Protruding Vulva Mutants Identify Novel Loci and Wnt
... once and fuse with the hypodermal syncytium. In addition, P3.p can also adopt a fourth cell fate called F, for fused, in which P3.p fuses with the hypodermal syncytium without dividing at all (Ferguson and Horvitz 1985; Sternberg and Horvitz 1986). The F fate is adopted by P3.p in ⵑ50% of wild-type ...
... once and fuse with the hypodermal syncytium. In addition, P3.p can also adopt a fourth cell fate called F, for fused, in which P3.p fuses with the hypodermal syncytium without dividing at all (Ferguson and Horvitz 1985; Sternberg and Horvitz 1986). The F fate is adopted by P3.p in ⵑ50% of wild-type ...
The Muir-Torre syndrome - UCSF Pathology
... symptoms and signs. Many syndromes are named after the physicians credited with first reporting the association; these are ʺeponymousʺ syndromes (see also the list of eponymous diseases, many of which are called ʺsyndromesʺ). Otherwise, disease features or presumed causes, as well as references ...
... symptoms and signs. Many syndromes are named after the physicians credited with first reporting the association; these are ʺeponymousʺ syndromes (see also the list of eponymous diseases, many of which are called ʺsyndromesʺ). Otherwise, disease features or presumed causes, as well as references ...
Marrow-Derived Facilitating Cells Transplantation: Role of Bone
... development of graft-vs-host disease (GVHD). The identification of cell populations that are capable of supporting allogeneic stem cell (SC) engraftment and the induction of tolerance without inducing GVHD could expand the use of this therapy. CD8ⴙTCRⴚ facilitating cells (FC) have been shown to prom ...
... development of graft-vs-host disease (GVHD). The identification of cell populations that are capable of supporting allogeneic stem cell (SC) engraftment and the induction of tolerance without inducing GVHD could expand the use of this therapy. CD8ⴙTCRⴚ facilitating cells (FC) have been shown to prom ...
A Conditional System to Specifically Link Disruption of
... with both spatial and temporal control. As a result, conditional gene disruption has become a critical tool for understanding gene function during development, homeostasis, as well as in disease states (Rajewsky, 2007; Schmidt-Supprian and Rajewsky, 2007). Fluorescent reporter alleles have proved to ...
... with both spatial and temporal control. As a result, conditional gene disruption has become a critical tool for understanding gene function during development, homeostasis, as well as in disease states (Rajewsky, 2007; Schmidt-Supprian and Rajewsky, 2007). Fluorescent reporter alleles have proved to ...
insider - The Paleo Diet
... article Dr. Cordain suggested that specific substances known as dietary lectins may be involved in both the inflammation of the gut and in facilitating the movement of bacteria from the gut into the blood stream. ...
... article Dr. Cordain suggested that specific substances known as dietary lectins may be involved in both the inflammation of the gut and in facilitating the movement of bacteria from the gut into the blood stream. ...
introduction to the paleolithic diet
... big obstacle to getting more calories from the environment is the fact that many plants are inedible. Grains, beans and potatoes are full of energy but all are inedible in the raw state as they contain many toxins. There is no doubt about that- please don’t try to eat them raw, they can make you ver ...
... big obstacle to getting more calories from the environment is the fact that many plants are inedible. Grains, beans and potatoes are full of energy but all are inedible in the raw state as they contain many toxins. There is no doubt about that- please don’t try to eat them raw, they can make you ver ...
Fuel cells for non-domestic buildings
... submit at least eight of the ten sets of questions from this series of modules to Energy in Buildings and Industry for the Energy Institute to mark. Anyone achieving at least eight out of ten correct answers on eight separate articles qualifies for an Energy Institute CPD certificate. This can be ob ...
... submit at least eight of the ten sets of questions from this series of modules to Energy in Buildings and Industry for the Energy Institute to mark. Anyone achieving at least eight out of ten correct answers on eight separate articles qualifies for an Energy Institute CPD certificate. This can be ob ...
- Wiley Online Library
... Nevertheless, we believe that clathrin-independent endocytosis in pancreatic b cells definitely requires GTP hydrolysis and dynamin participation. Fast endocytosis is an actin-dependent process Actin has been proposed to be a crucial factor in endocytosis, although its exact role is still elusive. W ...
... Nevertheless, we believe that clathrin-independent endocytosis in pancreatic b cells definitely requires GTP hydrolysis and dynamin participation. Fast endocytosis is an actin-dependent process Actin has been proposed to be a crucial factor in endocytosis, although its exact role is still elusive. W ...
Antimicrobial mechanisms of phagocytes and bacterial evasion
... hostile response, certain bacterial species have developed evasive strategies that often involve the secretion of effectors to co-opt the cellular machinery of the host. In this Review, we present an overview of the antimicrobial defences of the host cell, with emphasis on macrophages, for which pha ...
... hostile response, certain bacterial species have developed evasive strategies that often involve the secretion of effectors to co-opt the cellular machinery of the host. In this Review, we present an overview of the antimicrobial defences of the host cell, with emphasis on macrophages, for which pha ...
Examination of the role of signal transduction and oxidative stress in
... signal generated by activation of PKC stimulates the activity of pre-existing Jun homodimers and thereby increases their ability to activate c-jun transcription. The most common post-translational modification known to modulate protein activity is phosphorylation (Cohen, 1982). Indeed, examination ...
... signal generated by activation of PKC stimulates the activity of pre-existing Jun homodimers and thereby increases their ability to activate c-jun transcription. The most common post-translational modification known to modulate protein activity is phosphorylation (Cohen, 1982). Indeed, examination ...
Phosphatidylcholine traffic to the vacuole
... ER to Golgi transport, a null mutation in VPS8, which inhibits Golgi to PVC transport, or temperature-sensitive and null mutations in END4, which inhibit endocytosis from the plasma membrane. Monomethylation or dimethylation of the primary amine head-group of M-C6NBD-PE is sufficient for sorting to ...
... ER to Golgi transport, a null mutation in VPS8, which inhibits Golgi to PVC transport, or temperature-sensitive and null mutations in END4, which inhibit endocytosis from the plasma membrane. Monomethylation or dimethylation of the primary amine head-group of M-C6NBD-PE is sufficient for sorting to ...
New twists on embryonic patterning
... organizing centers. In posterior mesoderm, the zone of polarizing activity (ZPA) produces SHH, which acts in a feedback loop with fibroblast growth factors (FGFs) in the apical ectodermal ridge (AER). This, in turn, promotes outgrowth of the apical mesoderm, generating what is called the progress zo ...
... organizing centers. In posterior mesoderm, the zone of polarizing activity (ZPA) produces SHH, which acts in a feedback loop with fibroblast growth factors (FGFs) in the apical ectodermal ridge (AER). This, in turn, promotes outgrowth of the apical mesoderm, generating what is called the progress zo ...
Direct Evidence of Active and Rapid Nuclear
... turgor pressure and became spherical. The heterochromatin structure could be seen just inside the nucleus. SYTO16 fluorescence in some chloroplasts appeared in this focal plane. The green fluorescence in the cytoplasm disappeared probably because the emission spectra of fluorescein changed following ...
... turgor pressure and became spherical. The heterochromatin structure could be seen just inside the nucleus. SYTO16 fluorescence in some chloroplasts appeared in this focal plane. The green fluorescence in the cytoplasm disappeared probably because the emission spectra of fluorescein changed following ...
Orthologs of Arabidopsis thaliana stomatal bHLH
... (see Tables S1 and S2 in the supplementary material). Despite strong similarity within these two domains, SPCH, MUTE and FAMA each contain unique features, allowing orthologs to be assigned unambiguously. FAMA and SPCH contain N-terminal acidic domains (with limited sequence similarity between them, ...
... (see Tables S1 and S2 in the supplementary material). Despite strong similarity within these two domains, SPCH, MUTE and FAMA each contain unique features, allowing orthologs to be assigned unambiguously. FAMA and SPCH contain N-terminal acidic domains (with limited sequence similarity between them, ...
From DEPARTMENT OF MEDICAL
... between Wnt1 and Wnt5a in mDA neuron development in vivo. Based on these results, we developed a combined Wnt protocol to promote the generation of mDA neurons from neural and embryonic stem cells in vitro. We conclude that coordinated Wnt actions promote mDA neuron development in vivo and in stem c ...
... between Wnt1 and Wnt5a in mDA neuron development in vivo. Based on these results, we developed a combined Wnt protocol to promote the generation of mDA neurons from neural and embryonic stem cells in vitro. We conclude that coordinated Wnt actions promote mDA neuron development in vivo and in stem c ...
PDF
... Kristopher L. Schmidt1,2, Nancy Marcus-Gueret1,2, Adetayo Adeleye1,2, Jordan Webber1, David Baillie2 and Eve G. Stringham1,2,* The shape changes that are required to position a cell to migrate or grow out in a particular direction involve a coordinated reorganization of the actin cytoskeleton. Altho ...
... Kristopher L. Schmidt1,2, Nancy Marcus-Gueret1,2, Adetayo Adeleye1,2, Jordan Webber1, David Baillie2 and Eve G. Stringham1,2,* The shape changes that are required to position a cell to migrate or grow out in a particular direction involve a coordinated reorganization of the actin cytoskeleton. Altho ...
RNA Tumour Virus Phosphoproteins
... (FeLV), gibbon ape lymphosarcoma virus (GaLV), and the endogenous cat type C virus (RD-II4), we report here the occurrence of multiple phosphorylated species in the pI2 phosphoproteins of the Rauscher (R) and wild mouse (WM) strains of murine leukaemia virus (MuLV). The number and relative proportio ...
... (FeLV), gibbon ape lymphosarcoma virus (GaLV), and the endogenous cat type C virus (RD-II4), we report here the occurrence of multiple phosphorylated species in the pI2 phosphoproteins of the Rauscher (R) and wild mouse (WM) strains of murine leukaemia virus (MuLV). The number and relative proportio ...
The zebrafish midblastula transition - Development
... 7 minutes (data not shown); hence cycle lengthening is due to lengthening of the period of interphase. Our methods do not further subdivide the interphase period. The cycles also lose synchrony (Fig. 2B). At first, not all of cells begin to lengthen their cycles simultaneously and lengthening if it ...
... 7 minutes (data not shown); hence cycle lengthening is due to lengthening of the period of interphase. Our methods do not further subdivide the interphase period. The cycles also lose synchrony (Fig. 2B). At first, not all of cells begin to lengthen their cycles simultaneously and lengthening if it ...
Role of cancer-associated fibroblasts in breast cancer development
... organs, fibroblasts have a low proliferation index and minimum metabolic capacity. By contrast, during wound healing and in cancers, fibroblasts become activated, start to proliferate, secrete higher amounts of ECM components, and acquire contractile features (Polyak and Kalluri, 2010). In tumors, t ...
... organs, fibroblasts have a low proliferation index and minimum metabolic capacity. By contrast, during wound healing and in cancers, fibroblasts become activated, start to proliferate, secrete higher amounts of ECM components, and acquire contractile features (Polyak and Kalluri, 2010). In tumors, t ...
Semen WS - St Paul`s School Intranet
... Once inside the ovum the tail is lost and the head, containing the nucleus, becomes the male gamete. The nuclear membranes disappear so that the two nuclei can fuse. This is fertilisation. The cell is now referred to as a zygote. ...
... Once inside the ovum the tail is lost and the head, containing the nucleus, becomes the male gamete. The nuclear membranes disappear so that the two nuclei can fuse. This is fertilisation. The cell is now referred to as a zygote. ...
Selection and the Origin of Cells
... with the suggestion that these might have become populated by nucleic acid molecules that gradually took over the evolutionary process. However, although it is reasonable to suppose that clay crystals subjected to rounds of crystallization and fragmentation could evolve by selection, in the last fif ...
... with the suggestion that these might have become populated by nucleic acid molecules that gradually took over the evolutionary process. However, although it is reasonable to suppose that clay crystals subjected to rounds of crystallization and fragmentation could evolve by selection, in the last fif ...
The Gram Reaction and Cell Composition: Nucleic
... low LP in the analyses of the whole cells. The work of Newton (1953)and our own recent unpublished observations show that Gram-negative organisms lose significant amounts of the acidsoluble components when washed in distilled water, whereas Gram-positive organisms generally do not. Since all the org ...
... low LP in the analyses of the whole cells. The work of Newton (1953)and our own recent unpublished observations show that Gram-negative organisms lose significant amounts of the acidsoluble components when washed in distilled water, whereas Gram-positive organisms generally do not. Since all the org ...
Identification of a host protein essential for assembly of immature
... NATURE | VOL 415 | 3 JANUARY 2002 | www.nature.com ...
... NATURE | VOL 415 | 3 JANUARY 2002 | www.nature.com ...
Asymmetric cell division in C. elegans - Development
... fuse with the epidermal syncytium called hyp7 (Sulston and Horvitz, 1977). We find that loss-of-function mutations in egl20 cause reversals in the polarity of the V5 daughter cell fates. In egl-20 mutants, V5.a often becomes a seam cell while V5.p fuses with hyp7. Thus, egl-20 mutants continue to di ...
... fuse with the epidermal syncytium called hyp7 (Sulston and Horvitz, 1977). We find that loss-of-function mutations in egl20 cause reversals in the polarity of the V5 daughter cell fates. In egl-20 mutants, V5.a often becomes a seam cell while V5.p fuses with hyp7. Thus, egl-20 mutants continue to di ...