The endocrine cells are organized into the islets of Langerhans ...
Morphological changes induced in bacteria as evaluated by electron
Morphological changes induced in bacteria as evaluated by electron

... prevalence of pathogens causing opportunistic infections in humans and animals underscores the imperative need to develop new and effective biocides. Since 1946, several papers were published on the use of electron microscopy as a means to provide relevant information about discrete cellular phenome ...
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Bacterial morphology, metabolism and growth

... • Rigid peptidoglycan (murein) layer • Except: Archaebacteria (pseudoglycan and pseudomurein) and mycoplasmas (no cell wall) • Peptidoglycan provides rigidity and determines the shape of a bacteria • Gram-negative bacteria. + outer membranes ...
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Transport In Plants Just like humans, plants have a transport system

... This is the transport of organic food such as sucrose and amino acids in the plant through the phloem vessels. Glucose, the product of photosynthesis is the most important food of the plant. Because from it, it makes most of its other nutrients. Glucose is converted into an other more complex sugar ...
Slide 1 - Skyline R2 School
Slide 1 - Skyline R2 School

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Gamete_Cell_Division_teacher

... centromere of the chromosomes  The homologous chromosomes line up across the equator ...
Biology STARR-EOC Review http://nvhsvikings.wikispaces.com/file
Biology STARR-EOC Review http://nvhsvikings.wikispaces.com/file

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Chapter 21 - Circulatory
Chapter 21 - Circulatory

... Provides blood flow to the brain by either the internal carotid artery or the basilar artery. The internal carotid enters the cranial cavity through the carotid foramen. The basilar artery is formed by the convergence of the two vertebral arteries that come up through the transverse foramen of the c ...
The Respiratory System - Course
The Respiratory System - Course

... • Introduce oxygen into the blood stream which delivers oxygen to organs and tissues that need it. • Not let food system go anywhere butthe thebrain digestive •It works with the nervous because sendstract signals to the lungs to breathe. ...
CD63 Is a Component of Weibel
CD63 Is a Component of Weibel

... From the Centerfor Hemostasis and Thrombosis Research, Division of Hematology-Oncology, New England Medical Center, Boston; and the Department of Anatomy and Cellular Biology, Tufts University School of Medicine, Boston MA. ...
Abstract Template
Abstract Template

... attenuate the inflammatory response and encourage neural cell interactions with the electrode. Dexamethasone phosphate (DP) and valproic acid (VA), both antiinflammatory agents, with VA having additional neuroprotective effects, were incorporated within poly(3,4-ethylenedioxythiophene) (PEDOT) as bi ...
unit-4-notes-cell-membranes
unit-4-notes-cell-membranes

... – Hyperosmotic (hypertonic) solutions have a higher concentration of solutes on the outside of the membrane than inside the membrane. – Hypo-osmotic (hypotonic) solutions have a lower concentration of solutes on the outside of the membrane than inside the membrane. – Iso-osmotic (isotonic) solutions ...
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21development

... • Another hot research areas involves stem cells. – As relatively unspecialized cells, they continually reproduce themselves and under appropriate conditions, they differentiate into specialized cell types. – The adult body has various kinds of stem cells, which replace nonreproducing specialized ...
Urinary System Interactions
Urinary System Interactions

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PPT
PPT

... energy production. All higher organisms require O2. Unless the O2 diffuses into the body, they must have a mechanism and a system for bringing in O2 and eliminating the CO2 that results from cellular respiration. ...
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Unit

... Bring water from a pond and place a few drops of it on a slide and observe under the microscope. You will observe many microscopic organism moving in the water. Among them there may be a slipper shaped paramaecuim visible. Paramaecuim is a unicellular organism which moves due to the constant beating ...
How Can Cryptic Epitopes Trigger Autoimmunity? By Antonio
How Can Cryptic Epitopes Trigger Autoimmunity? By Antonio

... containing different sets of proteases, such as granzymes. It is also possible that ligand binding may influence processing as discussed below. As a consequence of their differential expression, these epitopes will not induce tolerance in the thymus, but it will induce a specific response in periphe ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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