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Urinary System Interactions
Endocrine System
Nervous System
• Kidneys dispose of nitrogenous
wastes; maintain fluid, electrolyte,
and acid—base balance of blood;
produce the hormone erythropoietin;
renal regulation of Na+ and water
balance essential for blood pressure
homeostasis and hormone transport
in the blood
• ADH, aldosterone, ANP, and other
hormones help regulate renal
reabsorption of water and electrolytes
• Kidneys dispose of nitrogenous wastes;
maintain fluid, electrolyte, and acid-base
balance of blood; renal regulation of Na+,
and Ca2+ content in EOF essential for normal neural function
• Neural controls involved in micturition;
sympathetic nervous system activity
triggers the renin—angiotensin mechanism
Cardiovascular System
• Kidneys dispose of nitrogenous wastes;
maintain fluid, electrolyte, and acid-base
balance of blood; renal regulation of Na”
and water balance essential for blood
pressure homeostasis. Na+, and Ca2+
reguIation help maintain normal heart
function
• Systemic arterial blood pressure is the
driving force for glomerular filtration; heart
secretes atrial natriuretic peptide; blood
vessels Q transport nutrients, oxygen, etc.
to urinary organs
Immune System
• Kidneys dispose of nitrogenous
vvastes; maintain fluid, electrolyte, and
acid—base balance of blood
• By returning leaked plasma fluid to
cardiovascular system, lymphatic
vessels help ensure normal systemic
blood pressure needed for kidney
function; immune cells protect urinary
organs from infection, cancer,
and other foreign
Muscular System
Respiratory System
• Kidneys dispose of nitrogenous wastes;
maintain fluid, electrolyte, and acid—base
balance of blood; renal regulation of Naf
KT and Ca2+ content EOF crucial for muscle
activity • Muscles of pelvic diaphragm and
external urethral sphincter function in voluntary control of micturition; creatinine is
a nitrogenous waste product that must be
excreted by the kidneys
f• Kidneys dispose of nitrogenous
wastes; maintain fluid, electrolyte,
»a_ and acid-base balance of blood
• Respiratory system provides oxygen
required by kidney cells; disposes
of carbon dioxide; cells in the lungs
convert angiotensin I to angiotensin ll
Digestive System
• Kidneys dispose of nitrogenous
wastes; maintain fluid, electrolyte, and
acid-base balance of blood;
also, metabolize vitamin D to the
active form needed for calcium
absorption
• Digestive organs provide nutrients
needed for kidney cell health; liver
synthesizes most urea, a nitrogenous
vvaste that must be excreted by
the kidneys
lntegumentary System
• Kidneys dispose of nitrogenous wastes; maintain
fluid, electrolyte, and acidbase balance of blood
• Skin provides external
protective barrier; serves
as site for water loss (via
perspiration); vitamin D
synthesis site
Reproductive System
• Kidneys dispose of nitrogenous wastes;
maintain fluid, electrolyte, and acid-base
balance of blood
Skeletal System
• Kidneys dispose of nitrogenous wastes;
maintain fluid, electrolyte, and acid-base
balance of blood
• Bones of rib cage provide some
protection to kidneys