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Systemic and cell type-specific gene expression patterns in scleroderma skin.
Systemic and cell type-specific gene expression patterns in scleroderma skin.

... by ⬎2-fold in at least three of the 27 experiments and analyzed them by hierarchical clustering in both the gene and experiment dimension (Fig. 1). The dendrogram representing the results from clustering the tissues samples according to similarity in their patterns of expression of these 2,776 genes ...
Evolutionary aspects of non-cell-autonomous regulation in vascular
Evolutionary aspects of non-cell-autonomous regulation in vascular

... In seedless plants, the knowledge on cell wall composition, lipidomics and hormonal regulatory networks is limited compared to angiosperms. However, genome sequencing in the moss Physcomitrella patens and the spike moss Selaginella moellendorfii has recently provided a solid basis for future analyse ...
Reciprocal signaling between Drosophila epidermal muscle
Reciprocal signaling between Drosophila epidermal muscle

... initial determination of mesodermal fate (Leptin, 1991). The different somatic muscles comprise an array of 30 different types of myotubes which develop, through the second half of embryonic development, in close proximity to the basal surfaces of the epidermis (Bate, 1990). The identity of each of ...
Connective tissue
Connective tissue

... array –period accounted for by gaps fall in dark bands ...
somatic hybridization - GCG-42
somatic hybridization - GCG-42

... • From the protoplast solution of known density (about 105 protoplast/ml) about 1 ml suspension is poured on sterile and cooled down nutrient medium in Petri ...
Cell surface monoamine oxidases: enzymes in search of a function
Cell surface monoamine oxidases: enzymes in search of a function

... whether the soluble form is a product of a different gene or a cleavage product of the transmembrane form of SSAO. In man there is evidence that the soluble enzyme is formed by a proteolytic cleavage of the membrane-bound molecule, since the N-terminal sequence of the soluble form isolated from the ...
The VirE3 protein of Agrobacterium mimics a host cell function
The VirE3 protein of Agrobacterium mimics a host cell function

... reporter gene, which allows yeast cells to grow in a histidinedeficient medium. The interaction between VirE3 and AtKAPa was specific because it did not occur with lamin C (Figure 3A, lane 4), a known nonspecific Y2H activator best suited to eliminate false-positive interactions (Bartel et al, 1993) ...
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... Plant shoots display positive phototropism: when illuminated from one direction, the shoot proceeds to grow in that direction. ...
CLINICAL SOCIETY MEETING 30-01-2015
CLINICAL SOCIETY MEETING 30-01-2015

... • The main immunohistochemical markers expressed by these cells are vimentin, CD99 and alpha inhibin. • The serum tumor markers are estradiol, inhibin, and anti-Müllerian hormone. ...
THE CELL CYCLE OF PHYTOPLANKTON : COUPLING CELL
THE CELL CYCLE OF PHYTOPLANKTON : COUPLING CELL

... phase they called S, for synthesis (Figure 1A). This phase is preceded by a first gap (G1 ) and separated from mitosis (M) by a second gap (G2 ). Gametic cells of diploid organisms undergo a differentiated cycle called meiosis in which a round of DNA replication is followed by two rounds of cell div ...
1.3mb
1.3mb

... cellular metabolism (eg. Inactivate p53 & Rb). 6. Host DNA and protein synthesis shot-off during viral DNA replication, to ensure the synthesis of viral DNA and structure genes. 7. Apoptosis is actively inhibited by viral functions in all stages of viral replication (encoding Bcl2, inactivating Rb & ...
Protophloem Differentiation in Early Arabidopsis
Protophloem Differentiation in Early Arabidopsis

... side of the cotyledon and was accompanied by two adjacent cells. The three cells were tightly linked, and were probably generated by two longitudinal divisions during late embryogenesis (Fig. 1F). The specification of PPs was completed in the midvein and in the distal loops forming the secondary vei ...
The importance of Src homology 2 domain-containing
The importance of Src homology 2 domain-containing

... content of ␣-helices and to participate in protein-protein interactions.22,23 Since then, more than 1300 SAM-containing proteins have been identified in various organisms, ranging from yeast to humans. SAM domains can be found in all subcellular compartments and participate in a wide variety of cell ...
Better check late than never: The chromosome segregation
Better check late than never: The chromosome segregation

... Aneuploidy is the result of errors in chromosome segregation and is manifested in two out of three cancers. The spindle assembly checkpoint (SAC) has evolved to prevent aneuploidy by inhibiting onset of anaphase until all chromosomes are properly aligned and attached. When the SAC is satisfied and c ...
The Bovine CD1 Family Contains Group 1 CD1 Proteins, but No
The Bovine CD1 Family Contains Group 1 CD1 Proteins, but No

... Flow cytometric analysis of bovine thymocytes, bovine PBMC, and 293T cells transfected with full-length boCD1B3 and boCD1A transcript was performed with a panel of Abs against human and boCD1 (Fig. 2 and data not shown). The Abs SBU-T6 (17), CC14 (18), CC20 (19, 20), and CC122 (19, 21) are known to ...
Factors PU.1, Spi-B, and Spi-C Transformation
Factors PU.1, Spi-B, and Spi-C Transformation

... in humans and by the Sfpi1 gene in mice. PU.1 is required to ...
Chemokine-Induced Migration Inhibits Integrin
Chemokine-Induced Migration Inhibits Integrin

... 10) and their downstream effector actin-binding protein cofilin (11). Cofilin phosphorylation by Lin-11-Isl-1-Mec-3 kinase in response to semaphorin inhibits cofilin ability to bind and depolymerize pointed ends of F-actin, which inhibits F-actin turnover in neuron growth cones. Moreover, three rece ...
Opposite Effects of Tor1 and Tor2 on Nitrogen Starvation
Opposite Effects of Tor1 and Tor2 on Nitrogen Starvation

... 1993). Cells carrying disruption of tor21 at the chromosomal locus and expressing the nmt1-tor21 construct were grown to midlog phase and then shifted to repressing conditions and samples were taken for cell number counting and cell morphology examination. As seen in Figure 1, A and B, cells shifted ...
Morphogen-induced Platelet Activation and Cell Signalling
Morphogen-induced Platelet Activation and Cell Signalling

... messenger RNAs (mRNAs) that have recently been demonstrated to be functional, leading to protein synthesis especially in activated platelets. Therefore, platelets are genetically predetermined cells and mRNA expression level within them is fixed. Thus, it would be interesting to study and elaborate ...
BI 201 Human Anatomy & Physiology
BI 201 Human Anatomy & Physiology

... What would the effect on the resting membrane potential be if the permeability of the plasma membrane to K+ was reduced? Why? ...
Studies on sulphatases. 6. The localization of arylsulphatase in the
Studies on sulphatases. 6. The localization of arylsulphatase in the

... Arylsulphatase is apparently concentrated in the granular material of the cytoplasm of rat-liver cells and is absent from the nuclei and from the soluble components of the cytoplasm. The distribution of the enzyme as found by mechanical cytological separation agrees with the broad histochemical pict ...
The Rice TAL Effector–Dependent Resistance
The Rice TAL Effector–Dependent Resistance

... oryzae strains deliver members of the large AvrBs3-related effector family into host cells via the bacterial type III secretion system (Yang and White, 2004). AvrBs3-like effectors, also referred to as transcription activator–like (TAL) effectors (Yang et al., 2006), function as transcription factor ...
1st Semester Final Exam Study Guide
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... a. The first column is the INDEPENDENT variable (what the experimenter controls) b. Starting in the 2nd column is the DEPENDENT variable (what is measured/observed) c. All columns should include UNITS in parentheses to show what you measured in. ...
10 m
10 m

...  An example of an internal signal occurs at the M phase checkpoint  In this case, anaphase does not begin if any kinetochores remain unattached to spindle microtubules  Attachment of all of the kinetochores activates a regulatory complex, which then activates the enzyme separase  Separase allow ...
Review Article Oncogene: The Dominant Evil
Review Article Oncogene: The Dominant Evil

... that normally control what kind of cell it is and how often it divides. When a protooncogene mutates (changes) into an oncogene, it becomes a "bad" gene that can become permanently turned on or activated when it is not supposed to be. When this happens, the cell grows out of control, which can lead ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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