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Campbell Biology Concepts and Connections, 7th
Campbell Biology Concepts and Connections, 7th

... 28) A scientist performs a controlled experiment. This means that A) the experiment proceeds at a slow pace to guarantee that the scientist can carefully observe all reactions and process all experimental data. B) two experiments are conducted, one differing from the other by only a single variable. ...
Single gene-based distinction of individual microbial
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... In the first part of the technique, acrylamide is polymerized on microbial cells, trapping cells in emulsion droplets (Figure 1). In this state, cell walls and other cellular components can be enzymatically removed, allowing microbial genomes to be exposed to further reactions. The exposed genomes do ...
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Cellular and molecular mechanisms involved in branching

... 00435.2004.—Recent comparative studies have shown that, in many instances, the genetic network underlying the development of distinct organ systems is similar in invertebrate and vertebrate organisms. Genetically well-characterized, simple invertebrate model systems, such as Caenorhabditis elegans a ...
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Conceptual Hierarchy Human Body Systems and

... Understand and apply knowledge of the functions and interconnections of the major human body systems including the breakdown in structure or function that disease causes. The human organism has systems for digestion, respiration, reproduction, circulation, excretion, movement, control, and coordinat ...
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... The simplest form of movement is diffusion, in which solutes move from an area of high concentration to an area of low concentration; diffusion is directly related to molecular kinetic energy. Diffusion does not require energy input by cells. The movement of a solute from an area of low concentratio ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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