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The human RNA-binding protein RBFA promotes the maturation of
The human RNA-binding protein RBFA promotes the maturation of

... Assembly and maturation of a fully functional ribosome is a demanding but fundamental feature of cellular metabolism. Budding yeast, for example, can produce 2000 ribosomes per minute (1), reflecting the demands of protein synthesis. Across almost all characterized species, the ribosome is composed ...
The Human Body—An Orientation Anatomy—Levels of Study The
The Human Body—An Orientation Anatomy—Levels of Study The

... A sagittal section divides the body (or organ) into left and right parts A median, or midsagittal, section divides the body (or organ) into equal left and right parts A frontal, or coronal, section divides the body (or organ) into anterior and posterior parts A transverse, or cross, section divides ...
structural and ultrastructural data on side effects of cisplatin in
structural and ultrastructural data on side effects of cisplatin in

... Histological and ultrastructural investigations of the kidney showed the appearance of some significant modifications which seemed to evolve gradually, starting from the moment of treatment. The first histological alterations could be noticed as soon as 24 hours after the treatment, but they were ve ...
Myc Requires Distinct E2F Activities to Induce S Phase
Myc Requires Distinct E2F Activities to Induce S Phase

... propose that the induction of specific E2F activities is an essential component in the Myc pathways that control cell proliferation and cell fate decisions. Introduction The stimulation of cell proliferation involves the induction of immediate early gene products such as c-Myc, as well as the subseq ...
15.3 Homeostasis - Liver Functions
15.3 Homeostasis - Liver Functions

... Branches of the hepatic artery and hepatic portal vein supply blood to the capillaries (sinusoids) of each lobule Running between the lobules in the opposite direction to the blood, are fine ducts (canaliculi), carrying bile from the liver cells towards the main bile duct ...
Hairy cell leukemia, an uncommon B
Hairy cell leukemia, an uncommon B

... studies indicate its effectiveness. The most used scheme consists of administering 0.1 mg/kg/day in a continuous infusion for 7 days. In a non-randomized study, there was evidence proving that there was no statistically significant difference in the response and toxicity ranges between infusions (24 ...
11. Circulatory and resp
11. Circulatory and resp

... II. Thoracic Cavity As previously mentioned, the body cavity of mammals, including human beings, is divided by the diaphragm into the thoracic cavity and the abdominal cavity. The heart and lungs are in the thoracic cavity. The heart is a pump for the cardiovascular system, and the lungs are organs ...
Functional coupling of microtubules to membranes
Functional coupling of microtubules to membranes

... In vivo, organelles do not move with a simple linear trajectory from A to B. Their path is interspersed with many stops and starts and, indeed, frequent changes of direction. The saltatory (‘stop–start’) motility could relate to the competing activity of opposing motors (i.e. a ‘tug-of-war’ between ...
Explainer: What is skin?
Explainer: What is skin?

... same time, nerves within the skin relay important information about the world around us by sensing pain, textures and temperatures. The skin you scrub every day in the bath or shower is only the outermost layer, called the epidermis (Epih-DER-mis). The epidermis is constantly shedding dead cells fro ...
Insulin-like Growth Factor I Receptor Signaling in
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... 1) and transduced cell lines, either with an empty vector (Lane 2) or with the WT IGF-IR vector (Lane 3). This last cell line expresses a considerable amount of the IGF-IR protein (arrow) compared with parental or vector-transduced H19-7 cells. The other lanes in Fig. 1C are lysates from different c ...
Transport in Invertebrates
Transport in Invertebrates

... 7. The endocardium lines the inner surface of the heart; it consists of connective tissue and endothelial tissue. 8. Internally, a wall called the septum separates the heart into right and left halves. 9. The heart has two upper, thin-walled atria and two lower, thick-walled ventricles. a. The atria ...
Influence of Antibiotic and E5 Monoclonal Immunoglobulin
Influence of Antibiotic and E5 Monoclonal Immunoglobulin

... between the present data and data previously published by our group. For an interaction time of 2 h, at 8 µM DODAB, 0% viability for S. aureus was previously obtained (17) consistent with the 5% viability at 12 µM DODAB for a smaller interaction time, 1 h (Table 1). One should notice the very large ...
division plane orientation in plant cells
division plane orientation in plant cells

... Plants are sessile organisms composed of non-motile cells locked into position by rigid cell walls. Plants grow by a combination of cell elongation and cell division with no cell migration, making a cell’s initial position relative to that of its neighbors difficult to adjust. Consequently, proper o ...
The Molecular Basis of Self-Avoidance
The Molecular Basis of Self-Avoidance

... arise from the same cell than if they come from a homologue, and not at all if they come from a cell with a different modality,” although other mechanisms involving interactions with skin or underlying tissue were not ruled out. Yau (1976) confirmed their findings and proposed that the branches of a c ...
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... (absorption is tuned to internal bodily needs) Certain food chemicals (e.g., phytate, oxalate) lower absorption by tying up the mineral There is competition for absorption machinery Metal ions antagonism (Cu-Zn; Zn-Fe; etc.) occurs at ion channels during the transmural passage phase of absorption Vi ...
CHAPTER-6 NCERT SOLUTIONS
CHAPTER-6 NCERT SOLUTIONS

... 1. Inside the lungs, the blood capillaries surround the alveoli. The exchange of gases takes place between the blood of the capillaries and the gases present in the alveoli. Thus alveoli are the site for exchange of gases. 2. During the process of inhalation, the lungs get filled up with air as rib ...
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A group of related organs that perform specific functions organ system

... veins capillaries smooth muscle cardiac muscle skeletal muscle ligaments ligaments tendons ...
Ch. 6 notes
Ch. 6 notes

... Forensic Science II: Body Systems, Chapter 6 © 2012 Cengage Learning. All Rights Reserved ...
Plk4/SAK/ZYG-1 in the regulation of centriole
Plk4/SAK/ZYG-1 in the regulation of centriole

... centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, centriole assembly is either amplified or decreased corresponding to levels of Plk4/SAK [30,31]. Defects resul ...
earthworm dissection
earthworm dissection

... forming larger vessels. Blood is returned to the aortic arches through the dorsal vessel, which runs along the top of the digestive tract. 3) Identify the dorsal vessel, which runs along the top of the intestine. Follow it forward toward the esophagus. Gently move aside any organs that obscure your ...
CELL DIVISION AND DNA SYNTHESIS IN TETRAHYMENA
CELL DIVISION AND DNA SYNTHESIS IN TETRAHYMENA

... In the same context, the criticalness of the time at which D N A synthesis begins is also demonstrated by the change in the utilization of H 3thymidine of the medium for macronuclear D N A synthesis. Amino acid deprivation before D N A synthesis begins prevents the subsequent uptake of H3-thymidine ...
New roles for Nanos in neural cell fate determination revealed by
New roles for Nanos in neural cell fate determination revealed by

... on a daily basis, has a short and accessible embryonic development, and is amenable to gene expression analysis and manipulation. The cnidarian nervous system is of particular interest because it is continuously being renewed in the adult animals and because the molecular mechanisms that specify neu ...
vocabulary - Squarespace
vocabulary - Squarespace

... Purulent: Containing or producing pus. Pustule: Raised spot on the skin containing pus. Rhytidectomy: Surgical removal of excess skin to eliminate wrinkles. Commonly referred to as a face lift. Rubella: Contagious viral skin infection, Commonly called German measles. Scabies: A contagious, parasitic ...
Architectural remodeling of the tonoplast during fluid
Architectural remodeling of the tonoplast during fluid

... and endocytosis.43 In each of these processes, membrane vesicles composed of lipid bilayers and various membrane proteins are pinched off from one organelle and delivered to other subcellular or extracellular compartments that are undergoing expansion or reconstruction.43 During cell growth, much of ...
Chapter 3 Vocabulary Integumentary System • Abrasion: A scraping
Chapter 3 Vocabulary Integumentary System • Abrasion: A scraping

... Purulent: Containing or producing pus. Pustule: Raised spot on the skin containing pus. Rhytidectomy: Surgical removal of excess skin to eliminate wrinkles. Commonly referred to as a face lift. Rubella: Contagious viral skin infection, Commonly called German measles. Scabies: A contagious, parasitic ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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